ATP6AP2 Gene
protein-coding GIFtS: 61
GCID: GC0XP040440
|
|
ATPase, H+ transporting, lysosomal accessory protein 2(Previous names: ATPase, H+ transporting, lysosomal interacting protein...)
(Previous symbol: ATP6IP2)
| |
Aliases
for ATP6AP2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATPase, H+ Transporting, Lysosomal Accessory Protein 21 2 | | ATPase H(+)-Transporting Lysosomal-Interacting Protein 22 3 | | ATP6M8-91 2 3 5 | | ER-Localized Type I Transmembrane Adaptor2 3 | | ATP6IP21 2 3 | | V-ATPase M8.9 Subunit2 3 | | APT6M8-91 2 | | MRXE2 5 | | M8-91 2 | | XMRE2 5 | | ATPase, H+ Transporting, Lysosomal Interacting Protein 21 2 | | MSTP0092 | | Embryonic Liver Differentiation Factor 102 3 | | ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump) Membrane SectorAssociated Protein M8-92 | | Renin/Prorenin Receptor2 3 | | Renin Receptor2 | | Vacuolar ATP Synthase Membrane Sector-Associated Protein M8-92 3 | | Vacuolar Proton ATP Synthase Membrane Sector Associated Protein M8-92 | | ELDF102 3 | | CAPER3 | | N14F2 3 | | ATPase H(+)-Transporting Lysosomal Accessory Protein 23 |
Export aliases for ATP6AP2 gene to outside databasesPrevious GC identifers: GC0XP039284 GC0XP039471 GC0XP040196 GC0XP040325 GC0XP038171 |
Summaries
for ATP6AP2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ATP6AP2:
This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPaseshave fundamental roles in energy conservation, secondary active transport, acidification of intracellularcompartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type)ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein hasbeen found associated with the transmembrane sector of the V-type ATPases. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RENR_HUMAN, O75787Function: Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses byactivating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion toangiotensin I, it may also play a role in the renin-angiotensin system (RAS)
Gene Wiki entry for ATP6AP2
|
Genomic Views
for ATP6AP2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_079573.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ATP6AP2 gene promoter:
STAT1 STAT1beta NF-E2 p45 Gfi-1 STAT1alpha YY1 NF-AT4 SRY HFH-1 NF-E2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATP6AP2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6AP2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.4 Ensembl cytogenetic band: Xp11.4 HGNC cytogenetic band: Xp11.4ATP6AP2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP040440: view genomic region
(about GC identifiers)
Start:
|
40,440,146 bp from pter |
End:
|
40,465,889 bp from pter |
Size:
|
25,744 bases |
Orientation:
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plus strand |
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Proteins
for ATP6AP2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RENR_HUMAN, O75787 (See
protein sequence)Recommended Name: Renin receptor precursor Size: 350 amino acids; 39008 Da
Subunit: Interacts with renin and the vacuolar proton-ATPase
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Sequence caution: Sequence=AAH10395.1; Type=Erroneous initiation; Sequence=AAQ13511.1; Type=Frameshift; Positions=155;Sequence=CAA76984.1; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for ATP6AP2:3LBS (3D)
3LC8 (3D)
Secondary accessions: Q5QTQ7 Q6T7F5 Q8NBP3 Q8NG15 Q96FV6 Q96LB5 Q9H2P8 Q9UG89Explore the universe of human proteins at neXtProt for ATP6AP2: NX_O75787
Post-translational modifications:
Phosphorylated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75787
ATP6AP2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005756.2
ENSEMBL proteins: ENSP00000367697 ENSP00000403969 ENSP00000411317 ENSP00000410105 ENSP00000438415 ENSP00000441536 ENSP00000440459 Reactome Protein details: O75787
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ATP6AP2 for ontologies About GeneDecksing
ATP6AP2 Antibody Products:
Assay Products for ATP6AP2: |
Protein
Domains /
Families
for ATP6AP2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATP6AP2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O75787ProtoNet protein and cluster: O75787 1 Blocks protein family: IPB012493 Renin receptor-like
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Function
for ATP6AP2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RENR_HUMAN, O75787Function: Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses byactivating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion toangiotensin I, it may also play a role in the renin-angiotensin system (RAS)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6AP2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6AP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ATP6AP2 (NM_005765) | |  | Sino Biological Human cDNA Clone for ATP6AP2 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP6AP2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6AP2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6AP2 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ATP6AP2 for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for ATP6AP2:
