Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATPAF1 Gene

protein-coding   GIFtS: 49
GCID: GC01M047098

ATP synthase mitochondrial F1 complex assembly factor 1

 Explore 1 disease affiliated with
ATPAF1 via our new
 Human Malady Compendium 
Biological research products
for ATPAF1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
ATP Synthase Mitochondrial F1 Complex Assembly Factor 11 2     ATP11p2
ATP111 2 3     Homolog Of Yeast ATP112
Atp11p1     ATP11 Homolog3
FLJ223511     

External Ids:    HGNC: 188031   Entrez Gene: 647562   Ensembl: ENSG000001234727   OMIM: 6089175   UniProtKB: Q5TC123   

Export aliases for ATPAF1 gene to outside databases

Previous GC identifers: GC01M046794 GC01M046055 GC01M046487 GC01M046470 GC01M046812 GC01M046870 GC01M045213


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ATPAF1:
This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds
specifically to the F1 beta subunit and is thought to prevent this subunit from forming nonproductive homooligomers
during enzyme assembly. Alternatively spliced transcript variants have been identified. (provided by RefSeq, Aug 2011)

UniProtKB/Swiss-Prot: ATPF1_HUMAN, Q5TC12
Function: May play an essential role for the assembly of the mitochondrial F1-F0 complex (By similarity)

Gene Wiki entry for ATPAF1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATPAF1 gene promoter:
         POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   NF-kappaB   POU3F2   YY1   Egr-2   POU2F1   POU2F1a   HFH-1   RSRFC4   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ATPAF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATPAF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p33-p32.3   Ensembl cytogenetic band:  1p33   HGNC cytogenetic band: 1p33-p32.3

ATPAF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATPAF1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M047098:  view genomic region     (about GC identifiers)

Start:
47,098,409 bp from pter      End:
47,139,539 bp from pter
Size:
41,131 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ATPF1_HUMAN, Q5TC12 (See protein sequence)
Recommended Name: ATP synthase mitochondrial F1 complex assembly factor 1 precursor  
Size: 328 amino acids; 36437 Da
Subunit: Interacts with ATP5B
Subcellular location: Mitochondrion (By similarity)
Secondary accessions: B1AQW7 B7Z7D6 B7Z7I6 Q9H6E3
Alternative splicing: 3 isoforms:  Q5TC12-1   Q5TC12-2   Q5TC12-3   

Explore the universe of human proteins at neXtProt for ATPAF1: NX_Q5TC12

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q5TC12

  • ATPAF1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001036011.2  NP_001230657.1  NP_001243347.1  NP_073582.3  

    ENSEMBL proteins: 
     ENSP00000460964   ENSP00000431258   ENSP00000436690   ENSP00000436267   ENSP00000330685  
     ENSP00000432771   ENSP00000435732   ENSP00000433437   ENSP00000361005   ENSP00000459167  
     ENSP00000443588  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: ATPAF1
    OriGene Protein Over-expression Lysate: ATPAF1
    OriGene Custom Protein Services for ATPAF1 
    GenScript Custom Purified and Recombinant Proteins Services for ATPAF1
    Novus Biologicals ATPAF1 Protein
    Novus Biologicals ATPAF1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ATPAF1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--


    ATPAF1 for ontologies           About GeneDecksing



    ATPAF1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ATPAF1 
    GenScript Custom Superior Antibodies Services for ATPAF1
    Novus Biologicals ATPAF1 Antibodies
    Search for Antibodies for ATPAF1 at Abcam  
    Uscn Antibodies for ATPAF1
    ThermoFisher Antibodies for ATPAF1

    Assay Products for ATPAF1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ATPAF1
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ATPAF1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ATPAF1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR010591 ATP11

    Graphical View of Domain Structure for InterPro Entry Q5TC12

    ProtoNet protein and cluster: Q5TC12

    UniProtKB/Swiss-Prot: ATPF1_HUMAN, Q5TC12
    Similarity: Belongs to the ATP11 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ATPF1_HUMAN, Q5TC12
    Function: May play an essential role for the assembly of the mitochondrial F1-F0 complex (By similarity)

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 2): ATPAF1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ATPAF1
    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate ATPAF1 (see all 48):
    hsa-miR-361-5p hsa-let-7d hsa-miR-4272 hsa-miR-128 hsa-miR-342-3p hsa-miR-374a* hsa-let-7g hsa-miR-124
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATPAF1 (see all 7)
    OriGene shRNA RFP: ATPAF1
    OriGene siRNA: ATPAF1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATPAF1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ATPAF1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATPAF1 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATPAF1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): ATPAF1 (NM_022745)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ATPAF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATPAF1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ATPAF1
    Search LifeMap BioReagents cell lines for ATPAF1

