Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



B3GALT2 Gene

protein-coding   GIFtS: 51
GCID: GC01M193147

UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide...

  See B3GALT2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 21 2     beta-3-galt22
Beta-1,3-GalTase 22 3     beta3Gal-T22
UDP-Galactose:2-Acetamido-2-Deoxy-D-Glucose 3beta-Galactosyltransferase 22 3     Beta3Gal-T23
GLCT22 5     Beta3GalT23
BETA3GALT22     EC 2.4.1.-3
Beta-1,3-Galactosyltransferase 22     EC 2.4.18

External Ids:    HGNC: 9171   Entrez Gene: 87072   Ensembl: ENSG000001626307   OMIM: 6030185   UniProtKB: O438253   

Export aliases for B3GALT2 gene to outside databases

Previous GC identifers: GC01M190938 GC01M188662 GC01M189614 GC01M190436 GC01M189879 GC01M191414 GC01M164383


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for B3GALT2 Gene:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II
membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and
UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine).
The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence
contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or
alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas
beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during
embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other
beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes a protein that functions in N-linked glycoprotein
glycosylation and shows strict donor substrate specificity for UDP-galactose. (provided by RefSeq, Jul 2008)

GeneCards Summary for B3GALT2 Gene:
B3GALT2 (UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2) is a protein-coding gene. Diseases associated with B3GALT2 include sipple syndrome. GO annotations related to this gene include UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. An important paralog of this gene is B3GNT3.

UniProtKB/Swiss-Prot: B3GT2_HUMAN, O43825
Function: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal
beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue,
albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and
glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or
alpha-N-acetylgalactosamine (alpha-GalNAc) residues




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the B3GALT2 gene promoter:
         C/EBPbeta   MEF-2   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   POU3F2   POU2F1   POU2F1a   POU2F1b   aMEF-2   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidB3GALT2 promoter sequence
   Search Chromatin IP Primers for B3GALT2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat B3GALT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q31   Ensembl cytogenetic band:  1q31.2   HGNC cytogenetic band: 1q31

B3GALT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GALT2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M193147:  view genomic region     (about GC identifiers)

Start:
193,147,860 bp from pter      End:
193,155,784 bp from pter
Size:
7,925 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: B3GT2_HUMAN, O43825 (See protein sequence)
Recommended Name: Beta-1,3-galactosyltransferase 2  
Size: 422 amino acids; 49213 Da
Cofactor: Manganese (By similarity)
Secondary accessions: B2RAB1 Q9BZQ9

Explore the universe of human proteins at neXtProt for B3GALT2: NX_O43825

Explore proteomics data for B3GALT2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn75, Asn100, Asn119, Asn176, Asn226
  • Modification sites at PhosphoSitePlus
  • 4 DME Specific Peptides for B3GALT2 (O43825)
     VMKTDSD  FCSGTGY  YHDIIQQ  AIRQTWG 


    See B3GALT2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003774.1  
    ENSEMBL proteins: 
     ENSP00000356404  

    B3GALT2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for B3GALT2
    OriGene Custom MassSpec
    OriGene Custom Protein Services for B3GALT2
    GenScript Custom Purified and Recombinant Proteins Services for B3GALT2
    Novus Biologicals B3GALT2 Proteins
    Novus Biologicals B3GALT2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for B3GALT2 

    B3GALT2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for B3GALT2
    OriGene Custom Antibody Services for B3GALT2
    Novus Biologicals B3GALT2 Antibodies
    Search for Antibodies for B3GALT2 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for B3GALT2
    LSBio Antibodies in human, mouse, rat for B3GALT2

    B3GALT2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for B3GALT2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for B3GALT2
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for B3GALT2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    B3GT: Beta 3-glycosyltransferases

    1 InterPro protein domain:
     IPR002659 Glyco_trans_31

    Graphical View of Domain Structure for InterPro Entry O43825

    ProtoNet protein and cluster: O43825

    1 Blocks protein domain: IPB002659 Glycosyl transferase

    UniProtKB/Swiss-Prot: B3GT2_HUMAN, O43825
    Similarity: Belongs to the glycosyltransferase 31 family


    Find genes that share domains with B3GALT2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B3GT2_HUMAN, O43825
    Function: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal
    beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue,
    albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and
    glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or
    alpha-N-acetylgalactosamine (alpha-GalNAc) residues

         Genatlas biochemistry entry for B3GALT2:
    UDP galactose

         Enzyme Numbers (IUBMB): EC 2.4.12 EC 2.4.1.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008378galactosyltransferase activity ----
    GO:0008499UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity IEA--
         
    Find genes that share ontologies with B3GALT2           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for B3galt2):
     behavior/neurological  growth/size/body 

    Find genes that share phenotypes with B3GALT2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for B3GALT2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for B3GALT2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for B3GALT2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for B3GALT2

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat B3GALT2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate B3GALT2 (see all 39):
    hsa-miR-106a hsa-miR-25 hsa-miR-519a hsa-miR-374c hsa-miR-93 hsa-miR-23a hsa-miR-4293 hsa-miR-526b*
    SwitchGear 3'UTR luciferase reporter plasmidB3GALT2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for B3GALT2
    Predesigned siRNA for gene silencing in human, mouse, rat B3GALT2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for B3GALT2

