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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AZIN1 Gene

protein-coding   GIFtS: 58
GCID: GC08M103838

Antizyme Inhibitor 1

(Previous name: ornithine decarboxylase antizyme inhibitor)
(Previous symbol: OAZIN)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Antizyme Inhibitor 11 2     OAZI2 3
OAZIN1 2 3 5     Ornithine Decarboxylase 1-Like1
Ornithine Decarboxylase Antizyme Inhibitor1 2 3     ODC1L2
AZI2 3     EC 4.1.1.178

External Ids:    HGNC: 164321   Entrez Gene: 515822   Ensembl: ENSG000001550967   OMIM: 6079095   UniProtKB: O149773   

Export aliases for AZIN1 gene to outside databases

Previous GC identifers: GC00U921561 GC08M103908 GC08M099039


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AZIN1 Gene:
Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently
rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of
polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is
highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC
degradation. Two alternatively spliced transcript variants have been found for this gene. (provided by RefSeq,
Jul 2008)

GeneCards Summary for AZIN1 Gene: 
AZIN1 (antizyme inhibitor 1) is a protein-coding gene. Diseases associated with AZIN1 include fanconi's anemia, and liver cirrhosis, and among its related super-pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Metabolic pathways. GO annotations related to this gene include ornithine decarboxylase activator activity and catalytic activity. An important paralog of this gene is ODC1.

UniProtKB/Swiss-Prot: AZIN1_HUMAN, O14977
Function: Regulates cellular polyamine homeostasis (By similarity). Inhibits antizyme-dependent ornithine
decarboxylase degradation by binding to antizyme

Gene Wiki entry for AZIN1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NT_008046.16  NC_018919.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AZIN1 gene promoter:
         E2F-4   E2F-3a   E2F-5   AML1a   p300   E2F-2   MZF-1   E2F   E2F-1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAZIN1 promoter sequence
   Search SABiosciences Chromatin IP Primers for AZIN1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AZIN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.3   Ensembl cytogenetic band:  8q22.3   HGNC cytogenetic band: 8p22-q21.3

AZIN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AZIN1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M103838:  view genomic region     (about GC identifiers)

Start:
103,838,536 bp from pter      End:
103,906,092 bp from pter
Size:
67,557 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AZIN1_HUMAN, O14977 (See protein sequence)
Recommended Name: Antizyme inhibitor 1  
Size: 448 amino acids; 49535 Da
Subunit: Monomer (By similarity)
Secondary accessions: A6NCD5 Q6IBQ7 Q96D20

Explore the universe of human proteins at neXtProt for AZIN1: NX_O14977

Explore proteomics data for AZIN1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O14977

  • 3 DME Specific Peptides for AZIN1 (O14977)
     LDIGGGF  SQIKYAA  SDARCVFDM 

    AZIN1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AZIN1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_056962.2  NP_680479.1  

    ENSEMBL proteins: 
     ENSP00000337180   ENSP00000321507   ENSP00000475919   ENSP00000429449   ENSP00000429215  
    Reactome Protein details: O14977
    Human Recombinant Protein Products for AZIN1: 
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    Novus Biologicals AZIN1 Proteins
    Novus Biologicals AZIN1 Lysates
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    Cloud-Clone Corp. Proteins for AZIN1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--

    AZIN1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for AZIN1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR009006 Ala_racemase/Decarboxylase_C
     IPR002433 Orn_de-COase
     IPR000183 Orn/DAP/Arg_de-COase
     IPR022644 De-COase2_N
     IPR022643 De-COase2_C

    Graphical View of Domain Structure for InterPro Entry O14977

    ProtoNet protein and cluster: O14977

    2 Blocks protein domains:
    IPB000183 Orn/DAP/Arg decarboxylase
    IPB002433 Ornithine decarboxylase signature


    UniProtKB/Swiss-Prot: AZIN1_HUMAN, O14977
    Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC antizyme inhibitor subfamily


    AZIN1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AZIN1_HUMAN, O14977
    Function: Regulates cellular polyamine homeostasis (By similarity). Inhibits antizyme-dependent ornithine
    decarboxylase degradation by binding to antizyme

         Enzyme Number (IUBMB): EC 4.1.1.172

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity IEA--
    GO:0004857enzyme inhibitor activity TAS9349715
    GO:0042978ornithine decarboxylase activator activity IEA--
         
    AZIN1 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Azin1):
     growth/size  liver/biliary system  mortality/aging 

