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Aliases for AVPI1 Gene

Aliases for AVPI1 Gene

  • Arginine Vasopressin Induced 1 2 3 5
  • Arginine Vasopressin-Induced 1 2 3
  • AVP-Induced Protein 1 3 4
  • Vasopressin-Induced Transcript 3
  • PP5395 3
  • VIP32 3
  • VIT32 3

External Ids for AVPI1 Gene

Previous GeneCards Identifiers for AVPI1 Gene

  • GC10M099102
  • GC10M099427
  • GC10M093062

Summaries for AVPI1 Gene

GeneCards Summary for AVPI1 Gene

AVPI1 (Arginine Vasopressin Induced 1) is a Protein Coding gene.

UniProtKB/Swiss-Prot for AVPI1 Gene

  • May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.

Gene Wiki entry for AVPI1 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AVPI1 Gene

Genomics for AVPI1 Gene

Regulatory Elements for AVPI1 Gene

Promoters for AVPI1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around AVPI1 on UCSC Golden Path with GeneCards custom track

Genomic Location for AVPI1 Gene

Chromosome:
10
Start:
97,677,424 bp from pter
End:
97,687,323 bp from pter
Size:
9,900 bases
Orientation:
Minus strand

Genomic View for AVPI1 Gene

Genes around AVPI1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AVPI1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AVPI1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AVPI1 Gene

Proteins for AVPI1 Gene

  • Protein details for AVPI1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T686-AVPI1_HUMAN
    Recommended name:
    Arginine vasopressin-induced protein 1
    Protein Accession:
    Q5T686
    Secondary Accessions:
    • Q53G32
    • Q9H2R9
    • Q9HBN9

    Protein attributes for AVPI1 Gene

    Size:
    147 amino acids
    Molecular mass:
    16773 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAG44474.1; Type=Frameshift; Positions=28; Evidence={ECO:0000305};

neXtProt entry for AVPI1 Gene

Proteomics data for AVPI1 Gene at MOPED

Post-translational modifications for AVPI1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for AVPI1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Cloud-Clone Corp. Antibodies for AVPI1

No data available for DME Specific Peptides for AVPI1 Gene

Domains & Families for AVPI1 Gene

Protein Domains for AVPI1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for AVPI1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with AVPI1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for AVPI1 Gene

Function for AVPI1 Gene

Molecular function for AVPI1 Gene

UniProtKB/Swiss-Prot Function:
May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.
genes like me logo Genes that share phenotypes with AVPI1: view

Animal Model Products

miRNA for AVPI1 Gene

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for AVPI1 Gene

Localization for AVPI1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for AVPI1 Gene COMPARTMENTS Subcellular localization image for AVPI1 gene
Compartment Confidence
cytosol 2
mitochondrion 2
nucleus 2
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for AVPI1 Gene

Pathways & Interactions for AVPI1 Gene

SuperPathways for AVPI1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for AVPI1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000187 activation of MAPK activity IEA --
genes like me logo Genes that share ontologies with AVPI1: view

No data available for Pathways by source and SIGNOR curated interactions for AVPI1 Gene

Drugs & Compounds for AVPI1 Gene

(1) Additional Compounds for AVPI1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
sodium
  • Sodium
  • Sodium ion
7440-23-5
genes like me logo Genes that share compounds with AVPI1: view

Transcripts for AVPI1 Gene

mRNA/cDNA for AVPI1 Gene

(1) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(203) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for AVPI1 Gene

Arginine vasopressin-induced 1:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for AVPI1 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4
SP1:
SP2: - -
SP3:

Relevant External Links for AVPI1 Gene

GeneLoc Exon Structure for
AVPI1
ECgene alternative splicing isoforms for
AVPI1

Expression for AVPI1 Gene

mRNA expression in normal human tissues for AVPI1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for AVPI1 Gene

This gene is overexpressed in Bone (68.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for AVPI1 Gene



SOURCE GeneReport for Unigene cluster for AVPI1 Gene Hs.23918

genes like me logo Genes that share expression patterns with AVPI1: view

Protein tissue co-expression partners for AVPI1 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for AVPI1 Gene

Orthologs for AVPI1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for AVPI1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia AVPI1 35
  • 86.01 (n)
  • 87.41 (a)
AVPI1 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia AVPI1 35
  • 86.62 (n)
  • 87.76 (a)
AVPI1 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Avpi1 35
  • 80 (n)
  • 78.57 (a)
Avpi1 16
Avpi1 36
  • 77 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia AVPI1 35
  • 99.09 (n)
  • 97.96 (a)
AVPI1 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Avpi1 35
  • 80.71 (n)
  • 80 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 73 (a)
OneToMany
-- 36
  • 66 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia AVPI1 36
  • 38 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia avpi1 35
  • 53.1 (n)
  • 53.79 (a)
Species with no ortholog for AVPI1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for AVPI1 Gene

ENSEMBL:
Gene Tree for AVPI1 (if available)
TreeFam:
Gene Tree for AVPI1 (if available)

Paralogs for AVPI1 Gene

No data available for Paralogs for AVPI1 Gene

Variants for AVPI1 Gene

Sequence variations from dbSNP and Humsavar for AVPI1 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
VAR_031405 -

Structural Variations from Database of Genomic Variants (DGV) for AVPI1 Gene

Variant ID Type Subtype PubMed ID
esv2739918 CNV Deletion 23290073
esv2739929 CNV Deletion 23290073
esv2665093 CNV Deletion 23128226

Variation tolerance for AVPI1 Gene

Residual Variation Intolerance Score: 91.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.56; 88.94% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for AVPI1 Gene

HapMap Linkage Disequilibrium report
AVPI1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AVPI1 Gene

Disorders for AVPI1 Gene

Relevant External Links for AVPI1

Genetic Association Database (GAD)
AVPI1
Human Genome Epidemiology (HuGE) Navigator
AVPI1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
AVPI1

No disorders were found for AVPI1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AVPI1 Gene

Publications for AVPI1 Gene

  1. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 48 67
  2. AVP-induced VIT32 gene expression in collecting duct cells occurs via trans-activation of a CRE in the 5'-flanking region of the VIT32 gene. (PMID: 15140762) Thomas C.P. … Liu K.Z. (Am. J. Physiol. Renal Physiol. 2004) 3 23
  3. A novel vasopressin-induced transcript promotes MAP kinase activation and ENaC downregulation. (PMID: 12356727) Nicod M. … Firsov D. (EMBO J. 2002) 3 23
  4. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3
  5. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3

Products for AVPI1 Gene

Sources for AVPI1 Gene

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