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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ATP1B2 Gene

protein-coding GIFtS: 60
GCID: GC17P007557

ATPase, Na+/K+ transporting, beta 2 polypeptide

Explore 17 diseases affiliated with
ATP1B2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
ATPase, Na+/K+ Transporting, Beta 2 Polypeptide¹ ²		Sodium Pump Subunit Beta-2²
AMOG¹ ² ⁵		Sodium-Potassium ATPase Subunit Beta 2 (Non-Catalytic)²
Sodium/Potassium-Dependent ATPase Subunit Beta-2² ³		Sodium/Potassium-Dependent ATPase Beta-2 Subunit²
Adhesion Molecule On Glia²		Sodium/Potassium-Transporting ATPase Beta-2 Chain²
Na, K-ATPase Beta-2 Polypeptide²		Sodium/Potassium-Transporting ATPase Subunit Beta-2²

External Ids:	HGNC: 805¹	Entrez Gene: 482²	Ensembl: ENSG00000129244⁷	OMIM: 182331⁵	UniProtKB: P14415³

Export aliases for ATP1B2 gene to outside databases

Previous GC identifers: GC17M008057 GC17P008294 GC17P007497 GC17P007755 GC17P007754 GC17P007494 GC17P007554 GC17P007448

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ATP1B2:

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the

subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and

maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential

for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical

excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a

smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the

number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by

multiple genes. This gene encodes a beta 2 subunit. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: AT1B2_HUMAN, P14415

Function: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with

the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known

summary for ATP1B2:

Na+,K+-ATPase is an ion pump responsible for maintaining sodium and potassium electrochemical gradients

across the plasma membrane.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010718.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ATP1B2 gene promoter:
AREB6 PPAR-gamma1 NF-1 RREB-1 MyoD PPAR-gamma2 POU3F2 YY1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ATP1B2 promoter sequence

Search SABiosciences Chromatin IP Primers for ATP1B2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP1B2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13.1

ATP1B2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP1B2 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P007557: view genomic region (about GC identifiers)

Start:	7,549,945 bp from pter	End:	7,561,089 bp from pter
Size:	11,145 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AT1B2_HUMAN, P14415 (See protein sequence)

Recommended Name: Sodium/potassium-transporting ATPase subunit beta-2

Size: 290 amino acids; 33367 Da

Subunit: Composed of three subunits: alpha (catalytic), beta and gamma

Subcellular location: Membrane; Single-pass type II membrane protein

Secondary accessions: A0AV17 A8K278 D3DTQ2 O60444

Explore the universe of human proteins at neXtProt for ATP1B2: NX_P14415

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P14415

ATP1B2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001669.3

ENSEMBL proteins:

ENSP00000459145 ENSP00000250111 ENSP00000460499

Reactome Protein details: P14415
Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005886	plasma membrane	TAS	--
GO:0016020	membrane	--	--
GO:0016021	integral to membrane	IEA	--

ATP1B2 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ATP1B2 for domains About GeneDecksing

1 InterPro domain/family:

IPR000402 Na/K_ATPase_sub_beta

Graphical View of Domain Structure for InterPro Entry P14415

ProtoNet protein and cluster: P14415

1 Blocks protein family: IPB000402 Na+/K+ ATPase

UniProtKB/Swiss-Prot: AT1B2_HUMAN, P14415

Similarity: Belongs to the X(+)/potassium ATPases subunit beta family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: AT1B2_HUMAN, P14415

Function: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with

the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known

Genatlas biochemistry entry for ATP1B2:

ATPase,Na+K+ beta 2 polypeptide,putative adhesion molecule on glia,specific

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		SwitchGear 3'UTR luciferase reporter plasmid: ATP1B2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP1B2

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005391	sodium:potassium-exchanging ATPase activity	IEA	--
GO:0005515	protein binding	IPI	11027149

ATP1B2 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for ATP1B2:

