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ATP9A Gene

protein-coding   GIFtS: 57
GCID: GC20M050213

ATPase, Class II, Type 9A

(Previous names: ATPase, Class II, type 9A)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ATPase, Class II, Type 9A1 2     Probable Phospholipid-Transporting ATPase IIA2
ATPIIA2 3     KIAA06113
EC 3.6.3.13 8     ATPase Class II Type 9A3
ATPase Type IV, Phospholipid-Transporting (P-Type),(Putative)2     EC 3.6.38
Phospholipid-Transporting ATPase IIA2     

External Ids:    HGNC: 135401   Entrez Gene: 100792   Ensembl: ENSG000000547937   OMIM: 6091265   UniProtKB: O751103   

Export aliases for ATP9A gene to outside databases

Previous GC identifers: GC20M049936 GC20M050851 GC20M050898 GC20M049646 GC20M046960


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ATP9A Gene:
ATP9A (ATPase, class II, type 9A) is a protein-coding gene. GO annotations related to this gene include phospholipid-translocating ATPase activity and magnesium ion binding. An important paralog of this gene is ATP9B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NC_018931.2  NT_011362.11  
Regulatory elements:
   Regulatory transcription factor binding sites in the ATP9A gene promoter:
         HOXA9   HOXA9B   MEF-2   STAT1beta   STAT1alpha   MEF-2A   STAT3   Meis-1a   aMEF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATP9A promoter sequence
   Search Chromatin IP Primers for ATP9A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ATP9A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.2   Ensembl cytogenetic band:  20q13.2   HGNC cytogenetic band: 20q13.2

ATP9A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP9A gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M050213:  view genomic region     (about GC identifiers)

Start:
50,213,053 bp from pter      End:
50,385,173 bp from pter
Size:
172,121 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ATP9A_HUMAN, O75110 (See protein sequence)
Recommended Name: Probable phospholipid-transporting ATPase IIA  
Size: 1047 amino acids; 118583 Da
Sequence caution: Sequence=BAD18775.1; Type=Erroneous initiation; Sequence=CAI18889.1; Type=Erroneous gene model
prediction; Sequence=CAI19203.1; Type=Erroneous gene model prediction; Sequence=CAI22924.1; Type=Erroneous gene
model prediction;
Secondary accessions: E1P5Y3 E1P5Y4 Q5TFW5 Q5TFW6 Q5TFW9 Q6ZMF3 Q9NQK6 Q9NQK7
Alternative splicing: 2 isoforms:  O75110-1   O75110-2   

Explore the universe of human proteins at neXtProt for ATP9A: NX_O75110

Explore proteomics data for ATP9A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys48, Lys404, Lys765, Lys822
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ATP9A (O75110) (see all 20)
     WMLTGDK  NDVSMIQ  FLRTSEK  DKTGTLT 


    See ATP9A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006036.1  
    ENSEMBL proteins: 
     ENSP00000309086   ENSP00000342481   ENSP00000385875  
    Reactome Protein details: O75110

    ATP9A Human Recombinant Protein Products:

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    Search eBioscience for ELISAs for ATP9A 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PATP: ATPases / P-type

    IUPHAR Guide to PHARMACOLOGY protein family classification: ATP9A
    Phospholipid-transporting ATPase

    Selected InterPro protein domains (see all 6):
     IPR008250 ATPase_P-typ_transduc_dom_A
     IPR023214 HAD-like_dom
     IPR006539 ATPase_P-typ_Plipid-transp
     IPR001757 Cation_transp_P_typ_ATPase
     IPR018303 ATPase_P-typ_P_site

    Graphical View of Domain Structure for InterPro Entry O75110

    ProtoNet protein and cluster: O75110

    1 Blocks protein domain: IPB001757 ATPase

    UniProtKB/Swiss-Prot: ATP9A_HUMAN, O75110
    Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily


    Find genes that share domains with ATP9A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ATP9A_HUMAN, O75110
    Catalytic activity: ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2)

         Enzyme Numbers (IUBMB): EC 3.6.3.11 2 EC 3.6.32

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0000287magnesium ion binding IEA--
    GO:0004012phospholipid-translocating ATPase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0019829cation-transporting ATPase activity IEA--
         
    Find genes that share ontologies with ATP9A           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ATP9A:
     Synthetic lethal with Ras 

         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Atp9a):
     no phenotypic analysis 

    Find genes that share phenotypes with ATP9A           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ATP9A
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ATP9A
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    miRNA
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    miRTarBase miRNAs that target ATP9A:
    hsa-mir-335-5p (MIRT018201)

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    Selected qRT-PCR Assays for microRNAs that regulate ATP9A (see all 40):
    hsa-miR-4291 hsa-miR-128 hsa-miR-4275 hsa-miR-374a* hsa-miR-3613-3p hsa-miR-186 hsa-miR-642b hsa-miR-509-3-5p
    SwitchGear 3'UTR luciferase reporter plasmidATP9A 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ATP9A
    Predesigned siRNA for gene silencing in human, mouse, rat ATP9A

