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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATP9A Gene

protein-coding   GIFtS: 56
GCID: GC20M050213

ATPase, Class II, Type 9A

(Previous names: ATPase, Class II, type 9A)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ATPase, Class II, Type 9A1 2     Probable Phospholipid-Transporting ATPase IIA2
ATPIIA2 3     KIAA06113
EC 3.6.3.13 8     ATPase Class II Type 9A3
ATPase Type IV, Phospholipid-Transporting (P-Type),(Putative)2     EC 3.6.38
Phospholipid-Transporting ATPase IIA2     

External Ids:    HGNC: 135401   Entrez Gene: 100792   Ensembl: ENSG000000547937   OMIM: 6091265   UniProtKB: O751103   

Export aliases for ATP9A gene to outside databases

Previous GC identifers: GC20M049936 GC20M050851 GC20M050898 GC20M049646 GC20M046960


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ATP9A Gene: 
ATP9A (ATPase, class II, type 9A) is a protein-coding gene. Diseases associated with ATP9A include breast cancer, and among its related super-pathways are Ion channel transport and SLC-mediated transmembrane transport. GO annotations related to this gene include phospholipid-translocating ATPase activity and magnesium ion binding. An important paralog of this gene is ATP9B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.2  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATP9A gene promoter:
         HOXA9   HOXA9B   MEF-2   STAT1beta   STAT1alpha   MEF-2A   STAT3   Meis-1a   aMEF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATP9A promoter sequence
   Search SABiosciences Chromatin IP Primers for ATP9A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP9A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.2   Ensembl cytogenetic band:  20q13.2   HGNC cytogenetic band: 20q13.2

ATP9A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP9A gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M050213:  view genomic region     (about GC identifiers)

Start:
50,213,053 bp from pter      End:
50,385,173 bp from pter
Size:
172,121 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ATP9A_HUMAN, O75110 (See protein sequence)
Recommended Name: Probable phospholipid-transporting ATPase IIA  
Size: 1047 amino acids; 118583 Da
Subcellular location: Early endosome membrane; Multi-pass membrane protein. Recycling endosome. Golgi apparatus,
trans-Golgi network membrane. Note=Efficient exit from the endoplasmic reticulum does not require TMEM30A, nor
TMEM30B
Sequence caution: Sequence=BAD18775.1; Type=Erroneous initiation; Sequence=CAI18889.1; Type=Erroneous gene model
prediction; Sequence=CAI19203.1; Type=Erroneous gene model prediction; Sequence=CAI22924.1; Type=Erroneous gene
model prediction;
Secondary accessions: E1P5Y3 E1P5Y4 Q5TFW5 Q5TFW6 Q5TFW9 Q6ZMF3 Q9NQK6 Q9NQK7
Alternative splicing: 2 isoforms:  O75110-1   O75110-2   

Explore the universe of human proteins at neXtProt for ATP9A: NX_O75110

Explore proteomics data for ATP9A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75110

  • 4/20 DME Specific Peptides for ATP9A (O75110) (see all 20)
     WMLTGDK  NDVSMIQ  FLRTSEK  DKTGTLT 

    ATP9A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ATP9A Protein Expression
    REFSEQ proteins: NP_006036.1  
    ENSEMBL proteins: 
     ENSP00000309086   ENSP00000342481   ENSP00000385875  
    Reactome Protein details: O75110
    Human Recombinant Protein Products for ATP9A: 
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    Cloud-Clone Corp. Proteins for ATP9A 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005769early endosome IDA--
    GO:0005794Golgi apparatus IEA--
    GO:0005802trans-Golgi network IDA--
    GO:0016021integral to membrane IEA--
    GO:0031901early endosome membrane IEA--

    ATP9A for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for ATP9A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PATP: ATPases / P-type

    IUPHAR Guide to PHARMACOLOGY protein family classification: ATP9A 
    Phospholipid-transporting ATPase

    5/6 InterPro protein domains (see all 6):
     IPR023299 ATPase_P-typ_cyto_domN
     IPR008250 ATPase_P-typ_transduc_dom_A
     IPR023214 HAD-like_dom
     IPR006539 ATPase_P-typ_Plipid-transp
     IPR001757 Cation_transp_P_typ_ATPase

    Graphical View of Domain Structure for InterPro Entry O75110

    ProtoNet protein and cluster: O75110

    1 Blocks protein domain: IPB001757 ATPase

    UniProtKB/Swiss-Prot: ATP9A_HUMAN, O75110
    Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily


    ATP9A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ATP9A_HUMAN, O75110
    Catalytic activity: ATP + H(2)O + phospholipid(side 1) = ADP + phosphate + phospholipid(side 2)