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATPAF1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11410595


    ATPAF1 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATPAF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/26 Interacting proteins for ATPAF1 (Q5TC122, 3 ENSP000003610054) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATP5BP065763, ENSP000002620304I2D: score=2 STRING: ENSP00000262030
    ATP5A1P257053, ENSP000002820504I2D: score=1 STRING: ENSP00000282050
    BAXQ078122, ENSP000002932884MINT-7307171 STRING: ENSP00000293288
    MCL1Q078202MINT-7307171
    ARHGEF10LENSP000003550604STRING: ENSP00000355060
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006461protein complex assembly IEA--


    ATPAF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ATPAF1
    Search CenterWatch for drugs/clinical trials and news about ATPAF1 / ATPF1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ATPAF1 gene (4 alternative transcripts): 
    NM_001042546.2  NM_001243728.1  NM_001256418.1  NM_022745.4  

    Unigene Cluster for ATPAF1:

    ATP synthase mitochondrial F1 complex assembly factor 1
    Hs.100874  [show with all ESTs]
    Unigene Representative Sequence: BC071731
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000576409 ENST00000492233 ENST00000526821 ENST00000529214 ENST00000329231
    ENST00000534216 ENST00000532925 ENST00000474020 ENST00000487193 ENST00000525633
    ENST00000460928 ENST00000371937(uc010omg.2 uc001cqh.3) ENST00000574428(uc001cqi.3)
    ENST00000542495(uc009vyk.3)

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 2): ATPAF1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ATPAF1
    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate ATPAF1 (see all 48):
    hsa-miR-361-5p hsa-let-7d hsa-miR-4272 hsa-miR-128 hsa-miR-342-3p hsa-miR-374a* hsa-let-7g hsa-miR-124
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATPAF1 (see all 7)
    OriGene shRNA RFP: ATPAF1
    OriGene siRNA: ATPAF1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATPAF1
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATPAF1 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATPAF1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): ATPAF1 (NM_022745)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ATPAF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATPAF1 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATPAF1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATPAF1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATPAF1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATPAF1

    Additional cDNA sequence: 

    AF111705.1 AK026004.1 AK296360.1 AK301874.1 AK302090.1 AK310338.1 AK311271.1 BC008498.1 
    BC018781.1 BC071731.1 

    12 DOTS entries:

    DT.95315462  DT.91762163  DT.95315469  DT.100800542  DT.95350987  DT.40198335  DT.100029053  DT.91762152 
    DT.100800543  DT.121329745  DT.40107951  DT.91848685 

    24/722 AceView cDNA sequences (see all 722):

    BM785012 H15451 AA001638 BU684107 CA416295 BQ014827 AU132961 AF111705 
    BM313450 BM981674 AW166981 BE081142 AA255740 BM661611 AA680159 BQ581691 
    AI470453 CA435345 CR606100 AI523115 CR601689 AL120413 BM994008 AI128449 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ATPAF1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b
    SP1:                          -                             -                           
    SP2:                          -                             -     -     -               
    SP3:                          -                                                         
    SP4:                          -     -     -     -     -     -                           
    SP5:                                                                                    


    ECgene alternative splicing isoforms for ATPAF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATPAF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CACCAGTCAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ATPAF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATPAF1

    SOURCE GeneReport for Unigene cluster: Hs.100874

    UniProtKB/Swiss-Prot: ATPF1_HUMAN, Q5TC12
    Tissue specificity: Weakly expressed in muscle

        SABiosciences Custom PCR Arrays for ATPAF1
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATPAF1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATPAF1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATPAF1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATPAF1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATPAF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ATPAF1 gene from 8/26 species (see all 26)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atpaf11 , 5 ATP synthase mitochondrial F1 complex assembly factor more1, 5 88.7(n)1
    89.08(a)1
      4 (53.06 cM)5
    2306491  NM_181040.41  NP_851383.21 
     1157848125 
    chicken
    (Gallus gallus)
    Aves ATPAF11 ATP synthase mitochondrial F1 complex assembly factor more 69.98(n)
    69.52(a)
      424616  XM_422453.2  XP_422453.1 
    lizard
    (Anolis carolinensis)
    Reptilia ATPAF16
    --
    59(a)
    1 ↔ 1
    GL343249.1(2086836-2102176)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.131922 Transcribed sequence with weak similarity to protein more 71.45(n)    CF590407.1 
    zebrafish
    (Danio rerio)
    Actinopterygii idibd11362 idibd1136 72.04(n)   338110  CK362292.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG103401 CG10340 47.7(n)
    35.34(a)
      42020  NM_142308.1  NP_650565.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G340506
    ATP synthase mitochondrial F1 complex assembly fac...
    25(a)
    1 ↔ 1
    2(14382683-14384279)
    rice
    (Oryza sativa)
    Liliopsida --
    ATP11 protein, expressed
    22(a)
    1 ↔ 1
    2(12335370-12338628)