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP9A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ATP9A_HUMAN, O75110: Early endosome membrane; Multi-pass membrane protein. Recycling endosome. Golgi apparatus,
    trans-Golgi network membrane. Note=Efficient exit from the endoplasmic reticulum does not require TMEM30A, nor
    TMEM30B
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    golgi apparatus3
    plasma membrane3
    endoplasmic reticulum1
    nucleus1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005769early endosome IDA--
    GO:0005794Golgi apparatus IEA--
    GO:0005802trans-Golgi network IDA--
    GO:0016021integral component of membrane IEA--
    GO:0031901early endosome membrane IEA--

    Find genes that share ontologies with ATP9A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ATP9A About    
    See pathways by source

    SuperPathContained pathways About
    1Ion channel transport
    Ion channel transport0.58
    2Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Transmembrane transport of small molecules0.47
    3Ion transport by P-type ATPases
    Ion transport by P-type ATPases


    Find genes that share SuperPaths with ATP9A           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ATP9A
        Ion transport by P-type ATPases


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ATP9A
    Interactions:

        Search GeneGlobe Interaction Network for ATP9A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ATP9A (O751103 ENSP000003424814) via UniProtKB, MINT, STRING, and/or I2D (see all 58)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ESR1P033723, ENSP000002062494I2D: score=1 STRING: ENSP00000206249
    MON2ENSP000003772524STRING: ENSP00000377252
    SLC35F6ENSP000003455284STRING: ENSP00000345528
    LSM1ENSP000003105964STRING: ENSP00000310596
    LSM5ENSP000004107584STRING: ENSP00000410758
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0015914phospholipid transport ----
    GO:0045332phospholipid translocation NAS--

    Find genes that share ontologies with ATP9A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ATP9A

    Selected HMDB Compounds for ATP9A (see all 2605)    About this table
    CompoundSynonyms CAS #PubMed Ids
    PC(O-16:0/18:2(9Z,12Z))1-hexadecyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine (see all 5)88542-95-412486725
    PE(O-16:1(1Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 15)--12486725
    PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 19)103597-60-012486725
    PE(P-16:0e/0:0)2-azaniumylethyl [(2R)-3-[(E)-hexadec-1-enoxy]-2-hydroxy-propyl] phosphate;1-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine ;LysoPE(dm16:0e) --12486725
    PE(P-16:0e/18:1(9Z))2-(9Z-octadecanoyl)-1-hexadecyl-sn-glycero-3-phosphoethanolamine --12486725
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    PA(16:0/16:0)Dipalmitoylphosphatidic acid (see all 25)7091-44-3--
    PA(16:0/18:1(11Z))PA(16:0/18:1n7) (see all 10)----
    PA(16:0/18:1(9Z))PA(16:0/18:1n9) (see all 10)----



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ATP9A gene: 
    NM_006045.1  

    Unigene Cluster for ATP9A:

    ATPase, class II, type 9A
    Hs.649234  [show with all ESTs]
    Unigene Representative Sequence: NM_006045
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000311637 ENST00000338821(uc002xwf.1 uc002xwg.1 uc010gih.1)
    ENST00000477492 ENST00000402822
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ATP9A (see all 40):
    hsa-miR-4291 hsa-miR-128 hsa-miR-4275 hsa-miR-374a* hsa-miR-3613-3p hsa-miR-186 hsa-miR-642b hsa-miR-509-3-5p
    SwitchGear 3'UTR luciferase reporter plasmidATP9A 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat ATP9A

    Additional mRNA sequence: 

    AB014511.1 AF086357.1 AK025559.1 AK026513.1 AK172802.1 AK299064.1 AL117659.1 BC016044.1 
    BC036759.1 BC043392.1 BC063701.1 BC110591.1 BC110592.1 

    18 DOTS entries:

    DT.80100969  DT.95210395  DT.100010641  DT.100717137  DT.100027445  DT.100782960  DT.91754692  DT.91963772 
    DT.95210391  DT.95378647  DT.100721576  DT.91888607  DT.92424384  DT.95079948  DT.95187506  DT.95210392 
    DT.437227  DT.91646519 

    Selected AceView cDNA sequences (see all 279):

    AA932883 AL043988 AK026513 AI168438 AI023515 AA300427 BM824842 AI361331 
    AA939016 AA164233 BF089116 CR620342 BU677824 CD246091 AI077860 BX343653 
    AL119148 AL043986 AA483783 AL043987 BG257342 BU678414 AA331516 BU633088 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ATP9A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ATP9A Expression
    About this image


    ATP9A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Primitive Streak (Early Embryonic Tissues)    fully expand to see all 4 entries
             Primitive Node Cells Primitive Node
             Notochord
     
