Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

B3GALT1 Gene

protein-coding   GIFtS: 49
GCID: GC02P168639

UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 11 2     beta3GalT12
Beta-1,3-GalTase 12 3     Beta3Gal-T13
UDP-Galactose:Beta-N-Acetyl-Glucosamine-Beta-1,3-Galactosyltransferase 12 3     Beta3GalT13
Beta-1,3-Galactosyltransferase 12     EC 2.4.1.-3
beta-3-galt12     EC 2.4.18
beta3Gal-T12     EC 2.4.1.628

External Ids:    HGNC: 9161   Entrez Gene: 87082   Ensembl: ENSG000001723187   OMIM: 6030935   UniProtKB: Q9Y5Z63   

Export aliases for B3GALT1 gene to outside databases

Previous GC identifers: GC02P166727 GC02P167216 GC02P168878 GC02P168879 GC02P168500 GC02P168383 GC02P160555


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for B3GALT1 Gene:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II
membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and
UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine).
The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence
contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or
alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas
beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during
embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other
beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is expressed exclusively in the brain. The encoded protein
shows strict donor substrate specificity for UDP-galactose. (provided by RefSeq, Jul 2008)

GeneCards Summary for B3GALT1 Gene: 
B3GALT1 (UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1) is a protein-coding gene. Diseases associated with B3GALT1 include colon adenocarcinoma, and adenocarcinoma, and among its related super-pathways are Metabolism. GO annotations related to this gene include UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. An important paralog of this gene is B3GNT3.

UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6
Function: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal
beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of
glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc)
or alpha-N-acetylgalactosamine (alpha-GalNAc) residues




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_005403.17  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the B3GALT1 gene promoter:
         c-Fos   AP-1   JunB   FosB   Fra-1   Roaz   JunD   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidB3GALT1 promoter sequence
   Search SABiosciences Chromatin IP Primers for B3GALT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B3GALT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24.3   Ensembl cytogenetic band:  2q24.3   HGNC cytogenetic band: 2q24.3

B3GALT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GALT1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P168639:  view genomic region     (about GC identifiers)

Start:
168,675,182 bp from pter      End:
168,727,366 bp from pter
Size:
52,185 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6 (See protein sequence)
Recommended Name: Beta-1,3-galactosyltransferase 1  
Size: 326 amino acids; 37993 Da
Cofactor: Manganese (By similarity)
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (Probable)
Secondary accessions: D3DPB8 Q53SS2

Explore the universe of human proteins at neXtProt for B3GALT1: NX_Q9Y5Z6

Explore proteomics data for B3GALT1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y5Z6

  • 3 DME Specific Peptides for B3GALT1 (Q9Y5Z6)
     VMKTDSD  FCSGTGY  NLTLKTL 

    B3GALT1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    B3GALT1 Protein Expression
    REFSEQ proteins: NP_066191.1  
    ENSEMBL proteins: 
     ENSP00000376456   ENSP00000303740  

    Human Recombinant Protein Products for B3GALT1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for B3GALT1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for B3GALT1
    GenScript Custom Purified and Recombinant Proteins Services for B3GALT1
    Novus Biologicals B3GALT1 Proteins
    Novus Biologicals B3GALT1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane NAS9582303

    B3GALT1 for ontologies           About GeneDecksing



    B3GALT1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for B3GALT1
    GenScript Custom Superior Antibodies Services for B3GALT1
    Novus Biologicals B3GALT1 Antibodies
    Abcam antibodies for B3GALT1
    Browse Antibodies at Cloud-Clone Corp. 
    Search ThermoFisher Antibodies for B3GALT1
    LSBio Antibodies in human, mouse, rat for B3GALT1 

    Assay Products for B3GALT1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for B3GALT1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for B3GALT1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    B3GT: Beta 3-glycosyltransferases

    1 InterPro protein domain:
     IPR002659 Glyco_trans_31

    Graphical View of Domain Structure for InterPro Entry Q9Y5Z6

    ProtoNet protein and cluster: Q9Y5Z6

    1 Blocks protein domain: IPB002659 Glycosyl transferase

    UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6
    Similarity: Belongs to the glycosyltransferase 31 family


