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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATP8B2 Gene

protein-coding   GIFtS: 54
GCID: GC01P154298

ATPase, aminophospholipid transporter, class I, type 8B,...

(Previous names: ATPase, class I, type 8B, member 2 )
 Explore 4 diseases affiliated with
ATP8B2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ATP8B2    

Aliases
for ATP8B2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
ATPase, Aminophospholipid Transporter, Class I, Type 8B, Member 21 2     Phospholipid-Transporting ATPase ID2
ATPID1 2 3 5     Probable Phospholipid-Transporting ATPase ID2
ATPase, Class I, Type 8B, Member 21 2     ATPase Class I Type 8B Member 23
KIAA11371 3     EC 3.6.38
EC 3.6.3.13 8     

External Ids:    HGNC: 135341   Entrez Gene: 571982   Ensembl: ENSG000001435157   OMIM: 6058675   UniProtKB: P981983   

Export aliases for ATP8B2 gene to outside databases

Previous GC identifers: GC01P152118 GC01P150032 GC01P151076 GC01P151518 GC01P151517 GC01P151113 GC01P152564 GC01P125661


Summaries
for ATP8B2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ATP8B2:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of
aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and
phosphatidylethanolamine from one side of a bilayer to another. Alternatively spliced transcript variants encoding
different isoforms have been identified. (provided by RefSeq, Jul 2008)




Genomic Views
for ATP8B2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATP8B2 gene promoter:
         Spz1   POU2F1   Pbx1a   POU2F1a   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ATP8B2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ATP8B2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP8B2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21.3

ATP8B2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP8B2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P154298:  view genomic region     (about GC identifiers)

Start:
 154,298,029 bp from pter      End:
 154,323,783 bp from pter
Size:
 25,755 bases      Orientation:
 plus strand

Proteins
for ATP8B2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: AT8B2_HUMAN, P98198 (See protein sequence)
Recommended Name: Probable phospholipid-transporting ATPase ID  
Size: 1209 amino acids; 137440 Da
Subcellular location: Membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAH30288.1; Type=Erroneous initiation; Sequence=BAB70822.1; Type=Frameshift; Positions=364;
Sequence=BAG65556.1; Type=Erroneous initiation;
Secondary accessions: B4E3P4 Q6NT69 Q7Z486 Q96I43 Q96NQ7
Alternative splicing: 4 isoforms:  P98198-1   P98198-2   P98198-3   P98198-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ATP8B2: NX_P98198

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P98198

    • 4/20 DME Specific Peptides for ATP8B2 (P98198) (see all 20)
     LAIGDGA  TLAIGDG  RNFGFVF  WVLTGDK 

    ATP8B2 Protein expression data from MOPED and PaxDb:    About this image 
    ATP8B2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001005855.1  NP_065185.1  

    ENSEMBL proteins: 
     ENSP00000357472   ENSP00000357475   ENSP00000340448  
    Reactome Protein details: P98198
    Human Recombinant Protein Products for ATP8B2: 
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    Uscn Proteins for ATP8B2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane RCA12880872

    ATP8B2 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for ATP8B2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ATP8B2 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR023306 ATPase_cation_domN
     IPR023299 ATPase_P-typ_cyto_domN
     IPR008250 ATPase_P-typ_transduc_dom_A
     IPR023214 HAD-like_dom
     IPR006539 ATPase_P-typ_Plipid-transp

    Graphical View of Domain Structure for InterPro Entry P98198

    ProtoNet protein and cluster: P98198

    1 Blocks protein family: IPB001757 ATPase

    UniProtKB/Swiss-Prot: AT8B2_HUMAN, P98198
    Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily


    Function
    for ATP8B2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AT8B2_HUMAN, P98198
    Catalytic activity: ATP + H(2)O + phospholipid(side 1) = ADP + phosphate + phospholipid(side 2)

         Enzyme Numbers (IUBMB): EC 3.6.3.11 2 EC 3.6.32

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding IEA--
    GO:0004012phospholipid-translocating ATPase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0015662ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism IEA--
    GO:0016887ATPase activity RCA12880872
         
    ATP8B2 for ontologies           About GeneDecksing


    Animal Models:
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    hsa-miR-330-5p hsa-miR-1914* hsa-miR-218-1* hsa-miR-374a hsa-miR-30d hsa-miR-507 hsa-miR-4267 hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): ATP8B2 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    In Situ Assay
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    Pathways & Interactions
    for ATP8B2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Ion channel transport
    		Ion channel transport1.00
    		Ion transport by P-type ATPases0.32
    2SLC-mediated transmembrane transport
    		Transmembrane transport of small molecules0.50

