Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AZI1 Gene

protein-coding   GIFtS: 54
GCID: GC17M079163

5-Azacytidine Induced 1

  Search for AZI1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
5-Azacytidine Induced 11 2     KIAA11183 5
Centrosomal Protein Of 131 KDa2 3     5-Azacytidine-Induced Protein 12
Pre-Acrosome Localization Protein 12 3     AZ12
Cep1312 3     Centrosomal Protein 131 KDa2
ZA12 5     CEP1313

External Ids:    HGNC: 295111   Entrez Gene: 229942   Ensembl: ENSG000001415777   OMIM: 6134795   UniProtKB: Q9UPN43   

Export aliases for AZI1 gene to outside databases

Previous GC identifers: GC17M079725 GC17M079863 GC17M076777 GC17M074602


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for AZI1 Gene: 
AZI1 (5-azacytidine induced 1) is a protein-coding gene. Among its related super-pathways are G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include molecular_function.

UniProtKB/Swiss-Prot: AZI1_HUMAN, Q9UPN4
Function: May play a role in spermatogenesis (By similarity)

Gene Wiki entry for AZI1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AZI1 gene promoter:
         ISGF-3   C/EBPbeta   Sp1   p53   LCR-F1   HEN1   Pax-3   ARP-1   Pax-4a   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAZI1 promoter sequence
   Search SABiosciences Chromatin IP Primers for AZI1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AZI1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.3   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25.3

AZI1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AZI1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M079163:  view genomic region     (about GC identifiers)

Start:
79,163,393 bp from pter      End:
79,196,799 bp from pter
Size:
33,407 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AZI1_HUMAN, Q9UPN4 (See protein sequence)
Recommended Name: 5-azacytidine-induced protein 1  
Size: 1083 amino acids; 122149 Da
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Sequence caution: Sequence=BAA83070.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NHI8 B2RN11 Q96F50
Alternative splicing: 3 isoforms:  Q9UPN4-1   Q9UPN4-2   Q9UPN4-3   (Contains a phosphoserine at position 489. Contains a phosphoserine at position 496)

Explore the universe of human proteins at neXtProt for AZI1: NX_Q9UPN4

Explore proteomics data for AZI1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UPN4

  • AZI1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AZI1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001009811.2  NP_055799.2  

    ENSEMBL proteins: 
     ENSP00000363914   ENSP00000269392   ENSP00000461374   ENSP00000460006   ENSP00000393583  
     ENSP00000459733   ENSP00000460098  
    Reactome Protein details: Q9UPN4
    Human Recombinant Protein Products for AZI1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for AZI1
    GenScript Custom Purified and Recombinant Proteins Services for AZI1
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for AZI1 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005813colocalizes with centrosome IDA14654843
    GO:0005829cytosol TAS--
    GO:0015630microtubule cytoskeleton IDA--
    GO:0016020membrane ----
    GO:0043231intracellular membrane-bounded organelle IDA--

    AZI1 for ontologies           About GeneDecksing



    AZI1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for AZI1
    GenScript Custom Superior Antibodies Services for AZI1
    Novus Biologicals AZI1 Antibodies
    Abcam antibodies for AZI1
    Cloud-Clone Corp. Antibodies for AZI1 
    ThermoFisher Antibodies for AZI1
    LSBio Antibodies in human, mouse, rat for AZI1 

    Assay Products for AZI1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for AZI1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for AZI1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for AZI1 
    Cloud-Clone Corp. CLIAs for AZI1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q9UPN4

    UniProtKB/Swiss-Prot: AZI1_HUMAN, Q9UPN4
    Similarity: Contains 1 IQ domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AZI1_HUMAN, Q9UPN4
    Function: May play a role in spermatogenesis (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    AZI1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for AZI1:
     Increased cell number in S and  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for AZI1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AZI1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AZI1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for AZI1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AZI1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate AZI1
    SwitchGear 3'UTR luciferase reporter plasmidAZI1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for AZI1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AZI1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for AZI1
    Sirion Biotech Customized adenovirus for overexpression of AZI1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for AZI1 (see all 9)
    OriGene ORF clones in mouse, rat for AZI1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): AZI1 (NM_014984)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for AZI1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AZI1
    Sirion Biotech Customized lentivirus for stable overexpression of AZI1 
                         Customized lentivirus expression plasmids for stable overexpression of AZI1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for AZI1
    Search LifeMap BioReagents cell lines for AZI1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AZI1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for AZI1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Recruitment of mitotic centrosome proteins and complexes
    Recruitment of mitotic centrosome proteins and complexes0.83
    Mitotic G2-G2/M phases0.81
    Centrosome maturation0.83
    Loss of Nlp from mitotic centrosomes0.78
    G2/M Transition0.83
    Loss of proteins required for interphase microtubule organization,from the centrosome0.78
    2Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/8        Reactome Pathways for AZI1 (see all 8)
        Centrosome maturation
    Cell Cycle
    Recruitment of mitotic centrosome proteins and complexes
    G2/M Transition
    Loss of proteins required for interphase microtubule organization,from the centrosome



