Aliases for ATOX1 Gene
External Ids for ATOX1 Gene
Previous GeneCards Identifiers for ATOX1 Gene
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]
GeneCards Summary for ATOX1 Gene
ATOX1 (Antioxidant 1 Copper Chaperone) is a Protein Coding gene. Among its related pathways are Cellular Senescence and Mineral absorption. GO annotations related to this gene include copper ion binding and copper chaperone activity.
UniProtKB/Swiss-Prot for ATOX1 Gene
Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense