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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATP13A2 Gene

protein-coding   GIFtS: 57
GCID: GC01M017312

ATPase Type 13A2

(Previous name: Parkinson disease (autosomal recessive) 9 (Kufor-Rakeb syndrome))
(Previous symbol: PARK9)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ATPase Type 13A21 2     Probable Cation-Transporting ATPase 13A22
PARK91 2 3 5     Putative ATPase2
KRPPD2 5     EC 3.6.3.-3
Parkinson Disease (Autosomal Recessive) 9 (Kufor-Rakeb Syndrome)1     EC 3.6.38
CLN122     EC 3.6.3.58
HSA99472     EC 3.6.3.88

External Ids:    HGNC: 302131   Entrez Gene: 234002   Ensembl: ENSG000001593637   OMIM: 6105135   UniProtKB: Q9NQ113   

Export aliases for ATP13A2 gene to outside databases

Previous GC identifers: GC01M017058 GC01M017185 GC01M015556


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ATP13A2 Gene:
This gene encodes a member of the P5 subfamily of ATPases which transports inorganic cations as well as other
substrates. Mutations in this gene are associated with Kufor-Rakeb syndrome (KRS), also referred to as Parkinson
disease 9. Multiple transcript variants encoding different isoforms have been found for this gene.(provided by
RefSeq, Nov 2008)

GeneCards Summary for ATP13A2 Gene: 
ATP13A2 (ATPase type 13A2) is a protein-coding gene. Diseases associated with ATP13A2 include parkinson disease type 9, and parkinsonim due to atp13a2 deficiency. GO annotations related to this gene include metal ion binding and ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism. An important paralog of this gene is ATP13A5.

UniProtKB/Swiss-Prot: AT132_HUMAN, Q9NQ11
Function: May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity

Gene Wiki entry for ATP13A2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004610.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATP13A2 gene promoter:
         p53   AML1a   Pax-5   LUN-1   GATA-1   Max   Pax-3   Ik-2   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATP13A2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ATP13A2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATP13A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36   Ensembl cytogenetic band:  1p36.13   HGNC cytogenetic band: 1p36

ATP13A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP13A2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M017312:  view genomic region     (about GC identifiers)

Start:
17,312,453 bp from pter      End:
17,338,423 bp from pter
Size:
25,971 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AT132_HUMAN, Q9NQ11 (See protein sequence)
Recommended Name: Probable cation-transporting ATPase 13A2  
Size: 1180 amino acids; 128794 Da
Subcellular location: Membrane; Multi-pass membrane protein (By similarity). Lysosome
Sequence caution: Sequence=CAA08912.1; Type=Frameshift; Positions=1054;
Secondary accessions: O75700 Q5JXY1 Q5JXY2 Q6S9Z9
Alternative splicing: 3 isoforms:  Q9NQ11-1   Q9NQ11-2   Q9NQ11-3   

Explore the universe of human proteins at neXtProt for ATP13A2: NX_Q9NQ11

Explore proteomics data for ATP13A2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NQ11

  • 4/10 DME Specific Peptides for ATP13A2 (Q9NQ11) (see all 10)
     TGESIPV  DKTGTLT  VPPALPA  SSLTGES 

    ATP13A2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ATP13A2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001135445.1  NP_001135446.1  NP_071372.1  

    ENSEMBL proteins: 
     ENSP00000327214   ENSP00000341115   ENSP00000413307   ENSP00000423065   ENSP00000421126  
     ENSP00000424393   ENSP00000424313   ENSP00000427241   ENSP00000422227   ENSP00000422668  

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    Cloud-Clone Corp. Proteins for ATP13A2 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005764lysosome IDA--
    GO:0005765lysosomal membrane IDA17897319
    GO:0016021integral to membrane IEA--

    ATP13A2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PARK: Parkinson disease
    PATP: ATPases / P-type

    5/7 InterPro protein domains (see all 7):
     IPR023299 ATPase_P-typ_cyto_domN
     IPR008250 ATPase_P-typ_transduc_dom_A
     IPR023214 HAD-like_dom
     IPR004014 ATPase_P-typ_cation-transptr_N
     IPR006544 ATPase_P-typ_Cation_typ_V

    Graphical View of Domain Structure for InterPro Entry Q9NQ11

    ProtoNet protein and cluster: Q9NQ11

    2 Blocks protein domains:
    IPB001757 ATPase
    IPB008250 E1-E2 ATPase-associated region


    UniProtKB/Swiss-Prot: AT132_HUMAN, Q9NQ11
    Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily


    ATP13A2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AT132_HUMAN, Q9NQ11
    Function: May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Numbers (IUBMB): EC 3.6.3.52 EC 3.6.3.82 EC 3.6.32 EC 3.6.3.-1

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IEA--
    GO:0016887ATPase activity ----
    GO:0019829cation-transporting ATPase activity IEA--
         
    ATP13A2 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Atp13a2):
     behavior/neurological  nervous system  pigmentation 

    ATP13A2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Atp13a2tm1Pjsch for ATP13A2

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ATP13A2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Neuroscience
    Neuroscience

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for ATP13A2
        Neuroscience



    ATP13A2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATP13A2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/11 Interacting proteins for ATP13A2 (Q9NQ111, 2, 3 ENSP000003272144) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CMTM6Q9NX762, 3, ENSP000002056364MINT-8252538 I2D: score=2 STRING: ENSP00000205636
    PRKCQQ047593I2D: score=2 
    AAK1Q2M2I81EBI-6308763,EBI-1383433
    BNIP3LO602381EBI-6308763,EBI-849893
    GAKO149761EBI-6308763,EBI-714707
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----

    ATP13A2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ATP13A2 (AT132)

    Search CenterWatch for drugs/clinical trials and news about ATP13A2 / AT132

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ATP13A2 gene (3 alternative transcripts): 
    NM_001141973.1  NM_001141974.1  NM_022089.2  

    Unigene Cluster for ATP13A2:

