Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATP9B Gene

protein-coding   GIFtS: 54
GCID: GC18P076855

ATPase, class II, type 9B

(Previous names: ATPase, Class II, type 9B )
 Explore 2 diseases affiliated with
ATP9B via our new
 Human Malady Compendium 
Biological research products
for ATP9B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
ATPase, Class II, Type 9B1 2     HMMR11
ATPIIB1 2 3     Macrophage MHC Receptor 12
NEO1L2 3     Probable Phospholipid-Transporting ATPase IIB2
EC 3.6.3.13 8     ATPase Class II Type 9B3
ATPASEP2     EC 3.6.38
ATPase Type IV, Phospholipid Transporting (P-Type)2     

External Ids:    HGNC: 135411   Entrez Gene: 3748682   Ensembl: ENSG000001663777   OMIM: 6144465   UniProtKB: O438613   

Export aliases for ATP9B gene to outside databases

Previous GC identifers: GC18P076619 GC18P074928 GC18P074930 GC18P073459


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NC_018929.1  NT_025028.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATP9B gene promoter:
         SREBP-1c   CUTL1   SREBP-1b   CREB   SREBP-1a   deltaCREB   SEF-1 (1)   En-1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATP9B promoter sequence
   Search SABiosciences Chromatin IP Primers for ATP9B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP9B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q23   Ensembl cytogenetic band:  18q23   HGNC cytogenetic band: 18q23

ATP9B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP9B gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P076855:  view genomic region     (about GC identifiers)

Start:
76,829,285 bp from pter      End:
77,138,283 bp from pter
Size:
308,999 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ATP9B_HUMAN, O43861 (See protein sequence)
Recommended Name: Probable phospholipid-transporting ATPase IIB  
Size: 1147 amino acids; 129304 Da
Subcellular location: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Efficient exit
from the endoplasmic reticulum does not require TMEM30A, nor TMEM30B
Caution: It is uncertain whether Met-1 or Met-53 is the initiator
Secondary accessions: O60872 Q08AD8 Q08AD9
Alternative splicing: 2 isoforms:  O43861-1   O43861-2   

Explore the universe of human proteins at neXtProt for ATP9B: NX_O43861

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O43861

  • 4/23 DME Specific Peptides for ATP9B (O43861) (see all 23)
     WMLTGDK  NDVSMIQ  FLRTSEK  ESVGLTL 

    ATP9B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_940933.3  
    ENSEMBL proteins: 
     ENSP00000465158   ENSP00000467386   ENSP00000398076   ENSP00000304500   ENSP00000468218  
     ENSP00000466992   ENSP00000465300   ENSP00000464761   ENSP00000468540   ENSP00000465928  
     ENSP00000467935   ENSP00000465269   ENSP00000467657   ENSP00000442794   ENSP00000442015  
    Reactome Protein details: O43861
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for ATP9B 
    GenScript Custom Purified and Recombinant Proteins Services for ATP9B
    Novus Biologicals ATP9B Protein
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ATP9B

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0005802trans-Golgi network IDA--
    GO:0016021integral to membrane NAS--
    GO:0048471perinuclear region of cytoplasm IDA--


    ATP9B for ontologies           About GeneDecksing



    ATP9B Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ATP9B 
    GenScript Custom Superior Antibodies Services for ATP9B
    Novus Biologicals ATP9B Antibody
    Search for Antibodies for ATP9B at Abcam  
    Uscn Antibodies for ATP9B
    Search ThermoFisher Antibodies for ATP9B

    Assay Products for ATP9B: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ATP9B
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ATP9B


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ATP9B for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR023306 ATPase_cation_domN
     IPR023299 ATPase_P-typ_cyto_domN
     IPR008250 ATPase_P-typ_transduc_dom_A
     IPR023214 HAD-like_dom
     IPR006539 ATPase_P-typ_Plipid-transp

    Graphical View of Domain Structure for InterPro Entry O43861

    ProtoNet protein and cluster: O43861

    1 Blocks protein family: IPB001757 ATPase

    UniProtKB/Swiss-Prot: ATP9B_HUMAN, O43861
    Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ATP9B_HUMAN, O43861
    Catalytic activity: ATP + H(2)O + phospholipid(side 1) = ADP + phosphate + phospholipid(side 2)

    Enzyme Numbers (IUBMB): EC 3.6.3.11 2 EC 3.6.32

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: ATP9B
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ATP9B
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ATP9B
    SwitchGear 3'UTR luciferase reporter plasmidATP9B 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP9B (see all 6)
    OriGene shRNA RFP: ATP9B
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP9B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ATP9B

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP9B (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP9B
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: ATP9B (NM_198531)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ATP9B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP9B 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ATP9B
    Search LifeMap BioReagents cell lines for ATP9B

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP9B

    Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding IEA--
    GO:0004012phospholipid-translocating ATPase activity IEA--
    GO:0005524ATP binding NAS--
    GO:0015247aminophospholipid transporter activity NAS--
    GO:0015662ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism IEA--


