ATP5E Gene
protein-coding GIFtS: 52
GCID: GC20M057600
|
|
ATP synthase, H+ transporting, mitochondrial F1 complex,...
| |
Aliases
for ATP5E gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, Epsilon Subunit1 2 | | H(+)-Transporting Two-Sector ATPase2 | | ATPE2 | | Mitochondrial ATP Synthase Epsilon Chain2 | | F(0)F(1)-ATPase2 | | Mitochondrial ATPase2 | | MC5DN32 | | ATPase Subunit Epsilon3 | | ATP Synthase Subunit Epsilon, Mitochondrial2 | | |
Export aliases for ATP5E gene to outside databasesPrevious GC identifers: GC20M057332 GC20M058239 GC20M058289 GC20M057037 GC20M054390 |
Summaries
for ATP5E gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ATP5E:
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis,utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATPsynthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanningcomponent, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and asingle representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodesthe epsilon subunit of the catalytic core. Two pseudogenes of this gene are located on chromosomes 4 and 13.Read-through transcripts that include exons from this gene are expressed from the upstream gene SLMO2.(provided byRefSeq, Mar 2011)
UniProtKB/Swiss-Prot: ATP5E_HUMAN, P56381Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in thepresence of a proton gradient across the membrane which is generated by electron transport complexes of therespiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalyticcore, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalksubunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of thecomplex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads tohydrolysis of ATP in three separate catalytic sites on the beta subunits (By similarity)
Gene Wiki entry for ATP5E
|
Genomic Views
for ATP5E gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ATP5E gene promoter:
SRF C/EBPbeta p53 SRF (504 AA)
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATP5E
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP5E |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q13.32 Ensembl cytogenetic band: 20q13.32 HGNC cytogenetic band: 20q13.3ATP5E Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M057600: view genomic region
(about GC identifiers)
Start:
|
57,600,522 bp from pter |
End:
|
57,607,437 bp from pter |
Size:
|
6,916 bases |
Orientation:
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minus strand |
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Proteins
for ATP5E gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ATP5E_HUMAN, P56381 (See
protein sequence)Recommended Name: ATP synthase subunit epsilon, mitochondrial Size: 51 amino acids; 5780 Da
Subunit: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1)has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) seems to have nine subunits: a, b, c, d,e, f, g, F6 and 8 (or A6L). Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I,ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68 (By similarity)
Subcellular location: Mitochondrion. Mitochondrion inner membrane
Secondary accessions: B2RDD0 E1P5H6 Q53XU6Explore the universe of human proteins at neXtProt for ATP5E: NX_P56381
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P56381
ATP5E Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_008817.1
ENSEMBL proteins: ENSP00000243997 ENSP00000379023 ENSP00000379019 Reactome Protein details: P56381
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) |
IEA | -- | | GO:0005739 | mitochondrion |
-- | -- | | GO:0005753 | mitochondrial proton-transporting ATP synthase complex |
IDA | 12110673 | | GO:0005759 | mitochondrial matrix |
TAS | -- |
ATP5E for ontologies About GeneDecksing
ATP5E Antibody Products:
Assay Products for ATP5E: |
Protein
Domains /
Families
for ATP5E gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATP5E for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P56381ProtoNet protein and cluster: P56381 1 Blocks protein family: IPB006721 Mitochondrial ATP synthase epsilon chain
UniProtKB/Swiss-Prot: ATP5E_HUMAN, P56381Similarity: Belongs to the eukaryotic ATPase epsilon family |
Function
for ATP5E gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ATP5E_HUMAN, P56381Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in thepresence of a proton gradient across the membrane which is generated by electron transport complexes of therespiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalyticcore, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalksubunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of thecomplex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads tohydrolysis of ATP in three separate catalytic sites on the beta subunits (By similarity) Genatlas biochemistry entry for ATP5E:ATP synthase H+ transporting,mitochondrial matrix (F1 segment) subunit 5,epsilon subunit,complex V of oxidativephosphorylation (OXPHOS)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5E (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5E (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ATP5E (NM_006886) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP5E | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP5E |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016887 | contributes to ATPase activity |