    ATPase type 13A2
    Hs.128866  [show with all ESTs]
    Unigene Representative Sequence: NM_022089
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000326735 ENST00000341676 ENST00000452699(uc001baa.2 uc001bab.2 uc001bac.2)
    ENST00000466561 ENST00000502418 ENST00000503552 ENST00000463860(uc009vpa.1 uc001bad.1)
    ENST00000502860 ENST00000509392 ENST00000506174 ENST00000510069 ENST00000511957
    ENST00000508222 ENST00000509619

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    Additional mRNA sequence: 

    AJ009947.1 AK025928.1 AK075310.1 AK290210.1 AL354615.1 AL833966.1 AY461712.1 AY987009.1 
    BC030267.1 BC034575.1 

    11 DOTS entries:

    DT.444266  DT.100039673  DT.100781975  DT.100781974  DT.100039674  DT.95283330  DT.95360628  DT.100039660 
    DT.95146554  DT.91712667  DT.95296187 

    24/154 AceView cDNA sequences (see all 154):

    BU195927 BU848987 BQ639456 CB215966 CD672722 BQ129344 BQ943018 AW503042 
    BQ068194 CK823571 R58916 BQ889151 BQ962923 NM_022089 BF001712 CR613271 
    BC034575 AW503046 CA418950 CF243131 BQ876431 AA326792 AL354615 BF725371 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for ATP13A2 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b · 15c · 15d ·
    SP1:                                                  -                             -                                   -                                   -   
    SP2:                                                                                -                                   -                                   -   
    SP3:                                                  -                             -                                   -                                   -   
    SP4:                                                                                                                    -                                       
    SP5:                                                                                                                                                            

    ExUns: 15e ^ 16 ^ 17 ^ 18a · 18b · 18c ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26a · 26b ^ 27a · 27b ^ 28 ^ 29a · 29b
    SP1:  -                                                                                               -                     
    SP2:  -                                                                                               -                     
    SP3:  -                                                     -                                         -     -               
    SP4:                                                                                                                        
    SP5:                                                                                                  -     -               


    ECgene alternative splicing isoforms for ATP13A2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATP13A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATATTTTCCT
    ATP13A2 Expression
    About this image


    See ATP13A2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATP13A2

    SOURCE GeneReport for Unigene cluster: Hs.128866

    UniProtKB/Swiss-Prot: AT132_HUMAN, Q9NQ11
    Tissue specificity: Expressed in brain; protein levels are markedly increased in brain from subjects with
    Parkinson disease and subjects with dementia with Lewy bodies. Detected in pyramidal neurons located throughout
    the cingulate cortex (at protein level). In the substantia nigra, it is found in neuromelanin-positive
    dopaminergic neurons (at protein level)

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ATP13A2 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atp13a21 , 5 ATPase type 13A21, 5 85.14(n)1
    86.23(a)1
      4 (73.29 cM)5
    747721  NM_029097.21  NP_083373.21 
     1409868735 
    chicken
    (Gallus gallus)
    Aves ATP13A26
    ATPase type 13A2
    59(a)
    1 ↔ 1
    21(4414089-4422658)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.27172 Xenopus laevis transcribed sequence with weak similarity more 76.58(n)    BJ060206.1 
    zebrafish
    (Danio rerio)
    Actinopterygii atp13a21 ATPase type 13A2 57.83(n)
    53.76(a)
      568666  NM_001080037.1  NP_001073506.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG320006
    --
    28(a)
    1 → many
    4(152846-163749)
    worm
    (Caenorhabditis elegans)
    Secernentea catp-76
    catp-66
    (see all 3)
    Probable cation-transporting ATPase W08D2.5
    (see all 3)
    34(a)
    33(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    IV(8585542-8594616)
    IV(9817411-9824632)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YPK96
    Vacuolar protein with a possible role in sequester...
    26(a)
    1 → many
    XV(861175-865593)


    ENSEMBL Gene Tree for ATP13A2 (if available)
    TreeFam Gene Tree for ATP13A2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ATP13A2 gene
    ATP13A52  ATP13A32  ATP13A42  
    3 SIMAP similar genes for ATP13A2 using alignment to 9 protein entries:     AT132_HUMAN (see all proteins):
    ATP13A4    ATP13A3    ATP13A5

    ATP13A2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    581/849 SNPs in ATP13A2 are shown (see all 849)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0660204
    Kufor-Rakeb syndrome (KRS)4--see VAR_0660202 G R mis40--------
    VAR_0660194
    Kufor-Rakeb syndrome (KRS)4--see VAR_0660192 F L mis40--------
    VAR_0660214
    Kufor-Rakeb syndrome (KRS)4--see VAR_0660212 L R mis40--------
    rs1426161301,2
    C,Funtested117529672(+) CCGCCG/AGTGTG 6 /R /W mis11Minor allele frequency- A:0.00NA 4546
    VAR_0584564
    ----see VAR_0584562 G R mis40--------
    rs563006341,2
    C--15570769(-) GGGGGG/AGCATG 3 -- int11Minor allele frequency- A:0.50WA 2
    rs1469315651,2
    C--15574247(+) TTTTC-/TTTTTTT 3 -- int10--------
    rs710064071,2
    C--17330162(+) TTTTC-/T/TT  
            
    TTTTT
    3 -- int12NA 4
    rs571218581,2
    C--17332749(+) TTTTT-/TGAGAC 3 -- int10--------
    rs674847891,2
    C--17334046(+) TTTTT-/TGAGAG 3 -- int11Minor allele frequency- T:0.00NA 2
    rs1995216491,2
    --17518216(+) CTCAA-/GGAAAA 3 -- ds50010--------
    rs788486251,2
    C--17518217(+) CTCAA-/G/GAA 
            