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for ATP8B2
        Transmembrane transport of small molecules
    Ion channel transport
    Ion transport by P-type ATPases



    ATP8B2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP8B2

    1 Interacting protein for ATP8B2 (P981983) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DNAJC2Q995433I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006200ATP catabolic process RCA12880872
    GO:0006812cation transport IEA--
    GO:0034220ion transmembrane transport TAS--
    GO:0055085transmembrane transport TAS--

    ATP8B2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ATP8B2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ATP8B2

    10/2605 HMDB Compounds for ATP8B2 (see all 2605)    About this table
    CompoundSynonyms CAS #PubMed Ids
    PC(O-16:0/18:2(9Z,12Z))1-hexadecyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine (see all 5)88542-95-412486725
    PE(O-16:1(1Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 15)--12486725
    PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 19)103597-60-012486725
    PE(P-16:0e/0:0)2-azaniumylethyl [(2R)-3-[(E)-hexadec-1-enoxy]-2-hydroxy-propyl] phosphate;1-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine ;LysoPE(dm16:0e) --12486725
    PE(P-16:0e/18:1(9Z))2-(9Z-octadecanoyl)-1-hexadecyl-sn-glycero-3-phosphoethanolamine --12486725
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    PA(16:0/16:0)Dipalmitoylphosphatidic acid (see all 25)7091-44-3--
    PA(16:0/18:1(11Z))PA(16:0/18:1n7) (see all 10)----
    PA(16:0/18:1(9Z))PA(16:0/18:1n9) (see all 10)----
    Search CenterWatch for drugs/clinical trials and news about ATP8B2 / AT8B2 

    Transcripts
    for ATP8B2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ATP8B2 gene (2 alternative transcripts): 
    NM_001005855.1  NM_020452.3  

    Unigene Cluster for ATP8B2:

    ATPase, aminophospholipid transporter, class I, type 8B, member 2
    Hs.435700  [show with all ESTs]
    Unigene Representative Sequence: NM_020452
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368487(uc001few.3) ENST00000368490 ENST00000368489(uc001fex.3)
    ENST00000426445 ENST00000514107 ENST00000505882 ENST00000341822(uc001fey.1)


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    hsa-miR-330-5p hsa-miR-1914* hsa-miR-218-1* hsa-miR-374a hsa-miR-30d hsa-miR-507 hsa-miR-4267 hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): ATP8B2 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AB032963.1 AK304806.1 AL137537.1 AY302537.1 BC007837.2 BC030288.1 BC041573.1 BC063858.1 
    BC069264.1 X58235.1 

    3 DOTS entries:

    DT.95157507  DT.75149140  DT.95204116 

    24/81 AceView cDNA sequences (see all 81):

    BX101039 NM_020452 AB032963 BQ228487 BI861069 AL137537 AW295101 BC063858 
    BC041573 BX441200 BC030288 CA393751 BC069264 CR621246 BU145253 BM712635 
    AY302537 AI800649 BQ940106 BU615851 AK054886 AW003610 AF150357 BQ574927 

    GeneLoc Exon Structure


    Expression
    for ATP8B2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATP8B2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCTGTCTGTG
    ATP8B2 Expression
    About this image

    ATP8B2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    9 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BoneEndochondral Facial BonesBone
    BoneThoracic RibBone
    BrainMedulla OblongataBrain
    LimbAutopodLimb
    LimbStylopodLimb
    LimbZeugopodLimb
    Neural TubeMetencephalonNeural Tube
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ATP8B2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATP8B2

    SOURCE GeneReport for Unigene cluster: Hs.435700

    UniProtKB/Swiss-Prot: AT8B2_HUMAN, P98198
    Tissue specificity: Isoform 3 is ubiquitous, with highest expression in aorta, cerebellum and uterus

