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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATPAF2 Gene

protein-coding   GIFtS: 50
GCID: GC17M017881

ATP synthase mitochondrial F1 complex assembly factor 2
 Explore 7 diseases affiliated with
ATPAF2 via
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 Human Malady Compendium 
Biological research products
for ATPAF2    

Aliases
for ATPAF2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
ATP Synthase Mitochondrial F1 Complex Assembly Factor 21 2     LP36631
ATP121 2 3 5     MGC297361
ATP12 Homolog2 3     ATP12p2
Atp12p1     MC5DN12

External Ids:    HGNC: 188021   Entrez Gene: 916472   Ensembl: ENSG000001719537   OMIM: 6089185   UniProtKB: Q8N5M13   

Export aliases for ATPAF2 gene to outside databases

Previous GC identifers: GC17M018166 GC17M019290 GC17M017861 GC17M018122 GC17M017863 GC17M017864 GC17M017918 GC17M017675


Summaries
for ATPAF2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ATPAF2:
This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds
specifically to the F1 alpha subunit and is thought to prevent this subunit from forming nonproductive homooligomers
during enzyme assembly. This gene is located within the Smith-Magenis syndrome region on chromosome 17. An
alternatively spliced transcript variant has been described, but its biological validity has not been determined.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ATPF2_HUMAN, Q8N5M1
Function: May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase)

Gene Wiki entry for ATPAF2


Genomic Views
for ATPAF2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATPAF2 gene promoter:
         POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   IRF-1   POU3F2   MZF-1   c-Myb   Pax-4a   NF-Y   CBF(2)   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ATPAF2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ATPAF2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATPAF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p11.2   Ensembl cytogenetic band:  17p11.2   HGNC cytogenetic band: 17p11.2

ATPAF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATPAF2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M017881:  view genomic region     (about GC identifiers)

Start:
 17,880,723 bp from pter      End:
 17,942,523 bp from pter
Size:
 61,801 bases      Orientation:
 minus strand

Proteins
for ATPAF2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ATPF2_HUMAN, Q8N5M1 (See protein sequence)
Recommended Name: ATP synthase mitochondrial F1 complex assembly factor 2 precursor  
Size: 289 amino acids; 32772 Da
Subunit: Interacts with ATP5A1
Subcellular location: Mitochondrion (Probable)
Sequence caution: Sequence=AAP34466.1; Type=Frameshift; Positions=87;
Secondary accessions: A6NDE5 A8K2J2 Q6XYC7

Explore the universe of human proteins at neXtProt for ATPAF2: NX_Q8N5M1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8N5M1

    • ATPAF2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_663729.1  
    ENSEMBL proteins: 
     ENSP00000462899   ENSP00000463920   ENSP00000463861   ENSP00000434980   ENSP00000417190  
     ENSP00000466008   ENSP00000397198  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ATPAF2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0016607nuclear speck IDA--


    ATPAF2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ATPAF2

    Protein Domains /
    Families
    for ATPAF2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ATPAF2 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR011419 ATP12_ATPase-F1F0-assembly
     IPR023335 ATPase_assmbl_ATP12_dom

    Graphical View of Domain Structure for InterPro Entry Q8N5M1

    ProtoNet protein and cluster: Q8N5M1

    UniProtKB/Swiss-Prot: ATPF2_HUMAN, Q8N5M1
    Similarity: Belongs to the ATP12 family


    Function
    for ATPAF2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ATPF2_HUMAN, Q8N5M1
    Function: May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase)

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11410595


    ATPAF2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for ATPAF2:
     Increased gamma-H2AX phosphory 

    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Atpaf2):
     mortality/aging  skeleton 

    ATPAF2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ATPAF2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATPAF2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5 Interacting proteins for ATPAF2 (Q8N5M13 ENSP000004171904) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATP5A1P257053, ENSP000002820504I2D: score=3 STRING: ENSP00000282050
    ATP5BP065763, ENSP000002620304I2D: score=1 STRING: ENSP00000262030
    IKZF3Q9UKT93I2D: score=1 
    PRDM14Q9GZV83I2D: score=1 
    HDAC6ENSP000003340614STRING: ENSP00000334061
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043461proton-transporting ATP synthase complex assembly NAS14757859