    AAAAA
    6 -- ds5001 cds10--------
    rs1140575531,2
    C,F--17518312(+) CAGGCC/TCAGAG 3 -- ds50011Minor allele frequency- T:0.05WA 118
    rs762989301,2
    C,F--17518555(+) CTACAC/TTGACA 4 M V ut31 mis11Minor allele frequency- T:0.02WA 118
    rs1855213591,2
    C--17518628(+) TAGTCA/GACGCT 4 V ut31 syn10--------
    rs1893344321,2
    C--17518656(+) GTCTCA/GGGGGA 4 P L ut31 mis10--------
    rs157861,2
    C,F,H--17518662(+) GGGGAG/AGAGTG 4 /P /L ut31 mis1 ese3 trp314Minor allele frequency- A:0.03MN NS EA NA 1704
    rs412731511,2
    C--17518666(+) AGGAGA/TGTAGA 4 T S ut31 mis10--------
    rs31707401,2
    C,F,A,H--17518813(-) TGGCCG/ACCGCT 6 /P /T /A syn1 mis1 ese312Minor allele frequency- A:0.46MN NA NS WA EA 606
    rs2016106811,2
    C--17518857(+) GAAGCA/GCTTCT 6 R C A V mis10--------
    rs1997752911,2
    --17518876(+) CGCTTG/TGGCCG 6 P K Q syn1 mis10--------
    rs1511816741,2
    C--17518899(+) GCAGGC/TGGGGA 6 T A H R mis10--------
    rs1390881701,2
    C--17518937(+) GGCAGA/GGAGGG 3 -- int10--------
    rs1159850121,2
    C,F--17519091(+) AAGCCG/AGTGTC 5 /T syn1 int13Minor allele frequency- A:0.00NA EU 5401
    rs1122614861,2
    C,F--17519106(+) ATGTTC/TCTCAG 5 R syn1 int12Minor allele frequency- T:0.00CSA NA 4490
    rs345852391,2
    C,F--17519111(+) CCTCAG/TCGCCA 5 M L mis1 int13Minor allele frequency- T:0.33NA 6
    rs2017561751,2
    C--17519119(+) CCAGCA/GGCCCC 5 P L mis1 int10--------
    rs20766051,2
    C,F--17519227(-) CGTGGC/TTCCTG 3 -- int19Minor allele frequency- T:0.34NA WA EA 370
    rs1498269871,2
    C--17519231(+) AGCCAC/TGCCCC 3 -- int10--------
    rs94357351,2
    C,F,A,H--17519284(+) CGGCCA/GGCACC 3 -- int11Minor allele frequency- G:0.00CSA 1
    rs563090441,2
    C--17519315(-) GAGGGAGGAGCC 
     CTGGG
    /-
    GTGCT
    6 -- int1 cds11Minor allele frequency- -:0.50CSA 2
    rs1434833511,2
    C--17519315(+) AGCAC-/CCCAG 
     GGCTCCT
    CCCTC
    3 -- int10--------
    rs1164568921,2
    C,F--17519349(+) TCTCCC/TGCCCG 3 -- int11Minor allele frequency- T:0.03WA 118
    rs561468401,2
    C--17519353(-) GGCGCG/AGGCGG 3 -- int13Minor allele frequency- A:0.02WA NA EU 357
    rs1378776651,2
    C,F--17519398(+) AAGGGC/TGCCCC 6 A syn11Minor allele frequency- T:0.00NA 4422
    rs94356591,2
    C,F--17519413(+) GACACG/AGCTGC 6 /A syn1 ese39Minor allele frequency- A:0.40NA WA EA EU 5683
    rs561262021,2
    C,F--17519461(-) AACACC/GGTGGT 6 T syn14Minor allele frequency- G:0.04WA NA EU 5871
    rs1848788971,2
    C--17519518(+) GGCACA/GAACCT 6 F syn10--------
    rs75311631,2
    C,F,A,H--17519524(+) AACCTG/AGGGGT 3 -- int122Minor allele frequency- A:0.27NS EA NA CSA WA EU 3632
    rs1884735621,2
    C--17519551(+) GGGAAC/TGAACG 3 -- int10--------
    rs2000458021,2
    --17519556(+) CGAACA/GTGGGG 3 -- int10--------
    rs558850471,2
    C,F--17519587(-) GACCAC/TCCCCA 3 -- int11Minor allele frequency- T:0.04EU 507
    rs2005374351,2
    C--17519651(+) CTGCAC/TCCGGT 6 M V mis11Minor allele frequency- T:0.00EU 1019
    rs2021663531,2
    --17519654(+) CACGCC/TGGTCA 6 S G mis10--------
    rs1455483161,2
    C,F--17519722(+) GTGGCC/TGCACC 6 Q R mis11Minor allele frequency- T:0.00NA 4408
    rs7614211,2
    C,F,A--17519724(-) CGGGTG/ACGGCC 6 /V syn1 ese311Minor allele frequency- A:0.40MN EA NA WA EU 7198
    rs1382127671,2
    C,F--17519742(+) ACCAGC/TGCTGG 6 A syn12Minor allele frequency- T:0.00NA EU 5533