    AZIN1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for AZIN1 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AZIN1 
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    miRNA
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    8/65 QIAGEN miScript miRNA Assays for microRNAs that regulate AZIN1 (see all 65):
    hsa-miR-411* hsa-miR-300 hsa-miR-485-3p hsa-miR-30d hsa-miR-138-2* hsa-miR-30a hsa-miR-4293 hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidAZIN1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for AZIN1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1CDK-mediated phosphorylation and removal of Cdc6
    Regulation of ornithine decarboxylase (ODC)0.80
    2Metabolism
    Metabolism0.40
    3Metabolism of amino acids and derivatives
    Metabolism of amino acids and derivatives
    4Diurnally regulated genes with circadian orthologs
    Diurnally regulated genes with circadian orthologs

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for AZIN1
        Diurnally regulated genes with circadian orthologs


    3        Reactome Pathways for AZIN1
        Regulation of ornithine decarboxylase (ODC)
    Metabolism
    Metabolism of amino acids and derivatives



    AZIN1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AZIN1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/13 Interacting proteins for AZIN1 (O149771, 3 ENSP000003215074) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    OAZ2O951901, 3EBI-1054824,EBI-1051861 I2D: score=2 
    FANCAO153603, ENSP000003739524I2D: score=1 STRING: ENSP00000373952
    FANCCQ005973, ENSP000002890814I2D: score=1 STRING: ENSP00000289081
    OAZ1ENSP000003148134STRING: ENSP00000314813
    OAZ3ENSP000003139224STRING: ENSP00000313922
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006521regulation of cellular amino acid metabolic process TAS--
    GO:0006596polyamine biosynthetic process IEA--
    GO:0034641cellular nitrogen compound metabolic process TAS--
    GO:0043086negative regulation of catalytic activity TAS9349715
    GO:0044281small molecule metabolic process TAS--

    AZIN1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AZIN1

    1 HMDB Compound for AZIN1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Ornithine(+)-S-Ornithine (see all 9)70-26-8--

    Search CenterWatch for drugs/clinical trials and news about AZIN1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AZIN1 gene (2 alternative transcripts): 
    NM_015878.4  NM_148174.2  

    Unigene Cluster for AZIN1:

    Antizyme inhibitor 1
    Hs.459106  [show with all ESTs]
    Unigene Representative Sequence: NM_015878
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000337198(uc003ykx.3 uc003yky.3) ENST00000347770 ENST00000518697
    ENST00000523071 ENST00000521536 ENST00000522311 ENST00000520402 ENST00000518353
    ENST00000518940 ENST00000517581
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/65 QIAGEN miScript miRNA Assays for microRNAs that regulate AZIN1 (see all 65):
    hsa-miR-411* hsa-miR-300 hsa-miR-485-3p hsa-miR-30d hsa-miR-138-2* hsa-miR-30a hsa-miR-4293 hsa-miR-92b
    SwitchGear 3'UTR luciferase reporter plasmidAZIN1 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AZIN1
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    Additional mRNA sequence: 

    AF070634.1 AK095493.1 AK290516.1 BC013420.2 BC019279.1 BC042404.1 BT006858.1 CR456745.1 
    D88674.1 

    24/36 DOTS entries (see all 36):

    DT.92463728  DT.100878296  DT.120631357  DT.95271065  DT.95271063  DT.120631377  DT.100762135  DT.92416836 
    DT.40117039  DT.100840249  DT.100774130  DT.120631284  DT.120631366  DT.120631517  DT.120631301  DT.95271068 
    DT.100743868  DT.120631306  DT.92463743  DT.95190460  DT.120631511  DT.120631551  DT.120631278  DT.120631344 

    24/674 AceView cDNA sequences (see all 674):

    AW470173 BX354392 CD676048 CK819930 AA873001 BU430888 BM773216 BE740079 
    AI082285 CB150653 AA827593 AW169521 CD653615 AI436062 BC013420 BQ924192 
    BU521432 CB305787 AA775534 AA165122 CA440492 AA598714 BG622568 AW150615 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for AZIN1 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^
    SP1:                    -                       -                                                     -                                   -                     
    SP2:                    -                       -     -                                               -                                   -                     
    SP3:                                                                                                  -                                   -                     
    SP4:                                                                                                                                      -                     
    SP5:                                            -     -                       -     -                 -                                                         

    ExUns: 15a · 15b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for AZIN1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AZIN1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTTTCACCC
    AZIN1 Expression
    About this image


    See AZIN1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AZIN1

    SOURCE GeneReport for Unigene cluster: Hs.459106

    UniProtKB/Swiss-Prot: AZIN1_HUMAN, O14977
    Tissue specificity: Expressed in liver

