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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AZGP1 Gene

protein-coding   GIFtS: 55
GCID: GC07M099564

alpha-2-glycoprotein 1, zinc-binding

(Previous names: alpha-2-glycoprotein 1, zinc )
 Explore 26 diseases affiliated with
AZGP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for AZGP1    

Aliases
for AZGP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Alpha-2-Glycoprotein 1, Zinc-Binding1 2     Zinc-Alpha-2-Glycoprotein1
ZAG1 2 3 5     Zn-Alpha-2-GP1
ZA2G1 2     Zn-Alpha-2-Glycoprotein1
Alpha-2-Glycoprotein 1, Zinc1     ZNGP13
Zn-Alpha2-Glycoprotein1     Zn-Alpha-2-GP1
Alpha-2-Glycoprotein, Zinc2     Zn-Alpha-2-Glycoprotein1

External Ids:    HGNC: 9101   Entrez Gene: 5632   Ensembl: ENSG000001608627   OMIM: 1944605   UniProtKB: P253113   

Export aliases for AZGP1 gene to outside databases

Previous GC identifers: GC07M098099 GC07M099161 GC07M099175 GC07M099209 GC07M099402 GC07M094200


Summaries
for AZGP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: ZA2G_HUMAN, P25311
Function: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced
cancers. May bind polyunsaturated fatty acids

Gene Wiki entry for AZGP1


Genomic Views
for AZGP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AZGP1 gene promoter:
         Max1   NF-1   Elk-1   NCX/Ncx   PPAR-gamma1   POU2F1   POU2F1a   PPAR-gamma2   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: AZGP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for AZGP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AZGP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22.1

AZGP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AZGP1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M099564:  view genomic region     (about GC identifiers)

Start:
 99,564,343 bp from pter      End:
 99,573,780 bp from pter
Size:
 9,438 bases      Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 98,924,486-98,933,868     

Proteins
for AZGP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ZA2G_HUMAN, P25311 (See protein sequence)
Recommended Name: Zinc-alpha-2-glycoprotein precursor  
Size: 298 amino acids; 34259 Da
Subunit: Interacts with PIP
Subcellular location: Secreted
Caution: It is uncertain whether Met-1 or Met-4 is the initiator
Sequence caution: Sequence=AAA61311.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAA03123.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA14417.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAA42438.1; Type=Erroneous initiation;
Note=Translation N-terminally extended;
6/8 PDB 3D structures from and Proteopedia for AZGP1 (see all 8):
1T7V (3D)        1T7W (3D)        1T7X (3D)        1T7Y (3D)        1T7Z (3D)        1T80 (3D)    
Secondary accessions: D6W5T8 O60386 Q5XKQ4 Q8N4N0

Explore the universe of human proteins at neXtProt for AZGP1: NX_P25311

Post-translational modifications:

  • N-glycosylated. N-glycan at Asn-128: Hex5HexNAc41
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P25311

    • AZGP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001176.1  
    ENSEMBL proteins: 
     ENSP00000292401   ENSP00000389942   ENSP00000396093  

    Human Recombinant Protein Products: 
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    R&D Systems Recombinant & Natural Proteins for AZGP1 (ZAG)
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    OriGene Protein Over-expression Lysate: AZGP1
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    Novus Biologicals AZGP1 Proteins
    Novus Biologicals AZGP1 Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for AZGP1
    Browse Proteins at Uscn

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region NAS14718574
    GO:0042612MHC class I protein complex IEA--


    AZGP1 for ontologies           About GeneDecksing



    AZGP1 Antibody Products: 
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    ThermoFisher Antibodies for AZGP1

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    Browse ELISAs and CLIAs at Uscn

    Protein Domains /
    Families
    for AZGP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    AZGP1 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR007110 Ig-like_dom
     IPR003006 Ig/MHC_CS
     IPR011161 MHC_I-like_Ag-recog
     IPR001039 MHC_I_a_a1/a2
     IPR011162 MHC_I/II-like_Ag-recog