    rs1482016081,2
    C,F--17519752(+) GCCCCG/ATGCGG 6 /T /M mis11Minor allele frequency- A:0.00NA 4508
    rs1810677401,2
    C--17519883(+) CCTGGA/CAGCCC 3 -- int10--------
    rs1471048221,2
    --17520056(+) CCTTGA/GGGGCC 3 -- int10--------
    rs94356601,2
    C,F,A,H--17520143(+) TCCCTA/GTAGCT 3 -- int121Minor allele frequency- G:0.29NS EA NA CSA WA 2347
    rs1477419031,2
    --17520158(+) GGGCAC/TGCACA 3 -- int10--------
    rs1167696161,2
    F--17520312(+) AGTAGG/CGTGTG 3 -- int11Minor allele frequency- C:0.03WA 118
    rs1146276631,2
    F--17520394(+) GGGGCG/AAGGGT 3 -- int11Minor allele frequency- A:0.03WA 118
    rs1165306551,2
    F--17520453(+) GAGTTG/TCGGTC 3 -- int11Minor allele frequency- T:0.03WA 118
    rs1859427931,2
    --17520479(+) GACAGA/CTGCTG 3 -- int10--------
    rs1491463351,2
    C--17520670(+) TGGGAC/TGGCTC 3 -- int10--------
    rs1445573041,2
    C--17520703(+) CTCACC/TGTGTA 6 T syn11Minor allele frequency- T:0.00NA 4552
    rs557089151,2,4
    C,F--17520726(-) AGTTCA/TTCTCC 6 I F mis12Minor allele frequency- T:0.00NA EU 5875
    rs37388151,2
    C,F,A,H--17520772(-) ACTTCG/ATTCAG 6 /S syn1 ese329Minor allele frequency- A:0.25EA NS NA CSA WA EU 10127
    rs1144073491,2
    C--17520815(+) GGGCAC/TGGACA 3 -- int12Minor allele frequency- T:0.00WA EU 711
    rs1432375681,2
    C--17520837(+) AGGTTG/TGCTGA 3 -- int10--------
    rs1483361701,2
    C--17520856(+) GCTGAG/ACCCTC 3 -- int11Minor allele frequency- A:0.00EU 1321
    rs1414474031,2
    C--17520858(+) TGAGCC/TCTCAC 3 -- int11Minor allele frequency- T:0.00EU 1317
    rs2014376221,2
    --17520861(+) GCCCTC/TACCCA 3 -- int10--------
    rs797242421,2
    C,F--17520925(+) ATGCTC/TGAGGT 6 S syn12Minor allele frequency- T:0.00WA NA 4670
    rs1454554521,2
    C,F--17520940(+) GGTGAG/CACCAC 6 /V syn12Minor allele frequency- C:0.00NA EU 5875
    rs1903236801,2
    C--17520986(+) CAGCCA/GCCTTC 6 A V mis10--------
    rs94356621,2
    C,F--17521012(+) TTGGCG/ACCGTC 6 /G syn1 ese312Minor allele frequency- A:0.41NA NS WA EA EU 6392
    rs1999949611,2
    C,F--17521030(+) ATGCCC/GACGCA 6 V syn11Minor allele frequency- G:0.00EU 1231
    rs1819074281,2
    C--17521083(+) CCCCAC/GCACCC 3 -- int10--------
    rs1145334141,2
    C,F--17521159(+) GGAGGC/TGCTCA 3 -- int11Minor allele frequency- T:0.03WA 118
    rs1379944141,2
    --17521160(+) GAGGCA/GCTCAG 3 -- int10--------
    rs1426798861,2
    --17521193(+) TTATTA/GTCATT 3 -- int10--------
    rs1460386331,2
    --17521290(+) CCTCCC/TGGGCT 3 -- int10--------
    rs75533401,2
    C,F,A--17521312(+) cctgcT/Ctcagc 3 -- int14Minor allele frequency- C:0.29NA CSA 7
    rs1492556211,2
    C--17521354(+) CACCAC/TGCCTG 3 -- int10--------
    rs1873654901,2
    --17521484(+) ATGAGA/CCACCG 3 -- int10--------
    rs49206051,2
    C,F--17521495(+) tgcccA/GgccTA 3 -- int13Minor allele frequency- G:0.33NA 6
    rs1156810321,2
    F--17521622(+) ATTACT/CGGTGT 3 -- int11Minor allele frequency- C:0.03WA 118
    rs1484294071,2
    --17521790(+) ACTATC/TTTTTG 3 -- int10--------
    rs1425474591,2
    --17521800(+) GAGACA/GGAGTC 3 -- int10--------
    rs1909778491,2
    C--17521858(+) TGCAGA/CCGCAG 3 -- int10--------
    rs1161316551,2
    F--17521860(+) CAGCCG/ACAGCC 3 -- int11Minor allele frequency- A:0.03WA 118
    rs2018840891,2
    --17521907(+) GAGTA-/GCTGG 
            