Increased G1 DNA content

Increased cell number in G1, a

Animal Models:
Mouse knock-out Atp1b2^tm1Msch for ATP1B2
5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Atp1b2):

behavior/neurological

cellular

mortality/aging

nervous system

vision/eye

ATP1B2 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/19 super-pathways (see all 19) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Ion channel transport

Ion channel transport

1.00

Ion transport by P-type ATPases

0.32

Gastric acid secretion

Gastric acid secretion

1.00

Salivary secretion

0.35

Basigin interactions

Basigin interactions

1.00

Cell surface interactions at the vascular wall

Cell surface interactions at the vascular wall

1.00

Sodium-coupled transporters and pumps

Sodium-coupled transporters and pumps

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for ATP1B2

Sodium-coupled transporters and pumps

2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for ATP1B2

	Hepatic ABC Transporters
	Aldosterone Signaling in Epithelial Cells

1 BioSystems Pathway for ATP1B2

Calcium Regulation in the Cardiac Cell

5/6 Reactome Pathways for ATP1B2 (see all 6)

	Hemostasis
	Transmembrane transport of small molecules
	Ion channel transport
	Basigin interactions
	Ion transport by P-type ATPases

5/11 Kegg Pathways (Kegg details for ATP1B2) (see all 11):

	Cardiac muscle contraction
	Aldosterone-regulated sodium reabsorption
	Endocrine and other factor-regulated calcium reabsorption
	Proximal tubule bicarbonate reclamation
	Salivary secretion

ATP1B2 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for ATP1B2

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/10 Interacting proteins for ATP1B2 (P14415³ ENSP00000250111⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NGB	Q9NPG2³, ENSP00000298352⁴	I2D: score=1 STRING: ENSP00000298352
DLG4	P78352³	I2D: score=1
RS1	O15537³	I2D: score=1
ATP1A1	ENSP00000295598⁴	STRING: ENSP00000295598
ATP1A2	ENSP00000354490⁴	STRING: ENSP00000354490

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006810	transport	TAS	2538450
GO:0007596	blood coagulation	TAS	--
GO:0034220	ion transmembrane transport	TAS	--
GO:0050900	leukocyte migration	TAS	--
GO:0055085	transmembrane transport	TAS	--

ATP1B2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

EMD Millipore small molecules for ATP1B2:
Small Molecule - inhibitor

Browse drugs & compounds from Enzo Life Sciences

Compounds for ATP1B2 available from Tocris Bioscience About this table

Compound	Action	CAS #
Ouabain	Na+,K+-ATPase inhibitor	[630-60-4]
Digoxin	Na+,K+-ATPase inhibitor	[20830-75-5]

7 HMDB Compounds for ATP1B2 About this table

Compound	Synonyms	CAS #	PubMed Ids
ADP	adenosindiphosphorsaeure (see all 8)	58-64-0	--
Adenosine triphosphate	5'-(tetrahydrogen triphosphate) Adenosine (see all 24)	56-65-5	--
Magnesium	Magnesium (see all 2)	7439-95-4	--
Phosphate	NFB Orthophosphate (see all 13)	14265-44-2	--
Potassium	K+ (see all 16)	7440-09-7	--
Sodium	Sodium (see all 2)	7440-23-5	--
Water	Dihydrogen oxide (see all 2)	7732-18-5	--

Search CenterWatch for drugs/clinical trials and news about ATP1B2 / AT1B2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ATP1B2 gene:

NM_001678.3

Unigene Cluster for ATP1B2:

ATPase, Na+/K+ transporting, beta 2 polypeptide

Hs.643540 [show with all ESTs]

Unigene Representative Sequence: NM_001678

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000577026 ENST00000250111(uc002gif.1) ENST00000577113

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		hsa-miR-3678-3p hsa-miR-1321 hsa-miR-1245 hsa-miR-877* hsa-miR-4314 hsa-miR-1184 hsa-miR-520g hsa-miR-3170