    B3GALT1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B3GT1_HUMAN, Q9Y5Z6
    Function: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal
    beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of
    glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc)
    or alpha-N-acetylgalactosamine (alpha-GalNAc) residues

         Enzyme Numbers (IUBMB): EC 2.4.1.622 EC 2.4.12 EC 2.4.1.-1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008378galactosyltransferase activity ----
    GO:0008499UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity IDA9582303
         
    B3GALT1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for B3GALT1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for B3GALT1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for B3GALT1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for B3GALT1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat B3GALT1
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate B3GALT1:
    hsa-miR-182 hsa-miR-1255a hsa-miR-4330 hsa-miR-650 hsa-miR-3612 hsa-miR-548c-3p hsa-miR-1255b
    SwitchGear 3'UTR luciferase reporter plasmidB3GALT1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for B3GALT1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat B3GALT1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for B3GALT1
    Sirion Biotech Customized adenovirus for overexpression of B3GALT1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for B3GALT1 (see all 6)
    OriGene ORF clones in mouse, rat for B3GALT1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: B3GALT1 (NM_020981)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for B3GALT1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B3GALT1
    Sirion Biotech Customized lentivirus for stable overexpression of B3GALT1 
                         Customized lentivirus expression plasmids for stable overexpression of B3GALT1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for B3GALT1
    Search LifeMap BioReagents cell lines for B3GALT1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GALT1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for B3GALT1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolic pathways0.40
    2Glycosphingolipid biosynthesis - lacto and neolacto series
    Glycosphingolipid biosynthesis - lacto and neolacto series

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2         Kegg Pathways  (Kegg details for B3GALT1):
        Glycosphingolipid biosynthesis - lacto and neolacto series
    Metabolic pathways

    UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6
    Pathway: Protein modification; protein glycosylation


    B3GALT1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for B3GALT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/12 Interacting proteins for B3GALT1 (Q9Y5Z63 ENSP000003037404) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    UGT1A1P223093, ENSP000003048454I2D: score=1 STRING: ENSP00000304845
    TRAF6Q9Y4K33I2D: score=1 
    B4GALT1ENSP000003690554STRING: ENSP00000369055
    B4GALT3ENSP000003209654STRING: ENSP00000320965
    FUT2ENSP000003757484STRING: ENSP00000375748
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006486protein glycosylation IEA--
    GO:0009312oligosaccharide biosynthetic process IEA--
    GO:0030259lipid glycosylation NAS--

    B3GALT1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for B3GALT1 (B3GT1)

    1 HMDB Compound for B3GALT1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Manganesemanganese 7439-96-5--

    Search CenterWatch for drugs/clinical trials and news about B3GALT1 / B3GT1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for B3GALT1 gene: 
    NM_020981.3  

    Unigene Cluster for B3GALT1:

    UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
    Hs.735833  [show with all ESTs]
    Unigene Representative Sequence: NM_020981
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000392690(uc021vsc.1) ENST00000305861(uc002udz.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat B3GALT1
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate B3GALT1:
    hsa-miR-182 hsa-miR-1255a hsa-miR-4330 hsa-miR-650 hsa-miR-3612 hsa-miR-548c-3p hsa-miR-1255b
    SwitchGear 3'UTR luciferase reporter plasmidB3GALT1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for B3GALT1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat B3GALT1
    Clone
    Products:
         
    OriGene clones in human, mouse for B3GALT1 (see all 6)
    OriGene ORF clones in mouse, rat for B3GALT1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: B3GALT1 (NM_020981)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for B3GALT1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B3GALT1
    Sirion Biotech Customized lentivirus for stable overexpression of B3GALT1 
                         Customized lentivirus expression plasmids for stable overexpression of B3GALT1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for B3GALT1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat B3GALT1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat B3GALT1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat B3GALT1

    Additional mRNA sequence: 

    AF117222.1 BC101545.1 BC104813.1 

    1 DOTS entry:

    DT.92041619 

    6 AceView cDNA sequences:

    NM_020981 BX279676 AF117222 BG207694 AW196495 BV202899 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    B3GALT1 expression in normal human tissues (normalized intensities)      B3GALT1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    B3GALT1 Expression
    About this image


    B3GALT1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Medulla Oblongata
             brain/hindbrain   
     
     Gut Tube (Gastrointestinal Tract)
             Primitive gut tube-like cells ( A scalable, suspension protocol for derivation of...
     