Animal Models:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Atp6ap2):
ATP6AP2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ATP6AP2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics | | | 2 | Wnt signaling network | | | 3 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 4 | Renin-angiotensin system | | | 5 | Insulin Processing | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3  BioSystems Pathways for ATP6AP2
3 
Reactome Pathways for ATP6AP2
2  PharmGKB Pathways for ATP6AP2
ATP6AP2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP6AP2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 17)
5/17 Interacting proteins for ATP6AP2 (O757873 ENSP000003676974) via UniProtKB, MINT, STRING, and/or I2D (see all 17)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
ATP6AP2 for ontologies About GeneDecksing
|
Drugs & Compounds
for ATP6AP2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ATP6AP2
Search CenterWatch for drugs/clinical trials and news about ATP6AP2 / RENR
|
Transcripts
for ATP6AP2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATP6AP2 gene: NM_005765.2 Unigene Cluster for ATP6AP2: ATPase, H+ transporting, lysosomal accessory protein 2 Hs.495960 [show with all ESTs]Unigene Representative Sequence: AK07538210 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000378438(uc004deu.1 uc004det.3 uc010nhc.3 uc011mkl.2 uc011mkm.2 uc011mkn.2)
ENST00000436783 ENST00000486558 ENST00000447485 ENST00000423649 ENST00000487051
ENST00000479120 ENST00000535539 ENST00000535777 ENST00000544975
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6AP2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6AP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ATP6AP2 (NM_005765) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP6AP2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6AP2 |
Additional cDNA sequence: AF109363.1 AF248966.1 AF291814.1 AK075382.1 AK293510.1 AK296614.1 AK297007.1 AK297760.1 AK314633.1 AK315948.1 AL049929.1 AY038990.1 AY429341.1 BC010395.1 BC084541.1 Y17975.1 19 DOTS entries: DT.448441 DT.101972338 DT.97825980 DT.100825404 DT.97769055 DT.91767534 DT.91767576 DT.95376036 DT.95376047 DT.95376038 DT.100037428 DT.121319307 DT.95376034 DT.121319288 DT.121319310 DT.91767535 DT.95156003 DT.95376035 DT.100825407 24/456 AceView cDNA sequences (see all 456): CA776340 AI419386 BU685017 BQ016104 BF726753 CK904571 BU607997 BU675541 AA788679 AI567371 CA388902 AA605267 BU193939 Y17975 AI205633 CK904572 BE897106 AA470629 AA417822 AA952967 BM464555 AI963141 BM974154 AA599849
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ATP6AP2 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ATP6AP2
|
Expression
for ATP6AP2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATP6AP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATATAAAAC
About this image
See ATP6AP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATP6AP2
SOURCE GeneReport for Unigene cluster: Hs.495960
UniProtKB/Swiss-Prot: RENR_HUMAN, O75787Tissue specificity: Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung andskeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidneyartery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed invascular structures and by syncytiotrophoblast cells in the mature fetal placenta
SABiosciences Expression via Pathway-Focused PCR Array including ATP6AP2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6AP2
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6AP2 |
Orthologs
for ATP6AP2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ATP6AP2 gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Atp6ap21 , 5 |
ATPase, H+ transporting, lysosomal accessory protein 2 less1, 5 |
89.78(n)1
94.27(a)1 |
|
X (7.42 cM)5
704951 NM_027439.41 NP_081715.11
125878015 |
chicken
(Gallus gallus) |
Aves |
ATP6AP21 |
ATPase, H+ transporting, lysosomal accessory protein 2 less |
72.66(n)
75.71(a) |
|
418573 NM_001030801.1 NP_001025972.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ATP6AP26 |
-- |
78(a) |
1 ↔ 1 |
3(133814686-133822437) |
African clawed frog
(Xenopus laevis) |
Amphibia |
atp6ap2-prov2 |
ATPase, H+ transporting, lysosomal accessory protein 2 less |
74.99(n) |
|
BC056060.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufj36c032 |
Danio rerio cDNA clone MGC73194 IMAGE4788954, complete cds less |
71.93(n) |
|
BC059542.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
VhaM8.91 |
CG8444-PA |
41.01(n)
