ATP6V0B Gene
protein-coding GIFtS: 60
GCID: GC01P044440
|
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b(Previous names: ATPase, H+ transporting, lysosomal (vacuolar proton pump)...)
(Previous symbol: ATP6F)
| |
Aliases
for ATP6V0B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B1 2 | | ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit C''1 | | ATP6F1 2 3 5 | | H(+)-Transporting Two-Sector ATPase, Subunit F2 | | HATPL1 2 | | V-ATPase Subunit C''2 | | VMA161 2 | | V-Type Proton ATPase 21 KDa Proteolipid Subunit2 | | Vacuolar Proton Pump 21 KDa Proteolipid Subunit2 3 | | Vacuolar ATP Synthase 21 KDa Proteolipid Subunit2 | | V-ATPase 21 KDa Proteolipid Subunit2 3 | | Vacuolar Proton Pump, 21 KDa Subunit2 | | ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump) 21kD1 | | HATPL1 2 |
Export aliases for ATP6V0B gene to outside databasesPrevious GC identifers: GC01P044278 GC01P043441 GC01P043870 GC01P043853 GC01P044109 GC01P044213 GC01P042556 |
Summaries
for ATP6V0B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ATP6V0B:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification ofeukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellularprocesses as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradientgeneration. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists ofthree A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATPcatalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of manyof the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. Thisencoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternativelyspliced transcript variants that encode different proteins have been found for this gene. (provided by RefSeq, Jul2008)
UniProtKB/Swiss-Prot: VATO_HUMAN, Q99437Function: Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase isresponsible for acidifying a variety of intracellular compartments in eukaryotic cells
 summary
for ATP6V0B: H+-ATPase (also known as vacuolar ATPase, V-ATPase) is a enzyme transporter that functions to acidify
intracellular compartments in eukaryotic cells. It is ubiquitously expressed and is present in endomembrane
organelles such as vacuoles, lysosomes, endosomes, the Golgi apparatus, chromaffin granules and coated
vesicles, as well as in the plasma membrane. H+-ATPase is a multisubunit complex composed of two domains.
The V1 domain is responsible for ATP hydrolysis and the V0 domain is responsible for protein translocation.
There are two main mechanisms of regulating H+-ATPase activity; recycling of H+-ATPase-containing vesicles
to and from the plasma membrane and glucose-sensitive assembly/disassembly of the holoenzyme complex. These
transporters play an important role in processes such as receptor-mediated endocytosis, protein degradation
and coupled transport. They have a function in bone reabsorption and mutations in the A3 gene cause
recessive osteopetrosis. Furthermore, H+-ATPases have been implicated in tumor metastasis and regulation of
sperm motility and maturation.
Gene Wiki entry for ATP6V0B
|
Genomic Views
for ATP6V0B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ATP6V0B gene promoter:
E2F-4 E2F-3a E2F-5 E2F-2 GATA-2 c-Ets-1 FAC1 Ik-2 E2F E2F-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATP6V0B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6V0B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p32.3 Ensembl cytogenetic band: 1p34.1 HGNC cytogenetic band: 1p32.3ATP6V0B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P044440: view genomic region
(about GC identifiers)
Start:
|
44,440,159 bp from pter |
End:
|
44,443,972 bp from pter |
Size:
|
3,814 bases |
Orientation:
|
plus strand |
|
Proteins
for ATP6V0B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VATO_HUMAN, Q99437 (See
protein sequence)Recommended Name: V-type proton ATPase 21 kDa proteolipid subunit Size: 205 amino acids; 21406 Da
Subunit: Interacts with IFITM3 (By similarity)
Subcellular location: Vacuole membrane; Multi-pass membrane protein
Secondary accessions: D3DPY5 Q6IB32Alternative splicing: 2 isoforms: Q99437-1 Q99437-2 (No experimental confirmation available. Gene prediction based on EST data)Explore the universe of human proteins at neXtProt for ATP6V0B: NX_Q99437
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q99437
ATP6V0B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001034546.1 NP_004038.1
ENSEMBL proteins: ENSP00000432994 ENSP00000431605 ENSP00000434729 ENSP00000236067 ENSP00000432754 ENSP00000435396 ENSP00000431375 ENSP00000434094 Reactome Protein details: Q99437
Human Recombinant Protein Products for ATP6V0B:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
ATP6V0B for ontologies About GeneDecksing
ATP6V0B Antibody Products:
Assay Products for ATP6V0B: |
Protein
Domains /
Families
