Aliases for ATRN Gene
External Ids for ATRN Gene
Previous GeneCards Identifiers for ATRN Gene
Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, May 2011]
GeneCards Summary for ATRN Gene
ATRN (Attractin) is a Protein Coding gene. Diseases associated with ATRN include shwartzman phenomenon and kidney cortex necrosis. GO annotations related to this gene include receptor activity and carbohydrate binding. An important paralog of this gene is MEGF8.
UniProtKB/Swiss-Prot for ATRN Gene
Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).