    Clone
    Products:
         
    OriGene clones in human, mouse for B3GALT2 (see all 6)
    OriGene ORF clones in mouse, rat for B3GALT2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: B3GALT2 (NM_003783)
    Sino Biological Human cDNA Clone for B3GALT2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for B3GALT2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B3GALT2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for B3GALT2
    Browse ESI BIO Cell Lines and PureStem Progenitors for B3GALT2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GALT2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    B3GT2_HUMAN, O43825: Golgi apparatus membrane; Single-pass type II membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    plasma membrane2
    cytosol1
    endoplasmic reticulum1
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with B3GALT2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for B3GALT2 About    
    See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolic pathways0.38
    2Glycosphingolipid biosynthesis - lacto and neolacto series
    Glycosphingolipid biosynthesis - lacto and neolacto series


    Find genes that share SuperPaths with B3GALT2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    2 Kegg Pathways  (Kegg details for B3GALT2):
        Glycosphingolipid biosynthesis - lacto and neolacto series
    Metabolic pathways

    UniProtKB/Swiss-Prot: B3GT2_HUMAN, O43825
    Pathway: Protein modification; protein glycosylation

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for B3GALT2
    Interactions:

        Search GeneGlobe Interaction Network for B3GALT2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for B3GALT2 (ENSP000003564044) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    B3GNT5ENSP000003161734STRING: ENSP00000316173
    B4GALT1ENSP000003690554STRING: ENSP00000369055
    FUT2ENSP000003757484STRING: ENSP00000375748
    FUT3ENSP000003056034STRING: ENSP00000305603
    B4GALT2ENSP000003492934STRING: ENSP00000349293
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006486protein glycosylation IEA--
    GO:0009312oligosaccharide biosynthetic process IEA--

    Find genes that share ontologies with B3GALT2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for B3GALT2 (B3GT2)

    1 HMDB Compound for B3GALT2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Manganesemanganese 7439-96-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for B3GALT2 gene: 
    NM_003783.3  

    Unigene Cluster for B3GALT2:

    UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
    Hs.518834  [show with all ESTs]
    Unigene Representative Sequence: NM_003783
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000367434(uc001gtc.4)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat B3GALT2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate B3GALT2 (see all 39):
    hsa-miR-106a hsa-miR-25 hsa-miR-519a hsa-miR-374c hsa-miR-93 hsa-miR-23a hsa-miR-4293 hsa-miR-526b*
    SwitchGear 3'UTR luciferase reporter plasmidB3GALT2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for B3GALT2
    Predesigned siRNA for gene silencing in human, mouse, rat B3GALT2
    Clone
    Products:
         
    OriGene clones in human, mouse for B3GALT2 (see all 6)
    OriGene ORF clones in mouse, rat for B3GALT2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: B3GALT2 (NM_003783)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for B3GALT2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B3GALT2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for B3GALT2
    OriGene qSTAR qPCR primer pairs in human, mouse for B3GALT2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat B3GALT2
      QuantiTect SYBR Green Assays in human, mouse, rat B3GALT2
      QuantiFast Probe-based Assays in human, mouse, rat B3GALT2

    Additional mRNA sequence: 

    AF288390.1 AK314116.1 BC022507.1 Y15060.1 

    2 DOTS entries:

    DT.411694  DT.95265050 

    Selected AceView cDNA sequences (see all 33):

    BC022507 AW069816 Y15060 AI393902 BP374190 AI141592 AA426162 CK818941 
    AW103171 BM126337 AA887696 BQ017425 BI549637 AA424868 BX643256 BG706170 
    BI544952 BX510089 D81474 BX418449 BX431199 BE699313 R37009 BX460919 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    B3GALT2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    B3GALT2 Expression
    About this image


    B3GALT2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Zeugopod Growth Plate
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Adipose (Muscoskeletal System)    fully expand to see all 2 entries
             Body Subcutaneous White Adipose
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Epithelial Cells
             Podocytes Podocyte Layer
    B3GALT2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    B3GALT2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.518834

    UniProtKB/Swiss-Prot: B3GT2_HUMAN, O43825
    Tissue specificity: Detected in heart and brain

        Custom PCR Arrays for B3GALT2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for B3GALT2
    OriGene qSTAR qPCR primer pairs in human, mouse for B3GALT2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat B3GALT2
    QuantiTect SYBR Green Assays in human, mouse, rat B3GALT2
    QuantiFast Probe-based Assays in human, mouse, rat B3GALT2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GALT2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for B3GALT2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia B3galt21 , 5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, more1, 5 89.97(n)1
    94.55(a)1
      1 (62.52 cM)5
    268781  NM_020025.41  NP_064409.31 
     1436406645 
    chicken
    (Gallus gallus)
    Aves B3GALT21 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, more 81.04(n)
    91.23(a)
      769122  XM_001231893.3  XP_001231894.1 
    lizard
    (Anolis carolinensis)
    Reptilia B3GALT26
    UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase,...
    92(a)
    1 ↔ 1
    GL343267.1(1134156-1135418)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004874401 beta-1,3-galactosyltransferase 2-like 75.69(n)
    84.8(a)
      100487440  XM_002932145.2  XP_002932191.1 
    zebrafish
    (Danio rerio)
    Actinopterygii b3galt21 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, more 64.51(n)
    68.59(a)
      404633  NM_207101.1  NP_996984.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons GALT11 GALT1 43.09(n)
    28.15(a)
      839224  NM_102445.3  NP_174003.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g02292001 Os06g0229200 44.22(n)
    26.8(a)
      4340564  NM_001063748.1  NP_001057213.1 