     Inner Cell Mass (Early Embryonic Tissues)
             Line H9 (WA09)

     -- (Nervous System)
             mouse/organ system/nervous system/central nervous system   

    See B3GALT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for B3GALT1

    SOURCE GeneReport for Unigene cluster: Hs.735833

    UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6
    Tissue specificity: Detected in brain and colon mucosa and to a lesser extent in colon adenocarcinoma cells

        SABiosciences Custom PCR Arrays for B3GALT1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for B3GALT1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat B3GALT1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat B3GALT1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat B3GALT1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GALT1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for B3GALT1 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia B3galt11 , 5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, more1, 5 90.59(n)1
    100(a)1
      2 (39.53 cM)5
    268771  NM_020283.31  NP_064679.21 
     677482125 
    chicken
    (Gallus gallus)
    Aves B3GALT11 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, more 82.62(n)
    95.09(a)
      429027  XM_426584.3  XP_426584.1 
    lizard
    (Anolis carolinensis)
    Reptilia B3GALT16
    --
    --
    94(a)
    32(a)
    1 ↔ 1
    possible ortholog
    1(245835035-245836015)
    2(80622556-80623674)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.187422 Transcribed sequence with moderate similarity to protein more 74.4(n)    BQ616261.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta brn3
    CG331451
    glycosphingolipid biosynthesis
    acetylglucosaminyltransferase3
    CG331451
    33(a)
    (best of 2)3
    48.84(n)1
    39.18(a)1
      1 4A53
    362791  NM_176148.11  NP_788328.11 
    worm
    (Caenorhabditis elegans)
    Secernentea bus-176
    Protein BUS-17
    18(a)
    possible ortholog
    X(15757868-15766340)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons GALT11 beta-1,3-galactosyltransferase 15 44.72(n)
    31.28(a)
      839224  NM_102445.3  NP_174003.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g02292001 hypothetical protein 44.7(n)
    29.46(a)
      4340564  NM_001063748.1  NP_001057213.1 


    ENSEMBL Gene Tree for B3GALT1 (if available)
    TreeFam Gene Tree for B3GALT1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for B3GALT1 gene
    B3GNT32  B3GNT22  B3GNT52  B3GALT52  B3GNT42  B3GALT42  B3GALT22  B3GNT72  
    B3GNT82  B3GNT62  B3GALNT12  B3GNT92  
    12 SIMAP similar genes for B3GALT1 using alignment to 1 protein entry:     B3GT1_HUMAN:
    B3GALT2    OK/KNS-cl.1    B3GALNT1    B3GALT5    B3GNT2    B3GNT4
    B3GNT5    B3GNT6    B3GNT7    B3GNT8    B3GALT4    B3GNT3

    B3GALT1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1091 SNPs in B3GALT1 are shown (see all 1091)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs284903701,2
    C,F--168673246(+) ATTTTT/ACCAAT 1 -- us2k12Minor allele frequency- A:0.08CSA WA 120
    rs1927902081,2
    --168673267(+) AGTACA/GTGTTT 1 -- us2k10--------
    rs1155936321,2
    C,F--168673368(+) GGTTCA/CTGCAG 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1411678241,2
    --168673496(+) GATTGC/TTTCTG 1 -- us2k10--------
    rs1160936791,2
    F--168673601(+) CTTCAA/GTTGAA 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs752677621,2
    C,F--168673644(+) CAGCTG/CTCTAG 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs726231661,2
    C,F--168673805(+) TAATAC/TGTATA 1 -- us2k12Minor allele frequency- T:0.23NA EA 240
    rs730212281,2
    C,F--168673921(+) CATTTA/GTTTGA 1 -- us2k12Minor allele frequency- G:0.03WA 120
    rs1507159641,2
    --168673956(+) GGTACC/TGTCAT 1 -- us2k10--------
    rs8367171,2
    C,F,A,H--168673957(+) GTACCG/ATCATC 1 -- us2k123Minor allele frequency- A:0.33NS EA NA WA CSA 2548