    Graphical View of Domain Structure for InterPro Entry P25311

    ProtoNet protein and cluster: P25311

    2 Blocks protein families:
    IPB001039 MHC class I signature
    IPB003597 Immunoglobulin C-type


    UniProtKB/Swiss-Prot: ZA2G_HUMAN, P25311
    Similarity: Belongs to the MHC class I family
    Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain


    Function
    for AZGP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ZA2G_HUMAN, P25311
    Function: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced
    cancers. May bind polyunsaturated fatty acids

         Genatlas biochemistry entry for AZGP1:
    zinc alpha-2-glycoprotein 1

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AZGP1
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    SwitchGear 3'UTR luciferase reporter plasmid: AZGP1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AZGP1 (see all 7)
    OriGene shRNA RFP: AZGP1
    OriGene siRNA: AZGP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AZGP1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for AZGP1

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AZGP1 (see all 3)
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    Cell Line
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    Search LifeMap BioReagents cell lines for AZGP1

    In Situ Assay
    Products:       
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for AZGP1

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004540ribonuclease activity NAS10462714
    GO:0005504fatty acid binding NAS10206894
    GO:0008320protein transmembrane transporter activity NAS6896906


    AZGP1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for AZGP1:
     Synthetic lethal with imatinib 

    Animal Models:
         Mouse knock-outs for AZGP1: Azgp1tm1Lex Azgp1tm1.1Sbah
         5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Azgp1):
     adipose tissue  growth/size  hematopoietic system  homeostasis/metabolism  immune system 

    AZGP1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for AZGP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AZGP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/60 Interacting proteins for AZGP1 (P253113 ENSP000002924014) via UniProtKB, MINT, STRING, and/or I2D (see all 60)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP53Q70EK83, ENSP000002740304I2D: score=2 STRING: ENSP00000274030
    ITGAVP067563, ENSP000002610234I2D: score=1 STRING: ENSP00000261023
    APCP250543I2D: score=2 
    C12orf44Q9BSB43I2D: score=1 
    GOSR1O952493I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response IEA--
    GO:0007155cell adhesion ISS--
    GO:0008285negative regulation of cell proliferation NAS10462714
    GO:0016042lipid catabolic process NAS10206894
    GO:0019882antigen processing and presentation IEA--


    AZGP1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for AZGP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    AZGP1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AZGP1

    2 DrugBank Compounds for AZGP1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Alpha-D-Mannose-- 3458-28-4target----
    O-Sialic Acid-- --target----

    7 Novoseek chemical compound relationships for AZGP1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    polyacrylamide 44.7 3 1592045 (1), 2265857 (1)
    zinc 27.9 30 12190871 (9), 11309332 (2), 17503403 (1), 20355218 (1) (see all 6)
    polyethylene glycol 12.7 10 15477100 (2)
    lipid 9.12 11 20432169 (2), 10206894 (2), 11425849 (2), 15620688 (1) (see all 7)
    fatty acid 0 3 15477100 (1), 11425849 (1)
    estrogen 0 1 1444749 (1)
    serine 0 1 15595735 (1)

    Search CenterWatch for drugs/clinical trials and news about AZGP1 / ZA2G 

    Transcripts
    for AZGP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for AZGP1 gene: 
    NM_001185.3  

    Unigene Cluster for AZGP1:

    Alpha-2-glycoprotein 1, zinc-binding
    Hs.546239  [show with all ESTs]
    Unigene Representative Sequence: BC014470
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000483612 ENST00000292401(uc003ush.3) ENST00000419575 ENST00000411734
    ENST00000477251 ENST00000495765

    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AZGP1 (see all 7)
    OriGene shRNA RFP: AZGP1
    OriGene siRNA: AZGP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AZGP1
    Clone
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    GenScript: all cDNA clones in your preferred vector: AZGP1 (NM_001185)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AZGP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AZGP1

    Additional cDNA sequence: 

    BC005306.1 BC005908.1 BC014470.1 BC033830.1 D90427.1 M76707.1 X59766.1 

    9 DOTS entries:

    DT.454242  DT.95123268  DT.100819191  DT.95275314  DT.100819194  DT.86855291  DT.86855292  DT.92445589 
    DT.95275316 

    24/320 AceView cDNA sequences (see all 320):

