ATP6V1H Gene
protein-coding GIFtS: 60
GCID: GC08M054678
|
|
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit...(Previous names: ATPase, H+ transporting, lysosomal 50/57kD, V1 subunit...)
| |
Aliases
for ATP6V1H gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H1 2 | | NBP12 3 | | SFD1 2 | | V-ATPase 50/57 KDa Subunits2 3 | | SFDalpha1 2 | | V-ATPase Subunit H2 3 | | SFDbeta1 2 | | CGI-111 | | VMA131 2 | | ATPase, H+ Transporting, Lysosomal 50/57kD, V1 Subunit H1 | | Nef-Binding Protein 12 3 | | MSTP0422 | | Protein VMA13 Homolog2 3 | | V-Type Proton ATPase Subunit H2 | | Vacuolar Proton Pump Subunit H2 3 | | Vacuolar ATP Synthase Subunit H2 | | Vacuolar Proton Pump Subunit SFD2 3 | | Vacuolar ATPase Subunit H2 |
Export aliases for ATP6V1H gene to outside databasesPrevious GC identifers: GC08M053927 GC08M054567 GC08M054351 GC08M054790 GC08M050095 |
Summaries
for ATP6V1H gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ATP6V1H:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification ofintracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes includingprotein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATPbut not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.(provided by RefSeq, May 2012)
UniProtKB/Swiss-Prot: VATH_HUMAN, Q9UI12Function: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of theenzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety ofintracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes inthe vacuolar system (By similarity). Involved in the endocytosis mediated by clathrin-coated pits, required for theformation of endosomes
 summary
for ATP6V1H: H+-ATPase (also known as vacuolar ATPase, V-ATPase) is a enzyme transporter that functions to acidify
intracellular compartments in eukaryotic cells. It is ubiquitously expressed and is present in endomembrane
organelles such as vacuoles, lysosomes, endosomes, the Golgi apparatus, chromaffin granules and coated
vesicles, as well as in the plasma membrane. H+-ATPase is a multisubunit complex composed of two domains.
The V1 domain is responsible for ATP hydrolysis and the V0 domain is responsible for protein translocation.
There are two main mechanisms of regulating H+-ATPase activity; recycling of H+-ATPase-containing vesicles
to and from the plasma membrane and glucose-sensitive assembly/disassembly of the holoenzyme complex. These
transporters play an important role in processes such as receptor-mediated endocytosis, protein degradation
and coupled transport. They have a function in bone reabsorption and mutations in the A3 gene cause
recessive osteopetrosis. Furthermore, H+-ATPases have been implicated in tumor metastasis and regulation of
sperm motility and maturation.
Gene Wiki entry for ATP6V1H
|
Genomic Views
for ATP6V1H gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008183.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ATP6V1H gene promoter:
FOXJ2 (long isoform) HFH-1 Pax-2 FOXJ2 Pax-2a
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATP6V1H
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6V1H |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q11.2 Ensembl cytogenetic band: 8q11.23 HGNC cytogenetic band: 8q11.2ATP6V1H Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M054678: view genomic region
(about GC identifiers)
Start:
|
54,628,115 bp from pter |
End:
|
54,756,118 bp from pter |
Size:
|
128,004 bases |
Orientation:
|
minus strand |
|
Proteins
for ATP6V1H gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VATH_HUMAN, Q9UI12 (See
protein sequence)Recommended Name: V-type proton ATPase subunit H Size: 483 amino acids; 55883 Da
Subunit: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H)attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d). Interacts with HIV-1 Nefprotein and AP2M1
Secondary accessions: B3KMR0 Q6PK44 Q9H3E3 Q9Y300Alternative splicing: 2 isoforms: Q9UI12-1 Q9UI12-2 Explore the universe of human proteins at neXtProt for ATP6V1H: NX_Q9UI12
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UI12
ATP6V1H Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_057025.2 NP_998784.1 NP_998785.1
ENSEMBL proteins: ENSP00000347359 ENSP00000429947 ENSP00000352522 ENSP00000379995 ENSP00000428255 ENSP00000428625 ENSP00000430314 ENSP00000428969 ENSP00000428825 ENSP00000429786 ENSP00000427835 Reactome Protein details: Q9UI12
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ATP6V1H for ontologies About GeneDecksing
ATP6V1H Antibody Products:
Assay Products for ATP6V1H: |
Protein
Domains /
Families
for ATP6V1H gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATP6V1H for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UI12ProtoNet protein and cluster: Q9UI12 1 Blocks protein family: IPB004908 V-ATPase subunit H
UniProtKB/Swiss-Prot: VATH_HUMAN, Q9UI12Similarity: Belongs to the V-ATPase H subunit family |