		SwitchGear 3'UTR luciferase reporter plasmid: ATP1B2 3' UTR sequence

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Additional cDNA sequence:

AK290143.1 AY946017.1 BC035801.1 BC126175.1 D87330.1 M81181.1 U45945.1

4 DOTS entries:

DT.92447964 DT.100811679 DT.115586 DT.92447966

24/160 AceView cDNA sequences (see all 160):

BM689476 H08829 BM674199 AI589796 AW131864 AI656367 NM_001678 F01423

BM661475 AA457385 AI085636 BM715871 AA457434 BE550304 AL120033 BC035801

BV184310 BM681927 AI214044 BU741790 BX508520 BM671338 CA436428 BM693371

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ATP1B2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTCTCTCTCT

About this image

ATP1B2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

10 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Spinal Cord

Spinal Ventral Columns

Ventral Spinal Cord Progenitor Cells

Motor Neurons

Brain

Kidney

Liver

Diencephalic Ventricular Zone

Neural Tube

Mesencephalic Ventricular Zone

Neural Tube

Metencephalon

Neural Tube

Spinal Cord

Presumptive Spinal Cord

Spinal Cord

Spinal Ventral Columns

Spinal Cord

Testis

Seminiferous Tubules

Testis

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ATP1B2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATP1B2

SOURCE GeneReport for Unigene cluster: Hs.643540

SABiosciences Custom PCR Arrays for ATP1B2

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP1B2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ATP1B2 gene from 5/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	ATP1B2⁶	--	61(a)	1 ↔ 1	GL343660.1(289295-302856)
African clawed frog (Xenopus laevis)	Amphibia	atp1b2-prov²	ATPase, Na+/K+ transporting, beta 2 polypeptide	77.53(n)		BC046269.1
zebrafish (Danio rerio)	Actinopterygii	atp1b2b²	ATPase, Na+/K+ transporting, beta 2b polypeptide	72.72(n)		114457 AF373976.1
fruit fly (Drosophila melanogaster)	Insecta	nrv1⁶ nrv3⁶ (see all 3)	nervana 3 (see all 3)	28(a) 26(a) (see all 3)	possible ortholog possible ortholog (see all 3)	2L(6778555-6786861) 2L(21380000-21393319)
worm (Caenorhabditis elegans)	Secernentea	nkb-3⁶ nkb-1⁶ (see all 3)	Probable sodium/potassium-transporting ATPase subu... Sodium/potassium-transporting ATPase subunit beta-... (see all 3)	25(a) 24(a) (see all 3)	possible ortholog possible ortholog (see all 3)	X(13765285-13770494) I(9431240-9433804)

ENSEMBL Gene Tree for ATP1B2 (if available)
TreeFam Gene Tree for ATP1B2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ATP1B2 gene

ATP1B3² ATP1B1² ATP1B4² ATP4B²

4 SIMAP similar genes for ATP1B2 using alignment to 4 protein entries: AT1B2_HUMAN (see all proteins):

ATP1B4 ATP4B ATP1B3 ATP1B1

ATP1B2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs149333815^1,2		--	7552259(+)	`CTGGGA/GTAGAC`	1	--	us2k¹		0	--	--	--	--
rs150588896^1,2		--	7552352(+)	`ACTCC-/CATT CATTC`	1	--	us2k¹		0	--	--	--	--
rs77700851^1,2	C	--	7552562(-)	`GAAACC/TCCATC`	1	--	us2k¹		3		NA CSA	7
rs113517139^1,2	C,	--	7552684(+)	`ACTGGG/CCCTGG`	1	--	us2k¹		2		WA	120
rs182181853^1,2		--	7552728(+)	`TGAGAC/TGAAGT`	1	--	us2k¹		0	--	--	--	--
rs144591431^1,2		--	7552791(+)	`AGCTCC/TGCCTC`	1	--	us2k¹		0	--	--	--	--
rs139371797^1,2		--	7552799(+)	`CTCCCA/GGGTTC`	1	--	us2k¹		0	--	--	--	--
rs186709985^1,2		--	7552887(+)	`TTTTTA/TTTATT`	1	--	us2k¹		0	--	--	--	--
rs1641514^1,2	C,H,	--	7552909(-)	`TGGGCG/AACAGA`	1	--	us2k¹		7		NA WA CSA	13
rs113626315^1,2	C,	--	7552931(+)	`AGTGGC/AGCGAT`	1	--	us2k¹		1		WA	2

