ATP5C1 Gene
protein-coding GIFtS: 60
GCID: GC10P007830
|
|
ATP synthase, H+ transporting, mitochondrial F1 complex,...
(Previous symbols: ATP5CL1, ATP5C)
| |
Aliases
for ATP5C1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, Gamma Polypeptide11 2 | | ATP Synthase Gamma Chain, Mitochondrial2 | | ATP5C1 2 3 5 | | ATP Synthase Subunit Gamma, Mitochondrial2 | | ATP5CL11 2 3 5 | | Mitochondrial ATP Synthase, Gamma Subunit 12 | | F-ATPase Gamma Subunit2 3 | | |
Export aliases for ATP5C1 gene to outside databasesPrevious GC identifers: GC10P007774 GC10P007980 GC10P007834 GC10P007870 |
Summaries
for ATP5C1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ATP5C1:
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis,utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATPsynthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanningcomponent, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and asingle representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodesthe gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms havebeen identified. This gene also has a pseudogene on chromosome 14. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ATPG_HUMAN, P36542Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in thepresence of a proton gradient across the membrane which is generated by electron transport complexes of therespiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalyticcore, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalksubunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complexrotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of thecentral stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalyticsites on the beta subunits
Gene Wiki entry for ATP5C1
|
Genomic Views
for ATP5C1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008705.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ATP5C1 gene promoter:
TBP FAC1 Elk-1 Pbx1a HFH-1 ATF-2 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATP5C1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP5C1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p15.1 Ensembl cytogenetic band: 10p14 HGNC cytogenetic band: 10p14ATP5C1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P007830: view genomic region
(about GC identifiers)
Start:
|
7,830,092 bp from pter |
End:
|
7,849,778 bp from pter |
Size:
|
19,687 bases |
Orientation:
|
plus strand |
|
Proteins
for ATP5C1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ATPG_HUMAN, P36542 (See
protein sequence)Recommended Name: ATP synthase subunit gamma, mitochondrial precursor Size: 298 amino acids; 32996 Da
Subunit: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1)has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8,ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68 (By similarity)
Subcellular location: Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein (By similarity)
Secondary accessions: A8KA31 Q5VYP3 Q6I9V2 Q96AS8Alternative splicing: 2 isoforms: P36542-1 P36542-2 Explore the universe of human proteins at neXtProt for ATP5C1: NX_P36542
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P36542
ATP5C1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001001973.1 NP_005165.1
ENSEMBL proteins: ENSP00000349142 ENSP00000338568 ENSP00000437565 Reactome Protein details: P36542
Human Recombinant Protein Products for ATP5C1:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
ATP5C1 for ontologies About GeneDecksing
ATP5C1 Antibody Products:
Assay Products for ATP5C1: |
Protein
Domains /
Families
for ATP5C1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATP5C1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P36542ProtoNet protein and cluster: P36542 1 Blocks protein family: IPB000131 H+-transporting two-sector ATPase
UniProtKB/Swiss-Prot: ATPG_HUMAN, P36542Similarity: Belongs to the ATPase gamma chain family |
Function
for ATP5C1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ATPG_HUMAN, P36542Function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in thepresence of a proton gradient across the membrane which is generated by electron transport complexes of therespiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalyticcore, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalksubunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complexrotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of thecentral stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalyticsites on the beta subunits Genatlas biochemistry entry for ATP5C1:ATP synthase H+ transporting,mitochondrial matrix (F1 segment),gamma subunit isoform 1,mainly expressed inheart,located in the mitochondrial matrix,complex V of oxidative phosphorylation (OXPHOS) with an alternative isoformin the liver differing by a deletion of an Asp(233)
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016887 | contributes to ATPase activity |
NAS | 8227057 | | GO:0022857 | transmembrane transporter activity |
IC | 12110673 | | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism |
IEA | -- | | GO:0046961 | proton-transporting ATPase activity, rotational mechanism |
IEA | -- |
ATP5C1 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5C1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5C1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ATP5C1 (NM_005174) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP5C1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP5C1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP5C1 |
|
Pathways & Interactions
for ATP5C1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 2 | Metabolism | | | 3 | Doxorubicin Pathway (Cardiomyocyte Cell), Pharmacodynamics | | | 4 | Formation of ATP by chemiosmotic coupling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for ATP5C1
4 
Reactome Pathways for ATP5C1
1  PharmGKB Pathway for ATP5C1
5 
Kegg Pathways (Kegg details for ATP5C1):
ATP5C1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP5C1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/593 Interacting proteins for ATP5C1 (P365422, 3 ENSP000003491424) via UniProtKB, MINT, STRING, and/or I2D (see all 593)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
ATP5C1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ATP5C1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ATP5C1
4 HMDB Compounds for ATP5C1 About this table
5 DrugBank Compounds for ATP5C1 About this table
Search CenterWatch for drugs/clinical trials and news about ATP5C1 / ATPG
|
Transcripts
for ATP5C1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATP5C1 gene (2 alternative transcripts): NM_001001973.1 NM_005174.2 Unigene Cluster for ATP5C1: ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 Hs.271135 [show with all ESTs]Unigene Representative Sequence: BF13162711 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000356708(uc009xiq.1 uc010qbc.1 uc001iju.3 uc001ijv.3)
ENST00000493053 ENST00000462760 ENST00000460362 ENST00000335698 ENST00000465936
ENST00000460820 ENST00000472202(uc010qbb.2) ENST00000473809 ENST00000480528
ENST00000541227
