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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AVEN Gene

protein-coding   GIFtS: 52
GCID: GC15M034158

apoptosis, caspase activation inhibitor
 Explore 17 diseases affiliated with
AVEN via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for AVEN    

Aliases
for AVEN gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Apoptosis, Caspase Activation Inhibitor1 2
PDCD121 2
Cell Death Regulator Aven2
Programmed Cell Death 122

External Ids:    HGNC: 135091   Entrez Gene: 570992   Ensembl: ENSG000001698577   OMIM: 6052655   UniProtKB: Q9NQS13   

Export aliases for AVEN gene to outside databases

Previous GC identifers: GC15M029400 GC15M026866 GC15M031737 GC15M031874 GC15M031945 GC15M011021


Summaries
for AVEN gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: AVEN_HUMAN, Q9NQS1
Function: Protects against apoptosis mediated by Apaf-1




Genomic Views
for AVEN gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AVEN gene promoter:
         STAT5B   Elk-1   NRF-2   NCX/Ncx   STAT5A   Nkx2-5   c-Ets-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for AVEN

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AVEN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q13.1   Ensembl cytogenetic band:  15q14   HGNC cytogenetic band: 15q13.1

AVEN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AVEN gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M034158:  view genomic region     (about GC identifiers)

Start:
 34,158,428 bp from pter      End:
 34,331,377 bp from pter
Size:
 172,950 bases      Orientation:
 minus strand

Proteins
for AVEN gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: AVEN_HUMAN, Q9NQS1 (See protein sequence)
Recommended Name: Cell death regulator Aven  
Size: 362 amino acids; 38506 Da
Subunit: Binds Apaf-1, BCL-2 and BAD (Bcl-xl)
Subcellular location: Endomembrane system; Peripheral membrane protein. Note=Associated with intracellular membranes

Explore the universe of human proteins at neXtProt for AVEN: NX_Q9NQS1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NQS1

    • AVEN Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_065104.1  
    ENSEMBL proteins: 
     ENSP00000306822   ENSP00000452906  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Purified Protein: AVEN
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    Novus Biologicals AVEN Proteins
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for AVEN

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA10949025
    GO:0005624membrane fraction ----
    GO:0012505endomembrane system IEA--
    GO:0016020membrane IDA10949025


    AVEN for ontologies           About GeneDecksing



    AVEN Antibody Products: 
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    Uscn Antibodies for AVEN
    ThermoFisher Antibodies for AVEN

    Assay Products for AVEN: 
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    Uscn ELISAs and CLIAs for AVEN

    Protein Domains /
    Families
    for AVEN gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    AVEN for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR026187 Aven

    Graphical View of Domain Structure for InterPro Entry Q9NQS1

    ProtoNet protein and cluster: Q9NQS1


    Function
    for AVEN gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: AVEN_HUMAN, Q9NQS1
    Function: Protects against apoptosis mediated by Apaf-1

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AVEN
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate AVEN (see all 15):
    hsa-miR-30c hsa-miR-98 hsa-miR-3607-3p hsa-let-7d hsa-miR-30d hsa-let-7c hsa-let-7i hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmid: AVEN 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AVEN (see all 7)
    OriGene shRNA RFP: AVEN
    OriGene siRNA: AVEN
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AVEN

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for AVEN

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AVEN (see all 4)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AVEN 

    Cell Line
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    Search LifeMap BioReagents cell lines for AVEN

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AVEN

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI10949025


    AVEN for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Aven):
     cellular 

    AVEN for phenotypes           About GeneDecksing


    Pathways & Interactions
    for AVEN gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Apoptosis and Autophagy
    		Apoptosis and Autophagy1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for AVEN
        Apoptosis and Autophagy



