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B3GALT1 Gene

protein-coding   GIFtS: 48
GCID: GC02P168639

UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 11 2     beta3GalT12
Beta-1,3-GalTase 12 3     Beta3Gal-T13
UDP-Galactose:Beta-N-Acetyl-Glucosamine-Beta-1,3-Galactosyltransferase 12 3     Beta3GalT13
Beta-1,3-Galactosyltransferase 12     EC 2.4.1.-3
beta-3-galt12     EC 2.4.18
beta3Gal-T12     EC 2.4.1.628

External Ids:    HGNC: 9161   Entrez Gene: 87082   Ensembl: ENSG000001723187   OMIM: 6030935   UniProtKB: Q9Y5Z63   

Export aliases for B3GALT1 gene to outside databases

Previous GC identifers: GC02P166727 GC02P167216 GC02P168878 GC02P168879 GC02P168500 GC02P168383 GC02P160555


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for B3GALT1 Gene:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II
membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and
UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine).
The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence
contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or
alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas
beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during
embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other
beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is expressed exclusively in the brain. The encoded protein
shows strict donor substrate specificity for UDP-galactose. (provided by RefSeq, Jul 2008)

GeneCards Summary for B3GALT1 Gene:
B3GALT1 (UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1) is a protein-coding gene. GO annotations related to this gene include UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. An important paralog of this gene is B3GNT3.

UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6
Function: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal
beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of
glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc)
or alpha-N-acetylgalactosamine (alpha-GalNAc) residues




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the B3GALT1 gene promoter:
         c-Fos   AP-1   JunB   FosB   Fra-1   Roaz   JunD   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidB3GALT1 promoter sequence
   Search Chromatin IP Primers for B3GALT1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat B3GALT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24.3   Ensembl cytogenetic band:  2q24.3   HGNC cytogenetic band: 2q24.3

B3GALT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
B3GALT1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P168639:  view genomic region     (about GC identifiers)

Start:
168,675,182 bp from pter      End:
168,730,551 bp from pter
Size:
55,370 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6 (See protein sequence)
Recommended Name: Beta-1,3-galactosyltransferase 1  
Size: 326 amino acids; 37993 Da
Cofactor: Manganese (By similarity)
Secondary accessions: D3DPB8 Q53SS2

Explore the universe of human proteins at neXtProt for B3GALT1: NX_Q9Y5Z6

Explore proteomics data for B3GALT1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn47, Asn151
  • Modification sites at PhosphoSitePlus
  • 3 DME Specific Peptides for B3GALT1 (Q9Y5Z6)
     VMKTDSD  FCSGTGY  NLTLKTL 


    See B3GALT1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_066191.1  
    ENSEMBL proteins: 
     ENSP00000376456   ENSP00000303740  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    B3GT: Beta 3-glycosyltransferases

    1 InterPro protein domain:
     IPR002659 Glyco_trans_31

    Graphical View of Domain Structure for InterPro Entry Q9Y5Z6

    ProtoNet protein and cluster: Q9Y5Z6

    1 Blocks protein domain: IPB002659 Glycosyl transferase

    UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6
    Similarity: Belongs to the glycosyltransferase 31 family


    Find genes that share domains with B3GALT1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: B3GT1_HUMAN, Q9Y5Z6
    Function: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal
    beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of
    glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc)
    or alpha-N-acetylgalactosamine (alpha-GalNAc) residues

         Enzyme Numbers (IUBMB): EC 2.4.1.622 EC 2.4.12 EC 2.4.1.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008378galactosyltransferase activity ----
    GO:0008499UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity IDA9582303
         
    Find genes that share ontologies with B3GALT1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for B3GALT1

    miRNA
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    miRTarBase miRNAs that target B3GALT1:
    hsa-mir-26b-5p (MIRT029959)