         Enzyme Numbers (IUBMB): EC 3.6.3.11 2 EC 3.6.32

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0000287magnesium ion binding IEA--
    GO:0004012phospholipid-translocating ATPase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0019829cation-transporting ATPase activity IEA--
         
    ATP9A for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ATP9A:
     Synthetic lethal with Ras 

         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Atp9a):
     no phenotypic analysis 

    ATP9A for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ATP9A 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ATP9A 
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    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidATP9A 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ATP9A About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ion channel transport
    Ion channel transport0.49
    Ion transport by P-type ATPases0.32
    2SLC-mediated transmembrane transport
    Transmembrane transport of small molecules0.50

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for ATP9A
        Transmembrane transport of small molecules
    Ion channel transport
    Ion transport by P-type ATPases



    ATP9A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP9A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/8 Interacting proteins for ATP9A (O751103 ENSP000003424814) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ESR1P033723, ENSP000002062494I2D: score=1 STRING: ENSP00000206249
    LSM5ENSP000004107584STRING: ENSP00000410758
    COPAENSP000003570484STRING: ENSP00000357048
    SURF4ENSP000003610574STRING: ENSP00000361057
    RER1ENSP000003020884STRING: ENSP00000302088
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0015914phospholipid transport ----
    GO:0045332phospholipid translocation NAS--

    ATP9A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ATP9A

    10/2605 HMDB Compounds for ATP9A (see all 2605)    About this table
    CompoundSynonyms CAS #PubMed Ids
    PC(O-16:0/18:2(9Z,12Z))1-hexadecyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine (see all 5)88542-95-412486725
    PE(O-16:1(1Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 15)--12486725
    PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 19)103597-60-012486725
    PE(P-16:0e/0:0)2-azaniumylethyl [(2R)-3-[(E)-hexadec-1-enoxy]-2-hydroxy-propyl] phosphate;1-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine ;LysoPE(dm16:0e) --12486725
    PE(P-16:0e/18:1(9Z))2-(9Z-octadecanoyl)-1-hexadecyl-sn-glycero-3-phosphoethanolamine --12486725
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    PA(16:0/16:0)Dipalmitoylphosphatidic acid (see all 25)7091-44-3--
    PA(16:0/18:1(11Z))PA(16:0/18:1n7) (see all 10)----
    PA(16:0/18:1(9Z))PA(16:0/18:1n9) (see all 10)----

    Search CenterWatch for drugs/clinical trials and news about ATP9A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ATP9A gene: 
    NM_006045.1  

    Unigene Cluster for ATP9A:

    ATPase, class II, type 9A
    Hs.649234  [show with all ESTs]
    Unigene Representative Sequence: NM_006045
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000311637 ENST00000338821(uc002xwf.1 uc002xwg.1 uc010gih.1)
    ENST00000477492 ENST00000402822
    miRNA
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    8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate ATP9A (see all 40):
    hsa-miR-4291 hsa-miR-128 hsa-miR-4275 hsa-miR-374a* hsa-miR-3613-3p hsa-miR-186 hsa-miR-642b hsa-miR-509-3-5p
    SwitchGear 3'UTR luciferase reporter plasmidATP9A 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP9A

    Additional mRNA sequence: 

    AB014511.1 AF086357.1 AK025559.1 AK026513.1 AK172802.1 AK299064.1 AL117659.1 BC016044.1 
    BC036759.1 BC043392.1 BC063701.1 BC110591.1 BC110592.1 

    18 DOTS entries:

    DT.80100969  DT.95210395  DT.100010641  DT.100717137  DT.100027445  DT.100782960  DT.91754692  DT.91963772 
    DT.95210391  DT.95378647  DT.100721576  DT.91888607  DT.92424384  DT.95079948  DT.95187506  DT.95210392 
    DT.437227  DT.91646519 

    24/279 AceView cDNA sequences (see all 279):

    BG257342 CD246091 AI023515 CB118603 AK026513 AA164233 BM480002 BX343653 
    AA910385 BC016044 AL119148 AL043988 AI077860 AI168438 AA331516 BQ719443 
    AI199639 BE378287 BU678414 AA483783 AL043986 AA932883 BF089116 BU633088 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATP9A expression in normal human tissues (normalized intensities)      ATP9A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ATP9A Expression
    About this image


    ATP9A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Primitive Streak (Early Embryonic Tissues)    fully expand to see all 4 entries
             Primitive Node Cells Primitive Node
             Notochord
     