    ATPAF2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ATPAF2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ATPAF2
    Search CenterWatch for drugs/clinical trials and news about ATPAF2 / ATPF2 

    Transcripts
    for ATPAF2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ATPAF2 gene: 
    NM_145691.3  

    Unigene Cluster for ATPAF2:

    ATP synthase mitochondrial F1 complex assembly factor 2
    Hs.528889  [show with all ESTs]
    Unigene Representative Sequence: AF070584
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000584205 ENST00000462733(uc002gsd.1) ENST00000585101 ENST00000302530
    ENST00000474627(uc002gse.1) ENST00000467560 ENST00000496852 ENST00000581698
    ENST00000469327 ENST00000465337 ENST00000488753 ENST00000444058 ENST00000577586
    ENST00000497871(uc010vxf.1)

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate ATPAF2:
    hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmid: ATPAF2 3' UTR sequence
    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AF052185.1 AF070584.1 AK290257.1 AK294487.1 AK296382.1 AY203943.1 BC004114.2 BC032126.2 
    BC128216.1 BC150162.1 

    15 DOTS entries:

    DT.97799331  DT.91683317  DT.115420  DT.120908574  DT.120908575  DT.100728299  DT.95237695  DT.100774697 
    DT.120908607  DT.75102049  DT.95170475  DT.97777981  DT.100743887  DT.40304429  DT.92022121 

    24/181 AceView cDNA sequences (see all 181):

    BQ690271 BX381733 BQ057465 BG168724 BM558942 BM555698 BM468133 AI208992 
    BM561309 BQ691561 CA313434 AI082359 BQ689395 BQ428245 CF527980 AF052185 
    BI905980 BU616506 BC032126 BM725851 AA235550 BM677968 BM504902 F05506 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ATPAF2 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14
    SP1:                                      -     -     -           -     -                 -           -     -               
    SP2:                                -     -     -     -           -     -                 -                                 
    SP3:                                                              -     -                 -                                 
    SP4:                                                                                                                        
    SP5:                                -     -     -     -           -     -           -     -     -     -     -     -         


    ECgene alternative splicing isoforms for ATPAF2

    Expression
    for ATPAF2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATPAF2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACTATGAGCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ATPAF2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ATPAF2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATPAF2

    SOURCE GeneReport for Unigene cluster: Hs.528889

    UniProtKB/Swiss-Prot: ATPF2_HUMAN, Q8N5M1
    Tissue specificity: Widely expressed

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    In Situ
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    Orthologs
    for ATPAF2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ATPAF2 gene from 10/32 species (see all 32)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Atpaf21 , 5 ATP synthase mitochondrial F1 complex assembly factor more1, 5 86.27(n)1
    87.2(a)1    		   11 (37.81 cM)5
    2467821  NM_145427.21  NP_663402.21 
     604006265 
    chicken
    (Gallus gallus)    		 Aves ATPAF21 ATP synthase mitochondrial F1 complex assembly factor more 74.85(n)
    77.22(a)    		   416511  XM_414815.2  XP_414815.1 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    		 --
    		 76(a)
    70(a)
    		 many → 1
    many → 1
    		 AAWZ02039086(6473-9532)
    GL343977.1(42817-50004)
    African clawed frog
    (Xenopus laevis)    		 Amphibia CA982826.12   -- 75.93(n)    CA982826.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.47262 Transcribed sequence with weak similarity to protein more 68.83(n)    AL922862.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta l(2)k145051 lethal (2) k14505 53.59(n)
    43.46(a)    		   35399  NM_136258.1  NP_610102.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea CELE_Y116A8C.271 Protein Y116A8C.27 42.22(n)
    30.42(a)    		   191004  NM_070628.5  NP_503029.2 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes ATP121 Atp12p 41(n)
    28.32(a)    		   853259   NP_012355.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G406601 ATP synthase mitochondrial F1 complex assembly factor more 42.86(n)
    32.9(a)    		   834066  NM_123431.3  NP_198882.1 
    rice
    (Oryza sativa)    		 Liliopsida Os07g06440001 hypothetical protein 41.89(n)
    27.55(a)    		   4344085  NM_001066980.1  NP_001060445.1 