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    SwitchGear 3'UTR luciferase reporter plasmidB3GALT1 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    B3GT1_HUMAN, Q9Y5Z6: Golgi apparatus membrane; Single-pass type II membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    cytosol1
    extracellular1
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral component of membrane NAS9582303

    Find genes that share ontologies with B3GALT1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for B3GALT1 About    
    See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolic pathways0.38
    2Glycosphingolipid biosynthesis - lacto and neolacto series
    Glycosphingolipid biosynthesis - lacto and neolacto series


    Find genes that share SuperPaths with B3GALT1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Kegg Pathways  (Kegg details for B3GALT1):
        Glycosphingolipid biosynthesis - lacto and neolacto series
    Metabolic pathways

    UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6
    Pathway: Protein modification; protein glycosylation

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for B3GALT1
    Interactions:

        Search GeneGlobe Interaction Network for B3GALT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for B3GALT1 (Q9Y5Z63 ENSP000003037404) via UniProtKB, MINT, STRING, and/or I2D (see all 15)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    UGT1A1P223093, ENSP000003048454I2D: score=1 STRING: ENSP00000304845
    TRAF6Q9Y4K33I2D: score=1 
    B4GALT1ENSP000003690554STRING: ENSP00000369055
    B4GALT3ENSP000003209654STRING: ENSP00000320965
    FUT2ENSP000003757484STRING: ENSP00000375748
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006486protein glycosylation IEA--
    GO:0009312oligosaccharide biosynthetic process IEA--
    GO:0030259lipid glycosylation ----

    Find genes that share ontologies with B3GALT1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for B3GALT1 (B3GT1)

    1 HMDB Compound for B3GALT1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Manganesemanganese 7439-96-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for B3GALT1 gene: 
    NM_020981.3  

    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000392690(uc021vsc.1) ENST00000305861(uc002udz.1)
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidB3GALT1 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat B3GALT1

    6 AceView cDNA sequences:

    BX279676 AF117222 NM_020981 BG207694 AW196495 BV202899 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    B3GALT1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    B3GALT1 Expression
    About this image


    B3GALT1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Epiblast (Early Embryonic Tissues)
             Epiblast-like cells
     
     Brain (Nervous System)
             Medulla Oblongata
    B3GALT1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    B3GALT1 Protein Expression

    UniProtKB/Swiss-Prot: B3GT1_HUMAN, Q9Y5Z6
    Tissue specificity: Detected in brain and colon mucosa and to a lesser extent in colon adenocarcinoma cells

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for B3GALT1 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia B3galt11 , 5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, more1, 5 90.59(n)1
    100(a)1
      2 (39.53 cM)5
    268771  NM_020283.41  NP_064679.21 
     677482125 
    chicken
    (Gallus gallus)
    Aves B3GALT11 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, more 82.62(n)
    95.09(a)
      429027  XM_004942778.1  XP_004942835.1 
    lizard
    (Anolis carolinensis)
    Reptilia B3GALT16
    UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase,...
    94(a)
    1 ↔ 1
    1(245835035-245836015)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia b3galt11 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, more 79.12(n)
    91.36(a)
      100488045  XM_004917705.1  XP_004917762.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.187422 Transcribed sequence with moderate similarity to protein more 74.4(n)    BQ616261.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta brn3
    CG86681
    glycosphingolipid biosynthesis
    acetylglucosaminyltransferase3
    CG86681
    33(a)
    (best of 2)3
    46.97(n)1
    34.71(a)1
      1 4A53
    341071  NM_135340.31  NP_609184.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G064401 AT3G06440 44.75(n)
    29.92(a)
      819820  NM_111519.2  NP_566284.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g03289001 Os01g0328900 44.09(n)
    32.66(a)
      4326981  NM_001049454.1  NP_001042919.1 


