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ATP11B Gene

protein-coding   GIFtS: 56
GCID: GC03P182511

ATPase, Class VI, Type 11B

(Previous names: ATPase, Class VI, type 11B)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ATPase, Class VI, Type 11B1 2     Probable Phospholipid-Transporting ATPase IF2
ATPIR2 3 5     Truncated ATPase 11B Protein2
ATPIF2 3     KIAA09563
ATPase IR2 3     ATPase Class VI Type 11B3
EC 3.6.3.13 8     EC 3.6.38

External Ids:    HGNC: 135531   Entrez Gene: 232002   Ensembl: ENSG000000580637   OMIM: 6058695   UniProtKB: Q9Y2G33   

Export aliases for ATP11B gene to outside databases

Previous GC identifers: GC03P179338 GC03P183431 GC03P183979 GC03P183832 GC03P183993 GC03P179916


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ATP11B Gene:
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions
across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy
metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+),
K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.(supplied by OMIM, Feb 2005)

GeneCards Summary for ATP11B Gene:
ATP11B (ATPase, class VI, type 11B) is a protein-coding gene. GO annotations related to this gene include phospholipid-translocating ATPase activity and magnesium ion binding. An important paralog of this gene is ATP11A.

Gene Wiki entry for ATP11B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ATP11B gene promoter:
         STAT1   STAT4   STAT1beta   STAT5A   STAT1alpha   MEF-2A   STAT2   STAT3   aMEF-2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATP11B promoter sequence
   Search Chromatin IP Primers for ATP11B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ATP11B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q27   Ensembl cytogenetic band:  3q26.33   HGNC cytogenetic band: 3q27

ATP11B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATP11B gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P182511:  view genomic region     (about GC identifiers)

Start:
182,511,288 bp from pter      End:
182,639,423 bp from pter
Size:
128,136 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: AT11B_HUMAN, Q9Y2G3 (See protein sequence)
Recommended Name: Probable phospholipid-transporting ATPase IF  
Size: 1177 amino acids; 134190 Da
Subunit: Interacts with TMEM30A
Sequence caution: Sequence=AAH10630.1; Type=Frameshift; Positions=884; Sequence=AAH42180.1; Type=Miscellaneous
discrepancy; Note=Intron retention;
Secondary accessions: Q96FN1 Q9UKK7

Explore the universe of human proteins at neXtProt for ATP11B: NX_Q9Y2G3

Explore proteomics data for ATP11B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ATP11B (Q9Y2G3) (see all 13)
     GNWTFGT  LFEQFRR  NDVSMIQ  DKTGTLT 


    See ATP11B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055431.1  
    ENSEMBL proteins: 
     ENSP00000321195   ENSP00000419032   ENSP00000418421   ENSP00000417406   ENSP00000417124  
     ENSP00000419768   ENSP00000419152  
    Reactome Protein details: Q9Y2G3

    ATP11B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ATP11B

     
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    antibodies-online proteins for ATP11B (2 products) 

     
    antibodies-online peptides for ATP11B

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PATP: ATPases / P-type

    IUPHAR Guide to PHARMACOLOGY protein family classification: ATP11B
    Phospholipid-transporting ATPase

    Selected InterPro protein domains (see all 6):
     IPR008250 ATPase_P-typ_transduc_dom_A
     IPR023214 HAD-like_dom
     IPR006539 ATPase_P-typ_Plipid-transp
     IPR001757 Cation_transp_P_typ_ATPase
     IPR018303 ATPase_P-typ_P_site

    Graphical View of Domain Structure for InterPro Entry Q9Y2G3

    ProtoNet protein and cluster: Q9Y2G3

    1 Blocks protein domain: IPB001757 ATPase

    UniProtKB/Swiss-Prot: AT11B_HUMAN, Q9Y2G3
    Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily


    Find genes that share domains with ATP11B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AT11B_HUMAN, Q9Y2G3
    Catalytic activity: ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2)

         Enzyme Numbers (IUBMB): EC 3.6.3.11 2 EC 3.6.32

         Gene Ontology (GO): Selected molecular function terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0000287magnesium ion binding IEA--
    GO:0004012phospholipid-translocating ATPase activity TAS11015572
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IEA--
         
    Find genes that share ontologies with ATP11B           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for ATP11B:
     Increased gamma-H2AX phosphory  Synthetic lethal with c-Myc af 

         1 MGI phenotypic allele for Atp11b (no phenotypes)

    Find genes that share phenotypes with ATP11B           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ATP11B

    miRNA
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    miRTarBase miRNAs that target ATP11B:
    hsa-mir-652-3p (MIRT039507), hsa-mir-21-5p (MIRT030997), hsa-mir-222-3p (MIRT046578)