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5C1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5C1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ATP5C1 (NM_005174) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATP5C1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP5C1 |
Additional cDNA sequence: AK292896.1 AK294061.1 AK296803.1 BC000470.2 BC000931.3 BC010380.1 BC013394.2 BC013865.1 BC016812.1 BC020824.1 BC026049.1 CR457403.1 D16562.1 D16563.1 24/41 DOTS entries (see all 41): DT.454044 DT.91773081 DT.91773071 DT.95131607 DT.92376161 DT.91861811 DT.100840908 DT.121229932 DT.95181724 DT.91773080 DT.100886416 DT.91989112 DT.121229902 DT.100886424 DT.430382 DT.95181788 DT.100886401 DT.100886407 DT.100886383 DT.100886423 DT.121229878 DT.91910082 DT.100039108 DT.100763408 24/1014 AceView cDNA sequences (see all 1014): CA432708 BM907194 CA842799 BM312031 CA943209 AA298154 BF980814 BQ448448 BQ962663 BM848726 CN484048 CB160195 CA848743 BM841966 BU622511 CB132718 BM667127 BF106424 BC000931 CR611688 D16563 BQ926438 CR595574 BI676499
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for ATP5C1 (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | | | |
| SP3: | | | | | | | | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ATP5C1
|
Expression
for ATP5C1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATP5C1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACAATGCCA
About this image
See ATP5C1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATP5C1
SOURCE GeneReport for Unigene cluster: Hs.271135
UniProtKB/Swiss-Prot: ATPG_HUMAN, P36542Tissue specificity: Isoform Heart is expressed specifically in the heart and skeletal muscle, which require rapidenergy supply. Isoform Liver is expressed in the brain, liver and kidney. Isoform Heart and Isoform Liver areexpressed in the skin, intestine, stomach and aorta
SABiosciences Expression via Pathway-Focused PCR Arrays including ATP5C1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP5C1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP5C1 |
Orthologs
for ATP5C1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ATP5C1 gene from 11/39 species (see all 39) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Atp5c11 , 5 |
ATP synthase, H+ transporting, mitochondrial F1 complex, more1, 5 |
87.47(n)1
91.28(a)1 |
|
2 (6.86 cM)5
119491 NM_020615.41 NP_065640.21
100560165 |
chicken
(Gallus gallus) |
Aves |
ATP5C11 |
ATP synthase, H+ transporting, mitochondrial F1 complex, more |
78.34(n)
82.99(a) |
|
419108 XM_417296.3 XP_417296.2 |
lizard
(Anolis carolinensis) |
Reptilia |
ATP5C16 |
-- |
83(a) |
1 ↔ 1 |
5(185996-191076) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BC044680.12 |
-- |
78.13(n) |
|
BC044680.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufk34c052 |
wufk34c05 |
77.78(n) |
|
336957 BC060917.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
ATPsyn-&ggr;3
ATPsyn-gamma1 |
hydrogen transport hydrogen-transporting
two-sector more3
ATP synthase-gamma chain1 |
58(a)3
57.51(n)1
60.07(a)1 |
|
99B103
435071 NM_079826.31 NP_524550.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y69A2AR.18a3
CELE_Y69A2AR.181 |
Protein Y69A2AR.181 |
57(a)
(best of 2)3
58.67(n)1
58.91(a)1 |
|
IV(2495753-2497421)3
1770381 NM_067813.51 NP_500214.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
ATP3(YBR039W)4
ATP31 |
Gamma subunit of the F1 sector of mitochondrial F1F more4
Atp3p1 |
52.7(n)1
41.18(a)1 |
|
2(315575-316510)4
8523271, 4 NP_009595.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ATP31 |
ATP synthase subunit gamma |
50.92(n)
39.11(a) |
|
817866 NM_128864.3 NP_180863.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.107032 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
76.43(n) |
|
NM_195647.1 |
ENSEMBL Gene Tree for ATP5C1 (if available)
TreeFam Gene Tree for ATP5C1 (if available) |
Paralogs
for ATP5C1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ATP5C1 gene
ATP5C1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ATP5C1
PGOHUM00000247803
|
Genomic Variants
for ATP5C1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATP5C1 (7830092 - 7849778 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ATP5C1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP5C1 |
|
Disorders
/ Diseases
for ATP5C1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATP5C1 for disorders About GeneDecksing
OMIM gene information: 108729
OMIM disorders: --
9  diseases for ATP5C1: About MalaCardscomplex v huntington's disease parkinson's disease alzheimer's disease
pneumonia tuberculosis malaria prostatitis
mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: ATP5C1 (4 documents)
Export disorders for ATP5C1 gene to outside databases
|
Publications
for ATP5C1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATP5C1 gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with ATP5C1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Gene structure of human mitochondrial ATP synthase gamma-subunit. Tissue specificity produced by alternative RNA splicing. (PubMed id 8227057)1, 2, 3, 9 Matsuda C.... Kagawa Y. (1993)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- Chromosomal localization of genes required for the terminal steps of oxidative metabolism: alpha and gamma subunits of ATP synthase and the phosphate carrier. (PubMed id 8168843)1, 3 Jabs E.W....Pedersen P.L. (1994)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
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External Searches for ATP5C1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing ATP5C1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ATP5C1 gene
(According to HUGE)
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Specialized Databases showing ATP5C1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for ATP5C1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for ATP5C1 gene:
Search GeneIP for patents involving ATP5C1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ATP5C1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | OriGene Antibodies for ATP5C1 | | OriGene shRNA RFP for ATP5C1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATP5C1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATP5C1 | | | OriGene Protein Over-expression Lysate for ATP5C1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATP5C1 | | OriGene 3'-UTR Clone for ATP5C1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5C1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATP5C1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ATP5C1 | | OriGene Custom Protein Services for ATP5C1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATP5C1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATP5C1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP5C1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATP5C1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATP5C1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATP5C1 |
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| | | | Search Tocris compounds for ATP5C1 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP5C1 |
|  |  |  |  | | | | ThermoFisher Antibody for ATP5C1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATP5C1 |
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