    ENSEMBL Gene Tree for B3GALT1 (if available)
    TreeFam Gene Tree for B3GALT1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for B3GALT1 gene
    B3GNT32  B3GNT22  B3GNT52  B3GALT52  B3GNT42  B3GALT42  B3GALT22  B3GNT72  
    B3GNT82  B3GNT62  B3GALNT12  B3GNT92  
    12 SIMAP similar genes for B3GALT1 using alignment to 1 protein entry:     B3GT1_HUMAN:
    B3GALT2    OK/KNS-cl.1    B3GALNT1    B3GALT5    B3GNT2    B3GNT4
    B3GNT5    B3GNT6    B3GNT7    B3GNT8    B3GALT4    B3GNT3

    Find genes that share paralogs with B3GALT1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for B3GALT1 (see all 1091)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs284903701,2
    C,F--168673246(+) ATTTTT/ACCAAT 1 -- us2k12Minor allele frequency- A:0.08CSA WA 120
    rs1927902081,2
    --168673267(+) AGTACA/GTGTTT 1 -- us2k10--------
    rs1155936321,2
    C,F--168673368(+) GGTTCA/CTGCAG 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1411678241,2
    --168673496(+) GATTGC/TTTCTG 1 -- us2k10--------
    rs1160936791,2
    F--168673601(+) CTTCAA/GTTGAA 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs752677621,2
    C,F--168673644(+) CAGCTG/CTCTAG 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs726231661,2
    C,F--168673805(+) TAATAC/TGTATA 1 -- us2k12Minor allele frequency- T:0.23NA EA 240
    rs730212281,2
    C,F--168673921(+) CATTTA/GTTTGA 1 -- us2k12Minor allele frequency- G:0.03WA 120
    rs1507159641,2
    --168673956(+) GGTACC/TGTCAT 1 -- us2k10--------
    rs8367171,2
    C,F,A,H--168673957(+) GTACCG/ATCATC 1 -- us2k123Minor allele frequency- A:0.33NS EA NA WA CSA 2548

    HapMap Linkage Disequilibrium report for B3GALT1 (168675182 - 168730551 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for B3GALT1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing B3GALT1
    DNA2.0 Custom Variant and Variant Library Synthesis for B3GALT1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603093    OMIM disorders: --


    Find genes that share disorders with B3GALT1           About GenesLikeMe


    Export disorders for B3GALT1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for B3GALT1 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with B3GALT1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta- nacetyl-galactosamine beta-1,3-galactosyltransferase family. (PubMed id 9582303)1, 2, 3, 9 Amado M.... Clausen H. (J. Biol. Chem. 1998)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Differential expression of beta1,3galactosyltransferases in human colon cells derived from adenocarcinomas or normal mucosa. (PubMed id 10356986)1, 2 Bardoni A.... Trinchera M. (FEBS Lett. 1999)
    5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    6. Comparison of HPLC/ESI-FTICR MS versus MALDI-TOF/TOF MS for glycopeptide analysis of a highly glycosylated HIV envelope glycoprotein. (PubMed id 18565761)1 Irungu J....Desaire H. (J. Am. Soc. Mass Spectrom. 2008)
    7. Human-specific amino acid changes found in 103 protein-coding genes. (PubMed id 15014171)2 Kitano T.... Saitou N. (Mol. Biol. Evol. 2004)
    8. Association of the Golgi UDP-galactose transporter with UDP-galactose:ceramide galactosyltransferase allows UDP-galactose import in the endoplasmic reticulum. (PubMed id 12925779)1 Sprong H....van Meer G. (Mol. Biol. Cell 2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. (PubMed id 10580128)1 Amado M.... Clausen H. (Biochim. Biophys. Acta 1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8708 HGNC: 916 AceView: B3GALT1 Ensembl:ENSG00000172318 euGenes: HUgn8708
    ECgene: B3GALT1 Kegg: 8708 H-InvDB: B3GALT1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for B3GALT1 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=B3GALT1
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_429

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for B3GALT1 gene:
    Search GeneIP for patents involving B3GALT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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