    ATP9B for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for ATP9B:
     Increased G2M DNA content 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Ion channel transport
    Ion channel transport1.00
    Ion transport by P-type ATPases0.32
    2SLC-mediated transmembrane transport
    Transmembrane transport of small molecules0.50

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for ATP9B
        Transmembrane transport of small molecules
    Ion channel transport
    Ion transport by P-type ATPases



    ATP9B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP9B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/34 Interacting proteins for ATP9B (O438613 ENSP000003045004) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    COPAP536213, ENSP000003570484I2D: score=1 STRING: ENSP00000357048
    LSM2Q9Y3333I2D: score=4 
    ZDHHC17Q8IUH53I2D: score=4 
    ABCD2Q9UBJ23I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0015917aminophospholipid transport NAS--
    GO:0045332phospholipid translocation NAS--
    GO:0072600establishment of protein localization to Golgi IMP--


    ATP9B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ATP9B

    4 HMDB Compounds for ATP9B    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--
    WaterDihydrogen oxide (see all 2)7732-18-5--
    Search CenterWatch for drugs/clinical trials and news about ATP9B 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ATP9B gene: 
    NM_198531.3  

    Unigene Cluster for ATP9B:

    ATPase, class II, type 9B
    Hs.465475  [show with all ESTs]
    Unigene Representative Sequence: NM_198531
    18/27 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27):
    ENST00000588600 ENST00000586366 ENST00000426216(uc002lmv.1 uc002lmw.1 uc002lmx.3 uc002lna.3 uc010drb.3)
    ENST00000307671(uc002lmy.1 uc002lmz.1) ENST00000586672 ENST00000586722
    ENST00000591464 ENST00000590271 ENST00000591395 ENST00000490210 ENST00000590608
    ENST00000588772 ENST00000585674 ENST00000587878 ENST00000590163 ENST00000591518
    ENST00000589326 ENST00000589732

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: ATP9B
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ATP9B
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ATP9B
    SwitchGear 3'UTR luciferase reporter plasmidATP9B 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP9B (see all 6)
    OriGene shRNA RFP: ATP9B
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP9B
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP9B (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP9B
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: ATP9B (NM_198531)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ATP9B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP9B 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP9B
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATP9B
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP9B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP9B

    Additional cDNA sequence: 

    AB373110.1 AJ006268.1 AK093704.1 AK097757.1 AK127634.1 AK295981.1 AK308291.1 AL096735.1 
    BC037546.1 BC053561.1 BC125219.1 BC125220.1 U78978.1 

    19 DOTS entries:

    DT.75101067  DT.92061061  DT.100693511  DT.95268649  DT.447209  DT.107385  DT.95085752  DT.99930076 
    DT.99942928  DT.100007944  DT.100647278  DT.435342  DT.95123113  DT.95352030  DT.75179587  DT.99941091 
    DT.434145  DT.95347496  DT.95366403 

    2 AceView cDNA sequences:

    AI469459 AK128847 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ATP9B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21
    SP1:                                                                                                                                                
    SP2:                                                                                                                    -                 -         
    SP3:                                                                                                                    -                           
    SP4:                                                                                                                                                
    SP5:              -                                                                                                                                 


    ECgene alternative splicing isoforms for ATP9B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATP9B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGAGAAAATT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ATP9B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATP9B

    SOURCE GeneReport for Unigene cluster: Hs.465475
        SABiosciences Custom PCR Arrays for ATP9B
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP9B
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATP9B
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP9B
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP9B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP9B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ATP9B gene from 8/29 species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves ATP9B1 ATPase, class II, type 9B 80.71(n)
    91.75(a)
      420817  XM_003640746.1  XP_003640794.1 
    lizard
    (Anolis carolinensis)
    Reptilia ATP9B6
    --
    92(a)
    1 ↔ 1
    4(52333742-52456239)
    zebrafish
    (Danio rerio)
    Actinopterygii atp9b1 ATPase, class II, type 9B 74.88(n)
    86.53(a)
      568160  NM_001045154.1  NP_001038619.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG317291 CG31729 61.82(n)
    65.79(a)
      34736  NM_135790.3  NP_609634.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tat-51 Protein TAT-5 59.04(n)
    61.59(a)
      172748  NM_001047200.1  NP_001040665.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NEO1(YIL048W)4
    NEO11
    Putative aminophospholipid translocase (flippase) involved more4
    Neo1p1
    53.92(n)1
    52.89(a)1
      9(261437-264892)4
    8547631, 4  NP_012216.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ALA26
    phospholipid-translocating ATPase
    25(a)
    possible ortholog
    5(17817028-17823708)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    phospholipid-transporting ATPase 2, putative, expr...
    phospholipid-transporting ATPase 2, putative, expr...
    30(a)
    25(a)
    possible ortholog
    possible ortholog
    4(16671326-16684592)
    11(14359856-14381249)


