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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATOH8 Gene

protein-coding   GIFtS: 48
GCID: GC02P085978

Atonal Homolog 8 (Drosophila)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Atonal Homolog 8 (Drosophila)1 2     Atonal Homolog 62
Basic Helix Loop Helix Transcription Factor 61 2     Basic Helix-Loop-Helix Transcription Factor 62
Class A Basic Helix-Loop-Helix Protein 212 3     Protein Atonal Homolog 82
Helix-Loop-Helix Protein HATH-62 3     ATH63
bHLHa212 3     BHLHA213
HATH62     hATH63

External Ids:    HGNC: 241261   Entrez Gene: 849132   Ensembl: ENSG000001688747   UniProtKB: Q96SQ73   
ORGUL members:         
NONCODE14:n338895      

Export aliases for ATOH8 gene to outside databases

Previous GC identifers: GC00U913743 GC02P085956 GC02P085892


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ATOH8 Gene: 
ATOH8 (atonal homolog 8 (Drosophila)) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with ATOH8 include endotheliitis, and neuronitis. GO annotations related to this gene include protein dimerization activity and DNA binding.

UniProtKB/Swiss-Prot: ATOH8_HUMAN, Q96SQ7
Function: Putative transcription factor. May be implicated in specification and differentiation of neuronal cell
lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022184.15  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATOH8 gene promoter:
         STAT5B   STAT1   STAT4   STAT1beta   STAT5A   STAT1alpha   N-Myc   AREB6   STAT2   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATOH8 promoter sequence
   Search SABiosciences Chromatin IP Primers for ATOH8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATOH8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p11.2   Ensembl cytogenetic band:  2p11.2   HGNC cytogenetic band: 2p11.2

ATOH8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATOH8 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P085978:  view genomic region     (about GC identifiers)

Start:
85,978,467 bp from pter      End:
86,018,506 bp from pter
Size:
40,040 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ATOH8_HUMAN, Q96SQ7 (See protein sequence)
Recommended Name: Protein atonal homolog 8  
Size: 321 amino acids; 34644 Da
Subunit: Efficient DNA binding requires dimerization with another bHLH protein (By similarity)
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q504S2 Q659B0
Alternative splicing: 2 isoforms:  Q96SQ7-1   Q96SQ7-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ATOH8: NX_Q96SQ7

Explore proteomics data for ATOH8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96SQ7

  • ATOH8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ATOH8 Protein Expression
    REFSEQ proteins: NP_116216.2  
    ENSEMBL proteins: 
     ENSP00000304676  

    Human Recombinant Protein Products for ATOH8: 
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    OriGene Protein Over-expression Lysate for ATOH8
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    OriGene Custom Protein Services for ATOH8
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    Novus Biologicals ATOH8 Proteins
    Novus Biologicals ATOH8 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    ATOH8 for ontologies           About GeneDecksing



    ATOH8 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    bHLH: Basic helix-loop-helix proteins

    1 InterPro protein domain:
     IPR011598 bHLH_dom

    Graphical View of Domain Structure for InterPro Entry Q96SQ7

    ProtoNet protein and cluster: Q96SQ7

    1 Blocks protein domain: IPB001092 Basic helix-loop-helix dimerization domain bHLH

    UniProtKB/Swiss-Prot: ATOH8_HUMAN, Q96SQ7
    Similarity: Contains 1 bHLH (basic helix-loop-helix) domain


    ATOH8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ATOH8_HUMAN, Q96SQ7
    Function: Putative transcription factor. May be implicated in specification and differentiation of neuronal cell
    lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation (By
    similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0046983protein dimerization activity IEA--
         
    ATOH8 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for ATOH8:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Atoh8):
     mortality/aging 

    ATOH8 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ATOH8 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ATOH8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ATOH8 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ATOH8 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ATOH8
    8/52 QIAGEN miScript miRNA Assays for microRNAs that regulate ATOH8 (see all 52):
    hsa-miR-193a-3p hsa-miR-1321 hsa-miR-106a hsa-miR-650 hsa-miR-183* hsa-miR-9 hsa-miR-1184 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidATOH8 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATOH8

    Gene Editing
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    Clone
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                         Customized lentivirus expression plasmids for stable overexpression of ATOH8 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATOH8


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATOH8

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for ATOH8 (ENSP000003046764) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TCF3ENSP000002629654STRING: ENSP00000262965
    CCNB1IP1ENSP000003373964STRING: ENSP00000337396
    CYP3A5ENSP000002229824STRING: ENSP00000222982
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0007399nervous system development IEA--
    GO:0030154cell differentiation IEA--

