ATP6V1C2 Gene
protein-coding GIFtS: 57
GCID: GC02P010861
|
|
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2(Previous names: ATPase, H+ transporting, lysosomal 42kD, V1 subunit C isoform...)
| |
Aliases
for ATP6V1C2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C21 2 | | ATPase, H+ Transporting, Lysosomal 42kD, V1 Subunit C Isoform 21 | | ATP6C21 2 | | ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C Isoform 21 | | VMA51 2 | | V-ATPase C2 Subunit2 | | Vacuolar Proton Pump Subunit C 22 3 | | V-Type Proton ATPase Subunit C 22 | | V-ATPase Subunit C 22 3 | | |
Export aliases for ATP6V1C2 gene to outside databasesPrevious GC identifers: GC00U991215 GC02P010914 GC02P010884 GC02P010812 GC02P010779 GC02P010713 |
Summaries
for ATP6V1C2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ATP6V1C2:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification ofeukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellularprocesses as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradientgeneration. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists ofthree A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalyticsite. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: VATC2_HUMAN, Q8NEY4Function: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of thecatalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase isresponsible for acidifying a variety of intracellular compartments in eukaryotic cells
 summary
for ATP6V1C2: H+-ATPase (also known as vacuolar ATPase, V-ATPase) is a enzyme transporter that functions to acidify
intracellular compartments in eukaryotic cells. It is ubiquitously expressed and is present in endomembrane
organelles such as vacuoles, lysosomes, endosomes, the Golgi apparatus, chromaffin granules and coated
vesicles, as well as in the plasma membrane. H+-ATPase is a multisubunit complex composed of two domains.
The V1 domain is responsible for ATP hydrolysis and the V0 domain is responsible for protein translocation.
There are two main mechanisms of regulating H+-ATPase activity; recycling of H+-ATPase-containing vesicles
to and from the plasma membrane and glucose-sensitive assembly/disassembly of the holoenzyme complex. These
transporters play an important role in processes such as receptor-mediated endocytosis, protein degradation
and coupled transport. They have a function in bone reabsorption and mutations in the A3 gene cause
recessive osteopetrosis. Furthermore, H+-ATPases have been implicated in tumor metastasis and regulation of
sperm motility and maturation.
Gene Wiki entry for ATP6V1C2
|
Genomic Views
for ATP6V1C2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005334.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ATP6V1C2 gene promoter:
STAT1 AP-1 ATF-2 STAT1beta LUN-1 Nkx5-1 STAT1alpha E47 Hand1 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATP6V1C2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6V1C2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Ensembl cytogenetic band: 2p25.1 HGNC cytogenetic band: 2p25.1ATP6V1C2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P010861: view genomic region
(about GC identifiers)
Start:
|
10,861,775 bp from pter |
End:
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10,925,236 bp from pter |
Size:
|
63,462 bases |
Orientation:
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plus strand |
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Proteins
for ATP6V1C2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VATC2_HUMAN, Q8NEY4 (See
protein sequence)Recommended Name: V-type proton ATPase subunit C 2 Size: 427 amino acids; 48759 Da
Subunit: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H)attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d)
Sequence caution: Sequence=AAY24069.1; Type=Erroneous gene model prediction;
Secondary accessions: Q96EL8Alternative splicing: 2 isoforms: Q8NEY4-1 Q8NEY4-2 Explore the universe of human proteins at neXtProt for ATP6V1C2: NX_Q8NEY4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NEY4
ATP6V1C2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001034451.1 NP_653184.2
ENSEMBL proteins: ENSP00000272238 ENSP00000371077 Reactome Protein details: Q8NEY4
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
TAS | -- | | GO:0033180 | proton-transporting V-type ATPase, V1 domain |
IEA | -- |
ATP6V1C2 for ontologies About GeneDecksing
ATP6V1C2 Antibody Products:
Assay Products for ATP6V1C2: |
Protein
Domains /
Families