29.34(a) |
|
41104 NM_141619.2 NP_649876.1 |
ENSEMBL Gene Tree for ATP6AP2 (if available)
TreeFam Gene Tree for ATP6AP2 (if available) |
Paralogs
for ATP6AP2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ATP6AP2 gene
ATP6AP2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ATP6AP2
PGOHUM00000245144
|
Genomic Variants
for ATP6AP2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATP6AP2 (40440146 - 40465889 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ATP6AP2
2 CNVs: 7785 103242
1 Indel: 47810
Human Gene Mutation Database (HGMD): ATP6AP2
Locus Specific Mutation Databases (LSDB): ATP6AP2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6AP2 |
|
Disorders
/ Diseases
for ATP6AP2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATP6AP2 for disorders About GeneDecksing
OMIM gene information: 300556
OMIM disorders: 300423
UniProtKB/Swiss-Prot: RENR_HUMAN, O75787
Defects in ATP6AP2 are a cause of mental retardation X-linked with epilepsy (MRXE) [MIM:300423]. MRXE is asyndromic mental retardation. Patients manifest mild to moderate mental retardation associated with epilepsy, delaysin motor milestones and speech acquisition in infancy
14  diseases for ATP6AP2: About MalaCardsmental retardation, x-linked x-linked mental retardation with epilepsy mental retardation epilepsy aortic valve stenosis
aortic aneurysm glomerulosclerosis epilepsy syndrome nephropathy
kidney disease aldosteronism atherosclerosis glioblastoma
hypertension retinitis
1 disease from the University of Copenhagen DISEASES database for ATP6AP2:Hypertension Human Genome Epidemiology (HuGE) Navigator: ATP6AP2 (1 document)
Export disorders for ATP6AP2 gene to outside databases
|
Publications
for ATP6AP2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATP6AP2 gene, integrated from 9 sources (see all 66):
(articles sorted by number of sources associating them with ATP6AP2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules. (PubMed id 9556572)1, 2, 3 Ludwig J....Schaegger H. (1998)
- A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor. (PubMed id 15746149)1, 2, 9 Ramser J....Nguyen G. (2005)
- Identification, genomic structure, and screening of the vacuolar proton-ATPase membrane sector-associated protein M8-9 gene within the COD1 critical region (Xp11.4). (PubMed id 11590366)1, 3, 9 Demirci F.Y....Gorin M.B. (2001)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. (PubMed id 12045255)1, 2 Nguyen G.... Sraer J.-D. (2002)
- Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
- Elevated blood pressure and heart rate in human renin receptor transgenic rats. (PubMed id 16401765)1, 9 Burckle C.A....Nguyen G. (2006)
- Soluble (pro)renin receptor and blood pressure during pregnancy: a prospective cohort study. (PubMed id 23045457)1 Watanabe N....Ichihara A. (2012)
- (Pro)renin receptor: another member of the system cont rolled by angiotensin II? (PubMed id 21997900)1 Pereira L.G....Boim M.A. (2012)
|
External Searches for ATP6AP2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ATP6AP2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ATP6AP2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ATP6AP2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ATP6AP2 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ATP6AP2 |
|
| | |
About This Section
| Patent Information for ATP6AP2 gene:
Search GeneIP for patents involving ATP6AP2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ATP6AP2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for ATP6AP2 | | OriGene shRNA RFP for ATP6AP2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP6AP2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP6AP2 | | | OriGene Protein Over-expression Lysate for ATP6AP2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATP6AP2 | | OriGene 3'-UTR Clone for ATP6AP2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6AP2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP6AP2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ATP6AP2 | | OriGene Custom Protein Services for ATP6AP2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATP6AP2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP6AP2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6AP2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP6AP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP6AP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP6AP2 |
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| | | | Search Tocris compounds for ATP6AP2 |
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 | | | ATP6AP2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP6AP2 |
|  |  |  | | | | ThermoFisher Antibodies for ATP6AP2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP6AP2 |
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