IDA | 12110673 | | GO:0022857 | transmembrane transporter activity |
IC | 12110673 | | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism |
IEA | -- | | GO:0046961 | proton-transporting ATPase activity, rotational mechanism |
IEA | -- |
ATP5E for ontologies About GeneDecksing
|
Pathways & Interactions
for ATP5E gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 2 | Metabolism | | | 3 | Doxorubicin Pathway (Cardiomyocyte Cell), Pharmacodynamics | | | 4 | Formation of ATP by chemiosmotic coupling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for ATP5E
4 
Reactome Pathways for ATP5E
1  PharmGKB Pathway for ATP5E
5 
Kegg Pathways (Kegg details for ATP5E):
ATP5E for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP5E
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/55 Interacting proteins for ATP5E (ENSP000002439974) via UniProtKB, MINT, STRING, and/or I2D (see all 55)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006200 | ATP catabolic process |
IDA | 12110673 | | GO:0022904 | respiratory electron transport chain |
TAS | -- | | GO:0042776 | mitochondrial ATP synthesis coupled proton transport |
TAS | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- |
ATP5E for ontologies About GeneDecksing
|
Drugs & Compounds
for ATP5E gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ATP5E for compounds About GeneDecksing
 Browse Tocris compounds for ATP5E
4 HMDB Compounds for ATP5E About this table
10 Novoseek chemical compound relationships for ATP5E gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| oligomycin |
81.8 |
10 |
19000650 (2), 2143151 (1), 2161214 (1), 9916153 (1) (see all 8) |
| atp |
63.3 |
15 |
2143151 (2), 9030519 (1), 8276114 (1), 7721821 (1) (see all 11) |
| rotenone |
61.9 |
2 |
8276114 (1), 10549166 (1) |
| fccp |
59.7 |
1 |
9030519 (1) |
| cdp choline |
53.9 |
2 |
8709678 (1), 17171187 (1) |
| 2,4-dinitrophenol |
41.4 |
1 |
9030519 (1) |
| lactate |
21.9 |
5 |
1832835 (1), 7787252 (1), 19639598 (1), 2375763 (1) (see all 5) |
| adenine |
19.2 |
1 |
8726359 (1) |
| leucine |
18.8 |
3 |
8190310 (1), 8476414 (1), 7957931 (1) |
| oxygen |
13.4 |
1 |
16268759 (1) |
Search CenterWatch for drugs/clinical trials and news about ATP5E
|
Transcripts
for ATP5E gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATP5E gene: NM_006886.3 Unigene Cluster for ATP5E: ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit Hs.177530 [show with all ESTs]Unigene Representative Sequence: BG7417743 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000243997(uc002yal.3) ENST00000395663 ENST00000395659
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5E (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5E (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ATP5E (NM_006886) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP5E | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP5E |
Additional cDNA sequence: AF052955.1 AF077045.1 AK026556.1 AK315493.1 BC001690.1 BC003671.1 BC070167.1 BC105811.1 BT007293.1 24/38 DOTS entries (see all 38): DT.449876 DT.100686215 DT.101987288 DT.99986093 DT.100693858 DT.100686219 DT.100686212 DT.442802 DT.120780343 DT.75128728 DT.120805402 DT.120805398 DT.120780342 DT.95324298 DT.100686217 DT.120805471 DT.120805485 DT.120805418 DT.95207918 DT.120805422 DT.120805449 DT.120805456 DT.120805467 DT.92448286 24/926 AceView cDNA sequences (see all 926): AA977143 BM759104 F27119 AA315955 BX341636 AA700688 CA441920 BI333288 AA442417 AI283323 CA429619 BQ058231 CB119177 BM742608 AA600707 AI358520 BQ957008 AV726003 AA366883 Z39601 AI223418 AA035773 BU786745 NM_006886
GeneLoc Exon Structure
|
Expression
for ATP5E gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATP5E expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTATGGCAGA
About this image
See ATP5E Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATP5E
SOURCE GeneReport for Unigene cluster: Hs.177530
UniProtKB/Swiss-Prot: ATP5E_HUMAN, P56381Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for ATP5E
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP5E
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ATP5E | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP5E | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP5E |
Orthologs
for ATP5E gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ATP5E gene from 4/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Atp5e5 |
ATP synthase, H+ transporting, mitochondrial F1 complex, more |
-- |
|
2 (97.95 cM) 174461072 |
chicken
(Gallus gallus) |
Aves |
-- |
Uncharacterized protein |
71(a) |
1 → many |
20(10838171-10838409) |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