HapMap Linkage Disequilibrium report for ATP1B2 (7549945 - 7561089 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ATP1B2: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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ATP1B2 for disorders           About GeneDecksing

OMIM gene information: 182331    OMIM disorders: --

17 diseases for ATP1B2:    About MalaCards

x-linked juvenile retinoschisis thyrotoxic periodic paralysis hemiplegic migraine familial hemiplegic migraine

retinoschisis migraine paralysis vaginitis

aldosteronism pulmonary disease ovarian cancer astrocytoma

breast cancer retinitis pancreatitis prostatitis

familial hemiplegic migraine type 2

Human Genome Epidemiology (HuGE) Navigator: ATP1B2 (7 documents)

Export disorders for ATP1B2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ATP1B2 gene, integrated from 9 sources (see all 38):
(articles sorted by number of sources associating them with ATP1B2)

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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Structure and expression of the human Na,K-ATPase beta 2-subunit gene. (PubMed id 9524271)^{1, 2} Avila J....Martin-Vasallo P. (1998)
Expression and synthesis of the Na,K-ATPase beta 2 subunit in human retinal pigment epithelium. (PubMed id 8918259)^{1, 2} Ruiz A.C.... Bok D. (1996)
Nucleotide sequence of a cDNA for the beta 2 subunit isoform of Na+,K(+)-ATPase from human retina. (PubMed id 8305453)^{1, 2} Hernando N....Coca-Prados M. (1994)
Assignment of Amog (adhesion molecule on glia) gene to mouse chromosome 11 near Zfp-3 and Asgr-1,2 and to human chromosome 17. (PubMed id 1699290)^{1, 3} Hsieh C.L....Francke U. (1990)
Identification of a putative isoform of the Na,K-ATPase beta subunit. Primary structure and tissue-specific expression. (PubMed id 2538450)^{1, 2} Martin-Vasallo P.... Levenson R. (1989)
Thyrotoxic periodic paralysis and polymorphisms of sodium-potassium ATPase genes. (PubMed id 16430714)^{1, 9} Kung A.W....Chan V. (2006)
Genome-wide association study of circulating estradiol , testosterone, and sex hormone-binding globulin in postmenopausal women. (PubMed id 22675492)¹ Prescott J....De Vivo I. (2012)
The Na/K-ATPase is obligatory for membrane anchorage of retinoschisin, the protein involved in the pathogenesis of X-linked juvenile retinoschisis. (PubMed id 21196491)¹ Friedrich U....Weber B.H. (2011)
Expression patterns of AMOG in developing human corte x and malformations of cortical development. (PubMed id 20656459)¹ Boer K....Aronica E. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 482	HGNC: 805	AceView: ATP1B2	Ensembl:ENSG00000129244	euGenes: HUgn482
ECgene: ATP1B2	Kegg: 482	H-InvDB: ATP1B2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ATP1B2	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for ATP1B2	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for ATP1B2 gene
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Patent Information for ATP1B2 gene:
Search GeneIP for patents involving ATP1B2

Licensable Technologies for ATP1B2 gene:

Weizmann Institute:

"Na, K-ATPase Isoforms and Selective Inhibitors Thereof"

GeneCards and IP:
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ATP1B2 Gene

ATPase, Na+/K+ transporting, beta 2 polypeptide

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ATP1B2 Gene

ATPase, Na+/K+ transporting, beta 2 polypeptide

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