    AZI1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for AZI1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/61 Interacting proteins for AZI1 (Q9UPN43 ENSP000003935834) via UniProtKB, MINT, STRING, and/or I2D (see all 61)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    OAZ1P543683, ENSP000003148134I2D: score=1 STRING: ENSP00000314813
    TP73O153503, ENSP000003675454I2D: score=1 STRING: ENSP00000367545
    YWHAEP622583, ENSP000002643354I2D: score=1 STRING: ENSP00000264335
    ODC1P119263, ENSP000002341114I2D: score=1 STRING: ENSP00000234111
    POT1Q9NUX53, ENSP000003502494I2D: score=1 STRING: ENSP00000350249
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000086G2/M transition of mitotic cell cycle TAS--
    GO:0000278mitotic cell cycle TAS--
    GO:0007275multicellular organismal development IEA--
    GO:0007283spermatogenesis IEA--
    GO:0008150biological_process ND--

    AZI1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AZI1

    Search CenterWatch for drugs/clinical trials and news about AZI1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AZI1 gene (2 alternative transcripts): 
    NM_001009811.2  NM_014984.2  

    Unigene Cluster for AZI1:

    5-azacytidine induced 1
    Hs.514578  [show with all ESTs]
    Unigene Representative Sequence: BC012130
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374782 ENST00000269392(uc002jzm.1 uc002jzn.1 uc002jzo.1 uc002jzp.1 uc010wum.1)
    ENST00000570817 ENST00000573053(uc002jzq.3) ENST00000450824 ENST00000575907
    ENST00000571292 ENST00000570482
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AZI1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate AZI1
    SwitchGear 3'UTR luciferase reporter plasmidAZI1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for AZI1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AZI1
    Clone
    Products:
         
    OriGene clones in human, mouse for AZI1 (see all 9)
    OriGene ORF clones in mouse, rat for AZI1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): AZI1 (NM_014984)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for AZI1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AZI1
    Sirion Biotech Customized lentivirus for stable overexpression of AZI1 
                         Customized lentivirus expression plasmids for stable overexpression of AZI1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for AZI1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AZI1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AZI1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AZI1

    Additional mRNA sequence: 

    AB029041.1 BC010413.2 BC011615.2 BC012130.1 BC040023.1 BC136578.1 BC136580.1 BC144263.1 

    6 DOTS entries:

    DT.70104946  DT.92424048  DT.100697986  DT.435887  DT.100802481  DT.92049878 

    24/65 AceView cDNA sequences (see all 65):

    BU165495 BE384437 BC010413 BQ069739 BE734213 BC040023 BE902597 BM911459 
    BQ637523 BM927610 CO250199 BG109696 AL135248 AI817702 BG397349 CF125276 
    BQ427802 BM929526 BF591342 AB029041 BX391524 BQ055144 BM696646 BF974651 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for AZI1 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19a · 19b ^ 20 ^ 21 ^ 22a · 22b ^
    SP1:                                -                                                                                                                           
    SP2:                                                                                -                                                                           
    SP3:                                                                                                                                      -                     
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                      -                     

    ExUns: 23a · 23b · 23c ^ 24a · 24b ^ 25 ^ 26 ^ 27
    SP1:  -                                             
    SP2:  -                                             
    SP3:  -                                             
    SP4:                                                
    SP5:                                                


    ECgene alternative splicing isoforms for AZI1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AZI1 expression in normal human tissues (normalized intensities)      AZI1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGCTGCGGT
    AZI1 Expression
    About this image


    AZI1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)
             ES-J1

    See AZI1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AZI1

    SOURCE GeneReport for Unigene cluster: Hs.514578
        SABiosciences Custom PCR Arrays for AZI1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for AZI1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AZI1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AZI1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AZI1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AZI1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for AZI1 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Azi11 , 5 5-azacytidine induced gene 11, 5 78.97(n)1
    74.69(a)1
      11 (83.96 cM)5
    120091  NM_009734.31  NP_033864.31 
     1200644305 
    chicken
    (Gallus gallus)
    Aves AZI11 5-azacytidine induced 1 70.36(n)
    62.65(a)
      422074  XM_420077.3  XP_420077.3 
    lizard
    (Anolis carolinensis)
    Reptilia AZI16
    5-azacytidine induced 1
    58(a)
    1 ↔ 1
    2(99340845-99380172)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.253952 Xenopus laevis transcribed sequence with weak similarity more 73.44(n)    BJ058775.1 
    zebrafish
    (Danio rerio)
    Actinopterygii azi11 5-azacytidine induced gene 1 58.83(n)
    52.96(a)
      563066  XM_002664004.1  XP_002664050.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta dila6
    dilatory
    18(a)
    1 ↔ 1
    2R(5710582-5714988)


