Aliases for ATP6V1E2 Gene
External Ids for ATP6V1E2 Gene
Previous HGNC Symbols for ATP6V1E2 Gene
Previous GeneCards Identifiers for ATP6V1E2 Gene
GeneCards Summary for ATP6V1E2 Gene
ATP6V1E2 (ATPase H+ Transporting V1 Subunit E2) is a Protein Coding gene. Among its related pathways are Insulin receptor recycling and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include proton-transporting ATPase activity, rotational mechanism and hydrogen-exporting ATPase activity, phosphorylative mechanism. An important paralog of this gene is ATP6V1E1.
UniProtKB/Swiss-Prot for ATP6V1E2 Gene
Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity).
H+-ATPase (also known as vacuolar ATPase, V-ATPase) is a enzyme transporter that functions to acidify intracellular compartments in eukaryotic cells. It is ubiquitously expressed and is present in endomembrane organelles such as vacuoles, lysosomes and endosomes.