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    In Situ
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    Orthologs
    for ATP8B2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ATP8B2 gene from 7/28 species (see all 28)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves ATP8B21 ATPase, class I, type 8B, member 2 83.98(n)
    92.61(a)    		   770035  XM_001233349.2  XP_001233350.2 
    lizard
    (Anolis carolinensis)    		 Reptilia ATP8B26
    		 --
    		 88(a)
    		 1 ↔ 1
    		 GL343805.1(167151-191753)
    zebrafish
    (Danio rerio)    		 Actinopterygii 570461752   -- 80.09(n)    57046175 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG147411 , 3 P-type ATPase3
    CG147411    		 54(a)3
    61.03(n)1
    59.32(a)1    		   87A73
    414691  NM_169450.31  NP_731669.21 
    worm
    (Caenorhabditis elegans)    		 Secernentea T24H7.5b3
    tat-21    		 ATPase3
    Protein TAT-21    		 35(a)
    (best of 2)3
    56.92(n)1
    58.01(a)1    		   II(6234538-6244184)3
    1772561  NM_001028081.11  NP_001023252.11 
    A. gossypii yeast
    (Ashbya gossypii)    		 Saccharomycetes AGOS_AGR120C1 AGR120Cp 48.17(n)
    39.26(a)    		   4623088  NM_211848.1  NP_986786.1 
    rice
    (Oryza sativa)    		 Liliopsida --
    		 phospholipid-transporting ATPase 2, putative, expr...
    		 26(a)
    		 possible ortholog
    		 9(1611177-1614358)


    ENSEMBL Gene Tree for ATP8B2 (if available)
    TreeFam Gene Tree for ATP8B2 (if available) 

    Paralogs
    for ATP8B2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ATP8B2 gene
    ATP11A2  ATP8B12  ATP11B2  ATP8A12  ATP11C2  ATP8B42  ATP8A22  ATP8B32  
    12 SIMAP similar genes for ATP8B2 using alignment to 2 protein entries:     AT8B2_HUMAN (see all proteins):
    ATP8B4    ATP8B1    ATP8A1    ATP8B3    ATP8A2    ATP11A
    ATP11C    ATP11B    ATP10A    ATP10B    ATP10D    ATP9A

    ATP8B2 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for ATP8B2
    PGOHUM00000243365 PGOHUM00000236448


    Genomic Variants
    for ATP8B2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/481 NCBI SNPs in ATP8B2 are shown (see all 481)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs770389761,2
    		C--154296305(+) CTGGTA/GCTGGC 2 -- int1 us2k10--------
    rs1113086761,2
    		--154296561(+) CCCTAC/AGGCAA 2 -- us2k1 int11Minor allele frequency- A:0.50CSA 2
    rs1486878211,2
    		--154296653(+) CCACCC/TTGGGA 2 -- int1 us2k10--------
    rs1422247531,2
    		--154297323(+) CCCTGA/GGGACT 2 -- ut31 us2k10--------
    rs1839088211,2
    		--154297692(+) TTATTC/TACCAC 2 -- ut31 us2k10--------
    rs1510243321,2
    		--154297846(+) GGACGG/TACGTG 2 -- us2k1 ds50010--------
    rs1884598781,2
    		--154298301(+) CACCGA/GGGGCC 3 -- ds5001 us2k1 int10--------
    rs12055911,2
    		C--154298374(+) CGGGTG/TCCCGG 2 -- us2k1 int111Minor allele frequency- T:0.19MN NA WA CSA EA 554
    rs74160101,2
    		C,A,H--154298461(+) GGCGCG/AAGTGC 2 -- us2k1 int16Minor allele frequency- A:0.00NS EA NA 416
    rs284968191,2
    		C,F,H--154298499(+) AGGGGA/GGACCC 2 -- int1 us2k12Minor allele frequency- G:0.23NS NA 286

    HapMap Linkage Disequilibrium report for ATP8B2 (154298029 - 154323783 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ATP8B2: --

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    Disorders / Diseases
    for ATP8B2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ATP8B2 for disorders           About GeneDecksing

    OMIM gene information: 605867    OMIM disorders: --

    4 diseases for ATP8B2:    About MalaCards
    intrahepatic cholestasis    cholestasis    liver disease    pharyngitis

    Human Genome Epidemiology (HuGE) Navigator: ATP8B2 (3 documents)

    Export disorders for ATP8B2 gene to outside databases

    Publications
    for ATP8B2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATP8B2 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with ATP8B2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2, 3 Hirosawa M.... Ohara O. (1999)
    2. FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body. (PubMed id 12880872)1, 2, 9 Harris M.J. and Arias I.M. (2003)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Differential expression of putative transbilayer amphipath transporters. (PubMed id 11015572)1, 3 Halleck M.S.... Schlegel R.A. (1999)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
    8. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)

    External Searches for ATP8B2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    Genome Databases showing ATP8B2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57198 HGNC: 13534 AceView: ATP8B2 Ensembl:ENSG00000143515 euGenes: HUgn57198
    ECgene: ATP8B2 H-InvDB: ATP8B2

    Other Databases showing ATP8B2 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA1137

    Specialized Databases showing ATP8B2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATP8B2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ATP8B2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ATP8B2 gene:
    Search GeneIP for patents involving ATP8B2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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