Aliases for B2M Gene
External Ids for B2M Gene
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
GeneCards Summary for B2M Gene
B2M (Beta-2-Microglobulin) is a Protein Coding gene. Diseases associated with B2M include complication in hemodialysis and balkan nephropathy. Among its related pathways are Signaling by FGFR and Signaling by FGFR. GO annotations related to this gene include identical protein binding.
UniProtKB/Swiss-Prot for B2M Gene
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system