Aliases for ATP11C Gene
External Ids for ATP11C Gene
Previous GeneCards Identifiers for ATP11C Gene
GeneCards Summary for ATP11C Gene
ATP11C (ATPase Phospholipid Transporting 11C) is a Protein Coding gene. Diseases associated with ATP11C include Congenital Hemolytic Anemia. Among its related pathways are Cardiac conduction and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include nucleotide binding and cation-transporting ATPase activity. An important paralog of this gene is ATP11A.
UniProtKB/Swiss-Prot for ATP11C Gene
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Required for B cell differentiation past the pro-B cell stage. Seems to mediate phosphatidylserine (PS) flipping in pro-B cells. May be involved in the transport of cholestatic bile acids (By similarity).