    Block miRNA regulation of human, mouse, rat ATP11B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ATP11B (see all 42):
    hsa-miR-323-3p hsa-miR-4291 hsa-miR-429 hsa-miR-128 hsa-miR-3921 hsa-miR-183* hsa-miR-9 hsa-miR-29a*
    SwitchGear 3'UTR luciferase reporter plasmidATP11B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ATP11B

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    AT11B_HUMAN, Q9Y2G3: Recycling endosome membrane; Multi-pass membrane protein. Early endosome. Endoplasmic
    reticulum. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the
    presence of TMEM30A, mainly located in recycling endosomes
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    endosome5
    nucleus5
    plasma membrane4

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005637nuclear inner membrane NAS11790799
    GO:0005769early endosome IEA--
    GO:0005783endoplasmic reticulum IDA--
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with ATP11B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ATP11B About    
    See pathways by source

    SuperPathContained pathways About
    1Ion channel transport
    Ion channel transport0.58
    2Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Transmembrane transport of small molecules0.47
    3Ion transport by P-type ATPases
    Ion transport by P-type ATPases


    Find genes that share SuperPaths with ATP11B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ATP11B
        Ion transport by P-type ATPases


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ATP11B
    Interactions:

        Search GeneGlobe Interaction Network for ATP11B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for ATP11B (ENSP000003211954) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TMEM30AENSP000003590674STRING: ENSP00000359067
    TMEM30BENSP000003479304STRING: ENSP00000347930
    MON2ENSP000003772524STRING: ENSP00000377252
    ARFGEF1ENSP000002622154STRING: ENSP00000262215
    GBF1ENSP000003590004STRING: ENSP00000359000
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport NAS11790799
    GO:0006812cation transport ----
    GO:0015914phospholipid transport ----
    GO:0015917aminophospholipid transport TAS11015572
    GO:0034220ion transmembrane transport TAS--

    Find genes that share ontologies with ATP11B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ATP11B (AT11B)

    Selected HMDB Compounds for ATP11B (see all 2605)    About this table
    CompoundSynonyms CAS #PubMed Ids
    PC(O-16:0/18:2(9Z,12Z))1-hexadecyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine (see all 5)88542-95-412486725
    PE(O-16:1(1Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 15)--12486725
    PE(O-18:1(1Z)/20:4(5Z,8Z,11Z,14Z))1-alkenyl-2-acyl-glycerophosphoethanolamine (see all 19)103597-60-012486725
    PE(P-16:0e/0:0)2-azaniumylethyl [(2R)-3-[(E)-hexadec-1-enoxy]-2-hydroxy-propyl] phosphate;1-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine ;LysoPE(dm16:0e) --12486725
    PE(P-16:0e/18:1(9Z))2-(9Z-octadecanoyl)-1-hexadecyl-sn-glycero-3-phosphoethanolamine --12486725
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    PA(16:0/16:0)Dipalmitoylphosphatidic acid (see all 25)7091-44-3--
    PA(16:0/18:1(11Z))PA(16:0/18:1n7) (see all 10)----
    PA(16:0/18:1(9Z))PA(16:0/18:1n9) (see all 10)----



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ATP11B gene: 
    NM_014616.2  

    Unigene Cluster for ATP11B:

    ATPase, class VI, type 11B
    Hs.478429  [show with all ESTs]
    Unigene Representative Sequence: NM_014616
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000323116(uc003flb.3 uc010hxg.3) ENST00000493826(uc003fla.3)
    ENST00000482794 ENST00000498086 ENST00000490303(uc003flc.3 uc011bqm.1 uc010hxf.1)
    ENST00000466758 ENST00000482070 ENST00000491699 ENST00000484691 ENST00000475636(uc010hxh.1)

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    hsa-miR-323-3p hsa-miR-4291 hsa-miR-429 hsa-miR-128 hsa-miR-3921 hsa-miR-183* hsa-miR-9 hsa-miR-29a*
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    Additional mRNA sequence: 

    AB023173.1 AF156548.1 AK093727.1 AK296750.1 AK304855.1 AL133061.1 BC010630.1 BC033880.2 
    BC042180.1 BX537779.1 DQ925668.1 

    7 DOTS entries:

    DT.313940  DT.92439111  DT.101976543  DT.100791782  DT.95207644  DT.101978386  DT.40200574 

    Selected AceView cDNA sequences (see all 211):

    AI738517 AA825535 BC010630 BI962815 AA232249 CB132533 BE773502 BX099431 
    BM827900 AL133061 AA993750 AA969873 AB023173 H83121 CD106757 BF515408 
    BM760513 AK093727 BM820729 BE773475 BQ010323 AI090097 AA706956 BI963906 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ATP11B    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15 ^ 16a · 16b · 16c ^ 17
    SP1:                                                                                                                              
    SP2:                                                                                                                              
    SP3:                                                                                                  -                           
    SP4:                                                                                                                              
    SP5:                                                                                                  -           -     -         