    T29473 CA946332 BM982830 AF503615 CD723079 BM795361 T50792 CD722298 
    CD722721 CD722282 BM981240 CD722675 T74702 AA449344 CK430006 CD723049 
    CB305376 CD722925 BI860607 CD722869 CB122300 BC005306 BC038208 AA916811 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for AZGP1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5
    SP1:              -           -           -         
    SP2:                                                
    SP3:              -           -                     


    ECgene alternative splicing isoforms for AZGP1

    Expression
    for AZGP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AZGP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGACTCTGGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See AZGP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AZGP1

    SOURCE GeneReport for Unigene cluster: Hs.546239

    UniProtKB/Swiss-Prot: ZA2G_HUMAN, P25311
    Tissue specificity: Blood plasma, seminal plasma, urine, saliva, sweat, epithelial cells of various human glands, liver

        SABiosciences Custom PCR Arrays for AZGP1
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    In Situ
    Assay Products:     
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    Orthologs
    for AZGP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for AZGP1 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves F1NM79_CHICK6
    --
    (see all 15)    		 --
    		 36(a)
    32(a)
    (see all 15)    		 many ↔ many
    many ↔ many
    (see all 15)    		 16(40458-41204)
    Un(62829135-62830402)
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    (see all 25)    		 --
    		 41(a)
    41(a)
    (see all 25)    		 many ↔ many
    many ↔ many
    (see all 25)    		 AAWZ02039289(783-2823)
    AAWZ02038573(7605-9645)
    zebrafish
    (Danio rerio)    		 Actinopterygii si:ch211-287j19.66
    CABZ01029904.16
    (see all 7)    		 --
    		 25(a)
    25(a)
    (see all 7)    		 many ↔ many
    many ↔ many
    (see all 7)    		 1(47613228-47619236)
    Zv9_NA257(89256-94080)


    ENSEMBL Gene Tree for AZGP1 (if available)
    TreeFam Gene Tree for AZGP1 (if available) 

    Paralogs
    for AZGP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AZGP1 gene
    MICA2  MICB2  
    18/97 SIMAP similar genes for AZGP1 using alignment to 4 protein entries:     ZA2G_HUMAN (see all proteins) (see all similar genes):
    HLA-B*3531    HLA-B*47RG    HLA-B52    EA2.1    HLA C*    HLA G locus
    HLA-B*15IL    HLA-B*35KM    HLA-B*35SRE    HLA-B*4202    HLA-B*5101 variant    HLA-B52v
    HLA-B*40    HLA-B*51IM    HLA-B*27    HLA -B    HLA-B*1805    HLA-B35

    AZGP1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for AZGP1
    PGOHUM00000250897 PGOHUM00000250957


    Genomic Variants
    for AZGP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/243 NCBI SNPs in AZGP1 are shown (see all 243)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1825331041,2
    		--99563873(+) TACAAC/TCCCTG 1 -- int10--------
    rs1866328601,2
    		--99563949(+) ACACCC/GCTTGT 1 -- int10--------
    rs25278821,2
    		C,F,H,--99563961(-) CTCTCT/CCAATA 1 -- int122Minor allele frequency- C:0.45NS EA NA WA CSA 2141
    rs102351281,2
    		C,--99563984(+) ccccaA/Gctggg 1 -- int10--------
    rs1396030421,2
    		--99564107(+) AGTAAC/TATCAT 1 -- int10--------
    rs1825645091,2
    		--99564118(+) CCTCTC/TCCTTC 1 -- int10--------
    rs1872234911,2
    		--99564180(+) CCAAGG/TGAAAG 1 -- int10--------
    rs1497807191,2
    		--99564234(+) GGAACA/CATGGC 1 -- int10--------
    rs1928686851,2
    		--99564412(+) TGGGGA/GTGGGC 1 -- ut310--------
    rs1853882031,2
    		--99564416(+) GGTGGA/GCTCAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for AZGP1 (99564343 - 99573780 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for AZGP1
         4 CNVs: 37533 64900 2104 7658

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    Disorders / Diseases
    for AZGP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    AZGP1 for disorders           About GeneDecksing