    HapMap Linkage Disequilibrium report for B3GALT1 (168675182 - 168727366 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for B3GALT1: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing B3GALT1
    DNA2.0 Custom Variant and Variant Library Synthesis for B3GALT1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603093    OMIM disorders: --

    2 diseases for B3GALT1:    About MalaCards
    colon adenocarcinoma    adenocarcinoma


    B3GALT1 for disorders           About GeneDecksing


    Export disorders for B3GALT1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for B3GALT1 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with B3GALT1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta- nacetyl-galactosamine beta-1,3-galactosyltransferase family. (PubMed id 9582303)1, 2, 3, 9 Amado M.... Clausen H. (1998)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Differential expression of beta1,3galactosyltransferases in human colon cells derived from adenocarcinomas or normal mucosa. (PubMed id 10356986)1, 2 Bardoni A.... Trinchera M. (1999)
    5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    6. Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF M S for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein. (PubMed id 18565761)1 Irungu J....Desaire H. (2008)
    7. Human-specific amino acid changes found in 103 protein-coding genes. (PubMed id 15014171)2 Kitano T.... Saitou N. (2004)
    8. Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum. (PubMed id 12925779)1 Sprong H....van Meer G. (2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. (PubMed id 10580128)1 Amado M.... Clausen H. (1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8708 HGNC: 916 AceView: B3GALT1 Ensembl:ENSG00000172318 euGenes: HUgn8708
    ECgene: B3GALT1 Kegg: 8708 H-InvDB: B3GALT1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for B3GALT1 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GALT1
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_429

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for B3GALT1 gene:
    Search GeneIP for patents involving B3GALT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for B3GALT1  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for B3GALT1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for B3GALT1  
     OriGene qSTAR qPCR primer pairs in human, mouse for B3GALT1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for B3GALT1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for B3GALT1   OriGene Custom Protein Services for B3GALT1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat B3GALT1
     QIAGEN SeqTarget long-range PCR primers for resequencing B3GALT1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat B3GALT1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat B3GALT1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat B3GALT1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat B3GALT1
     GenScript Custom Purified and Recombinant Proteins Services for B3GALT1 GenScript cDNA clones with any tag delivered in your preferred vector for B3GALT1
     GenScript Custom Assay Services for B3GALT1 GenScript Custom Superior Antibodies Services for B3GALT1
     GenScript Custom overexpressing Cell Line Services for B3GALT1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in B3GALT1 promoter
     Search Chromatin IP Primers for B3GALT1
     RT2 qPCR Primer Assay in human, mouse, rat B3GALT1
     Search GNC Networks for B3GALT1
     SABiosciences Custom PCR Arrays for B3GALT1
     Search Tocris compounds for B3GALT1 (B3GT1)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     B3GALT1 antibodies
     B3GALT1 proteins
     B3GALT1 lysates
     Antibodies for B3GALT1
     See all of Abcam's Antibodies, Kits and Proteins for B3GALT1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for B3GALT1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for B3GALT1
     SwitchGear 3'UTR luciferase reporter plasmids for B3GALT1
     SwitchGear Promoter luciferase reporter plasmids for B3GALT1
     Search ThermoFisher Antibodies for B3GALT1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat B3GALT1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for B3GALT1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for B3GALT1
    Customized:
     lentivirus for stable overexpression of B3GALT1
     lentivirus expression plasmids for stable overexpression of B3GALT1
     adenovirus for overexpression of B3GALT1
     LSBio Antibodies in human, mouse, rat for B3GALT1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      B3GALT1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4