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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATP2C2 Gene

protein-coding   GIFtS: 61
GCID: GC16P084402

ATPase, Ca++ Transporting, Type 2C, Member 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ATPase, Ca++ Transporting, Type 2C, Member 21 2     EC 3.6.3.83 8
SPCA22 3 5     KIAA07033 5
Secretory Pathway Calcium ATPase 21 2     Calcium-Transporting ATPase Type 2C Member 22
Secretory Pathway Ca(2+)-ATPase 22 3     EC 3.6.38
ATPase 2C22 3     

External Ids:    HGNC: 291031   Entrez Gene: 99142   Ensembl: ENSG000000642707   OMIM: 6130825   UniProtKB: O751853   

Export aliases for ATP2C2 gene to outside databases

Previous GC identifers: GC16P082995 GC16P070154


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ATP2C2 Gene: 
ATP2C2 (ATPase, Ca++ transporting, type 2C, member 2) is a protein-coding gene. Diseases associated with ATP2C2 include language disorder, and skin conditions, and among its related super-pathways are Ion channel transport and SLC-mediated transmembrane transport. GO annotations related to this gene include calcium-transporting ATPase activity and metal ion binding. An important paralog of this gene is ATP2C1.

UniProtKB/Swiss-Prot: AT2C2_HUMAN, O75185
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium
(By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATP2C2 gene promoter:
         MyoD   HNF-3beta   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATP2C2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ATP2C2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP2C2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.1   Ensembl cytogenetic band:  16q24.1   HGNC cytogenetic band: 16q24.1

ATP2C2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP2C2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P084402:  view genomic region     (about GC identifiers)

Start:
84,402,133 bp from pter      End:
84,497,793 bp from pter
Size:
95,661 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AT2C2_HUMAN, O75185 (See protein sequence)
Recommended Name: Calcium-transporting ATPase type 2C member 2  
Size: 946 amino acids; 103187 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=BAA31678.2; Type=Erroneous initiation;
Secondary accessions: B4DU76 Q5S053 Q68CQ2
Alternative splicing: 2 isoforms:  O75185-1   O75185-2   (Ref.2 (BAA31678) sequence is in conflict in position: 12:R->I)

Explore the universe of human proteins at neXtProt for ATP2C2: NX_O75185

Explore proteomics data for ATP2C2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75185

  • 4/18 DME Specific Peptides for ATP2C2 (O75185) (see all 18)
     GDRIPAD  VKMITGD  GVVIGTG  AIPEGLP 

    ATP2C2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ATP2C2 Protein Expression
    REFSEQ proteins: NP_055676.2  
    ENSEMBL proteins: 
     ENSP00000262429   ENSP00000397925   ENSP00000456595  
    Reactome Protein details: O75185
    Human Recombinant Protein Products for ATP2C2: 
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    Cloud-Clone Corp. Proteins for ATP2C2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0016021integral to membrane IEA--

    ATP2C2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PATP: ATPases / P-type

    IUPHAR Guide to PHARMACOLOGY protein family classification: SPCA2 
    Ca2+-ATPases

    5/9 InterPro protein domains (see all 9):
     IPR023298 ATPase_P-typ_TM_dom
     IPR023299 ATPase_P-typ_cyto_domN
     IPR008250 ATPase_P-typ_transduc_dom_A
     IPR023214 HAD-like_dom
     IPR006413 ATPase_P-typ_Ca-transp_PMR1

    Graphical View of Domain Structure for InterPro Entry O75185

    ProtoNet protein and cluster: O75185

    4 Blocks protein domains:
    IPB000695 H+-transporting ATPase (proton pump) signature
    IPB001757 ATPase
    IPB006068 Cation transporting ATPase
    IPB008250 E1-E2 ATPase-associated region


    UniProtKB/Swiss-Prot: AT2C2_HUMAN, O75185
    Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily


    ATP2C2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AT2C2_HUMAN, O75185
    Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium
    (By similarity)
    Catalytic activity: ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)

         Enzyme Numbers (IUBMB): EC 3.6.3.81 2 EC 3.6.32

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005388calcium-transporting ATPase activity IEA--
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IEA--
    GO:0019829cation-transporting ATPase activity ----
         
    ATP2C2 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ATP2C2:
     Increased gamma-H2AX phosphory  Synthetic lethal with imatinib 

    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ATP2C2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ion channel transport
    Ion channel transport0.49
    Ion transport by P-type ATPases0.32
    2SLC-mediated transmembrane transport
    Transmembrane transport of small molecules0.50
    3calcium transport I
    calcium transport I