Function
for ATP6V1H gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: VATH_HUMAN, Q9UI12Function: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of theenzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety ofintracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes inthe vacuolar system (By similarity). Involved in the endocytosis mediated by clathrin-coated pits, required for theformation of endosomes
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1H (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1H (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ATP6V1H (NM_213619) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP6V1H | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V1H |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V1H |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ATP6V1H for ontologies About GeneDecksing
Animal Models:
1 MGI phenotypic allele  for Atp6v1h (no phenotypes)
ATP6V1H for phenotypes About GeneDecksing
|
Pathways & Interactions
for ATP6V1H gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/14 super-pathways (see all 14) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Insulin receptor recycling | | | 2 | Degradation of CD4 | | | 3 | HIV Infection | | | 4 | Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | | | 5 | Disease | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/17 
Reactome Pathways for ATP6V1H (see all 17)
5/8 
Kegg Pathways (Kegg details for ATP6V1H) (see all 8):
ATP6V1H for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP6V1H
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/71 Interacting proteins for ATP6V1H (Q9UI122, 3 ENSP000003525224) via UniProtKB, MINT, STRING, and/or I2D (see all 71)About this table
Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15): About this table
ATP6V1H for ontologies About GeneDecksing
|
Drugs & Compounds
for ATP6V1H gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for ATP6V1H available from Tocris Bioscience About this table
4 HMDB Compounds for ATP6V1H About this table
Search CenterWatch for drugs/clinical trials and news about ATP6V1H / VATH
|
Transcripts
for ATP6V1H gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATP6V1H gene (3 alternative transcripts): NM_015941.3 NM_213619.2 NM_213620.2 Unigene Cluster for ATP6V1H: ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H Hs.491737 [show with all ESTs]Unigene Representative Sequence: NM_01594118/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21): ENST00000355221(uc003xrl.3 uc003xrm.3 uc003xrn.3 uc011ldv.2 uc010lyd.3)
ENST00000518072 ENST00000522159 ENST00000523343 ENST00000520188(uc003xrk.3)
ENST00000359530 ENST00000523899 ENST00000396774 ENST00000524164 ENST00000523426
ENST00000521707 ENST00000521900 ENST00000522849 ENST00000520049 ENST00000521377
ENST00000519588 ENST00000520070 ENST00000521275
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1H (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1H (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): ATP6V1H (NM_213619) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP6V1H | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V1H |
Additional cDNA sequence: AF112204.1 AF113222.1 AF132945.1 AF298777.1 AK022345.1 AK094839.1 AK098305.1 AK303229.1 AK308204.1 BC007421.2 BC007454.2 BC014862.1 BC025275.1 24/27 DOTS entries (see all 27): DT.95369971 DT.445321 DT.100795002 DT.101983911 DT.121481643 DT.100794996 DT.92457039 DT.121481607 DT.121481717 DT.121481680 DT.100795005 DT.87046509 DT.91804093 DT.100794997 DT.101964642 DT.121481655 DT.92457030 DT.100795006 DT.121481618 DT.121481706 DT.121481713 DT.92457066 DT.92457069 DT.95369974 24/394 AceView cDNA sequences (see all 394): BI915625 AK022345 AF113222 BC007454 CR592283 BP343237 BU176724 BM820187 BM511182 BP378199 CB177925 BM556897 CB854794 AA954413 BM473525 BM829389 CR616924 BU189315 AK098305 BQ050933 BC025275 AL548152 NM_015941 AI310989
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ATP6V1H About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ATP6V1H
|
Expression
for ATP6V1H gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATP6V1H expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTGCCTGTT
About this image
See ATP6V1H Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATP6V1H
SOURCE GeneReport for Unigene cluster: Hs.491737
UniProtKB/Swiss-Prot: VATH_HUMAN, Q9UI12Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for ATP6V1H
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6V1H
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATP6V1H | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP6V1H | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP6V1H | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V1H |
Orthologs