for ATP6V1C2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATP6V1C2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8NEY4ProtoNet protein and cluster: Q8NEY4 1 Blocks protein family: IPB004907 V-ATPase subunit C
UniProtKB/Swiss-Prot: VATC2_HUMAN, Q8NEY4Similarity: Belongs to the V-ATPase C subunit family |
Function
for ATP6V1C2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: VATC2_HUMAN, Q8NEY4Function: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of thecatalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase isresponsible for acidifying a variety of intracellular compartments in eukaryotic cells
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1C2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V1C2 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism |
IEA | -- |
ATP6V1C2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ATP6V1C2:
|
Pathways & Interactions
for ATP6V1C2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Insulin receptor recycling | | | 2 | Disease | | | 3 | Rheumatoid arthritis | | | 4 | Phagosome | | | 5 | IRS-related events | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/9 
Reactome Pathways for ATP6V1C2 (see all 9)
5/7 
Kegg Pathways (Kegg details for ATP6V1C2) (see all 7):
ATP6V1C2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP6V1C2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/57 Interacting proteins for ATP6V1C2 (Q8NEY43 ENSP000002722384) via UniProtKB, MINT, STRING, and/or I2D (see all 57)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006879 | cellular iron ion homeostasis |
TAS | -- | | GO:0008286 | insulin receptor signaling pathway |
TAS | -- | | GO:0015991 | ATP hydrolysis coupled proton transport |
IEA | -- | | GO:0033572 | transferrin transport |
TAS | -- | | GO:0051701 | interaction with host |
TAS | -- |
ATP6V1C2 for ontologies About GeneDecksing
|
Drugs & Compounds
for ATP6V1C2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for ATP6V1C2 available from Tocris Bioscience About this table
4 HMDB Compounds for ATP6V1C2 About this table
Search CenterWatch for drugs/clinical trials and news about ATP6V1C2 / VATC2
|
Transcripts
for ATP6V1C2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATP6V1C2 gene (2 alternative transcripts): NM_001039362.1 NM_144583.3 Unigene Cluster for ATP6V1C2: ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 Hs.580464 [show with all ESTs]Unigene Representative Sequence: AK1254493 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000272238 ENST00000381661(uc002ras.3 uc002rat.3) ENST00000480289
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1C2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1C2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ATP6V1C2 (NM_144583) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP6V1C2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V1C2 |
Additional cDNA sequence: AK125449.1 AK127836.1 AK292952.1 AY039759.1 BC012142.1 23 DOTS entries: DT.91769871 DT.100789657 DT.100886161 DT.100886178 DT.100886149 DT.100886170 DT.40289867 DT.100886160 DT.101985332 DT.91769870 DT.95188926 DT.100844843 DT.121030750 DT.95100594 DT.100692226 DT.100771343 DT.91769888 DT.97819922 DT.100737025 DT.100886179 DT.100886192 DT.40117534 DT.97786999 24/52 AceView cDNA sequences (see all 52): AI221057 AI186630 AI948768 AA935347 AW300332 AJ711872 CB145320 AW571561 BU684270 H63894 BE179297 AI628373 AI632870 BU781836 CD671085 AA298968 CA391385 BX412136 BE042383 AI769407 W74220 D21018 BX417066 AI858459
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ATP6V1C2 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ATP6V1C2
|
Expression
for ATP6V1C2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATP6V1C2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAAATCTCT
About this image
See ATP6V1C2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATP6V1C2
SOURCE GeneReport for Unigene cluster: Hs.580464
UniProtKB/Swiss-Prot: VATC2_HUMAN, Q8NEY4Tissue specificity: Kidney and placenta
SABiosciences Expression via Pathway-Focused PCR Array including ATP6V1C2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6V1C2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATP6V1C2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP6V1C2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP6V1C2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V1C2 |
Orthologs
for ATP6V1C2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ATP6V1C2 gene from 7/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ATP6V1C21 |
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit more |
72.98(n)
77.37(a) |
|