    ENSEMBL Gene Tree for B3GALT2 (if available)
    TreeFam Gene Tree for B3GALT2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for B3GALT2 gene
    B3GNT32  B3GNT22  B3GNT52  B3GALT52  B3GALT12  B3GNT42  B3GALT42  B3GNT72  
    B3GNT82  B3GNT62  B3GALNT12  B3GNT92  
    6 SIMAP similar genes for B3GALT2 using alignment to 1 protein entry:     B3GT2_HUMAN:
    B3GALT1    B3GALNT1    B3GALT5    B3GNT5    B3GNT6    B3GNT7

    Find genes that share paralogs with B3GALT2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus
    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for B3GALT2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv466994CNV Loss19166990
    nsv832148CNV Gain17160897
    nsv872831CNV Gain21882294
    esv275335CNV Gain+Loss21479260

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing B3GALT2
    DNA2.0 Custom Variant and Variant Library Synthesis for B3GALT2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 603018    OMIM disorders: --

    1 disease for B3GALT2:    
    About MalaCards
    sipple syndrome

    2 diseases from the University of Copenhagen DISEASES database for B3GALT2:
    Parathyroid carcinoma     Sipple syndrome

    Find genes that share disorders with B3GALT2           About GenesLikeMe

    Genetic Association Database (GAD): B3GALT2

    Export disorders for B3GALT2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for B3GALT2 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with B3GALT2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta- nacetyl-galactosamine beta-1,3-galactosyltransferase family. (PubMed id 9582303)1, 2, 3, 9 Amado M.... Clausen H. (J. Biol. Chem. 1998)
    2. Cloning of a human UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta- galactosyltransferase catalyzing the formation of type 1 chains. (PubMed id 9417100)1, 2, 3 Kolbinger F.... Katopodis A.G. (J. Biol. Chem. 1998)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. (PubMed id 11318611)1, 2 Sood R....Carpten J.D. (Genomics 2001)
    6. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    7. Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF MS for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein. (PubMed id 18565761)1 Irungu J....Desaire H. (J. Am. Soc. Mass Spectrom. 2008)
    8. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    10. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 8707 HGNC: 917 AceView: B3GALT2 Ensembl:ENSG00000162630 euGenes: HUgn8707
    ECgene: B3GALT2 Kegg: 8707 H-InvDB: B3GALT2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for B3GALT2 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GALT2
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_430

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for B3GALT2 gene:
    Search GeneIP for patents involving B3GALT2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for B3GALT2   OriGene RNAi products in human, mouse, rat for B3GALT2  
     OriGene qPCR primer pairs and template standards for B3GALT2   OriGene Protein Over-expression Lysate for B3GALT2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for B3GALT2  
     OriGene qSTAR qPCR primer pairs in human, mouse for B3GALT2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for B3GALT2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for B3GALT2   OriGene Custom Protein Services for B3GALT2  

     
     
     Block miRNA regulation of human, mouse, rat B3GALT2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing B3GALT2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat B3GALT2 Predesigned siRNA for gene silencing in human, mouse, rat B3GALT2
     QuantiFast Probe-based Assays in human, mouse, rat B3GALT2 QuantiTect SYBR Green Assays in human, mouse, rat B3GALT2
     Custom PCR Arrays for B3GALT2 Search Chromatin IP Primers for B3GALT2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat B3GALT2  Search GeneGlobe Interaction Network for B3GALT2
     Regulatory tfbs in B3GALT2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for B3GALT2 GenScript cDNA clones with any tag delivered in your preferred vector for B3GALT2
     GenScript Custom Assay Services for B3GALT2 GenScript Custom overexpressing Cell Line Services for B3GALT2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for B3GALT2 (B3GT2)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for B3GALT2
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     B3GALT2 antibodies
     B3GALT2 proteins
     B3GALT2 lysates
     Search for Antibodies for B3GALT2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for B3GALT2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for B3GALT2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GALT2
     SwitchGear 3'UTR luciferase reporter plasmids for B3GALT2
     SwitchGear Promoter luciferase reporter plasmids for B3GALT2
     Search ThermoFisher Antibodies for B3GALT2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B3GALT2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for B3GALT2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for B3GALT2
     LSBio Antibodies in human, mouse, rat for B3GALT2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for B3GALT2
      Search eBioscience for proteins for B3GALT2
      Search eBioscience for elisas for B3GALT2
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      B3GALT2 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4