ATP6V0D1 Gene
protein-coding GIFtS: 60
GCID: GC16M067471
|
|
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1(Previous names: ATPase, H+ transporting, lysosomal (vacuolar proton pump),...)
(Previous symbol: ATP6D)
| |
Aliases
for ATP6V0D1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D11 2 | | V-ATPase AC39 Subunit2 3 | | ATP6D1 2 3 | | V-ATPase Subunit D 12 3 | | VPATPD1 2 3 | | Vma61 | | ATP6DV1 2 | | ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D Isoform 11 | | P391 2 | | VMA62 | | VATX1 2 | | H(+)-Transporting Two-Sector ATPase, Subunit D2 | | ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump), Member D1 2 | | V-ATPase, Subunit D2 | | V-ATPase 40 KDa Accessory Protein2 3 | | V-Type Proton ATPase Subunit D 12 | | Vacuolar Proton Pump Subunit D 12 3 | | P391 2 | | 32 KDa Accessory Protein2 3 | | |
Export aliases for ATP6V0D1 gene to outside databasesPrevious GC identifers: GC16M058166 GC16M067849 GC16M067207 GC16M067248 GC16M066029 GC16M053345 |
Summaries
for ATP6V0D1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ATP6V0D1:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification ofeukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellularprocesses as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradientgeneration. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists ofthree A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATPcatalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of manyof the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. Thisencoded protein is known as the D subunit and is found ubiquitously. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: VA0D1_HUMAN, P61421Function: Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifyinga variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transportprocesses in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity)
 summary
for ATP6V0D1: H+-ATPase (also known as vacuolar ATPase, V-ATPase) is a enzyme transporter that functions to acidify
intracellular compartments in eukaryotic cells. It is ubiquitously expressed and is present in endomembrane
organelles such as vacuoles, lysosomes, endosomes, the Golgi apparatus, chromaffin granules and coated
vesicles, as well as in the plasma membrane. H+-ATPase is a multisubunit complex composed of two domains.
The V1 domain is responsible for ATP hydrolysis and the V0 domain is responsible for protein translocation.
There are two main mechanisms of regulating H+-ATPase activity; recycling of H+-ATPase-containing vesicles
to and from the plasma membrane and glucose-sensitive assembly/disassembly of the holoenzyme complex. These
transporters play an important role in processes such as receptor-mediated endocytosis, protein degradation
and coupled transport. They have a function in bone reabsorption and mutations in the A3 gene cause
recessive osteopetrosis. Furthermore, H+-ATPases have been implicated in tumor metastasis and regulation of
sperm motility and maturation.
Gene Wiki entry for ATP6V0D1
|
Genomic Views
for ATP6V0D1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ATP6V0D1 gene promoter:
CREB deltaCREB
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATP6V0D1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6V0D1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q22.1 Ensembl cytogenetic band: 16q22.1 HGNC cytogenetic band: 16q22ATP6V0D1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M067471: view genomic region
(about GC identifiers)
Start:
|
67,471,917 bp from pter |
End:
|
67,515,140 bp from pter |
Size:
|
43,224 bases |
Orientation:
|
minus strand |
|
Proteins
for ATP6V0D1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VA0D1_HUMAN, P61421 (See
protein sequence)Recommended Name: V-type proton ATPase subunit d 1 Size: 351 amino acids; 40329 Da
Subunit: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H)attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d)
Sequence caution: Sequence=CAA50591.1; Type=Frameshift; Positions=22, 25, 64, 66;
Secondary accessions: P12953 Q02547Explore the universe of human proteins at neXtProt for ATP6V0D1: NX_P61421
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P61421
ATP6V0D1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004682.2
ENSEMBL proteins: ENSP00000290949 ENSP00000463328 ENSP00000393910 ENSP00000441282 ENSP00000457744 ENSP00000457105 ENSP00000455802 ENSP00000455446 ENSP00000456695 ENSP00000455695 ENSP00000457104 Reactome Protein details: P61421
Human Recombinant Protein Products:
Gene Ontology (GO): 5/11 cellular component terms (GO ID links to tree view) (see all 11): About this table
ATP6V0D1 for ontologies About GeneDecksing
ATP6V0D1 Antibody Products:
Assay Products for ATP6V0D1: |
Protein
Domains /
Families
for ATP6V0D1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATP6V0D1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P61421ProtoNet protein and cluster: P61421 UniProtKB/Swiss-Prot: VA0D1_HUMAN, P61421Similarity: Belongs to the V-ATPase V0D/AC39 subunit family |
Function
