External Ids for AVIL Gene
The protein encoded by this gene is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia. [provided by RefSeq, Jul 2008]
GeneCards Summary for AVIL Gene
AVIL (Advillin) is a Protein Coding gene. Diseases associated with AVIL include lennox-gastaut syndrome. GO annotations related to this gene include actin binding. An important paralog of this gene is VIL1.
UniProtKB/Swiss-Prot for AVIL Gene
Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.