    ENSEMBL Gene Tree for ATPAF1 (if available)
    TreeFam Gene Tree for ATPAF1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/621 NCBI SNPs in ATPAF1 are shown (see all 621    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1850622251,2
    --47100247(+) ACGCTA/TCTGTA 4 -- ds50010--------
    rs1480658181,2
    --47100313(+) AGAAAG/TGCCAT 4 -- ds50010--------
    rs1882629691,2
    --47100337(+) GACAAC/TAATAC 4 -- ds50010--------
    rs1808847031,2
    --47100376(+) TGTAAA/CCACCG 4 -- ds50010--------
    rs1855368441,2
    --47100429(+) CAAACA/GAAAGA 4 -- ds50010--------
    rs1413895601,2
    --47100490(+) ATTTTG/TCAGTC 4 -- ds50010--------
    rs1887312101,2
    --47100583(+) AAACAC/TTGTAA 4 -- ds50010--------
    rs1383084831,2
    --47100628(+) CCCCAC/TATCCA 4 -- ds50010--------
    rs1156453751,2
    F,--47100800(+) AAAAGC/TGGGTG 4 -- ut311Minor allele frequency- T:0.02WA 118
    rs1428977971,2
    --47100858(+) AACTAC/TACCTG 4 -- ut310--------

    HapMap Linkage Disequilibrium report for ATPAF1 (47098409 - 47139539 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ATPAF1
         1 Indel: 58391

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATPAF1
    DNA2.0 Custom Variant and Variant Library Synthesis for ATPAF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ATPAF1 for disorders           About GeneDecksing

    OMIM gene information: 608917    OMIM disorders: --

    1 disease for ATPAF1:    About MalaCards
    asthma

    Human Genome Epidemiology (HuGE) Navigator: ATPAF1 (2 documents)

    Export disorders for ATPAF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATPAF1 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with ATPAF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Atp11p and Atp12p are assembly factors for the F(1)-ATPase in human mitochondria. (PubMed id 11410595)1, 2, 3 Wang Z.-G.... Ackerman S.H. (2001)
    2. Differential expression of ATPAF1 and ATPAF2 genes encoding F(1)- ATPase assembly proteins in mouse tissues. (PubMed id 12965202)1, 2 Pickova A.... Houstek J. (2003)
    3. Identification of ATPAF1 as a novel candidate gene fo r asthma in children. (PubMed id 21696813)1 Schauberger E.M....Wills-Karp M. (2011)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    7. OGFOD1, a member of the 2-oxoglutarate and iron depen dent dioxygenase family, functions in ischemic signaling. (PubMed id 20579638)1 Saito K....Matsushita M. (2010)
    8. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64756 HGNC: 18803 AceView: ATPAF1andKIAA0494 Ensembl:ENSG00000123472 euGenes: HUgn64756
    ECgene: ATPAF1 H-InvDB: ATPAF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATPAF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ATPAF1 gene:
    Search GeneIP for patents involving ATPAF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for ATPAF1  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATPAF1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATPAF1  
     OriGene Protein Over-expression Lysate for ATPAF1   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for ATPAF1   OriGene 3'-UTR Clone for ATPAF1  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATPAF1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATPAF1  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for ATPAF1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ATPAF1   OriGene Custom Protein Services for ATPAF1  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATPAF1
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATPAF1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATPAF1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATPAF1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATPAF1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATPAF1
     GenScript Custom Purified and Recombinant Proteins Services for ATPAF1 GenScript cDNA clones with any tag delivered in your preferred vector for ATPAF1
     GenScript Custom Assay Services for ATPAF1 GenScript Custom Superior Antibodies Services for ATPAF1
     GenScript Custom overexpressing Cell Line Services for ATPAF1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ATPAF1 promoter
     Search Chromatin IP Primers for ATPAF1
     RT2 qPCR Primer Assay in human, mouse, rat ATPAF1
     Search GNC Networks for ATPAF1
     SABiosciences Custom PCR Arrays for ATPAF1
     Search Tocris compounds for ATPAF1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ATPAF1 antibodies
     ATPAF1 proteins
     ATPAF1 lysates
     Search for Antibodies for ATPAF1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ATPAF1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     ATPAF1 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for ATPAF1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATPAF1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ATPAF1
     Browse SwitchGear Promoter luciferase reporter plasmids for ATPAF1
     ThermoFisher Antibodies for ATPAF1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATPAF1
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ATPAF1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4