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ATP9B Gene

protein-coding   GIFtS: 54
GCID: GC18P076829

ATPase, Class II, Type 9B

(Previous names: ATPase, Class II, type 9B)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ATPase, Class II, Type 9B1 2     hMMR12
ATPIIB2 3     Macrophage MHC Receptor 12
NEO1L2 3     Probable Phospholipid-Transporting ATPase IIB2
EC 3.6.3.13 8     ATPase Class II Type 9B3
ATPASEP2     EC 3.6.38
ATPase Type IV, Phospholipid Transporting (P-Type)2     

External Ids:    HGNC: 135411   Entrez Gene: 3748682   Ensembl: ENSG000001663777   OMIM: 6144465   UniProtKB: O438613   

Export aliases for ATP9B gene to outside databases

Previous GC identifers: GC18P076619 GC18P076855 GC18P074928 GC18P074930 GC18P073459


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ATP9B Gene:
ATP9B (ATPase, class II, type 9B) is a protein-coding gene. Diseases associated with ATP9B include prostate cancer, and malaria. GO annotations related to this gene include phospholipid-translocating ATPase activity and magnesium ion binding. An important paralog of this gene is ATP9A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000018.10  NT_010966.15  NC_018929.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ATP9B gene promoter:
         SREBP-1c   CUTL1   SREBP-1b   CREB   SREBP-1a   deltaCREB   SEF-1 (1)   En-1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATP9B promoter sequence
   Search Chromatin IP Primers for ATP9B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ATP9B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q23   Ensembl cytogenetic band:  18q23   HGNC cytogenetic band: 18q23

ATP9B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP9B gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P076829:  view genomic region     (about GC identifiers)

Start:
76,829,285 bp from pter      End:
77,138,283 bp from pter
Size:
308,999 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ATP9B_HUMAN, O43861 (See protein sequence)
Recommended Name: Probable phospholipid-transporting ATPase IIB  
Size: 1147 amino acids; 129304 Da
Caution: It is uncertain whether Met-1 or Met-53 is the initiator
Secondary accessions: O60872 Q08AD8 Q08AD9
Alternative splicing: 2 isoforms:  O43861-1   O43861-2   

Explore the universe of human proteins at neXtProt for ATP9B: NX_O43861

Explore proteomics data for ATP9B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys481
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ATP9B (O43861) (see all 23)
     WMLTGDK  NDVSMIQ  FLRTSEK  ESVGLTL 


    See ATP9B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_940933.3  
    ENSEMBL proteins: 
     ENSP00000465158   ENSP00000467386   ENSP00000398076   ENSP00000304500   ENSP00000468218  
     ENSP00000466992   ENSP00000465300   ENSP00000464761   ENSP00000468540   ENSP00000465928  
     ENSP00000467935   ENSP00000465269   ENSP00000467657   ENSP00000442794   ENSP00000442015  
    Reactome Protein details: O43861

    ATP9B Human Recombinant Protein Products:

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    ATP9B Assay Products:

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    Cloud-Clone Corp. CLIAs for ATP9B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PATP: ATPases / P-type

    IUPHAR Guide to PHARMACOLOGY protein family classification: ATP9B
    Phospholipid-transporting ATPase

    Selected InterPro protein domains (see all 6):
     IPR008250 ATPase_P-typ_transduc_dom_A
     IPR023214 HAD-like_dom
     IPR006539 ATPase_P-typ_Plipid-transp
     IPR001757 Cation_transp_P_typ_ATPase
     IPR018303 ATPase_P-typ_P_site

    Graphical View of Domain Structure for InterPro Entry O43861

    ProtoNet protein and cluster: O43861

    1 Blocks protein domain: IPB001757 ATPase

    UniProtKB/Swiss-Prot: ATP9B_HUMAN, O43861
    Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily


    ATP9B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ATP9B_HUMAN, O43861
    Catalytic activity: ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2)

         Enzyme Numbers (IUBMB): EC 3.6.3.11 2 EC 3.6.32

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0000287magnesium ion binding IEA--
    GO:0004012phospholipid-translocating ATPase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0015247aminophospholipid transporter activity ----
         
    ATP9B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ATP9B:
     Increased G2M DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ATP9B
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP9B

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP9B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ATP9B_HUMAN, O43861: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Efficient
    exit from the endoplasmic reticulum does not require TMEM30A, nor TMEM30B
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus3
    plasma membrane3
    cytosol1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0005802trans-Golgi network IDA--
    GO:0016021integral component of membrane IEA--
    GO:0048471perinuclear region of cytoplasm IDA--