    OMIM gene information: 194460    OMIM disorders: --

    20/26 diseases for AZGP1 (see all 26):    About MalaCards
    clear cell hidradenoma    hidrocystoma    breast cyst    scotoma
    hidradenoma    intrahepatic cholangiocarcinoma    insulin resistance    syndactyly
    multiple sclerosis    breast carcinoma    cholangiocarcinoma    breast disease
    prostate cancer    breast cancer    lung adenocarcinoma    prostate adenocarcinoma
    adenocarcinoma    cervical cancer    alzheimer's disease    cervicitis

    9 Novoseek disease relationships for AZGP1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    breast cysts 63 4 9114041 (2), 1828959 (1)
    breast diseases 54.7 2 9114041 (1)
    breast carcinoma 44.6 6 1444749 (2), 8049458 (1), 9114041 (1), 8307568 (1)
    breast cancer 10.5 2 2202419 (1)
    cancer 8.4 9 12190871 (2), 16475792 (1), 15620688 (1), 20198343 (1) (see all 7)
    prostate cancer 0.471 10 11309332 (4), 16598739 (2), 17317883 (2)
    metastasis 0 2 1444749 (1), 16598739 (1)
    tumors 0 13 11309332 (3), 12190871 (2), 2244662 (1), 16598739 (1) (see all 7)
    melanoma 0 2 12190871 (1)

    Human Genome Epidemiology (HuGE) Navigator: AZGP1 (1 document)

    Export disorders for AZGP1 gene to outside databases

    Publications
    for AZGP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AZGP1 gene, integrated from 9 sources (see all 116):
    (articles sorted by number of sources associating them with AZGP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and nucleotide sequence of a human Zn-alpha 2-glycoprotein cDNA and chromosomal assignment of its gene. (PubMed id 2049092)1, 2, 3, 9 Ueyama H.... Ohkubo I. (1991)
    2. Biochemical characterization and crystalization of human Zn-alpha2- glycoprotein, a soluble class I major histocompatibility complex homolog. (PubMed id 9114041)1, 2, 9 Sanchez L.M.... Bjorkman P.J. (1997)
    3. Crystallographic studies of ligand binding by Zn-alpha2- glycoprotein. (PubMed id 15477100)1, 2, 9 Delker S.L.... Bjorkman P.J. (2004)
    4. Hydrophobic ligand binding by Zn-alpha 2-glycoprotein, a soluble fat- depleting factor related to major histocompatibility complex proteins. (PubMed id 11425849)1, 2, 9 Kennedy M.W.... Sanchez L.M. (2001)
    5. Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules. (PubMed id 10206894)1, 2, 9 Sanchez L.M.... Bjorkman P.J. (1999)
    6. Molecular cloning and chromosomal assignment of the gene for human Zn-alpha 2-glycoprotein. (PubMed id 8241150)1, 2, 9 Ueyama H.... Ohkubo I. (1993)
    7. Human Zn-alpha 2-glycoprotein: complete genomic sequence, identification of a related pseudogene and relationship to class I major histocompatibility complex genes. (PubMed id 8307568)1, 2, 9 Freije J.P.... Lopez-Otin C. (1993)
    8. Human Zn-alpha 2-glycoprotein cDNA cloning and expression analysis in benign and malignant breast tissues. (PubMed id 1915885)1, 2, 9 Freije J.P.... Lopez-Otin C. (1991)
    9. Crystal structure of the novel complex formed between zinc alpha2- glycoprotein (ZAG) and prolactin-inducible protein (PIP) from human seminal plasma. (PubMed id 18930737)1, 2 Hassan M.I....Singh T.P. (2008)
    10. Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. (PubMed id 16740002)1, 2 Ramachandran P....Loo J.A. (2006)

    External Searches for AZGP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing AZGP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 563 HGNC: 910 AceView: AZGP1 Ensembl:ENSG00000160862 euGenes: HUgn563
    ECgene: AZGP1 H-InvDB: AZGP1

    Other Databases showing AZGP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing AZGP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AZGP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for AZGP1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for AZGP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for AZGP1 gene:
    Search GeneIP for patents involving AZGP1

    GeneCards and IP:
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