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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATP6AP1 Gene

protein-coding   GIFtS: 57
GCID: GC0XP153657

ATPase, H+ transporting, lysosomal accessory protein 1

(Previous names: ATPase, H+ transporting, lysosomal (vacuolar proton pump),...)
(Previous symbols: ATP6S1, ATP6IP1)
 Explore 12 diseases affiliated with
ATP6AP1 via our new
 Human Malady Compendium 
Biological research products
for ATP6AP1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
ATPase, H+ Transporting, Lysosomal Accessory Protein 11 2     Protein XAP-32 3
ATP6IP11 2 3 5     Vacuolar Proton Pump Subunit S12 3
ATP6S11 2 3 5     V-ATPase Ac45 Subunit2 3
VATPS11 2 3 5     V-ATPase S1 Accessory Protein2 3
XAP31 2 3     V-ATPase Subunit S12 3
16A1 2     ORF1
Ac451 2     ATPase, H+ Transporting, Lysosomal Interacting Protein 12
CF21 2     H-ATPase Subunit2
XAP-31 2     V-Type Proton ATPase Subunit S12
ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump), Subunit 11 2     

External Ids:    HGNC: 8681   Entrez Gene: 5372   Ensembl: ENSG000000715537   OMIM: 3001975   UniProtKB: Q159043   

Export aliases for ATP6AP1 gene to outside databases

Previous GC identifers: GC0XP151242 GC0XP152124 GC0XP153177 GC0XP153310 GC0XP142234


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ATP6AP1:
This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic
intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site)
and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular
processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene
is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: VAS1_HUMAN, Q15904
Function: Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By
similarity)

Gene Wiki entry for ATP6AP1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_167198.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATP6AP1 gene promoter:
         AP-1   ATF-2   Nkx2-5   c-Jun   YY1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATP6AP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ATP6AP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP6AP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

ATP6AP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP6AP1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP153657:  view genomic region     (about GC identifiers)

Start:
153,656,978 bp from pter      End:
153,664,862 bp from pter
Size:
7,885 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: VAS1_HUMAN, Q15904 (See protein sequence)
Recommended Name: V-type proton ATPase subunit S1 precursor  
Size: 470 amino acids; 52026 Da
Subunit: Composed of at least 10 subunits
Subcellular location: Vacuole membrane; Single-pass membrane protein (By similarity)
Sequence caution: Sequence=BAA03938.1; Type=Erroneous initiation;
Secondary accessions: A6ZKI4

Explore the universe of human proteins at neXtProt for ATP6AP1: NX_Q15904

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q15904

  • ATP6AP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001174.2  
    ENSEMBL proteins: 
     ENSP00000358777   ENSP00000398511   ENSP00000392375   ENSP00000408317   ENSP00000411209  
     ENSP00000396643   ENSP00000408470  

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    Uscn Proteins for ATP6AP1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005774vacuolar membrane IEA--
    GO:0016021integral to membrane IEA--
    GO:0016469proton-transporting two-sector ATPase complex TAS8733135
    GO:0033180proton-transporting V-type ATPase, V1 domain IEA--


    ATP6AP1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ATP6AP1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR024722 BIG/ATPase_V1_suS1
     IPR008388 ATPase_V1-cplx_s1su

    Graphical View of Domain Structure for InterPro Entry Q15904

    ProtoNet protein and cluster: Q15904

    1 Blocks protein family: IPB008388 Vacuolar ATP synthase subunit S1

    UniProtKB/Swiss-Prot: VAS1_HUMAN, Q15904
    Similarity: Belongs to the vacuolar ATPase subunit S1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: VAS1_HUMAN, Q15904
    Function: Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By
    similarity)

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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity TAS8733135
    GO:0005524ATP binding IEA--
    GO:0046933proton-transporting ATP synthase activity, rotational mechanism IEA--
    GO:0046961proton-transporting ATPase activity, rotational mechanism IEA--


    ATP6AP1 for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for ATP6AP1:
     Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A virus in  Decreased influenza A/WSN/33 r 
     Upregulation of Wnt/beta-caten 

    Animal Models:
         Mouse knock-out Atp6ap1tm1Gjmm for ATP6AP1
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Atp6ap1):
     mortality/aging 

