Aliases for ATXN10 Gene
External Ids for ATXN10 Gene
Previous HGNC Symbols for ATXN10 Gene
Previous GeneCards Identifiers for ATXN10 Gene
This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of a pentanucleotide repeat in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
GeneCards Summary for ATXN10 Gene
ATXN10 (Ataxin 10) is a Protein Coding gene. Diseases associated with ATXN10 include spinocerebellar ataxia 10 and spinocerebellar ataxia type10. Among its related pathways are Akt Signaling and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include identical protein binding and binding.
UniProtKB/Swiss-Prot for ATXN10 Gene
Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.