    ENSEMBL Gene Tree for ATP9B (if available)
    TreeFam Gene Tree for ATP9B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ATP9B gene
    ATP9A2  
    12 SIMAP similar genes for ATP9B using alignment to 15 protein entries:     ATP9B_HUMAN (see all proteins):
    DKFZp686H2093    hMMR1    DKFZp434A042    ATP9A    ATP8A1    DKFZp779H1459
    ATP11B    ATP8B4    ATP8A2    DKFZp434P0831    ATP11A    ATP8B1

    ATP9B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6168 NCBI SNPs in ATP9B are shown (see all 6168    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs360846231,2
    C--73474929(+) TTTAC-/AAAAAA 1 -- int10--------
    rs1118087411,2
    C,F--73729780(+) GACCTC/TGTTGA 1 -- int12Minor allele frequency- T:0.50NA WA 4
    rs1125995701,2
    C,F--73729920(+) TTGCCG/AACACA 1 -- int12Minor allele frequency- A:0.50NA WA 4
    rs1124811041,2
    C,F--73729955(+) GTAGCG/ATGACC 1 -- int12Minor allele frequency- A:0.50NA WA 4
    rs1131336291,2
    --73734256(+) AGCACA/GTGCTT 1 -- int12Minor allele frequency- G:0.08CSA WA 120
    rs1132245801,2
    --73734348(+) TCAGCG/ACACAG 1 -- int12Minor allele frequency- A:0.04CSA WA 119
    rs284022161,2
    --76827407(+) AGAGAC/GAGGAG 1 -- us2k1 trp30--------
    rs1471990961,2
    --76827533(+) GAAGAC/TGGTGT 1 -- us2k10--------
    rs1146403511,2
    C,F,--76827668(+) GGTGTT/GGACTG 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1388969811,2
    --76827685(+) AGATGG/TTGTTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ATP9B (76829285 - 77079285 bp, first 250kb of ATP9B)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 45 variations for ATP9B
         15/21 CNVs (see all 21): 102741 89014 5927 78007 73216 73215 43310 78002 102743 23548 78005 73218 73219 61652 89013
         15/24 Indels (see all 24): 78010 102744 26147 11994 45707 45709 26142 102742 60268 11997 78012 89017 89016 11995 73217

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP9B
    DNA2.0 Custom Variant and Variant Library Synthesis for ATP9B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ATP9B for disorders           About GeneDecksing

    OMIM gene information: 614446    OMIM disorders: --

    2 diseases for ATP9B:    About MalaCards
    hermaphroditism    malaria


    Export disorders for ATP9B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATP9B gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ATP9B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs. (PubMed id 9548971)1, 2, 3 Halleck M.S....Schlegel R.A. (1998)
    2. DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)1, 2 Nusbaum C.... Lander E.S. (2005)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Characterization of 16 novel human genes showing high similarity to yeast sequences. (PubMed id 11124703)1, 2 Stanchi F.... Valle G. (2001)
    5. Differential expression of putative transbilayer amphipath transporters. (PubMed id 11015572)1, 3 Halleck M.S.... Schlegel R.A. (1999)
    6. Specific binding of HLA-B44 to human macrophage MHC receptor 1 on monocytes. (PubMed id 22525042)1 Tashiro-Yamaji J.... Yoshida R. (2012)
    7. ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner. (PubMed id 21914794)2 Takatsu H.... Shin H.W. (2011)
    8. Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 374868 HGNC: 13541 AceView: ATP9B.1 Ensembl:ENSG00000166377 euGenes: HUgn374868
    ECgene: ATP9B H-InvDB: ATP9B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATP9B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ATP9B gene:
    Search GeneIP for patents involving ATP9B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for ATP9B  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP9B   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP9B  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     Browse OriGene siRNAs   OriGene 3'-UTR Clone for ATP9B  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP9B   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP9B  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ATP9B   OriGene Custom Protein Services for ATP9B  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATP9B
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP9B
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP9B
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP9B
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP9B
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP9B
     GenScript Custom Purified and Recombinant Proteins Services for ATP9B GenScript cDNA clones with any tag delivered in your preferred vector for ATP9B
     GenScript Custom Assay Services for ATP9B GenScript Custom Superior Antibodies Services for ATP9B
     GenScript Custom overexpressing Cell Line Services for ATP9B CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ATP9B promoter
     Search Chromatin IP Primers for ATP9B
     RT2 qPCR Primer Assay in human, mouse, rat ATP9B
     Search GNC Networks for ATP9B
     SABiosciences Custom PCR Arrays for ATP9B
     Search Tocris compounds for ATP9B
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ATP9B antibodies
     ATP9B proteins
     Search for Antibodies for ATP9B at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ATP9B
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     ATP9B Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for ATP9B
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP9B
     SwitchGear 3'UTR luciferase reporter plasmids for ATP9B
     SwitchGear Promoter luciferase reporter plasmids for ATP9B
     Search ThermoFisher Antibodies for ATP9B
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP9B
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ATP9B gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4