    ATP9B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ATP9B About    
    See pathways by source

    SuperPathContained pathways About
    1Ion channel transport
    Ion channel transport0.58
    2Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Transmembrane transport of small molecules0.47
    3Ion transport by P-type ATPases
    Ion transport by P-type ATPases

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ATP9B
        Ion transport by P-type ATPases



    ATP9B for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ATP9B
    Interactions:

        Search GeneGlobe Interaction Network for ATP9B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ATP9B (O438613 ENSP000003045004) via UniProtKB, MINT, STRING, and/or I2D (see all 80)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000172850Q9Y3333, ENSP000003728834I2D: score=4 STRING: ENSP00000372883
    ENSG00000224979Q9Y3333, ENSP000004140064I2D: score=4 STRING: ENSP00000414006
    ENSG00000225998Q9Y3333, ENSP000004062804I2D: score=4 STRING: ENSP00000406280
    ENSG00000231502Q9Y3333, ENSP000004033454I2D: score=4 STRING: ENSP00000403345
    ENSG00000236826Q9Y3333, ENSP000004146344I2D: score=4 STRING: ENSP00000414634
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0015914phospholipid transport ----
    GO:0015917aminophospholipid transport ----
    GO:0045332phospholipid translocation NAS--
    GO:0072600establishment of protein localization to Golgi IMP--

    ATP9B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ATP9B

    4 HMDB Compounds for ATP9B    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--
    WaterDihydrogen oxide (see all 2)7732-18-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ATP9B gene: 
    NM_198531.3  

    Unigene Cluster for ATP9B:

    ATPase, class II, type 9B
    Hs.465475  [show with all ESTs]
    Unigene Representative Sequence: NM_198531
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27):
    ENST00000588600 ENST00000586366 ENST00000426216(uc002lmv.1 uc002lmw.1 uc002lmx.3 uc002lna.3 uc010drb.3)
    ENST00000307671(uc002lmy.1 uc002lmz.1) ENST00000586672 ENST00000586722
    ENST00000591464 ENST00000590271 ENST00000591395 ENST00000490210 ENST00000590608
    ENST00000588772 ENST00000585674 ENST00000587878 ENST00000590163 ENST00000591518
    ENST00000589326 ENST00000589732
    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat ATP9B

    Additional mRNA sequence: 

    AB373110.1 AJ006268.1 AK093704.1 AK097757.1 AK127634.1 AK295981.1 AK308291.1 AL096735.1 
    BC037546.1 BC053561.1 BC125219.1 BC125220.1 U78978.1 

    19 DOTS entries:

    DT.75101067  DT.92061061  DT.100693511  DT.95268649  DT.447209  DT.107385  DT.95085752  DT.99930076 
    DT.99942928  DT.100007944  DT.100647278  DT.435342  DT.95123113  DT.95352030  DT.75179587  DT.99941091 
    DT.434145  DT.95347496  DT.95366403 

    2 AceView cDNA sequences:

    AI469459 AK128847 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ATP9B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21
    SP1:                                                                                                                                                
    SP2:                                                                                                                    -                 -         
    SP3:                                                                                                                    -                           
    SP4:                                                                                                                                                
    SP5:              -                                                                                                                                 


    ECgene alternative splicing isoforms for ATP9B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ATP9B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAGAAAATT
    ATP9B Expression
    About this image

    ATP9B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ATP9B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.465475
        Custom PCR Arrays for ATP9B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP9B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ATP9B gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atp9b1 , 5 ATPase, class II, type 9B1, 5 86.74(n)1
    93.19(a)1
      18 (53.90 cM)5
    507711  NM_001201569.11  NP_001188498.11 
     807341435 
    chicken
    (Gallus gallus)
    Aves ATP9B1 ATPase, class II, type 9B 80.66(n)
    91.57(a)
      420817  XM_003640746.2  XP_003640794.1 
    lizard
    (Anolis carolinensis)
    Reptilia ATP9B6
    ATPase, class II, type 9B
    91(a)
    1 ↔ 1
    4(52298853-52460200)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia atp9b1 ATPase, class II, type 9B 77.81(n)
    89.21(a)
      100497381  XM_002936443.2  XP_002936489.2 
    zebrafish
    (Danio rerio)
    Actinopterygii atp9b1 ATPase, class II, type 9B 74.88(n)
    86.53(a)
      568160  NM_001045154.1  NP_001038619.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG317291 CG31729 61.03(n)
    64.68(a)
      34736  NM_165038.2  NP_723806.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tat-51 tat-5 57.99(n)
    60.23(a)
      172748  NM_001047200.2  NP_001040665.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NEO1(YIL048W)4
    NEO11
    Putative aminophospholipid translocase (flippase) involved more4
    NEO11
    54.34(n)1
    52.87(a)1
      9(261437-264892)4
    8547631, 4  NP_012216.11, 4 