    GATGA
    3 -- int10--------
    rs1475139201,2
    --17521991(+) GGCTGC/GCCTCA 3 -- int10--------
    rs1401182251,2
    C--17522138(+) AGGGGC/TGACAG 3 -- int10--------
    rs1485341621,2
    F--17522272(+) TAGCTC/TGCACA 6 K E mis11Minor allele frequency- T:0.00NA 4534
    rs559298131,2
    C--17522391(-) CCTCAC/TGGCTC 3 -- int11Minor allele frequency- T:0.00EU 955
    rs2008098571,2
    --17522443(+) GGGGGC/TGGCCC 3 -- int10--------
    rs778807601,2
    C,F--17522647(+) GGGGTG/TGGGTC 3 -- int11Minor allele frequency- T:0.03WA 118
    rs1996552511,2
    C--17522712(+) GGCTGG/TGGGGG 6 T P mis10--------
    rs1827486241,2
    C--17522725(+) TCCATC/TGGCAG 6 P syn10--------
    rs1400481101,2
    C,F--17522737(+) AACTCG/AAGAGA 6 /L syn11Minor allele frequency- A:0.00NA 4536
    rs1379553091,2
    C,F--17522756(+) GACCCC/TGCTCA 6 Q R mis11Minor allele frequency- T:0.00NA 4512
    rs1447085041,2
    C,F--17522773(+) GTGGCG/ATGGAC 6 /H syn12Minor allele frequency- A:0.00NA EU 5753
    rs561700271,2,4
    C--17522778(-) TCATCA/C/GTCCAC 9 I L V mis11NA 4512
    rs776307881,2
    C--17522795(+) GCTCCG/TGGGGG 6 Q P mis10--------
    rs2009241941,2
    C--17522841(+) TGTCTG/CCAGGT 6 /Q /E mis11Minor allele frequency- C:0.00EU 1297
    rs562686511,2
    C--17522864(-) TGCCCC/TATAAC 3 -- int10--------
    rs1477580291,2
    C--17522891(+) CTATCC/TGGGGA 3 -- int10--------
    rs1999218591,2
    --17522892(+) TATCCA/GGGGAG 3 -- int10--------
    rs75354781,2
    C--17522932(+) GAAAAC/TAGGct 3 -- int10--------
    rs763406331,2
    C,F--17523037(+) GAAGGG/CTCTTA 3 -- int11Minor allele frequency- C:0.03EA 120
    rs1497745651,2
    --17523180(+) CTGGGC/TTCAAG 3 -- int10--------
    rs357269191,2
    C--17523250(+) GCTAA-/TTTTTT 3 -- int10--------
    rs1881184981,2
    C--17523278(+) GATGGG/TGTTTC 3 -- int10--------
    rs1166272681,2
    C,F--17523422(+) CTGCCA/GAGTGC 3 -- int11Minor allele frequency- G:0.05WA 118
    rs1903132041,2
    --17523465(+) AGGGGC/TGGGGA 3 -- int10--------
    rs1825773061,2
    C--17523576(+) ATGGCA/GTGATC 3 -- int10--------
    rs1875408261,2
    C--17523610(+) CCCGGC/GTTGAA 3 -- int10--------
    rs1456805321,2
    --17523613(+) GGGTTC/GAAGTG 3 -- int10--------
    rs1921149251,2
    --17523779(+) CCAAAC/GTGCTG 3 -- int10--------
    rs1489610821,2
    --17523785(+) TGCTGC/GGATTA 3 -- int10--------
    rs1140833241,2
    F--17523838(+) AGAGAC/TGGAGT 3 -- int11Minor allele frequency- T:0.07WA 118
    rs1456738751,2
    --17524085(+) CCACTA/CCTCTG 3 -- int10--------
    rs20766041,2
    C,F,A,H--17524135(-) CCGCAA/GGTGGT 3 -- int121Minor allele frequency- G:0.35EA NS NA CSA WA 3152
    rs560106351,2
    C,F--17524163(-) CATTTC/TGTGAA 3 -- int12Minor allele frequency- T:0.03WA 120
    rs1382947771,2
    --17524237(+) CCCCTC/TTTCTC 3 -- int10--------
    rs1857390881,2
    C--17524254(+) GAAGGA/GGCGGA 3 -- int10--------
    rs3733009931,2
    C--17524257(+) GGGGCA/GGATTC 3 -- int10--------
    rs1410588931,2
    C--17524267(+) CTGCCC/TTGCTA 3 -- int10--------
    rs1472777431,2,4
    C--17524314(+) GACGGC/TGCGGA 6 T A mis11Minor allele frequency- T:0.00NA 4550
    rs2018834641,2
    C--17524352(+) CTGGCG/ATTGTC 6 /T /M mis11Minor allele frequency- A:0.00EU 1323
    rs1482751811,2
    C--17524360(+) GTCTGC/AGGCTT 6 /P syn11Minor allele frequency- A:0.00NA 4552
    rs619993171,2
    C,F--17524390(+) AGCAGC/ACCCAG 6 /G syn12Minor allele frequency- A:0.00NS NA 4626
    rs2010388681,2
    --17524416(+) TTCCAC/GAGTGT 6 L V mis10--------
    rs2005854071,2
    --17524436(+) GTGGGC/TAGACC 3 -- int10--------
    rs578091551,2
    C--17524518(+) CCTGCA/GTGAGA 3 -- int10--------
    rs2020619991,2
    --17524530(+) CCTCCC/TTCTGC 3 -- int10--------
    rs617349581,2
    C,F--17524607(+) TGGGCA/GCAGTG 6 A V mis13Minor allele frequency- G:0.01NS WA NA 4664
    rs1438285471,2
    F--17524657(+) GCAGCT/CGTATA 6 /T syn11Minor allele frequency- C:0.00NA 4538
    rs1438345461,2
    C,F--17524680(+) CTGGGC/TGAAGT 6 T A mis11Minor allele frequency- T:0.00NA 4544
    rs2012368951,2
    --17524857(+) TTGACA/GTAGGC 6 Y syn10--------
    rs2009166731,2
    C--17524887(+) GGCCAC/TGCCAC 6 A syn10--------
    rs562147481,2
    C--17524995(-) KCCAGA/C/G/
            
