ATXN2L Gene
protein-coding GIFtS: 51
GCID: GC16P028834
|
|
ataxin 2-like
| |
Aliases
for ATXN2L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ataxin 2-Like1 2 | | A2LP2 3 | | A2D1 2 3 5 | | A2RP2 3 | | Ataxin-2 Domain Protein2 3 | | A2lp1 | | Ataxin-2-Related Protein2 3 | | Ataxin 2 Related Protein2 | | A2LG2 3 | | Ataxin-2-Like Protein2 |
Export aliases for ATXN2L gene to outside databasesPrevious GC identifers: GC16P028741 GC16P026701 |
Summaries
for ATXN2L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ATXN2L:
This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellarataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternativelyspliced transcripts encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)
Gene Wiki entry for ATXN2L
|
Genomic Views
for ATXN2L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ATXN2L gene promoter:
E2F-4 E2F-3a Sox5 E2F-5 FOXD3 E2F-2 Egr-2 HEN1 E2F E2F-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATXN2L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATXN2L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p11 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11ATXN2L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P028834: view genomic region
(about GC identifiers)
Start:
|
28,834,356 bp from pter |
End:
|
28,848,558 bp from pter |
Size:
|
14,203 bases |
Orientation:
|
plus strand |
|
Proteins
for ATXN2L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ATX2L_HUMAN, Q8WWM7 (See
protein sequence)Recommended Name: Ataxin-2-like protein Size: 1075 amino acids; 113374 Da
Subunit: Interacts with MPL/TPOR and EPOR and dissociates after ligand stimulation
Subcellular location: Membrane; Peripheral membrane protein
Sequence caution: Sequence=AAC69607.1; Type=Frameshift; Positions=31, 429, 432, 446; Sequence=AAO12056.1;Type=Frameshift; Positions=Several; Sequence=AAO12057.1; Type=Frameshift; Positions=Several; Sequence=AAO12058.1;Type=Frameshift; Positions=Several; Sequence=AAO12058.1; Type=Miscellaneous discrepancy; Note=Exon duplication;Sequence=AAO12059.1; Type=Frameshift; Positions=Several; Sequence=AAO12059.1; Type=Miscellaneous discrepancy;Note=Exon duplication; Sequence=AAO12060.1; Type=Frameshift; Positions=Several; Sequence=AAO12060.1;Type=Miscellaneous discrepancy; Note=Exon duplication;
Secondary accessions: A8K1R6 B9EGM2 E9PAR9 O95135 Q6NVJ8 Q6PJW6 Q8IU61 Q8IU95 Q8WWM3 Q8WWM4 Q8WWM5Q8WWM6 Q99703Alternative splicing: 8 isoforms: Q8WWM7-1 Q8WWM7-2 Q8WWM7-3 Q8WWM7-4 Q8WWM7-5 Q8WWM7-6 Q8WWM7-7 Q8WWM7-8 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ATXN2L: NX_Q8WWM7
Post-translational modifications:
Thrombopoietin triggers the phosphorylation on tyrosine residues in a way that is dependent on MPL C-terminal domain1
Arg-361 is dimethylated, probably to asymmetric dimethylarginine1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WWM7
ATXN2L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_009176.2 NP_059867.3 NP_663760.1 NP_680780.1 NP_680781.1 NP_680782.1
ENSEMBL proteins: ENSP00000341459 ENSP00000315650 ENSP00000378917 ENSP00000338718 ENSP00000372133 ENSP00000457613 ENSP00000454516 ENSP00000456752 ENSP00000456812 ENSP00000457599 ENSP00000456162 ENSP00000454757 ENSP00000454588 ENSP00000455981 ENSP00000455427 ENSP00000455560
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ATXN2L for ontologies About GeneDecksing
ATXN2L Antibody Products:
Assay Products for ATXN2L: |
Protein
Domains /
Families
for ATXN2L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATXN2L for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8WWM7ProtoNet protein and cluster: Q8WWM7 2 Blocks protein families: IPB009604 Ataxin-2 IPB009818 Ataxin-2
UniProtKB/Swiss-Prot: ATX2L_HUMAN, Q8WWM7Similarity: Belongs to the ataxin-2 family |
Function
for ATXN2L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATXN2L (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATXN2L (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): ATXN2L (NM_148414) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATXN2L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATXN2L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATXN2L |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
ATXN2L for ontologies About GeneDecksing
|
Pathways & Interactions
for ATXN2L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATXN2L
5/15 Interacting proteins for ATXN2L (Q8WWM72, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 15)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- | | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly |
IDA | -- | | GO:0034063 | stress granule assembly |
IMP | -- |
ATXN2L for ontologies About GeneDecksing
|
Drugs & Compounds
for ATXN2L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ATXN2L
Search CenterWatch for drugs/clinical trials and news about ATXN2L / ATX2L
|
Transcripts
for ATXN2L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATXN2L gene (6 alternative transcripts): NM_007245.3 NM_017492.3 NM_145714.2 NM_148414.2 NM_148415.2 NM_148416.2 Unigene Cluster for ATXN2L: Ataxin 2-like Hs.460499 [show with all ESTs]Unigene Representative Sequence: AY18833818/26 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26): ENST00000563314(uc002drg.3) ENST00000340394(uc002dra.3) ENST00000325215
ENST00000395547(uc002dqy.3 uc002drb.3 uc010vdb.2 uc002dre.3)
ENST00000336783(uc002drc.3) ENST00000382686(uc010byl.1 uc002dqz.3)
ENST00000564304 ENST00000570200 ENST00000562867 ENST00000568266 ENST00000564656
ENST00000561539 ENST00000566080 ENST00000565971(uc002drf.3) ENST00000570284
ENST00000564284 ENST00000565845 ENST00000562583
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATXN2L (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATXN2L (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 5): ATXN2L (NM_148414) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATXN2L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATXN2L |