    ECgene alternative splicing isoforms for ATP11B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ATP11B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACATCGTTGT
    ATP11B Expression
    About this image

    ATP11B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ATP11B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.478429
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATP11B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ATP11B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atp11b1 , 5 ATPase, class VI, type 11B1, 5 90.7(n)1
    93.53(a)1
      3 (17.36 cM)5
    762951  NM_029570.31  NP_083846.21 
     357541345 
    chicken
    (Gallus gallus)
    Aves ATP11B1 ATPase, class VI, type 11B 80.92(n)
    85.78(a)
      424964  XM_422773.4  XP_422773.4 
    lizard
    (Anolis carolinensis)
    Reptilia ATP11B6
    ATPase, class VI, type 11B
    69(a)
    1 ↔ 1
    3(238573-328604)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia atp11b1 ATPase, class VI, type 11B 76.61(n)
    81.87(a)
      100135380  XM_004914415.1  XP_004914472.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-211e20.101 si:dkey-211e20.10 71.21(n)
    80(a)
      100329583  XM_005170552.1  XP_005170609.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG43011 , 3 calcium-transporting ATPase3
    CG43011
    42(a)3
    47.48(n)1
    44.51(a)1
      14C43
    326101  NM_001258782.11  NP_001245711.11 


    ENSEMBL Gene Tree for ATP11B (if available)
    TreeFam Gene Tree for ATP11B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ATP11B gene
    ATP11A2  ATP8B12  ATP8A12  ATP11C2  ATP8B42  ATP8A22  ATP8B22  ATP8B32  
    12 SIMAP similar genes for ATP11B using alignment to 9 protein entries:     AT11B_HUMAN (see all proteins):
    DKFZp779H1459    ATP11A    DKFZp434P0831    ATP11C    ATP8A1    ATP8B4
    ATP9B    ATP8A2    ATP8B2    ATP8B1    ATP8B3    ATP9A

    Find genes that share paralogs with ATP11B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ATP11B (see all 2460)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1872521591,2
    --182365373(+) GCACAC/TACACA 1 -- int10--------
    rs1920032151,2
    --182365384(+) CATTGA/CCAACA 1 -- int10--------
    rs1432228601,2
    --182365922(+) GAATAC/GGAAAG 1 -- int10--------
    rs76395751,2
    C,F--182365940(+) TATGAT/CTTTAT 1 -- int15Minor allele frequency- C:0.15NA CSA WA EA 361
    rs1466950941,2
    --182366036(+) TTTACC/GTCACC 1 -- int10--------
    rs1403119551,2
    --182366046(+) CAGAAG/TAGCAA 1 -- int10--------
    rs1143442191,2
    C,F--182366080(+) TGACTG/CAATCA 1 -- int11Minor allele frequency- C:0.03WA 118
    rs1499277181,2
    C--182366086(+) AATCAA/GTATCG 1 -- int10--------
    rs1165274471,2
    C,F--182366091(+) GTATCG/ATATAG 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1450173641,2
    C--182366183(+) TATCAC/TTGATG 1 -- int10--------

    HapMap Linkage Disequilibrium report for ATP11B (182511288 - 182639423 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ATP11B: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ATP11B
    DNA2.0 Custom Variant and Variant Library Synthesis for ATP11B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605869    OMIM disorders: --


    Find genes that share disorders with ATP11B           About GenesLikeMe


    Export disorders for ATP11B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ATP11B gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with ATP11B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1999)
    2. Differential expression of putative transbilayer amphipath transporters. (PubMed id 11015572)1, 2, 3 Halleck M.S.... Schlegel R.A. (Physiol. Genomics 1999)
    3. ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner. (PubMed id 21914794)1, 2 Takatsu H.... Shin H.W. (J. Biol. Chem. 2011)
    4. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)1, 2 Muzny D.M....Gibbs R.A. (Nature 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Reanalysis of ATP11B, a Type IV P-type ATPase. (PubMed id 11790799)1, 2 Halleck M.S.... Williamson P.L. (J. Biol. Chem. 2002)
    7. ATP11B mediates platinum resistance in ovarian cancer. (PubMed id 23585472)1 Moreno-Smith M....Sood A.K. (J. Clin. Invest. 2013)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23200 HGNC: 13553 AceView: ATP11B Ensembl:ENSG00000058063 euGenes: HUgn23200
    ECgene: ATP11B H-InvDB: ATP11B

    (According to HUGE)
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    HUGE: KIAA0956

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ATP11B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ATP11B gene:
    Search GeneIP for patents involving ATP11B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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