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for ATP2C2
        calcium transport I

    3        Reactome Pathways for ATP2C2
        Transmembrane transport of small molecules
    Ion channel transport
    Ion transport by P-type ATPases



    ATP2C2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP2C2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/9 Interacting proteins for ATP2C2 (O751851, 3 ENSP000002624294) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ORAI1Q96D311, 3, ENSP000003282164EBI-2939806,EBI-2291476 I2D: score=1 STRING: ENSP00000328216
    ATP2C1ENSP000003526654STRING: ENSP00000352665
    SOD2ENSP000003371274STRING: ENSP00000337127
    UBCENSP000003448184STRING: ENSP00000344818
    ATP13A1ENSP000003498774STRING: ENSP00000349877
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0006816calcium ion transport ----
    GO:0034220ion transmembrane transport TAS--
    GO:0055085transmembrane transport TAS--

    ATP2C2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ATP2C2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ATP2C2 (AT2C2)

    2 HMDB Compounds for ATP2C2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    MagnesiumMagnesium (see all 2)7439-95-4--

    2 Novoseek inferred chemical compound relationships for ATP2C2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    magnesium 33.6 1 2156817 (1)
    calcium 23.2 7 8334133 (1), 2156817 (1), 15677451 (1)

    Search CenterWatch for drugs/clinical trials and news about ATP2C2 / AT2C2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ATP2C2 gene: 
    NM_014861.2  

    Unigene Cluster for ATP2C2:

    ATPase, Ca++ transporting, type 2C, member 2
    Hs.6168  [show with all ESTs]
    Unigene Representative Sequence: AB014603
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262429 ENST00000416219(uc002fhx.3 uc010chj.3 uc002fhz.3)
    ENST00000565631(uc002fhy.3) ENST00000569207 ENST00000565546 ENST00000420010
    ENST00000565927 ENST00000568160 ENST00000563340 ENST00000564099 ENST00000567892
    ENST00000567222(uc002fia.3) ENST00000567629 ENST00000566874
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    Additional mRNA sequence: 

    AB014603.1 AK025424.1 AK091051.1 AK092737.1 AK300526.1 AK316128.1 AY358243.1 AY791884.1 
    BX648333.1 CR749829.1 

    14 DOTS entries:

    DT.97823470  DT.95265157  DT.92065082  DT.410539  DT.70103370  DT.101966546  DT.97841169  DT.40219232 
    DT.40244802  DT.95152694  DT.100009258  DT.102831665  DT.97765832  DT.92446316 

    24/81 AceView cDNA sequences (see all 81):

    BF508637 AA159011 AW009684 AI807594 BG403475 AW389305 AW072228 CB142295 
    CB068303 CA488631 BM043740 BE669626 AI660151 AW662634 AA976641 AI911077 
    BE219325 BQ315782 BF477597 BE612765 AK091051 AW291664 CR749829 AI808815 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ATP2C2 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^
    SP1:        -     -     -                                                                                                                                       
    SP2:                    -                 -                                                                                                                     
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 24a · 24b · 24c ^ 25 ^ 26a · 26b ^ 27a · 27b
    SP1:  -                                             
    SP2:  -                                             
    SP3:  -                                             
    SP4:                                                
    SP5:                                                


    ECgene alternative splicing isoforms for ATP2C2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATP2C2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTAACTACG
    ATP2C2 Expression
    About this image


    See ATP2C2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATP2C2

    SOURCE GeneReport for Unigene cluster: Hs.6168
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ATP2C2 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atp2c21 , 5 ATPase, Ca++ transporting, type 2C, member 21, 5 82.01(n)1
    84.73(a)1
      8 (68.21 cM)5
    690471  NM_026922.11  NP_081198.11 
     1197000095 
    chicken
    (Gallus gallus)
    Aves ATP2C21 ATPase, Ca++ transporting, type 2C, member 2 74.88(n)
    81.66(a)
      100859316  XM_003641929.1  XP_003641977.1 
    lizard
    (Anolis carolinensis)
    Reptilia ATP2C26
    Uncharacterized protein
    76(a)
    1 ↔ 1
    GL343849.1(33781-59617)
    fruit fly
    (Drosophila melanogaster)
    Insecta SPoCk6
    Secretory Pathway Calcium atpase
    49(a)
    1 → many
    3L(22742544-22780687)
    worm
    (Caenorhabditis elegans)
    Secernentea pmr-16
    Protein PMR-1, isoform c
    50(a)
    1 → many
    I(13004438-13023572)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PMA1(YGL008C)4 Plasma membrane H+-ATPase, pumps protons out of the more   --   7(482666-479910) 852876  NP_011507.1 