    ACCTC
    3 -- int11CSA 1
    rs2015842881,2
    --17525029(+) GCACCC/TAACAG 3 -- int10--------
    rs2005299931,2
    --17525053(+) CACCAC/TTGCCT 6 M V mis10--------
    rs1889640681,2
    --17525074(+) CTCCCA/CAAGTG 6 G W mis10--------
    rs20766031,2
    C,F--17525081(-) AGACCC/G/TCCACT 9 P syn1 ese315EA NS NA WA CSA EU 7414
    rs125640401,2
    C,H--17525127(+) CTGCAG/TCCGGC 6 D A mis1 ese31Minor allele frequency- T:0.50NA 2
    rs2001841461,2
    --17525141(+) TCCTCC/TAGGAC 6 L syn10--------
    rs1924468841,2
    --17525214(+) GACTCA/GGGGAA 3 -- int10--------
    rs1845244661,2
    C--17525334(+) GAATAC/TGTCAC 3 -- int10--------
    rs49206081,2
    C,F,A,H--17525357(+) AGCCTC/TAGCAT 3 -- int120Minor allele frequency- T:0.45NS EA NA WA 2336
    rs779675661,2
    C,F--17525443(+) CTGGCG/ACATAG 3 -- int11Minor allele frequency- A:0.03WA 118
    rs1880332271,2
    C--17525564(+) CAACCA/TCTGCC 3 -- int10--------
    rs1507238071,2
    --17525693(+) GCCAGA/GCTGCT 3 -- int10--------
    rs1378682311,2
    --17525709(+) ACTTCC/TGACCT 3 -- int10--------
    rs1494528981,2
    --17525840(+) CAGTAA/GCGTGA 3 -- int10--------
    rs1471744111,2
    C--17525874(+) CTCCCA/GGGCTC 3 -- int10--------
    rs1812043341,2
    C--17525946(+) TTTTGC/TATTTT 3 -- int10--------
    rs2020225731,2
    --17526161(+) GCCCAC/GAGGCA 3 -- int10--------
    rs740583641,2
    C--17526192(+) TCCTCC/ACCCAG 3 -- spd11Minor allele frequency- A:0.50WA 2
    rs2008684841,2
    --17526239(+) CCCACA/GGGGGT 6 P syn10--------
    rs2003372901,2
    --17526309(+) GCAGGC/TGGCGA 6 H R mis10--------
    rs617397521,2
    C,F--17526326(+) GGGACC/AAGGGG 6 /L syn13Minor allele frequency- A:0.02NS WA NA 2738
    rs563518171,2
    C,F--17526329(-) CTGCCC/TCTGGT 6 P syn11Minor allele frequency- T:0.00NA 2626
    rs1838422971,2
    C--17526426(+) GGGCAC/GCGATG 3 -- int10--------
    rs1891031891,2
    --17526600(+) CCACCA/GTCTCT 3 -- int10--------
    rs1456017461,2
    --17526733(+) GACCCA/GGCCCA 3 -- int10--------
    rs728994281,2
    C,F--17526739(+) GCCCAC/TGGTTG 3 -- int12Minor allele frequency- T:0.19WA 120
    rs1447103701,2
    C--17526749(+) GCTCG-/CTCT  
      CTCTCT
    CTCTC
    3 -- int10--------
    rs2015260771,2
    --17526751(+) TCGCT-/CGCTCTC 3 -- int10--------
    rs3744664941,2
    C--17526788(+) ATTTA-/TTTTTAT 3 -- int10--------
    rs1818810731,2
    --17526821(+) GAGATA/GGAGTC 3 -- int10--------
    rs1873309721,2
    --17526884(+) CCTCCA/TCCTCC 3 -- int10--------
    rs1922264721,2
    --17526987(+) GAGACA/GGGGTT 3 -- int10--------
    rs1819686991,2
    --17527116(+) TGAATA/GAGCGC 3 -- int10--------
    rs1148901311,2
    F--17527240(+) TATTTT/ATTTTT 3 -- int11Minor allele frequency- A:0.03WA 118
    rs561179081,2
    C--17527278(+) GCTGGA/GGTGCA 3 -- int10--------
    rs568382201,2
    C,F--17527341(+) TCCTGC/ACCCAG 3 -- int11Minor allele frequency- A:0.50WA 2
    rs1854050151,2
    --17527487(+) CTCCCA/GAAGTG 3 -- int10--------
    rs104370471,2
    C,F,A,H--17527498(+) CCGGGA/TTTCCA 3 -- int19Minor allele frequency- T:0.13NS EA CSA WA NA 759
    rs1896679391,2
    C--17527519(+) ACTGCC/GCTGGG 3 -- int10--------
    rs795018011,2
    C,F--17527582(+) ACCTAG/ACCTCT 3 -- int11Minor allele frequency- A:0.03EA 120
    rs770150931,2
    F--17527692(+) CACACG/AGTACA 3 -- int11Minor allele frequency- A:0.02WA 118
    rs1828142001,2
    --17527740(+) TCCTCA/GACCTG 3 -- int10--------
    rs1166187061,2
    F--17527890(+) AGCAGC/TTCCTT 3 -- int11Minor allele frequency- T:0.03WA 118
    rs1134404931,2
    C,F--17528010(+) TGCACG/ACTAGG 3 -- int11Minor allele frequency- A:0.50NA 2
    rs1512526031,2
    --17528058(+) AGTTTC/TGCTCT 3 -- int10--------
    rs1404640181,2
    --17528079(+) CTGGAA/GTACAA 3 -- int10--------
    rs1442003811,2
    --17528137(+) CCTCCC/TGAGTA 3 -- int10--------
    rs792589021,2
    C,F--17528467(+) AATAAC/TGCGGG 3 -- int11Minor allele frequency- T:0.02WA 118
    rs2021769031,2
    --17528507(+) TGTCCC/TGCTCC 3 -- int10--------
    rs2016720211,2
    --17528647(+) TGCACA/GCAGTC 6 A V mis10--------
    rs1504698161,2
    F--17528704(+) GAGCCC/TGGATT 6 Q R mis11Minor allele frequency- T:0.00NA 4540
    rs1465889891,2
    C--17528753(+) AATGTA/GAGCAC 3 -- int10--------
    rs2007969901,2
    C--17528760(+) GCACCC/TGGCTG 3 -- int10--------
    rs1998145311,2
    --17528778(+) CCTGGG/TCCCTG 3 -- int10--------
    rs1385462751,2
    C,F--17528820(+) TTACCC/TGGTTT 6 Q R mis11Minor allele frequency- T:0.00NA 4544
    rs1493729691,2
    C,F--17528863(+) GAGGAG/CAGCTG 6 /L /V mis12Minor allele frequency- C:0.00NA EU 5859
    rs1404368681,2
    C--17528909(+) CAGGT-/GGGGGG 3 -- int10--------
    rs1871386191,2
    --17528909(+) CAGGTC/GGGGGG 3 -- int10--------
    rs1907460401,2
    --17529013(+) TGGGCC/TGGGGG 6 Q R mis10--------
    rs2008961091,2
    C--17529075(+) GAGGCA/GGGGAC 3 -- int10--------
    rs1835905841,2
    --17529140(+) GACCCA/GTGCCT 3 -- int10--------
    rs20766021,2
    C,F,H--17529268(-) GTGTTT/AAGATG 3 -- int113Minor allele frequency- A:0.43EA NS NA CSA WA 2072
    rs562746091,2
    C--17529338(+) TGCCCG/ACTCCA 3 -- int13Minor allele frequency- A:0.11NA WA 240
    rs1882273031,2
    --17529341(+) CCGCTA/CCAGCA 3 -- int10--------
    rs1160584171,2
    F--17529386(+) GCTTGG/CCCTTA 3 -- int11Minor allele frequency- C:0.07NA 120
    rs556827041,2
    C--17529436(-) CCCCCC/-ATCTG 3 -- int11Minor allele frequency- -:0.50CSA 2
    rs560687171,2
    C,F--17529503(-) GACCTG/AGAACC 3 -- int12Minor allele frequency- A:0.18WA 120
    rs94357361,2
    C,F,H--17529519(+) CTGCCC/TCACTC 3 -- int124Minor allele frequency- T:0.20NS EA NA WA CSA 2352
    rs2000242371,2
    --17529549(+) GAGCCC/TGGGAT 3 -- int10--------
    rs556890041,2
    C--17529575(-) GAGCCA/GGGAGG 3 -- int10--------
    rs1177589871,2
    C,F--17529576(+) CTCCCG/AGCTCA 3 -- int11Minor allele frequency- A:0.03EA 120
    rs1131056671,2
    C,F--17529609(+) CAGGAC/TGTGCG 6 I V mis12Minor allele frequency- T:0.00CSA NA 4484
    rs2016614801,2
    --17529610(+) AGGACA/GTGCGG 6 H syn10--------
    rs1489700811,2
    C--17529652(+) GTCCCG/ACAGAA 6 /C syn12Minor allele frequency- A:0.00NA EU 5139
    rs559431001,2
    C,F--17529700(-) GAGGGG/CCTGGG 6 /G syn11Minor allele frequency- C:0.00NA 4540
    rs1932733731,2
    --17529823(+) TCCCAC/TAAGCT 3 -- int10--------
    rs1853709481,2
    --17529843(+) AGTTAA/CCTCTG 3 -- int10--------
    rs94356641,2
    F--17529982(+) AGCGGG/CGGGGG 3 -- int11Minor allele frequency- C:0.09WA 118
    rs1995908531,2
    --17529985(+) GGGGG-/GGGGT 
            