for ATP6V1H gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ATP6V1H gene from 9/30 species (see all 30) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Atp6v1h1 , 5 |
ATPase, H+ transporting, lysosomal V1 subunit H1, 5 |
90.9(n)1
98.71(a)1 |
|
1 (1.85 cM)5
1086641 NM_133826.41 NP_598587.21
50831735 |
chicken
(Gallus gallus) |
Aves |
ATP6V1H1 |
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit more |
83.33(n)
95.67(a) |
|
426199 NM_001197326.1 NP_001184255.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ATP6V1H6 |
-- |
82(a) |
1 ↔ 1 |
GL343244.1(1247938-1268341) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.243652 |
Xenopus laevis transcribed sequence with moderate similarity more |
81.06(n) |
|
BI315482.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
atp6v1h2 |
ATPase, H+ transporting, lysosomal, V1 subunit H |
79.12(n) |
|
286779 AF506234.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
VhaSFD1 , 3 |
hydrogen-transporting two-sector ATPase3
Vacuolar H[+]-ATPase SFD subunit1 |
51(a)3
56.62(n)1
56.47(a)1 |
|
36A123
349971 NM_078861.21 NP_523585.21 |
worm
(Caenorhabditis elegans) |
Secernentea |
T14F9.13
vha-151 |
ATPase subunit3
Protein VHA-151 |
51(a)
(best of 2)3
54.82(n)1
53.73(a)1 |
|
X(2273215-2275205)3
1805341 NM_076011.21 NP_508412.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G420501 |
V-type proton ATPase subunit H |
45.85(n)
30.24(a) |
|
823170 NM_114072.3 NP_189791.1 |
rice
(Oryza sativa) |
Liliopsida |
---- |
vacuolar ATP synthase subunit H, putative, express...vacuolar ATP synthase subunit H, putative, express... |
32(a)26(a) |
many → 1many → 1 |
7(21818394-21821395) 7(21815575-21817950) |
ENSEMBL Gene Tree for ATP6V1H (if available)
TreeFam Gene Tree for ATP6V1H (if available) |
Paralogs
for ATP6V1H gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ATP6V1H gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATP6V1H (54628115 - 54756118 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ATP6V1H
1 CNV: 3734 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6V1H |
|
Disorders
/ Diseases
for ATP6V1H gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATP6V1H for disorders About GeneDecksing
OMIM gene information: 608861
OMIM disorders: --
10  diseases for ATP6V1H: About MalaCardsosteopetrosis rheumatoid arthritis cholera colon carcinoma
arthritis tuberculosis immunodeficiency carcinoma
malaria neuronitis
Export disorders for ATP6V1H gene to outside databases
|
Publications
for ATP6V1H gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATP6V1H gene, integrated from 9 sources (see all 46):
(articles sorted by number of sources associating them with ATP6V1H) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4. (PubMed id 9620685)1, 2, 3, 9 Lu X.... Peterlin B.M. (1998)
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery. (PubMed id 12032142)1, 2 Geyer M....Peterlin B.M. (2002)
- Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
- Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. (PubMed id 22360420)1 Martins-de-Souza D....Bahn S. (2012)
|
External Searches for ATP6V1H gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ATP6V1H gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ATP6V1H gene
(According to HUGE)
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Specialized Databases showing ATP6V1H gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for ATP6V1H | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for ATP6V1H gene:
Search GeneIP for patents involving ATP6V1H
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ATP6V1H gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | OriGene Antibodies for ATP6V1H | | OriGene shRNA RFP for ATP6V1H | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP6V1H | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6V1H | | | OriGene Protein Over-expression Lysate for ATP6V1H | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATP6V1H | | OriGene 3'-UTR Clone for ATP6V1H | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1H | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1H | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ATP6V1H | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ATP6V1H | | OriGene Custom Protein Services for ATP6V1H | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATP6V1H | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6V1H | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6V1H | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP6V1H | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP6V1H | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP6V1H |
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 | | | ATP6V1H Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V1H |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V1H |
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