    ATP6AP1 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Oxidative phosphorylation0.63
    Oxidative phosphorylation0.52
    2Insulin receptor recycling
    Vibrio cholerae infection0.41
    Epithelial cell signaling in Helicobacter pylori infection0.33
    3Rheumatoid arthritis
    Rheumatoid arthritis1.00
    4Tuberculosis
    Tuberculosis1.00
    5Lysosome
    Lysosome1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for ATP6AP1 
        Oxidative phosphorylation


    5/8         Kegg Pathways  (Kegg details for ATP6AP1) (see all 8):
        Oxidative phosphorylation
    Metabolic pathways
    Lysosome
    Phagosome
    Vibrio cholerae infection


    ATP6AP1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP6AP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/59 Interacting proteins for ATP6AP1 (Q159043 ENSP000003587774) via UniProtKB, MINT, STRING, and/or I2D (see all 59)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HBA1P699053, ENSP000003224214I2D: score=3 STRING: ENSP00000322421
    HBA2P699053, ENSP000002515954I2D: score=3 STRING: ENSP00000251595
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    ANGP039503I2D: score=4 
    SLC2A4P146723I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007568aging ----
    GO:0008219cell death ----
    GO:0015991ATP hydrolysis coupled proton transport IEA--
    GO:0015992proton transport TAS8733135


    ATP6AP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ATP6AP1 for compounds           About GeneDecksing

    EMD Millipore small molecules for ATP6AP1:
    Small Molecule - inhibitor
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    4 HMDB Compounds for ATP6AP1    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--
    WaterDihydrogen oxide (see all 2)7732-18-5--
    4 Novoseek chemical compound relationships for ATP6AP1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    bicarbonate 46.5 2 8933510 (1), 16736446 (1)
    potassium 23.1 2 17151195 (1)
    atp 15.8 1 9083109 (1)
    calcium 0 1 9083109 (1)

    Search CenterWatch for drugs/clinical trials and news about ATP6AP1 / VAS1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ATP6AP1 gene: 
    NM_001183.4  

    Unigene Clusters for ATP6AP1:

    ATPase, H+ transporting, lysosomal accessory protein 1
    Hs.6551  [show with all ESTs], Hs.633817  [show with all ESTs]
    Unigene Representative Sequences: NM_001183, BU565556
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369762(uc004flf.1) ENST00000422890 ENST00000449556 ENST00000439372
    ENST00000446552 ENST00000455205(uc004flg.1) ENST00000429585 ENST00000491569(uc004flh.1)
    ENST00000484908

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    Additional cDNA sequence: 

    X74605.1 X87195.1 

    24/58 DOTS entries (see all 58):

    DT.91926786  DT.419124  DT.95288900  DT.121294573  DT.100863143  DT.100863129  DT.121294551  DT.100863118 
    DT.100863116  DT.100863120  DT.121293887  DT.100863139  DT.121294589  DT.100763485  DT.121294456  DT.121293650 
    DT.121293985  DT.121294692  DT.100863137  DT.97788318  DT.100863133  DT.121294453  DT.97860391  DT.100863134 

    24/335 AceView cDNA sequences (see all 335):

    N44767 BX461330 CA454760 BQ712413 BM452886 BU556514 CB131445 CA395009 
    AA335323 AA346890 CA392104 BM451707 BE314742 BI908430 BE273655 BP375215 
    BQ213125 BM470809 BP373376 BG821897 BG747237 CF132654 BI667688 BX375559 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ATP6AP1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c
    SP1:                                -     -                                                         
    SP2:                                -     -                                                         
    SP3:                                      -                                                         
    SP4:                                -     -                 -     -     -     -                     
    SP5:                                                                                                


    ECgene alternative splicing isoforms for ATP6AP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATP6AP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGGTGCTTGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ATP6AP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATP6AP1