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for AZIN1 gene from 8/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Azin11 , 5 antizyme inhibitor 11, 5 93.53(n)1
    95.76(a)1
      15 (15.17 cM)5
    543751  NM_018745.51  NP_061215.11 
     384874305 
    chicken
    (Gallus gallus)
    Aves AZIN11 antizyme inhibitor 1 81.77(n)
    77.68(a)
      420254  NM_001008729.1  NP_001008729.1 
    lizard
    (Anolis carolinensis)
    Reptilia AZIN16
    Uncharacterized protein
    76(a)
    1 ↔ 1
    4(13827205-13859491)
    African clawed frog
    (Xenopus laevis)
    Amphibia CA790747.12   -- 81.4(n)    CA790747.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC061960.12   -- 77.56(n)   317764  BC061960.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Odc16
    Odc26
    Ornithine decarboxylase 2
    37(a)
    36(a)
    possible ortholog
    possible ortholog
    2R(3892308-3894177)
    2R(3894769-3896567)
    worm
    (Caenorhabditis elegans)
    Secernentea odc-16
    F53F10.26
    Protein F53F10.2, isoform a
    34(a)
    20(a)
    possible ortholog
    many → 1
    V(6898541-6900223)
    I(3831117-3834124)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SPE16
    Ornithine decarboxylase, catalyzes the first step ...
    32(a)
    1 → many
    XI(96757-98157)


    ENSEMBL Gene Tree for AZIN1 (if available)
    TreeFam Gene Tree for AZIN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AZIN1 gene
    ODC12  ADC2  
    2 SIMAP similar genes for AZIN1 using alignment to 3 protein entries:     AZIN1_HUMAN (see all proteins):
    ODC1    ADC

    AZIN1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/756 SNPs in AZIN1 are shown (see all 756)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs737015301,2
    C,F--103838055(+) TACTAG/ATGCAT 2 -- ds50012Minor allele frequency- A:0.10WA 120
    rs777153971,2
    F--103838130(+) TAACTA/GAAGTG 2 -- ds50011Minor allele frequency- G:0.03WA 118
    rs1853945141,2
    --103838387(+) GAACTG/TAAGTG 2 -- ds50010--------
    rs1456880931,2
    --103838464(+) CTATAC/TATAAC 2 -- ds50010--------
    rs10623651,2
    C--103838674(-) AAATAC/TAAAAC 2 -- ut310--------
    rs1403341501,2
    C--103838677(+) TTATAA/TTTGCA 2 -- ut310--------
    rs1380471411,2
    C--103838848(+) TCACAC/TGTGAT 2 -- ut310--------
    rs32034441,2
    C,F--103838872(-) AAGAAA/GTAGCT 2 -- ut311Minor allele frequency- G:0.00MN 184
    rs69211,2
    C,F,A--103838876(+) ATTTCT/ATATAG 2 -- ut31 ese312Minor allele frequency- A:0.47MN NA WA CSA EA 557
    rs1906428691,2
    --103838884(+) TAGAAC/TAGCTC 2 -- ut310--------

    HapMap Linkage Disequilibrium report for AZIN1 (103838536 - 103906092 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for AZIN1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv33118CNV Loss17666407
    nsv891245CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607909    OMIM disorders: --

    9 diseases for AZIN1:    About MalaCards
    fanconi's anemia    liver cirrhosis    anemia    hepatitis c
    hepatitis    hepatitis b    pneumonia    prostate cancer
    prostatitis


    AZIN1 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: AZIN1 (1 document)

    Export disorders for AZIN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AZIN1 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with AZIN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor. (PubMed id 9349715)1, 2, 3 Koguchi K....Hayashi S. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 3 Yu W.... Gibbs R.A. (1997)
    4. Recoding RNA editing of AZIN1 predisposes to hepatocel lular carcinoma. (PubMed id 23291631)1 Chen L....Guan X.Y. (2013)
    5. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    6. [Polymorphism of ornithine decarboxylase antizyme inh ibitor 1 gene is associated with liver cirrhosis in Chinese hepatitis B patient s]. (PubMed id 21586232)1 Peng L.J....Wang J.Y. (2011)
    7. Minimal antizyme peptide fully functioning in the bin ding and inhibition of ornithine decarboxylase and antizyme inhibitor. (PubMed id 21931692)1 Hsieh J.Y....Hung H.C. (2011)
    8. A polymorphism that delays fibrosis in hepatitis C pr omotes alternative splicing of AZIN1, reducing fibrogenesis. (PubMed id 21837750)1 Paris A.J....Friedman S.L. (2011)
    9. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51582 HGNC: 16432 AceView: OAZIN Ensembl:ENSG00000155096 euGenes: HUgn51582
    ECgene: AZIN1 H-InvDB: AZIN1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AZIN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AZIN1 gene:
    Search GeneIP for patents involving AZIN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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