for ATP6V0B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATP6V0B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q99437ProtoNet protein and cluster: Q99437 1 Blocks protein family: IPB000245 Vacuolar ATP synthase 16kD subunit signature
UniProtKB/Swiss-Prot: VATO_HUMAN, Q99437Similarity: Belongs to the V-ATPase proteolipid subunit family |
Function
for ATP6V0B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: VATO_HUMAN, Q99437Function: Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase isresponsible for acidifying a variety of intracellular compartments in eukaryotic cells Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005215 | transporter activity |
TAS | 9653649 | | GO:0015078 | hydrogen ion transmembrane transporter activity |
IEA | -- |
ATP6V0B for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for ATP6V0B:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0B (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0B (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ATP6V0B (NM_004047) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP6V0B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V0B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V0B |
|
Pathways & Interactions
for ATP6V0B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Insulin receptor recycling | | | 2 | Disease | | | 3 | Rheumatoid arthritis | | | 4 | Tuberculosis | | | 5 | Lysosome | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/9 
Reactome Pathways for ATP6V0B (see all 9)
5/8 
Kegg Pathways (Kegg details for ATP6V0B) (see all 8):
ATP6V0B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP6V0B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/67 Interacting proteins for ATP6V0B (Q994373 ENSP000002360674) via UniProtKB, MINT, STRING, and/or I2D (see all 67)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
ATP6V0B for ontologies About GeneDecksing
|
Drugs & Compounds
for ATP6V0B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for ATP6V0B available from Tocris Bioscience About this table
Search CenterWatch for drugs/clinical trials and news about ATP6V0B / VATO
|
Transcripts
for ATP6V0B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATP6V0B gene (2 alternative transcripts): NM_001039457.1 NM_004047.3 Unigene Cluster for ATP6V0B: ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b Hs.596514 [show with all ESTs]Unigene Representative Sequence: BE62079013 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000472505 ENST00000472174(uc001cld.3 uc001cle.3) ENST00000532642
ENST00000236067 ENST00000471859 ENST00000472277 ENST00000461670 ENST00000468183(uc001clf.3)
ENST00000473485 ENST00000496131 ENST00000498208 ENST00000532072 ENST00000498664
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0B (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0B (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ATP6V0B (NM_004047) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP6V0B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V0B |
Additional cDNA sequence: BC000423.2 BC005876.2 BT007151.1 CR456972.1 D89052.1 L05089.1 12 DOTS entries: DT.219596 DT.99982695 DT.97860594 DT.100828184 DT.100828183 DT.219601 DT.121356786 DT.100654749 DT.97860599 DT.100828186 DT.91772781 DT.97860598 24/566 AceView cDNA sequences (see all 566): BQ082755 BI063219 BM766749 BC005876 BU195121 CF127006 BQ061121 BM767142 AI186322 BM764787 BI824134 D81389 BE407238 BM543483 BM831084 W58264 BM766680 BI192768 BU187680 BM767455 AA345739 BQ679818 BQ688326 AW249534
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ATP6V0B (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9a | · | 9b | · | 9c |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | - | | | | | | - | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | - | | | | | | - | | | | | | | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | - | | - | | - | | | | - | | - | | | | | | - | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ATP6V0B
|
Expression
for ATP6V0B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATP6V0B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTGGGGCTG
About this image
See ATP6V0B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATP6V0B
SOURCE GeneReport for Unigene cluster: Hs.596514
UniProtKB/Swiss-Prot: VATO_HUMAN, Q99437Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for ATP6V0B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6V0B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATP6V0B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP6V0B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP6V0B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V0B |
Orthologs
for ATP6V0B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ATP6V0B gene from 9/42 species (see all 42) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ATP6V0B1 |
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit more |
80.98(n)
89.76(a) |
|
424575 XM_003641703.1 XP_003641751.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ATP6V0B6 |