    SOURCE GeneReport for Unigene clusters: Hs.6551 Hs.633817

    UniProtKB/Swiss-Prot: VAS1_HUMAN, Q15904
    Tissue specificity: Ubiquitous

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ATP6AP1 gene from 4/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves ATP6AP11 ATPase, H+ transporting, lysosomal accessory protein more 49.38(n)
    41.67(a)
      427854  NM_001252611.1  NP_001239540.1 
    lizard
    (Anolis carolinensis)
    Reptilia ATP6AP16
    --
    69(a)
    1 ↔ 1
    2(89835996-89842821)
    African clawed frog
    (Xenopus laevis)
    Amphibia X13112 glycoprotein 76.58(n)    X82421.1 
    zebrafish
    (Danio rerio)
    Actinopterygii atp6ap12 ATPase, H+ transporting, lysosomal accessory protein more 71.79(n)   195824  AY099513.1 


    ENSEMBL Gene Tree for ATP6AP1 (if available)
    TreeFam Gene Tree for ATP6AP1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ATP6AP1 gene
    ATP6AP1L2  
    3 SIMAP similar genes for ATP6AP1 using alignment to 6 protein entries:     VAS1_HUMAN (see all proteins):
    DKFZp434B0535    FLJ00383    ATP6AP1L

    ATP6AP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/122 NCBI SNPs in ATP6AP1 are shown (see all 122    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1875104891,2
    --153654996(+) GATCTC/TGGCTC 1 -- us2k10--------
    rs1926064151,2
    --153655397(+) TCAACC/TTTTGG 1 -- us2k10--------
    rs1493689571,2
    --153655424(+) TATCAC/TGACCT 1 -- us2k10--------
    rs1447875781,2
    --153655611(+) CAGCAA/GCAGAG 1 -- us2k10--------
    rs1833269541,2
    --153655800(+) TGGCCA/TCTTGG 1 -- us2k10--------
    rs1879385001,2
    --153655956(+) AGTCCC/TAGTCT 1 -- us2k10--------
    rs1922202511,2
    --153656129(+) ACTGGA/GACTAC 1 -- us2k10--------
    rs1849043671,2
    --153656393(+) GCCCAA/TTGTAA 1 -- us2k10--------
    rs1894017741,2
    --153656844(+) GAGCGG/TGAGCG 1 -- us2k10--------
    rs1916341281,2
    --153656853(+) CGCCTA/GGAGAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ATP6AP1 (153656978 - 153664862 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ATP6AP1: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ATP6AP1 for disorders           About GeneDecksing

    OMIM gene information: 300197    OMIM disorders: --

    12 diseases for ATP6AP1:    About MalaCards
    tinea nigra    renal tubular acidosis    bullous pemphigoid    rett syndrome
    cystic fibrosis    sjogren's syndrome    rheumatoid arthritis    measles
    cholera    arthritis    fibrosis    tuberculosis

    1 disease from the University of Copenhagen DISEASES database for ATP6AP1:
    Cystic fibrosis

    2 Novoseek disease relationships for ATP6AP1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hypokalemia 56.5 3 1836966 (1), 10592934 (1)
    metabolic acidosis 42 2 1836966 (1)

    Human Genome Epidemiology (HuGE) Navigator: ATP6AP1 (3 documents)

    Export disorders for ATP6AP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATP6AP1 gene, integrated from 9 sources (see all 55):
    (articles sorted by number of sources associating them with ATP6AP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci. (PubMed id 8733135)1, 2, 3 Chen E.Y....D'Urso M. (1996)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Isolation of expressed sequences encoded by the human Xq terminal portion using microclone probes generated by laser microdissection. (PubMed id 8034313)1, 2 Yokoi H.... Ikeda J. (1994)
    5. Construction of a transcription map of a 300 kb region around the human G6PD locus by direct cDNA selection. (PubMed id 8281148)1, 3 Sedlacek Z.... Poustka A. (1993)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. Proteomic identification of common SCF ubiquitin ligas e FBXO6-interacting glycoproteins in three kinds of cells. (PubMed id 22268729)1 Liu B....Wang L.S. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 537 HGNC: 868 AceView: ATP6AP1 Ensembl:ENSG00000071553 euGenes: HUgn537
    ECgene: ATP6AP1 Kegg: 537 H-InvDB: ATP6AP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATP6AP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ATP6AP1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ATP6AP1 gene:
    Search GeneIP for patents involving ATP6AP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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