    ENSEMBL Gene Tree for ATP9B (if available)
    TreeFam Gene Tree for ATP9B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ATP9B gene
    ATP9A2  
    11 SIMAP similar genes for ATP9B using alignment to 14 protein entries:     ATP9B_HUMAN (see all proteins):
    DKFZp686H2093    hMMR1    DKFZp434A042    ATP9A    ATP8A1    DKFZp779H1459
    ATP11B    ATP8B4    ATP8A2    DKFZp434P0831    ATP11A

    ATP9B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ATP9B (see all 7375)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs284022161,2
    --76827407(+) AGAGAC/GAGGAG 1 -- us2k1 trp30--------
    rs1471990961,2
    --76827533(+) GAAGAC/TGGTGT 1 -- us2k10--------
    rs1146403511,2
    C,F--76827668(+) GGTGTT/GGACTG 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1388969811,2
    --76827685(+) AGATGG/TTGTTG 1 -- us2k10--------
    rs1429048181,2
    --76827853(+) TATCAA/GTTGTT 1 -- us2k10--------
    rs1874343701,2
    --76827899(+) GGCTGA/CGAGTG 1 -- us2k10--------
    rs1175587511,2
    C,F--76827908(+) TGAGGT/CAGAGA 1 -- us2k11Minor allele frequency- C:0.02EA 120
    rs1507071801,2
    --76827946(+) GGAGGC/TCATTG 1 -- us2k10--------
    rs1906556101,2
    --76827994(+) TGTATC/TCAGGT 1 -- us2k10--------
    rs1809518861,2
    --76828119(+) GGGAAG/TATCAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ATP9B (76829285 - 77079285 bp, first 250kb of ATP9B)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ATP9B (see all 75):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv820421CNV Deletion20802225
    esv2717626CNV Deletion23290073
    esv1264547CNV Deletion17803354
    esv2717637CNV Deletion23290073
    esv1783371CNV Deletion17803354
    esv2717635CNV Deletion23290073
    esv2662015CNV Deletion23128226
    esv2675984CNV Deletion23128226
    esv1713949CNV Deletion17803354
    esv2199105CNV Deletion18987734

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614446    OMIM disorders: --

    3 diseases for ATP9B:    
    About MalaCards
    prostate cancer    malaria    prostatitis


    ATP9B for disorders           About GeneDecksing


    Export disorders for ATP9B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ATP9B gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with ATP9B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs. (PubMed id 9548971)1, 2, 3 Halleck M.S....Schlegel R.A. (Genome Res. 1998)
    2. DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)1, 2 Nusbaum C.... Lander E.S. (Nature 2005)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Characterization of 16 novel human genes showing high similarity to yeast sequences. (PubMed id 11124703)1, 2 Stanchi F.... Valle G. (Yeast 2001)
    5. Differential expression of putative transbilayer amphipath transporters. (PubMed id 11015572)1, 3 Halleck M.S.... Schlegel R.A. (Physiol. Genomics 1999)
    6. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PubMed id 23535732)1 Eeles R.A....Easton D.F. (Nat. Genet. 2013)
    7. Specific binding of HLA-B44 to human macrophage MHC receptor 1 on monocytes. (PubMed id 22525042)1 Tashiro-Yamaji J.... Yoshida R. (Gene 2012)
    8. ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner. (PubMed id 21914794)2 Takatsu H.... Shin H.W. (J. Biol. Chem. 2011)
    9. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (amp 2011)
    10. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PubMed id 19460752)1 Yeung M.L....Jeang K.T. (J. Biol. Chem. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 374868 HGNC: 13541 AceView: ATP9B.1 Ensembl:ENSG00000166377 euGenes: HUgn374868
    ECgene: ATP9B H-InvDB: ATP9B

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ATP9B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ATP9B gene:
    Search GeneIP for patents involving ATP9B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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