-- |
87(a) |
1 ↔ 1 |
4(108867023-108881444) |
African clawed frog
(Xenopus laevis) |
Amphibia |
CD362016.12 |
-- |
76.84(n) |
|
CD362016.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb33a012 |
wufb33a01 |
78.25(n) |
|
321724 BC058877.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
VhaPPA1-11 , 3 |
hydrogen-transporting two-sector ATPase3
Vacuolar H[+] ATPase subunit PPA1-11 |
63(a)
(best of 2)3
62.3(n)1
64.92(a)1 |
|
88D63
452471 NM_143753.11 NP_652010.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
T01H3.13
vha-41 |
proteolipid protein PPA1 like protein3
Protein VHA-41 |
63(a)3
60.57(n)1
65.05(a)1 |
|
II(7878204-7879374)3
1742721 NM_063258.51 NP_495659.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
VMA16(YHR026W)4
VMA161 |
Subunit c'' of the vacuolar ATPase, which functions more4
Vma16p1 |
54.93(n)1
56.98(a)1 |
|
8(160844-161485)4
8564211, 4 NP_011891.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G256101 |
V-type H+-transporting ATPase 21kDa proteolipid subunit |
59.28(n)
56.96(a) |
|
817101 NM_128119.1 NP_180132.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.205432 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
74.66(n) |
|
AK104951.1 |
ENSEMBL Gene Tree for ATP6V0B (if available)
TreeFam Gene Tree for ATP6V0B (if available) |
Paralogs
for ATP6V0B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ATP6V0B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATP6V0B (44440159 - 44443972 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ATP6V0B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6V0B |
|
Disorders
/ Diseases
for ATP6V0B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATP6V0B for disorders About GeneDecksing
OMIM gene information: 603717
OMIM disorders: --
9  diseases for ATP6V0B: About MalaCardsosteopetrosis visceral leishmaniasis rheumatoid arthritis leishmaniasis
cholera arthritis pneumonia tuberculosis
malaria
1 disease from the University of Copenhagen DISEASES database for ATP6V0B:Cannabis abuse Export disorders for ATP6V0B gene to outside databases
|
Publications
for ATP6V0B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATP6V0B gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with ATP6V0B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of the gene encoding a second proteolipid subunit of human vacuolar H(+)-ATPase (ATP6F). (PubMed id 9653649)1, 2, 3, 9 Nishigori H.... Takeda J. (1998)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Coupling of rotation and catalysis in F(1)-ATPase rev ealed by single-molecule imaging and manipulation. (PubMed id 17662945)1 Adachi K....Kinosita K. (2007)
- Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump. (PubMed id 17576770)1 Lu M....Gluck S.L. (2007)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- Plasmalemmal V-H(+)-ATPases regulate intracellular pH in human lung microvascular endothelial cells. (PubMed id 15249206)1 Rojas J.D....Martinez-Zaguilan R. (2004)
- Structural and functional characterization of two human V-ATPase subunit gene promoters. (PubMed id 12890556)1 Izumi H....Kohno K. (2003)
- Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes. (PubMed id 14580332)1 Smith A.N....Karet F.E. (2003)
- Neurotransmitter release: the dark side of the vacuolar-H+ATPase. (PubMed id 14597263)1 Morel N. (2003)
|
External Searches for ATP6V0B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ATP6V0B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ATP6V0B gene
(According to HUGE)
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Specialized Databases showing ATP6V0B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for ATP6V0B | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for ATP6V0B gene:
Search GeneIP for patents involving ATP6V0B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ATP6V0B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ATP6V0B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP6V0B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6V0B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATP6V0B | | OriGene 3'-UTR Clone for ATP6V0B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6V0B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ATP6V0B | | OriGene Custom Protein Services for ATP6V0B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATP6V0B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6V0B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6V0B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP6V0B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP6V0B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP6V0B |
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 | | | ATP6V0B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6V0B |
|  |  |  |  | | | | ThermoFisher Antibodies for ATP6V0B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6V0B |
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