    ENSEMBL Gene Tree for ATPAF2 (if available)
    TreeFam Gene Tree for ATPAF2 (if available) 

    Paralogs
    for ATPAF2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for ATPAF2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/271 NCBI SNPs in ATPAF2 are shown (see all 271)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1048945541,2
    		Cpathogenic18491081(-) CTGAGA/TGGGAT 2 R W mis10--------
    rs782923121,2
    		C,F,--17674903(+) CAGAAA/CGTAGC 1 -- ds50011Minor allele frequency- C:0.06WA 118
    rs620735691,2
    		--17674990(+) ATGCAC/TATCAG 1 -- ds50011Minor allele frequency- T:0.01NA 120
    rs779800721,2
    		C,F,--17675190(+) CAAATA/GGAGTT 1 -- ut311Minor allele frequency- G:0.05WA 118
    rs1137032031,2
    		--17675908(+) CACATG/AAGACA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs116528191,2
    		C,F,H,--17675944(+) AACACC/TCAGGT 1 -- int114Minor allele frequency- T:0.05NS EA NA WA 1890
    rs1132608171,2
    		--17675983(+) ATCCCA/GGCACT 1 -- int13Minor allele frequency- G:0.05CSA WA EA 240
    rs612824701,2
    		C,--17676193(+) GATCAC/TACCGC 1 -- int11Minor allele frequency- T:0.50WA 2
    rs116530631,2
    		C,H--17676483(+) CACTTC/TCTCCC 1 -- int16Minor allele frequency- T:0.00NS EA NA 418
    rs778468091,2
    		--17676548(+) AGTGCC/TCCCCA 1 -- int13Minor allele frequency- T:0.07CSA WA 121

    HapMap Linkage Disequilibrium report for ATPAF2 (17880723 - 17942523 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ATPAF2
         1 Inversion: 0495
    Human Gene Mutation Database (HGMD): ATPAF2

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    Disorders / Diseases
    for ATPAF2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ATPAF2 for disorders           About GeneDecksing

    OMIM gene information: 608918   
    OMIM disorders: 604273  
    UniProtKB/Swiss-Prot: ATPF2_HUMAN, Q8N5M1
  • Defects in ATPAF2 are a cause of mitochondrial complex V deficiency nuclear type 1 (MC5DN1) [MIM:604273]. A
    • mitochondrial disorder with heterogeneous clinical manifestations including dysmorphic features, psychomotor
    retardation, hypotonia, growth retardation, cardiomyopathy, enlarged liver, hypoplastic kidneys and elevated lactate
    levels in urine, plasma and cerebrospinal fluid

    7 diseases for ATPAF2:    About MalaCards
    atp synthase deficiency, nuclear-encoded    smith-magenis syndrome    mitochondrial complex v deficiency    complex v
    lactic acidosis    hypotonia    dementia

    Human Genome Epidemiology (HuGE) Navigator: ATPAF2 (2 documents)

    Export disorders for ATPAF2 gene to outside databases

    Publications
    for ATPAF2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATPAF2 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with ATPAF2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Atp11p and Atp12p are assembly factors for the F(1)-ATPase in human mitochondria. (PubMed id 11410595)1, 2, 3 Wang Z.-G.... Ackerman S.H. (2001)
    2. Respiratory chain complex V deficiency due to a mutation in the assembly gene ATP12. (PubMed id 14757859)1, 2 De Meirleir L.... Van Coster R. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse. (PubMed id 11997338)1, 3 Bi W....Lupski J.R. (2002)
    5. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    8. Defining the pathogenesis of the human Atp12p W94R mu tation using a Saccharomyces cerevisiae yeast model. (PubMed id 19933271)1 Meulemans A....Ackerman S.H. (2010)
    9. Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk. (PubMed id 20167577)1 Reynolds C.A....Prince J.A. (2010)
    10. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)

    External Searches for ATPAF2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    Genome Databases showing ATPAF2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 91647 HGNC: 18802 AceView: ATPAF2 Ensembl:ENSG00000171953 euGenes: HUgn91647
    ECgene: ATPAF2 H-InvDB: ATPAF2

    Other Databases showing ATPAF2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ATPAF2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATPAF2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ATPAF2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ATPAF2 gene:
    Search GeneIP for patents involving ATPAF2

    GeneCards and IP:
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