     Epiblast (Early Embryo)
             Primitive Node Cells Primitive Node
     
     Cartilage (Muscoskeletal System)
             Notochord Cells Notochord

    See ATP9A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATP9A

    SOURCE GeneReport for Unigene cluster: Hs.649234
        SABiosciences Custom PCR Arrays for ATP9A
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP9A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP9A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ATP9A gene from 8/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atp9a1 , 5 ATPase, class II, type 9A1, 5 88.54(n)1
    97.99(a)1
      2 (88.99 cM)5
    119811  NM_015731.31  NP_056546.21 
     1686344385 
    chicken
    (Gallus gallus)
    Aves ATP9A1 ATPase, class II, type 9A 83.06(n)
    96.39(a)
      419345  XM_417508.3  XP_417508.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    99(a)
    87(a)
    many → 1
    many → 1
    AAWZ02041473(328-4304)
    GL343226.1(1401643-1501342)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC760682 hypothetical protein MGC76068 78.07(n)    BC063203.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.158352 Transcribed sequence with moderate similarity to protein more 75.94(n)    BM533894.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG317296
    --
    52(a)
    1 → many
    2L(13290006-13301668)
    worm
    (Caenorhabditis elegans)
    Secernentea F02C9.33 ATPase 55(a)   V(3128952-3133076)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NEO16
    Putative aminophospholipid translocase (flippase) ...
    42(a)
    1 → many
    IX(261437-264892)


    ENSEMBL Gene Tree for ATP9A (if available)
    TreeFam Gene Tree for ATP9A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ATP9A gene
    ATP9B2  
    13 SIMAP similar genes for ATP9A using alignment to 3 protein entries:     ATP9A_HUMAN (see all proteins):
    DKFZp686H2093    DKFZp434A042    ATP9B    hMMR1    DKFZp779H1459    ATP8A1
    DKFZp434P0831    ATP8A2    ATP11B    ATP11C    ATP8B4    ATP11A
    ATP8B2

    ATP9A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4698 SNPs in ATP9A are shown (see all 4698)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1512810421,2
    --50212833(+) ACCACA/GTTACC 1 -- ds50010--------
    rs1895925431,2
    --50212903(+) GATTAA/CAGACA 1 -- ds50010--------
    rs793962881,2
    C--50212965(+) CTGTTC/TCTATA 1 -- ds50010--------
    rs2008941491,2
    --50212985(+) CTCGA-/TTAAAA 1 -- ds50010--------
    rs731348151,2
    C--50212987(+) TCGATA/TAAAAA 1 -- ds50010--------
    rs756222851,2
    F--50213023(+) GGACCG/ATGTAT 1 -- ds50011Minor allele frequency- A:0.01WA 118
    rs1470533281,2
    --50213052(+) TTATGG/TTTTTC 1 -- ds50010--------
    rs10488781,2
    C,F,A,H--50213253(-) ACTTTT/CTATTA 1 -- ds500132Minor allele frequency- C:0.37MN NS EA NA WA 3452
    rs1173082781,2
    C,F--50213357(+) GCCACG/ACTGGC 1 -- ut311Minor allele frequency- A:0.01NA 120
    rs732656541,2
    C--50213375(+) GAAAGG/TAGAGT 1 -- ut311Minor allele frequency- T:0.50WA 2

    HapMap Linkage Disequilibrium report for ATP9A (50213053 - 50385173 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/12 variations for ATP9A (see all 12):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2668584CNV Deletion23128226
    nsv513549CNV Insertion21212237
    esv2501264CNV Insertion19546169
    esv268229CNV Insertion20981092
    esv274686CNV Insertion20981092
    esv1250125CNV Insertion17803354
    nsv834004CNV Loss17160897
    nsv527764CNV Loss19592680
    nsv9816CNV Gain18304495
    esv2751917CNV Gain17911159

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609126    OMIM disorders: --

    2 diseases for ATP9A:    About MalaCards
    breast cancer    


    ATP9A for disorders           About GeneDecksing

    Genetic Association Database (GAD): ATP9A
    Human Genome Epidemiology (HuGE) Navigator: ATP9A (2 documents)

    Export disorders for ATP9A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATP9A gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with ATP9A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (1998)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)1, 4 Uhl G.R....Lerman C. (2008)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    6. Differential expression of putative transbilayer amphipath transporters. (PubMed id 11015572)1, 3 Halleck M.S.... Schlegel R.A. (1999)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    8. Identification of proteins associated with ligand-acti vated estrogen receptor a in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS. (PubMed id 21182205)1 Tarallo R....Weisz A. (2011)
    9. ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner. (PubMed id 21914794)2 Takatsu H.... Shin H.W. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10079 HGNC: 13540 AceView: ATP9A Ensembl:ENSG00000054793 euGenes: HUgn10079
    ECgene: ATP9A H-InvDB: ATP9A

    (According to HUGE)
    About This Section
    HUGE: KIAA0611

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATP9A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ATP9A gene:
    Search GeneIP for patents involving ATP9A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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