    ENSEMBL Gene Tree for ATP2C2 (if available)
    TreeFam Gene Tree for ATP2C2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ATP2C2 gene
    ATP2C12  ATP2A32  ATP2A22  ATP2A12  
    8 SIMAP similar genes for ATP2C2 using alignment to 3 protein entries:     AT2C2_HUMAN (see all proteins):
    DKFZp686I0955    ATP2C1    ATP2A2    ATP2A1    ATP1A2    DKFZp779O2152
    ATP2A3    DKFZp779G2251

    ATP2C2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3999 SNPs in ATP2C2 are shown (see all 3999)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1843181161,2
    --84400140(+) TGGCAC/TAATCT 1 -- us2k10--------
    rs1398302671,2
    --84400162(+) AACCTC/TCACCT 1 -- us2k10--------
    rs1498304481,2
    --84400234(+) CAGCAC/TACCTG 1 -- us2k10--------
    rs1886532331,2
    --84400250(+) TTTTTC/GTATTT 1 -- us2k10--------
    rs1816019221,2
    --84400276(+) TTTCCC/TCATGT 1 -- us2k10--------
    rs65640211,2
    C--84400353(+) gattaC/Gaggtg 1 -- us2k18Minor allele frequency- G:0.07NA WA CSA 14
    rs1401754341,2
    --84400379(+) AGCCTC/GCTCTA 1 -- us2k10--------
    rs1456919551,2
    --84400441(+) GCGCTC/TTGTTG 1 -- us2k10--------
    rs1475616131,2
    --84400463(+) TTGATC/GTAAGC 1 -- us2k10--------
    rs1171320601,2
    C,F--84400510(+) TCCCCC/TTCCAG 1 -- us2k11Minor allele frequency- T:0.03EA 120

    HapMap Linkage Disequilibrium report for ATP2C2 (84402133 - 84497793 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/27 variations for ATP2C2 (see all 27):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2659934CNV Deletion23128226
    esv2677840CNV Deletion23128226
    nsv907075CNV Loss21882294
    dgv2934n71CNV Loss21882294
    nsv907067CNV Loss21882294
    nsv517727CNV Loss19592680
    dgv169n21CNV Loss19592680
    nsv457598CNV Loss19166990
    nsv527957CNV Loss19592680
    nsv907074CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613082    OMIM disorders: --

    7 diseases for ATP2C2:    About MalaCards
    language disorder    skin conditions    hailey-hailey disease    dyslexia
    keratosis    migraine    tuberculosis

    3 diseases from the University of Copenhagen DISEASES database for ATP2C2:
    Hailey-Hailey disease     Dyslexia     Language disorder

    ATP2C2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ATP2C2
    Human Genome Epidemiology (HuGE) Navigator: ATP2C2 (4 documents)

    Export disorders for ATP2C2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATP2C2 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with ATP2C2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (1998)
    2. The secretory pathway Ca2+/Mn2+-ATPase 2 is a Golgi-localized pump with high affinity for Ca2+ ions. (PubMed id 15831496)1, 2, 9 Vanoevelen J.... Wuytack F. (2005)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. (PubMed id 18839057)1, 4 Lesch K.P....Jacob C. (2008)
    5. A high-density association screen of 155 ion transport genes for involvement with common migraine. (PubMed id 18676988)1, 4 Nyholt D.R....Palotie A. (2008)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. A novel isoform of the secretory pathway Ca2+,Mn(2+)-ATPase, hSPCA2, has unusual properties and is expressed in the brain. (PubMed id 15677451)1, 9 Xiang M....Rao R. (2005)
    8. CMIP and ATP2C2 modulate phonological short-term memo ry in language impairment. (PubMed id 19646677)1, 9 Newbury D.F....Monaco A.P. (2009)
    9. Genome-wide association analysis of blood biomarkers i n chronic obstructive pulmonary disease. (PubMed id 23144326)1 Kim D.K....Silverman E.K. (2012)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9914 HGNC: 29103 AceView: KIAA0703 Ensembl:ENSG00000064270 euGenes: HUgn9914
    ECgene: ATP2C2 H-InvDB: ATP2C2

    (According to HUGE)
    About This Section
    HUGE: KIAA0703

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATP2C2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ATP2C2 gene:
    Search GeneIP for patents involving ATP2C2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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