for ATP6V0D1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: VA0D1_HUMAN, P61421Function: Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifyinga variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transportprocesses in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0D1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0D1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ATP6V0D1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V0D1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V0D1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | 18752060 | | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism |
IEA | -- | | GO:0015078 | hydrogen ion transmembrane transporter activity |
-- | -- | | GO:0032403 | protein complex binding |
IEA | -- |
ATP6V0D1 for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for ATP6V0D1:
Animal Models:
Mouse knock-out Agrp/Atp6v0d1Agrp/tm1Rpa for ATP6V0D1
1 MGI mutant phenotype (inferred from 2 alleles ) (MGI details for Atp6v0d1):
ATP6V0D1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ATP6V0D1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/14 super-pathways (see all 14) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Insulin receptor recycling | | | 2 | Activation of Chaperone Genes by XBP1(S) | | | 3 | Disease | | | 4 | Expression of ATP6VOD1 | | | 5 | Rheumatoid arthritis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/14 
Reactome Pathways for ATP6V0D1 (see all 14)
5/9 
Kegg Pathways (Kegg details for ATP6V0D1) (see all 9):
ATP6V0D1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP6V0D1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/146 Interacting proteins for ATP6V0D1 (P614212, 3 ENSP000002909494) via UniProtKB, MINT, STRING, and/or I2D (see all 146)About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006879 | cellular iron ion homeostasis |
TAS | -- | | GO:0006987 | activation of signaling protein activity involved in unfolded protein response |
TAS | -- | | GO:0007420 | brain development |
IEA | -- | | GO:0008286 | insulin receptor signaling pathway |
TAS | -- | | GO:0015991 | ATP hydrolysis coupled proton transport |
IEA | -- |
ATP6V0D1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ATP6V0D1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for ATP6V0D1 available from Tocris Bioscience About this table
4 HMDB Compounds for ATP6V0D1 About this table
Search CenterWatch for drugs/clinical trials and news about ATP6V0D1 / VA0D1
|
Transcripts
for ATP6V0D1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATP6V0D1 gene: NM_004691.4 Unigene Cluster for ATP6V0D1: ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 Hs.106876 [show with all ESTs]Unigene Representative Sequence: AK12864117 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000568620 ENST00000290949(uc010vjn.1 uc002ete.1 uc010vjo.1)
ENST00000563305 ENST00000565835 ENST00000426604 ENST00000540149 ENST00000567694
ENST00000561852 ENST00000563064 ENST00000564615 ENST00000567170 ENST00000566322
ENST00000564191 ENST00000564788 ENST00000568101 ENST00000561658 ENST00000568298
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0D1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0D1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ATP6V0D1 (NM_004691) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP6V0D1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V0D1 |
Additional cDNA sequence: AK128641.1 AK300570.1 AK301630.1 AK313035.1 BC008861.2 L05087.1 24/26 DOTS entries (see all 26): DT.100848876 DT.451758 DT.100033987 DT.100848890 DT.91769850 DT.100848874 DT.100848878 DT.120709856 DT.120709879 DT.91769847 DT.91827719 DT.95168677 DT.95232048 DT.100848891 DT.120709813 DT.120709833 DT.120709848 DT.120709889 DT.92010857 DT.92016052 DT.100703092 DT.100829581 DT.100848881 DT.120709886 24/496 AceView cDNA sequences (see all 496): BE909017 BQ672560 CR599418 AA720599 BQ881392 CD366809 BU687213 CR599242 AA353924 CR619627 CR602420 AA299165 T28849 AI143286 BE266646 BP338597 CR615039 BM556356 BU153221 AK125522 CR622440 BE266747 BU944156 CR606968
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ATP6V0D1 (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | | | - | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | | | - | | | | - | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | | | - | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ATP6V0D1
|
Expression
for ATP6V0D1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATP6V0D1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAAGGACAG
About this image
See ATP6V0D1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATP6V0D1
SOURCE GeneReport for Unigene cluster: Hs.106876
UniProtKB/Swiss-Prot: VA0D1_HUMAN, P61421Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for ATP6V0D1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6V0D1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATP6V0D1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP6V0D1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP6V0D1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V0D1 |
Orthologs
for ATP6V0D1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ATP6V0D1 gene from 9/34 species (see all 34) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ATP6V0D11 |