     Epiblast (Early Embryo)
             Primitive Node Cells Primitive Node
     
     Cartilage (Muscoskeletal System)
             Notochord Cells Notochord
     
     Brain (Nervous System)
             Cerebral Cortex
    ATP9A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ATP9A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.649234
        Custom PCR Arrays for ATP9A
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ATP9A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP9A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ATP9A gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atp9a1 , 5 ATPase, class II, type 9A1, 5 88.54(n)1
    97.99(a)1
      2 (88.99 cM)5
    119811  NM_015731.31  NP_056546.21 
     1686344385 
    chicken
    (Gallus gallus)
    Aves ATP9A1 ATPase, class II, type 9A 83.04(n)
    96.39(a)
      419345  XM_417508.4  XP_417508.4 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    99(a)
    87(a)
    many → 1
    many → 1
    AAWZ02041473(328-4304)
    GL343226.1(1401643-1501342)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC760682 hypothetical protein MGC76068 78.07(n)    BC063203.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.158352 Transcribed sequence with moderate similarity to protein more 75.94(n)    BM533894.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG317296
    --
    52(a)
    1 → many
    2L(13290006-13301668)
    worm
    (Caenorhabditis elegans)
    Secernentea F02C9.33 ATPase 55(a)   V(3128952-3133076)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NEO16
    Putative aminophospholipid translocase (flippase) ...
    43(a)
    1 → many
    IX(261437-264892) YIL048W


    ENSEMBL Gene Tree for ATP9A (if available)
    TreeFam Gene Tree for ATP9A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ATP9A gene
    ATP9B2  
    13 SIMAP similar genes for ATP9A using alignment to 3 protein entries:     ATP9A_HUMAN (see all proteins):
    DKFZp686H2093    DKFZp434A042    ATP9B    hMMR1    DKFZp779H1459    ATP8A1
    DKFZp434P0831    ATP8A2    ATP11B    ATP11C    ATP8B4    ATP11A
    ATP8B2

    Find genes that share paralogs with ATP9A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ATP9A (see all 4698)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1512810421,2
    --50212833(+) ACCACA/GTTACC 1 -- ds50010--------
    rs1895925431,2
    --50212903(+) GATTAA/CAGACA 1 -- ds50010--------
    rs793962881,2
    C--50212965(+) CTGTTC/TCTATA 1 -- ds50010--------
    rs2008941491,2
    --50212985(+) CTCGA-/TTAAAA 1 -- ds50010--------
    rs731348151,2
    C--50212987(+) TCGATA/TAAAAA 1 -- ds50010--------
    rs756222851,2
    F--50213023(+) GGACCG/ATGTAT 1 -- ds50011Minor allele frequency- A:0.01WA 118
    rs1470533281,2
    --50213052(+) TTATGG/TTTTTC 1 -- ds50010--------
    rs10488781,2
    C,F,A,H--50213253(-) ACTTTT/CTATTA 1 -- ds500132Minor allele frequency- C:0.37MN NS EA NA WA 3452
    rs1173082781,2
    C,F--50213357(+) GCCACG/ACTGGC 1 -- ut311Minor allele frequency- A:0.01NA 120
    rs732656541,2
    C--50213375(+) GAAAGG/TAGAGT 1 -- ut311Minor allele frequency- T:0.50WA 2

    HapMap Linkage Disequilibrium report for ATP9A (50213053 - 50385173 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ATP9A (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2668584CNV Deletion23128226
    nsv513549CNV Insertion21212237
    esv2501264CNV Insertion19546169
    esv268229CNV Insertion20981092
    esv274686CNV Insertion20981092
    esv1250125CNV Insertion17803354
    nsv834004CNV Loss17160897
    nsv527764CNV Loss19592680
    nsv9816CNV Gain18304495
    esv2751917CNV Gain17911159

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ATP9A
    DNA2.0 Custom Variant and Variant Library Synthesis for ATP9A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609126    OMIM disorders: --


    Find genes that share disorders with ATP9A           About GenesLikeMe

    Genetic Association Database (GAD): ATP9A
    Human Genome Epidemiology (HuGE) Navigator: ATP9A (2 documents)

    Export disorders for ATP9A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ATP9A gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with ATP9A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (DNA Res. 1998)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)1, 4 Uhl G.R....Lerman C. (Arch. Gen. Psychiatry 2008)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    6. Differential expression of putative transbilayer amphipath transporters. (PubMed id 11015572)1, 3 Halleck M.S.... Schlegel R.A. (Physiol. Genomics 1999)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    9. Identification of proteins associated with ligand-activated estrogen receptor I+ in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS. (PubMed id 21182205)1 Tarallo R....Weisz A. (Proteomics 2011)
    10. ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner. (PubMed id 21914794)2 Takatsu H.... Shin H.W. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10079 HGNC: 13540 AceView: ATP9A Ensembl:ENSG00000054793 euGenes: HUgn10079
    ECgene: ATP9A H-InvDB: ATP9A

    (According to HUGE)
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    HUGE: KIAA0611

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ATP9A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ATP9A gene:
    Search GeneIP for patents involving ATP9A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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