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Aliases for ATP5SL Gene

Aliases for ATP5SL Gene

  • ATP5S Like 2 3
  • ATP5S-Like 3 5

External Ids for ATP5SL Gene

Previous GeneCards Identifiers for ATP5SL Gene

  • GC19M046630
  • GC19M041937
  • GC19M038368

Summaries for ATP5SL Gene

GeneCards Summary for ATP5SL Gene

ATP5SL (ATP5S Like) is a Protein Coding gene. An important paralog of this gene is ATP5S.

Gene Wiki entry for ATP5SL Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ATP5SL Gene

Genomics for ATP5SL Gene

Regulatory Elements for ATP5SL Gene

Genomic Location for ATP5SL Gene

Chromosome:
19
Start:
41,431,318 bp from pter
End:
41,447,827 bp from pter
Size:
16,510 bases
Orientation:
Minus strand

Genomic View for ATP5SL Gene

Genes around ATP5SL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ATP5SL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ATP5SL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ATP5SL Gene

Proteins for ATP5SL Gene

  • Protein details for ATP5SL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NW81-AT5SL_HUMAN
    Recommended name:
    ATP synthase subunit s-like protein
    Protein Accession:
    Q9NW81
    Secondary Accessions:
    • B4DDC0
    • B4DMZ4
    • B4DP55
    • B4DXE8
    • F5H4W7
    • K7EMF6
    • Q96D43

    Protein attributes for ATP5SL Gene

    Size:
    257 amino acids
    Molecular mass:
    29267 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ATP5SL Gene

neXtProt entry for ATP5SL Gene

Proteomics data for ATP5SL Gene at MOPED

Post-translational modifications for ATP5SL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ATP5SL Gene

Domains & Families for ATP5SL Gene

Protein Domains for ATP5SL Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ATP5SL Gene

Graphical View of Domain Structure for InterPro Entry

Q9NW81

UniProtKB/Swiss-Prot:

AT5SL_HUMAN :
  • Belongs to the ATP synthase subunit s family.
Family:
  • Belongs to the ATP synthase subunit s family.
genes like me logo Genes that share domains with ATP5SL: view

No data available for Gene Families for ATP5SL Gene

Function for ATP5SL Gene

Phenotypes for ATP5SL Gene

genes like me logo Genes that share phenotypes with ATP5SL: view

Animal Model Products

CRISPR Products

miRNA for ATP5SL Gene

miRTarBase miRNAs that target ATP5SL

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ATP5SL Gene

Localization for ATP5SL Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ATP5SL Gene COMPARTMENTS Subcellular localization image for ATP5SL gene
Compartment Confidence
mitochondrion 3
nucleus 2
cytosol 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ATP5SL Gene

Pathways & Interactions for ATP5SL Gene

SuperPathways for ATP5SL Gene

No Data Available

Interacting Proteins for ATP5SL Gene

Gene Ontology (GO) - Biological Process for ATP5SL Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ATP5SL Gene

Drugs & Compounds for ATP5SL Gene

No Compound Related Data Available

Transcripts for ATP5SL Gene

Unigene Clusters for ATP5SL Gene

ATP5S-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ATP5SL Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f · 9g · 9h ^ 10a ·
SP1: - - -
SP2: - - - - - - -
SP3: - - - - - -
SP4: - - -
SP5: -
SP6: - - - - - -
SP7: - - -
SP8: -
SP9: - - - - - - - -
SP10: - - - -
SP11: - - - - - - - - - -
SP12: - - - -
SP13: - - -
SP14: - - - - - - -
SP15: - - - - -
SP16: - - - - - -
SP17: - - - - - - - -

ExUns: 10b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:

Relevant External Links for ATP5SL Gene

GeneLoc Exon Structure for
ATP5SL
ECgene alternative splicing isoforms for
ATP5SL

Expression for ATP5SL Gene

mRNA expression in normal human tissues for ATP5SL Gene

Protein differential expression in normal tissues from HIPED for ATP5SL Gene

This gene is overexpressed in Bone (21.9), Liver (21.1), and Breast (20.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ATP5SL Gene



SOURCE GeneReport for Unigene cluster for ATP5SL Gene Hs.351099

genes like me logo Genes that share expression patterns with ATP5SL: view

Protein tissue co-expression partners for ATP5SL Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ATP5SL Gene

Orthologs for ATP5SL Gene

This gene was present in the common ancestor of animals.

Orthologs for ATP5SL Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ATP5SL 35
  • 81.32 (n)
  • 74.71 (a)
ATP5SL 36
  • 71 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ATP5SL 35
  • 78.86 (n)
  • 70.43 (a)
ATP5SL 36
  • 68 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Atp5sl 35
  • 76.13 (n)
  • 67.2 (a)
Atp5sl 16
Atp5sl 36
  • 65 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ATP5SL 35
  • 98.18 (n)
  • 97.67 (a)
ATP5SL 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Atp5sl 35
  • 75.59 (n)
  • 67.32 (a)
lizard
(Anolis carolinensis)
Reptilia ATP5SL 36
  • 34 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia atp5sl 35
  • 55.82 (n)
  • 47.85 (a)
zebrafish
(Danio rerio)
Actinopterygii si:ch1073-228b5.2 35
  • 50.41 (n)
  • 41.95 (a)
ATP5SL 36
  • 33 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG4042 36
  • 20 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y53G8AR.8 36
  • 15 (a)
OneToOne
Species with no ortholog for ATP5SL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ATP5SL Gene

ENSEMBL:
Gene Tree for ATP5SL (if available)
TreeFam:
Gene Tree for ATP5SL (if available)

Paralogs for ATP5SL Gene

Paralogs for ATP5SL Gene

genes like me logo Genes that share paralogs with ATP5SL: view

Variants for ATP5SL Gene

Sequence variations from dbSNP and Humsavar for ATP5SL Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs2231938 - 41,438,408(-) CCCTG(C/T)GCCTG nc-transcript-variant, reference, missense, utr-variant-5-prime
rs2231939 - 41,438,365(-) CATCC(A/G)TCGCC nc-transcript-variant, reference, missense
rs2231940 - 41,438,332(-) GGGCA(A/G)TCAGA nc-transcript-variant, reference, missense
rs2231943 - 41,432,317(-) ATTGC(A/G)AGGTT nc-transcript-variant, reference, synonymous-codon, missense
rs1043413 - 41,433,392(-) CTGCT(C/G)CCACG intron-variant, nc-transcript-variant, reference, missense

Variation tolerance for ATP5SL Gene

Residual Variation Intolerance Score: 94.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.32; 53.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ATP5SL Gene

HapMap Linkage Disequilibrium report
ATP5SL
Human Gene Mutation Database (HGMD)
ATP5SL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ATP5SL Gene

Disorders for ATP5SL Gene

Relevant External Links for ATP5SL

Genetic Association Database (GAD)
ATP5SL
Human Genome Epidemiology (HuGE) Navigator
ATP5SL
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ATP5SL

No disorders were found for ATP5SL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ATP5SL Gene

Publications for ATP5SL Gene

  1. Hundreds of variants clustered in genomic loci and biological pathways affect human height. (PMID: 20881960) Lango Allen H. … Hirschhorn J.N. (Nature 2010) 3 48 67
  2. A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. (PMID: 23065704) Amin Al Olama A. … Eeles R.A. (Hum. Mol. Genet. 2013) 3
  3. DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population. (PMID: 21682944) Alkelai A. … Lerer B. (Int. J. Neuropsychopharmacol. 2012) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  5. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3

Products for ATP5SL Gene

Sources for ATP5SL Gene

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