    AVEN for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for AVEN

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/10 Interacting proteins for AVEN (Q9NQS12, 3 ENSP000003068224) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APAF1O147272, 3, ENSP000003530594MINT-17186 MINT-17187 I2D: score=3 STRING: ENSP00000353059
    BCL2L1Q078173, ENSP000003025644I2D: score=2 STRING: ENSP00000302564
    SMURF1Q9HCE73, ENSP000003546214I2D: score=2 STRING: ENSP00000354621
    BCL2P104153, ENSP000003296234I2D: score=1 STRING: ENSP00000329623
    AXIN2Q9Y2T13I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0043066negative regulation of apoptotic process IDA10949025


    AVEN for ontologies           About GeneDecksing



    Drugs & Compounds
    for AVEN gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    AVEN for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AVEN
    1 Novoseek chemical compound relationship for AVEN gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    thapsigargin 35 2 11276013 (2)

    Search CenterWatch for drugs/clinical trials and news about AVEN 

    Transcripts
    for AVEN gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for AVEN gene: 
    NM_020371.2  

    Unigene Cluster for AVEN:

    Apoptosis, caspase activation inhibitor
    Hs.555966  [show with all ESTs]
    Unigene Representative Sequence: NM_020371
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000306730(uc001zhj.3) ENST00000560649 ENST00000558136

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AVEN
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate AVEN (see all 15):
    hsa-miR-30c hsa-miR-98 hsa-miR-3607-3p hsa-let-7d hsa-miR-30d hsa-let-7c hsa-let-7i hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmid: AVEN 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AVEN (see all 7)
    OriGene shRNA RFP: AVEN
    OriGene siRNA: AVEN
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AVEN
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AVEN (see all 4)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: AVEN (NM_020371)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AVEN 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AVEN

    Additional cDNA sequence: 

    AF283508.1 AK025888.1 BC010488.1 BC063533.1 

    2 DOTS entries:

    DT.410128  DT.409791 

    24/69 AceView cDNA sequences (see all 69):

    BU620526 AI018614 BC010488 AL541314 AA630591 BM680720 BC063533 BM711332 
    BG285015 BX090037 BM807941 BM665905 AI373132 AI473327 CR618548 CR619789 
    AW673669 NM_020371 BU856249 AI804357 AF283508 BM811419 BM760540 CD106819 

    GeneLoc Exon Structure


    Expression
    for AVEN gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AVEN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CATTTGGCCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    AVEN expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ progenitor E69 (Embryonic Progenitor Cell)
    PureStem™ progenitor T36 (Embryonic Progenitor Cell)
    Definitive endoderm-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See AVEN Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AVEN

    SOURCE GeneReport for Unigene cluster: Hs.555966

    UniProtKB/Swiss-Prot: AVEN_HUMAN, Q9NQS1
    Tissue specificity: Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart,
    skeletal muscle, liver, kidney and pancreas

        SABiosciences Expression via Pathway-Focused PCR Arrays including AVEN: 
              Apoptosis 384HT in human mouse rat
              Apoptosis in human mouse rat

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AVEN

    Orthologs
    for AVEN gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for AVEN gene from 4/8 species (see all 8)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Aven1 , 5 apoptosis, caspase activation inhibitor1, 5 80.02(n)1
    75.44(a)1    		   2 (57.04 cM)5
    742681  NM_028844.31  NP_083120.21 
     1124929645 
    chicken
    (Gallus gallus)    		 Aves AVEN1 apoptosis, caspase activation inhibitor 60.21(n)
    52.6(a)    		   395127  NM_001005791.1  NP_001005791.1 
    lizard
    (Anolis carolinensis)    		 Reptilia AVEN6
    		 --
    		 46(a)
    		 1 ↔ 1
    		 1(33517676-33537911)
    zebrafish
    (Danio rerio)    		 Actinopterygii aven1 apoptosis, caspase activation inhibitor 52.32(n)
    44.04(a)    		   692323  NM_001045292.2  NP_001038757.2 


    ENSEMBL Gene Tree for AVEN (if available)
    TreeFam Gene Tree for AVEN (if available) 