    GGGTC
    3 -- int10--------
    rs1121959331,2
    C--17529989(+) GGGGGG/TGGGTC 3 -- int11Minor allele frequency- T:0.50WA 2
    rs1385701681,2
    C--17529999(+) CAGACA/GGAGCA 3 -- int10--------
    rs1164889261,2
    C,F--17530048(+) AGTCGT/CTCTCT 3 -- int11Minor allele frequency- C:0.11NA 120
    rs1159998081,2
    C,F--17530072(+) ATTTTA/GTAACA 3 -- int11Minor allele frequency- G:0.02NA 120
    rs1866950111,2
    --17530263(+) TAGCCA/GGGTGT 3 -- int10--------
    rs1139989481,2
    F--17530267(+) CGGGTG/ATTGTG 3 -- int11Minor allele frequency- A:0.03WA 118
    rs1912515361,2
    C--17530491(+) GGAGGA/GGGCAA 3 -- int10--------
    rs94356651,2
    C,F--17530607(+) TGCAGG/ACTGGG 3 -- int16Minor allele frequency- A:0.25NA CSA WA EA 364
    rs1128396541,2
    C--17530623(+) TGAGCG/ACCTAC 3 -- int11Minor allele frequency- A:0.50CSA 2
    rs745856541,2
    C--17530650(+) CAAGGG/TAGTCA 3 -- int10--------
    rs740583651,2
    C,F--17530704(+) GTATGC/TGTGGA 3 -- int11Minor allele frequency- T:0.50WA 2
    rs1841671741,2
    C--17530737(+) AGGGCA/GTGTGC 3 -- int10--------
    rs1480541971,2
    --17530816(+) CCAGGC/TTGGAG 3 -- int10--------
    rs127240291,2
    C,F,A--17530828(+) GCAGTG/CGTGCG 3 -- int14Minor allele frequency- C:0.50NA WA 8
    rs1471382461,2
    --17530865(+) CCTAGA/GCTCAA 3 -- int10--------
    rs1387369971,2
    --17530882(+) CTCCCA/GCCTCA 3 -- int10--------
    rs1167146221,2
    F--17531074(+) CCTACG/AATTTG 3 -- int11Minor allele frequency- A:0.05WA 118
    rs1506727581,2
    --17531242(+) TGTGGC/TGTCCT 3 -- int10--------
    rs1398473901,2
    --17531320(+) CATCCA/GTATTG 3 -- int10--------
    rs1126156481,2
    C,F--17531467(+) ACACAC/TGTAAT 3 -- int13Minor allele frequency- T:0.04WA CSA 122
    rs1493999191,2
    --17531566(+) GGACCA/GCAGTC 3 -- int10--------
    rs1448642141,2
    --17531628(+) TGACCC/TGAAGG 3 -- int10--------
    rs1884695041,2
    --17531772(+) GAAACC/TCCATC 3 -- int10--------
    rs1485831661,2
    --17531804(+) GCCGGG/TTATGG 3 -- int10--------
    rs679691841,2
    C--17531970(+) AAAAA-/A/GGGAGA 3 -- int11NA 2
    rs94356671,2
    C--17531971(+) AAAAAG/AGAGAA 3 -- int1 trp31Minor allele frequency- A:0.50NA 2
    rs672102741,2
    C--17531971(+) AAAAA-/GGAGAA 3 -- int10--------
    rs66847701,2
    C,F,A,H--17532025(+) CTCACG/ACTCCT 3 -- int126Minor allele frequency- A:0.34NS EA NA WA CSA 2764
    rs1442073311,2
    --17532061(+) GAGGAA/GTGACT 3 -- int10--------
    rs115839231,2
    C,H--17532201(+) CTGGCT/ACACGC 3 -- int113Minor allele frequency- A:0.03NA WA CSA EA 375
    rs115831481,2
    C,H--17532241(+) GTGGGT/CAGATA 3 -- int18Minor allele frequency- C:0.00NA WA CSA 14
    rs1929719031,2
    --17532274(+) CCAGCC/TTGGGC 3 -- int10--------
    rs1853473901,2
    --17532297(+) CTCCAC/TCTCTA 3 -- int10--------
    rs562904061,2
    C,F--17532610(-) GTGGCC/TGGCGA 6 A syn14Minor allele frequency- T:0.04WA NA EU 4735
    rs1483911791,2
    C,F--17532664(+) ACCAGG/ACAGTC 6 /C syn12Minor allele frequency- A:0.00NA EU 5295
    rs2003908001,2
    --17532699(+) CACCCA/GCTCTT 6 R W mis10--------
    rs1400875271,2
    C--17532859(+) TCCTGA/CCCCCG 3 -- int10--------
    rs2011498941,2
    --17532890(+) CACCTA/CCCCCT 6 G V mis10--------
    rs563670691,2,4
    C,F--17532914(-) CATGCG/AGGTGT 6 /Q /R mis11Minor allele frequency- A:0.01NA 3176
    rs1448982391,2
    C--17532915(+) CACCCG/ACATGG 6 /R /W mis11Minor allele frequency- A:0.00NA 3200
    rs1125495901,2
    C--17532958(+) TGCTGC/TGGGCA 3 -- int11Minor allele frequency- T:0.50CSA 2
    rs2003826601,2
    C--17533016(+) GTCCCA/GTCCCC 3 -- int10--------
    rs1455150281,2
    C,F--17533136(+) ACAGCG/ACGATG 6 /A /V mis12Minor allele frequency- A:0.00NA EU 5423