421939 XM_419951.3 XP_419951.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ATP6V1C26 |
-- |
71(a) |
1 ↔ 1 |
1(147363811-147388375) |
zebrafish
(Danio rerio) |
Actinopterygii |
CU695194.16 |
-- |
50(a) |
1 ↔ 1 |
17(52181639-52205532) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Vha446 |
Vacuolar H[+] ATPase 44kD C subunit |
26(a) |
1 → many |
2R(12212318-12224142) |
worm
(Caenorhabditis elegans) |
Secernentea |
vha-116 |
V-type proton ATPase subunit C |
50(a) |
1 → many |
IV(2307815-2314567) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
DET36 |
V-type proton ATPase subunit C |
38(a) |
1 → many |
1(4375515-4378514) |
rice
(Oryza sativa) |
Liliopsida |
-- |
vacuolar ATP synthase subunit C, putative, express... |
36(a) |
1 → many |
5(29484806-29489045) |
ENSEMBL Gene Tree for ATP6V1C2 (if available)
TreeFam Gene Tree for ATP6V1C2 (if available) |
Paralogs
for ATP6V1C2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ATP6V1C2 gene
- ATP6V1C12
1 SIMAP similar gene for ATP6V1C2 using alignment to 1 protein entry: VATC2_HUMAN:ATP6V1C1
ATP6V1C2 for paralogs About GeneDecksing
|
Genomic Variants
for ATP6V1C2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATP6V1C2 (10861775 - 10925236 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ATP6V1C2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6V1C2 |
|
Disorders
/ Diseases
for ATP6V1C2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATP6V1C2 for disorders About GeneDecksing
6  diseases for ATP6V1C2: About MalaCardsosteopetrosis renal tubular acidosis rheumatoid arthritis cholera
arthritis malaria
1 disease from the University of Copenhagen DISEASES database for ATP6V1C2:Renal tubular acidosis Human Genome Epidemiology (HuGE) Navigator: ATP6V1C2 (1 document)
Export disorders for ATP6V1C2 gene to outside databases
|
Publications
for ATP6V1C2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATP6V1C2 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with ATP6V1C2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C, G and d subunits, and their evaluation in autosomal recessive distal renal tubular acidosis. (PubMed id 12384298)1, 2, 3 Smith A.N.... Karet F.E. (2002)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Coupling of rotation and catalysis in F(1)-ATPase rev ealed by single-molecule imaging and manipulation. (PubMed id 17662945)1 Adachi K....Kinosita K. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Structural features and nucleotide-binding capability of the C subunit are integral to the regulation of the eukaryotic V1Vo ATPases. (PubMed id 16042619)1 Gruber G. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. (PubMed id 15203218)1 Fu G.K....Stuve L.L. (2004)
- Neurotransmitter release: the dark side of the vacuolar-H+ATPase. (PubMed id 14597263)1 Morel N. (2003)
- Proton translocation driven by ATP hydrolysis in V-ATPases. (PubMed id 12788495)1 Kawasaki-Nishi S....Forgac M. (2003)
|
External Searches for ATP6V1C2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ATP6V1C2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ATP6V1C2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ATP6V1C2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ATP6V1C2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ATP6V1C2 gene:
Search GeneIP for patents involving ATP6V1C2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ATP6V1C2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for ATP6V1C2 | | OriGene shRNA RFP for ATP6V1C2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP6V1C2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6V1C2 | | | OriGene Protein Over-expression Lysate for ATP6V1C2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATP6V1C2 | | OriGene 3'-UTR Clone for ATP6V1C2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1C2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V1C2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ATP6V1C2 | | OriGene Custom Protein Services for ATP6V1C2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATP6V1C2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6V1C2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6V1C2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP6V1C2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP6V1C2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP6V1C2 |
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 | | | ATP6V1C2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V1C2 |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V1C2 |
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