    Paralogs
    for AVEN gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for AVEN gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2326 NCBI SNPs in AVEN are shown (see all 2326)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 15 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs2009388951,2
    		--34158886(+) TGCTCA/GGGTTC 2 P syn10--------
    rs1476798131,2
    		C,F--34158888(+) CTCAGG/CTTCCA 2 /P /A mis12Minor allele frequency- C:0.00NA EU 5869
    rs1423180411,2
    		C--34158896(+) CCATGT/ATTTTT 2 /N /I mis11Minor allele frequency- A:0.00NA 4544
    rs1864102421,2
    		C,--34158902(+) TTTTTC/TCTTCA 2 E G mis10--------
    rs1996188871,2
    		--34158931(+) CAAACC/TGGGGG 1 -- spa10--------
    rs1469386401,2
    		--34158962(+) CCTCAA/GATGAG 1 -- int10--------
    rs1177033721,2
    		C,F,--34158981(+) TTGAAG/CGTATA 1 -- int12Minor allele frequency- C:0.04NA EU 713
    rs1379046971,2
    		--34159091(+) GTAGAC/GGATTT 1 -- int10--------
    rs2008211121,2
    		--34159137(+) GTTGG-/TTTTTT 1 -- int10--------
    rs1912993221,2
    		--34159193(+) CAGCAC/GTCCTG 1 -- int10--------

    HapMap Linkage Disequilibrium report for AVEN (34158428 - 34331377 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 11 variations for AVEN
         4 CNVs: 53263 49527 7058 72231
         6 Indels: 10706 41748 102072 61432 72233 11787
         1 Inversion: 59727

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    Disorders / Diseases
    for AVEN gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    AVEN for disorders           About GeneDecksing

    OMIM gene information: 605265    OMIM disorders: --

    17 diseases for AVEN:    About MalaCards
    prader-willi syndrome    malignant pleural mesothelioma    glucocorticoid resistance    acute lymphoblastic leukemia
    lymphoblastic leukemia    kaposi's sarcoma    emphysema    myeloid leukemia
    sarcoma    leukemia    alzheimer's disease    prostate cancer
    cholesterol    prostatitis    pancreatitis    neuronitis
    alcoholism

    2 diseases from the University of Copenhagen DISEASES database for AVEN:
    Schizoid personality disorder     Alexithymia

    2 Novoseek disease relationships for AVEN gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 3 15156195 (1), 17592138 (1), 15540893 (1)
    cancer 0 1 17592138 (1)

    Human Genome Epidemiology (HuGE) Navigator: AVEN (8 documents)

    Export disorders for AVEN gene to outside databases

    Publications
    for AVEN gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AVEN gene, integrated from 9 sources (see all 51):
    (articles sorted by number of sources associating them with AVEN)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf- 1. (PubMed id 10949025)1, 2, 3 Chau B.N.... Hardwick J.M. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    4. Apoptosis-inhibitor Aven is downregulated in defectiv e spermatogenesis and a novel estrogen target gene in mammalian testis. (PubMed id 21718987)1 Laurentino S....Socorro S. (2011)
    5. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    7. Physiogenomic analysis of statin-treated patients: do main-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)1 RuaA+o G....Wu A.H. (2010)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    9. Regulation of the ATM-activator protein Aven by CRM1- dependent nuclear export. (PubMed id 20935510)1 Esmaili A.M....Irusta P.M. (2010)
    10. Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)1 Flachsbart F....Nebel A. (2010)

    External Searches for AVEN gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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      Query String
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    Genome Databases showing AVEN gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57099 HGNC: 13509 AceView: AVEN Ensembl:ENSG00000169857 euGenes: HUgn57099
    ECgene: AVEN H-InvDB: AVEN

    Other Databases showing AVEN gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing AVEN gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AVEN Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for AVEN gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for AVEN gene:
    Search GeneIP for patents involving AVEN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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     Regulatory tfbs in AVEN promoter
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     AVEN Proteins, Antibodies, CLIAs, and ELISAs
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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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