    ENSEMBL Gene Tree for AZI1 (if available)
    TreeFam Gene Tree for AZI1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1196 SNPs in AZI1 are shown (see all 1196)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1877428891,2
    --74635095(+) ATTGTC/GAGGGA 2 -- us2k10--------
    rs1471068241,2
    C--74635104(+) GATTGA/GTTTTA 2 -- us2k10--------
    rs785825561,2
    C,F--79162898(+) GAGAGC/TTCCAG 2 -- int12Minor allele frequency- T:0.11CSA WA 120
    rs1822805661,2
    --79162918(+) CCTTGA/GCAGCG 2 -- int10--------
    rs1148764371,2
    C,F--79163210(+) CTGGGG/AGCTGC 2 -- int11Minor allele frequency- A:0.02WA 118
    rs754664971,2
    C--79163320(+) AGCCAA/GACCCA 2 -- int13Minor allele frequency- G:0.05NA EA 242
    rs1995238521,2
    C--79163372(+) GAGAG-/AAGACAA 2 -- int10--------
    rs1472613221,2
    C--79163406(+) AACAAC/TGGCCT 2 -- ut310--------
    rs1487547361,2
    --79163481(+) GGGGGC/TAGGTG 2 -- ut310--------
    rs1154348291,2
    C,F--79163514(+) CCCACG/ATCCAG 2 -- ut311Minor allele frequency- A:0.02WA 118

    HapMap Linkage Disequilibrium report for AZI1 (79163393 - 79196799 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/34 variations for AZI1 (see all 34):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2716439CNV Deletion23290073
    esv2716435CNV Deletion23290073
    esv1376421CNV Deletion17803354
    dgv474e201CNV Deletion23290073
    dgv475e201CNV Deletion23290073
    esv2716442CNV Deletion23290073
    esv995211CNV Deletion20482838
    esv2672358CNV Deletion23128226
    esv1728201CNV Insertion17803354
    esv1160595CNV Insertion17803354

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing AZI1
    DNA2.0 Custom Variant and Variant Library Synthesis for AZI1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AZI1 for disorders           About MalaCards
    OMIM gene information: 613479    OMIM disorders: --


    AZI1 for disorders           About GeneDecksing


    Export disorders for AZI1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AZI1 gene, integrated from 9 sources (see all 38):
    (articles sorted by number of sources associating them with AZI1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Proteomic characterization of the human centrosome by protein correlation profiling. (PubMed id 14654843)1, 2, 3 Andersen J.S....Mann M. (2003)
    2. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2, 3 Kikuno R....Ohara O. (1999)
    3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Genomic organization of the mouse AZ1 gene that encodes the protein localized to preacrosomes of spermatids. (PubMed id 9070930)1, 3 Aoto H....Tajima S. (1997)
    7. ODCp, a brain- and testis-specific ornithine decarboxylase paralogue, functions as an antizyme inhibitor, although less efficiently than AzI1. (PubMed id 18062773)1, 9 Snapir Z....Kahana C. (2008)
    8. Loci associated with N-glycosylation of human immunogl obulin G show pleiotropy with autoimmune diseases and haematological cancers. (PubMed id 23382691)1 Lauc G....Rudan I. (2013)
    9. Regulation of CEP131 gene expression by SP1. (PubMed id 23137637)1 Huong P.T....Kim B.Y. (2013)
    10. The centriolar satellite protein Cep131 is important f or genome stability. (PubMed id 22797915)1 Staples C.J....Collis S.J. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 22994 HGNC: 29511 AceView: AZI1 Ensembl:ENSG00000141577 euGenes: HUgn22994
    ECgene: AZI1 H-InvDB: AZI1

    (According to HUGE)
    About This Section
    HUGE: KIAA1118

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AZI1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AZI1 gene:
    Search GeneIP for patents involving AZI1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for AZI1  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for AZI1  
     OriGene qSTAR qPCR primer pairs in human, mouse for AZI1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for AZI1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for AZI1   OriGene Custom Protein Services for AZI1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AZI1
     QIAGEN SeqTarget long-range PCR primers for resequencing AZI1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AZI1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AZI1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AZI1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AZI1
     GenScript Custom Purified and Recombinant Proteins Services for AZI1 GenScript cDNA clones with any tag delivered in your preferred vector for AZI1
     GenScript Custom Assay Services for AZI1 GenScript Custom Superior Antibodies Services for AZI1
     GenScript Custom overexpressing Cell Line Services for AZI1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in AZI1 promoter
     Search Chromatin IP Primers for AZI1
     RT2 qPCR Primer Assay in human, mouse, rat AZI1
     GNC Network for AZI1
     SABiosciences Custom PCR Arrays for AZI1
     Search Tocris compounds for AZI1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     AZI1 antibodies
     Antibodies for AZI1
     See all of Abcam's Antibodies, Kits and Proteins for AZI1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for AZI1
     Antibodies for AZI1
     ELISAs for AZI1
     CLIAs for AZI1
     Search LifeMap BioReagents cell lines for AZI1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AZI1
     SwitchGear 3'UTR luciferase reporter plasmids for AZI1
     SwitchGear Promoter luciferase reporter plasmids for AZI1
     ThermoFisher Antibodies for AZI1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AZI1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for AZI1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AZI1
    Customized:
     lentivirus for stable overexpression of AZI1
     lentivirus expression plasmids for stable overexpression of AZI1
     adenovirus for overexpression of AZI1
     LSBio Antibodies in human, mouse, rat for AZI1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      AZI1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4