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit more |
84.05(n)
96.58(a) |
|
415674 XM_414041.2 XP_414041.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ATP6V0D16 |
-- |
98(a) |
1 ↔ 1 |
GL344971.1(254-6689) |
African clawed frog
(Xenopus laevis) |
Amphibia |
atp6d-prov2 |
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit more |
76.83(n) |
|
BC042233.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb73h072 |
wufb73h07 |
74.91(n) |
|
322811 BC056822.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
VhaAC393
VhaAC39-11 |
proton transport hydrogen-translocating
V-type more3
Vacuolar H[+] ATPase subunit AC39-11 |
81(a)
(best of 2)3
76.68(n)1
81.34(a)1 |
|
3F43
313421 NM_130724.31 NP_570080.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C30F8.23
vha-161 |
vaculolar ATPase3
Protein VHA-161 |
75(a)3
67.83(n)1
75.07(a)1 |
|
I(5080314-5082261)3
1721341 NM_059114.31 NP_491515.21 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
VMA6(YLR447C)4
VMA61 |
Subunit d of the five-subunit V0 integral membrane more4
Vma6p1 |
52.86(n)1
47.34(a)1 |
|
12(1027893-1026856)4
8511681, 4 NP_013552.31 NP_013552.14 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G287101 |
V-type proton ATPase subunit d1 |
55.81(n)
51.45(a) |
|
822502 NM_113791.3 NP_189512.1 |
rice
(Oryza sativa) |
Liliopsida |
Os01g05870001 |
hypothetical protein |
57.82(n)
52.48(a) |
|
4327660 NM_001049964.1 NP_001043429.1 |
ENSEMBL Gene Tree for ATP6V0D1 (if available)
TreeFam Gene Tree for ATP6V0D1 (if available) |
Paralogs
for ATP6V0D1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ATP6V0D1 gene
- ATP6V0D22
1 SIMAP similar gene for ATP6V0D1 using alignment to 12 protein entries: VA0D1_HUMAN (see all proteins):ATP6V0D2
ATP6V0D1 for paralogs About GeneDecksing
|
Genomic Variants
for ATP6V0D1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATP6V0D1 (67471917 - 67515140 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ATP6V0D1
1 CNV: 102315
1 Indel: 45457 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6V0D1 |
|
Disorders
/ Diseases
for ATP6V0D1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATP6V0D1 for disorders About GeneDecksing
OMIM gene information: 607028
OMIM disorders: --
13  diseases for ATP6V0D1: About MalaCardsosteopetrosis renal tubular acidosis transient cerebral ischemia rheumatoid arthritis
cholera arthritis ischemia ataxia
cerebritis schizophrenia tuberculosis malaria
neuronitis
Human Genome Epidemiology (HuGE) Navigator: ATP6V0D1 (3 documents)
Export disorders for ATP6V0D1 gene to outside databases
|
Publications
for ATP6V0D1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATP6V0D1 gene, integrated from 9 sources (see all 36):
(articles sorted by number of sources associating them with ATP6V0D1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and tissue distribution of subunits C, D, and E of the human vacuolar H(+)-ATPase. (PubMed id 8250920)1, 2, 3 van Hille B.... Bilbe G. (1993)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Structure of the VPATPD gene encoding subunit D of the human vacuolar proton ATPase. (PubMed id 11118322)1, 2 Agarwal A.K. and White P.C. (2000)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
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External Searches for ATP6V0D1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing ATP6V0D1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ATP6V0D1 gene
(According to HUGE)
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Specialized Databases showing ATP6V0D1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for ATP6V0D1 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for ATP6V0D1 gene:
Search GeneIP for patents involving ATP6V0D1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ATP6V0D1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ATP6V0D1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP6V0D1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6V0D1 | | | OriGene Protein Over-expression Lysate for ATP6V0D1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATP6V0D1 | | OriGene 3'-UTR Clone for ATP6V0D1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0D1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0D1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ATP6V0D1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ATP6V0D1 | | OriGene Custom Protein Services for ATP6V0D1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATP6V0D1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6V0D1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6V0D1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP6V0D1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP6V0D1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP6V0D1 |
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 | | | ATP6V0D1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V0D1 |
|  |  |  | | | | Search ThermoFisher Antibodies for ATP6V0D1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V0D1 |
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