Additional cDNA sequence: AF070605.1 AJ317970.1 AJ317971.2 AJ317972.2 AJ317973.2 AJ317974.2 AK289981.1 AL137587.1 AY188334.1 AY188335.1 AY188336.1 AY188337.1 AY188338.1 BC010239.2 BC068012.1 BC082760.1 BC136584.1 BC144269.1 U70671.1 24/35 DOTS entries (see all 35): DT.95087964 DT.100819527 DT.448504 DT.86855040 DT.102843674 DT.95226494 DT.102843677 DT.91963213 DT.100059552 DT.97848817 DT.100819548 DT.100059543 DT.120696106 DT.92448175 DT.100819531 DT.95226589 DT.120698104 DT.75155177 DT.120695726 DT.120696691 DT.120696028 DT.40294896 DT.95277367 DT.100692100 24/417 AceView cDNA sequences (see all 417): BM549871 AA775659 BM541819 CN480132 BU685001 BM797547 BU682501 BE276160 BQ223699 AW608627 BU554112 BQ053420 AL137587 CA396242 AW245940 BC068012 AW373269 BQ956385 CA952491 AW058618 BM456155 AF070605 AA906126 AI804813
GeneLoc Exon Structure
5/16 Alternative Splicing Database (ASD) splice patterns (SP) for ATXN2L (see all 16) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ |
|---|
|
| SP1: | | | | | - | | - | | - | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | - | | | | | | | | - | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | ^ | 20 | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23 | ^ | 24 | ^ | 25a | · | 25b | · | 25c | ^ | 26a | · | 26b | ^ | 27a | · | 27b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ATXN2L
|
Expression
for ATXN2L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATXN2L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTGGAGGGA
About this image
See ATXN2L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATXN2L
SOURCE GeneReport for Unigene cluster: Hs.460499
UniProtKB/Swiss-Prot: ATX2L_HUMAN, Q8WWM7Tissue specificity: Expressed at high levels in thymus, lymph node, spleen, fetal kidney and adult testis.Constitutively associated with MPL and EPOR in hematopoietic cells
SABiosciences Custom PCR Arrays for ATXN2L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATXN2L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATXN2L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATXN2L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATXN2L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATXN2L |
Orthologs
for ATXN2L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ATXN2L gene from 6/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
ATXN2L6 |
-- |
76(a) |
1 ↔ 1 |
GL343287.1(403003-418281) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.140452 |
Xenopus laevis transcribed sequence with weak similarity more |
77.04(n) |
|
CA793895.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufi19h052 |
Danio rerio cDNA clone MGC66471 IMAGE2601096, complete more |
72.28(n) |
|
BC057536.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Atx26 |
Ataxin-2 |
15(a) |
1 → many |
3R(11234158-11242999) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
CID46CID36 |
ctc-interacting domain 3 protein |
17(a)14(a) |
many ↔ manymany ↔ many |
3(4636254-4640981) 1(20221060-20225948) |
rice
(Oryza sativa) |
Liliopsida |
-- |
ataxin-2 related protein, putative, expressed |
15(a) |
1 → many |
2(16531342-16539876) |
ENSEMBL Gene Tree for ATXN2L (if available)
TreeFam Gene Tree for ATXN2L (if available) |
Paralogs
for ATXN2L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ATXN2L gene
- ATXN22
1 SIMAP similar gene for ATXN2L using alignment to 11 protein entries: ATX2L_HUMAN (see all proteins):ATXN2
ATXN2L for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ATXN2L
PGOHUM00000232600
|
Genomic Variants
for ATXN2L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATXN2L (28834356 - 28848558 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ATXN2L
2 CNVs: 72517 3999 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATXN2L |
|
Disorders
/ Diseases
for ATXN2L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATXN2L for disorders About GeneDecksing
OMIM gene information: 607931
OMIM disorders: --
6  diseases for ATXN2L: About MalaCardsspinocerebellar ataxia ataxia olivopontocerebellar atrophy inflammatory bowel disease
crohn's disease alzheimer's disease
1 disease from the University of Copenhagen DISEASES database for ATXN2L:Spinocerebellar ataxia Human Genome Epidemiology (HuGE) Navigator: ATXN2L (1 document)
Export disorders for ATXN2L gene to outside databases
|
Publications
for ATXN2L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATXN2L gene, integrated from 9 sources (see all 43):
(articles sorted by number of sources associating them with ATXN2L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and expression of the gene for human ataxin-2-related protein on chromosome 16. (PubMed id 14769358)1, 2, 3, 9 Figueroa K.P. and Pulst S.M. (2003)
- Cloning and characterization of a family of proteins associated with Mpl. (PubMed id 11784712)1, 2, 3, 9 Meunier C.F....Courtois G. (2002)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2. (PubMed id 8896555)1, 2 Pulst S.-M....Sahba S. (1996)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for ATXN2L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ATXN2L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ATXN2L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ATXN2L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ATXN2L | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ATXN2L gene:
Search GeneIP for patents involving ATXN2L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ATXN2L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATXN2L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATXN2L | | | OriGene Protein Over-expression Lysate for ATXN2L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATXN2L | | OriGene 3'-UTR Clone for ATXN2L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATXN2L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATXN2L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ATXN2L | | OriGene Custom Protein Services for ATXN2L | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATXN2L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATXN2L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATXN2L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATXN2L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATXN2L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATXN2L |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ATXN2L |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ATXN2L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATXN2L |
|  |  |  | | | | ThermoFisher Antibodies for ATXN2L |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATXN2L |
|
|
|
|