88(a) |
1 → many |
GL343770.1(169479-172052) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:ch211-122i22.56 |
si:ch211-122i22.5 |
65(a) |
1 → many |
6(49845154-49853806) |
ENSEMBL Gene Tree for ATP5E (if available)
TreeFam Gene Tree for ATP5E (if available) |
Paralogs
for ATP5E gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ATP5E gene
- ATP5EP22
1 SIMAP similar gene for ATP5E using alignment to 1 protein entry: ATP5E_HUMAN:ATP5EP2
ATP5E for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ATP5E
PGOHUM00000246018
|
Genomic Variants
for ATP5E gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATP5E (57600522 - 57607437 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ATP5E: --
Human Gene Mutation Database (HGMD): ATP5E
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP5E |
|
Disorders
/ Diseases
for ATP5E gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATP5E for disorders About GeneDecksing
OMIM gene information: 606153
OMIM disorders: --
UniProtKB/Swiss-Prot: ATP5E_HUMAN, P56381
Defects in ATP5E are the cause of mitochondrial complex V deficiency nuclear type 3 (MC5DN3) [MIM:614053].MC5DN3 is a mitochondrial disorder with heterogeneous clinical manifestations including dysmorphic features,psychomotor retardation, hypotonia, growth retardation, cardiomyopathy, enlarged liver, hypoplastic kidneys andelevated lactate levels in urine, plasma and cerebrospinal fluid
20  diseases for ATP5E: About MalaCardsmitochondrial complex v deficiency ceroid lipofuscinosis neuronal ceroid-lipofuscinosis complex v
lactic acidosis renal oncocytoma intrahepatic cholangiocarcinoma epididymitis
huntington's disease hypotonia cholangiocarcinoma parkinson's disease
ischemia colon cancer myopathy cardiomyopathy
neuronitis carcinoma adult neuronal ceroid lipofuscinosis alcoholism
5 Novoseek disease relationships for ATP5E gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| leigh syndrome |
53.7 |
1 |
8190310 (1) |
| mitochondrial diseases |
47.5 |
1 |
16581217 (1) |
| cerebral edema |
34.5 |
2 |
8709678 (1), 17171187 (1) |
| ischemia |
4.45 |
1 |
10536688 (1) |
| cancer |
0 |
1 |
17624334 (1) |
Human Genome Epidemiology (HuGE) Navigator: ATP5E (1 document)
Export disorders for ATP5E gene to outside databases
|
Publications
for ATP5E gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATP5E gene, integrated from 9 sources (see all 89):
(articles sorted by number of sources associating them with ATP5E) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning, characterization and mapping of the human ATP5E gene, identification of pseudogene ATP5EP1, and definition of the ATP5E motif. (PubMed id 10727396)1, 2, 3 Tu Q....Zhao S. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- Knockdown of F1 epsilon subunit decreases mitochondri al content of ATP synthase and leads to accumulation of subunit c. (PubMed id 20026007)1 HavlA-ckovA! V....Houstek J. (2010)
- Mitochondrial ATP synthase deficiency due to a mutation in the ATP5E gene for the F1 epsilon subunit. (PubMed id 20566710)2 Mayr J.A.... Houstek J. (2010)
- Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
- Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells. (PubMed id 19016746)1 Kim D.W....Park J.G. (2008)
|
External Searches for ATP5E gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ATP5E gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ATP5E gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ATP5E gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for ATP5E | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for ATP5E gene:
Search GeneIP for patents involving ATP5E
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ATP5E gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ATP5E | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP5E | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP5E | | | OriGene Protein Over-expression Lysate for ATP5E | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATP5E | | OriGene 3'-UTR Clone for ATP5E | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5E | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5E | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ATP5E | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ATP5E | | OriGene Custom Protein Services for ATP5E | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATP5E | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP5E | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP5E | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP5E | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP5E | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP5E |
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| | | | Search Tocris compounds for ATP5E |
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 | | | | |  |  |  | | | | ThermoFisher Antibodies for ATP5E |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP5E |
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