Aliases for ATP5L Gene
- ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit G 2 3 5
- ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subunit G 2 3
- ATPase Subunit G 3 4
- ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit G 2
- ATP Synthase, H+ Transporting, Mitochondrial F1F0, Subunit G 3
- F1Fo-ATP Synthase Complex Fo Membrane Domain G Subunit 3
External Ids for ATP5L Gene
Previous GeneCards Identifiers for ATP5L Gene
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the g subunit of the Fo complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
GeneCards Summary for ATP5L Gene
ATP5L (ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit G) is a Protein Coding gene. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and purine nucleotides de novo biosynthesis. GO annotations related to this gene include ATPase activity and hydrogen ion transmembrane transporter activity. An important paralog of this gene is ATP5L2.
UniProtKB/Swiss-Prot for ATP5L Gene
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.