Aliases for ATP5G3 Gene
- ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit C3 (Subunit 9) 2 3 5
- ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subunit C3 (Subunit 9) 2 3
- ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit C3 (Subunit 9) 2 3
- ATP Synthase Proton-Transporting Mitochondrial F(0) Complex Subunit C3 3 4
- ATP Synthase Proteolipid P3 3 4
- ATPase Subunit C 3 4
- ATPase Protein 9 3 4
External Ids for ATP5G3 Gene
Previous GeneCards Identifiers for ATP5G3 Gene
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]
GeneCards Summary for ATP5G3 Gene
ATP5G3 (ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit C3 (Subunit 9)) is a Protein Coding gene. Among its related pathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include transporter activity and hydrogen ion transmembrane transporter activity. An important paralog of this gene is ATP5G1.
UniProtKB/Swiss-Prot for ATP5G3 Gene
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.