    rs1996617931,2
    C--17533137(+) CAGCGC/TGATGC 6 T A mis10--------
    rs1512697091,2
    C--17533209(+) GGGCCA/GCGTCC 3 -- int10--------
    rs562285841,2
    C--17533244(-) ACAGRA/TGACCC 3 -- int10--------
    rs561872401,2
    C--17533245(-) CACAGA/GWGACC 3 -- int10--------
    rs1807839381,2
    C--17533359(+) TTCTCC/TGCTCT 3 -- int10--------
    rs1403254151,2
    --17533413(+) ACCCCA/GTATCT 3 -- int10--------
    rs603174211,2
    C,F--17533523(+) AGGGTG/ACAGTG 3 -- int11Minor allele frequency- A:0.50WA 2
    rs1451369041,2
    --17533540(+) GATCGC/TGCCAC 3 -- int10--------
    rs75507581,2
    C,F,A,H--17533576(+) gagacC/Tctgtc 3 -- int17Minor allele frequency- T:0.42NA EA 252
    rs1858326041,2
    --17533581(+) CCTGTC/TTCAAA 3 -- int10--------
    rs1120143021,2
    C--17533651(+) AGTGCC/TTTATC 3 -- int11Minor allele frequency- T:0.50CSA 2
    rs94356681,2
    C,F--17533666(+) TGTCAT/CACAAT 3 -- int11Minor allele frequency- C:0.11WA 118
    rs1914737171,2
    --17533889(+) TCCCCA/GTATCT 3 -- int10--------
    rs49203731,2
    C--17533904(+) aaaatA/Ccaaaa 3 -- int11Minor allele frequency- C:0.00NA 2
    rs593055261,2
    C--17533920(+) AAAAA-/AAAAA 
    /AAAAAAA
    TTAGC
    3 -- int11NA 2
    rs1457737681,2
    C--17533989(+) CACTTA/GAACCC 3 -- int10--------
    rs1175611641,2
    F--17534007(+) GGACAT/ACGCAG 3 -- int11Minor allele frequency- A:0.03EA 120
    rs66576131,2
    C,F,A,H--17534347(+) ATGAAA/TGTGGA 3 -- int112Minor allele frequency- T:0.31NS EA NA WA 784
    rs1173543761,2
    C,F--17534357(+) AGGACG/ACACAG 3 -- int11Minor allele frequency- A:0.03EA 120
    rs28717761,2
    C,F,A,H--17534448(-) CACTCG/ATAGGG 3 -- int124Minor allele frequency- A:0.35NS EA NA WA CSA 2354
    rs1828436341,2
    --17534462(+) CCCCAA/GTCTGT 3 -- int10--------
    rs1869758881,2
    --17534499(+) ATTCCC/TGGACC 3 -- int10--------
    rs740583681,2
    C,F--17534548(+) ATGACG/AATCCA 3 -- int12Minor allele frequency- A:0.03WA 120
    rs2016307491,2
    --17534636(+) CAGCAC/TGCCAG 3 -- int10--------
    rs412731531,2
    C--17534665(+) CCAGGA/GACAGC 3 -- int10--------
    rs1495484011,2
    F--17534679(+) ACCTCG/ATCCAC 6 /D syn11Minor allele frequency- A:0.00NA 4506
    rs1131161111,2
    C--17534834(+) CTGGGA/GGAACT 3 -- int11Minor allele frequency- G:0.00CSA 1
    rs563277811,2
    C,F--17534878(-) CCCCAA/GTGTGG 3 -- int11Minor allele frequency- G:0.07NA 120
    rs1473842481,2
    C--17534985(+) TGGACG/ATCGTC 6 /D syn11Minor allele frequency- A:0.00NA 4278
    rs2020516301,2
    C--17535040(+) GACACA/GCATGG 3 -- int10--------
    rs1914100521,2
    --17535328(+) AGTCAC/TTTAAC 3 -- int10--------
    rs1159331771,2
    C,F--17535332(+) ACTTAA/GCCTCT 3 -- int11Minor allele frequency- G:0.01NA 120
    rs1834323701,2
    --17535426(+) GCCTCG/TGGGAC 3 -- int10--------
    rs1386279571,2
    --17535453(+) GCCACA/TTGCTA 3 -- int10--------
    rs1137644521,2
    C--17535587(+) TTACCA/TGAGGC 3 -- int11Minor allele frequency- T:0.00CSA 1
    rs799516601,2
    C,F--17535638(+) AGCGTG/AGAAGA 3 -- int11Minor allele frequency- A:0.01NA 120
    rs1427603911,2
    --17535757(+) CAGGCA/GACTGA 3 -- int10--------
    rs1435168331,2
    --17535768(+) AGTCCA/GGGTGT 3 -- int10--------
    rs1480021321,2
    --17535777(+) GTCCAA/CAGCTG 3 -- int10--------
    rs1877531961,2
    --17535817(+) TCCATC/TCCTTC 3 -- int10--------
    rs1415431261,2
    --17535962(+) TGGGAC/GGCTGA 3 -- int10--------
    rs1508668481,2
    C--17535971(+) GAGGCA/GGGTGG 3 -- int10--------
    rs1397596661,2
    --17535973(+) GGCGGG/TTGGAT 3 -- int10--------
    rs1430316811,2
    --17536115(+) GAATCA/GCTTGA 3 -- int1