    ATOH8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ATOH8

    Search CenterWatch for drugs/clinical trials and news about ATOH8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ATOH8 gene: 
    NM_032827.6  

    Unigene Cluster for ATOH8:

    Atonal homolog 8 (Drosophila)
    Hs.135569  [show with all ESTs]
    Unigene Representative Sequence: NM_032827
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000469442 ENST00000306279(uc002sqn.3) ENST00000463422(uc002sqm.4)
    ENST00000473116 ENST00000489682
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ATOH8
    8/52 QIAGEN miScript miRNA Assays for microRNAs that regulate ATOH8 (see all 52):
    hsa-miR-193a-3p hsa-miR-1321 hsa-miR-106a hsa-miR-650 hsa-miR-183* hsa-miR-9 hsa-miR-1184 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidATOH8 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Clone
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    GenScript: all cDNA clones in your preferred vector: ATOH8 (NM_032827)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ATOH8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATOH8
    Sirion Biotech Customized lentivirus for stable overexpression of ATOH8 
                         Customized lentivirus expression plasmids for stable overexpression of ATOH8 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATOH8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATOH8

    Additional mRNA sequence: 

    AF529205.1 AK027614.1 AK074681.1 AK093766.1 AK096049.1 AL831857.1 BC019854.1 BC021207.2 
    BC094832.1 CR749611.1 

    8 DOTS entries:

    DT.437368  DT.97801441  DT.100754792  DT.40228703  DT.97828799  DT.95365510  DT.403349  DT.95365508 

    24/84 AceView cDNA sequences (see all 84):

    AI361517 BX115320 AK074681 BG820302 BM770138 BM709971 AL831857 BM756548 
    CD516709 BE393045 CA396816 BF725177 BM756547 AK027614 BQ067527 CR625589 
    CD672386 BG057085 CF132508 BE393035 BQ015357 CA390309 AL701399 BF434995 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ATOH8 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c · 8d
    SP1:                                -                                                   
    SP2:              -     -           -     -     -     -     -                           
    SP3:        -     -     -           -     -     -     -     -                           
    SP4:                                -     -     -     -     -                           
    SP5:                                      -     -     -     -                           


    ECgene alternative splicing isoforms for ATOH8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATOH8 expression in normal human tissues (normalized intensities)      ATOH8 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACAGAAAAA
    ATOH8 Expression
    About this image


    ATOH8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 4 entries
             HyStem+BMP4-induced E15 cells
             Human Vertebral Mesenchymal Stem Cells (HVMSC)   
             mandibular prominence tissue e10.0   
     
     Adipose (Muscoskeletal System)    fully expand to see all 4 entries
             HyStem+BMP4-induced E15 cells
             Human Preadipocyte-subcutaneous (HPA-s)   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+BMP4-induced E15 cells
     
     Head Mesenchyme (Muscoskeletal System)
             mandibular prominence tissue e10.0   
     
     Mesenchymal Stem Cells
             Human Vertebral Mesenchymal Stem Cells (HVMSC)   

    See ATOH8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATOH8

    SOURCE GeneReport for Unigene cluster: Hs.135569

    UniProtKB/Swiss-Prot: ATOH8_HUMAN, Q96SQ7
    Tissue specificity: Expressed in lung, liver, kidney, heart and pancreas. Expressed in endothel of umbilical
    vessels

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATOH8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ATOH8 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atoh81 , 5 atonal homolog 8 (Drosophila)1, 5 87.66(n)1
    90.19(a)1
      6 (32.27 cM)5
    710931  NM_153778.31  NP_722473.11 
     722061775 
    chicken
    (Gallus gallus)
    Aves ATOH81 atonal homolog 8 (Drosophila) 68.05(n)
    70.97(a)
      771738  NM_001177739.1  NP_001171210.1 
    lizard
    (Anolis carolinensis)
    Reptilia ATOH86
    Uncharacterized protein
    87(a)
    1 ↔ 1
    GL343395.1(872168-899883)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.221502 Transcribed sequence with weak similarity to protein more 80.12(n)    CK139056.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta net6
    net
    24(a)
    1 ↔ 1
    2L(82421-87387)


    ENSEMBL Gene Tree for ATOH8 (if available)
    TreeFam Gene Tree for ATOH8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/815 SNPs in ATOH8 are shown (see all 815)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1428345061,2
    --85978982(+) GAGGCA/TATGGT 1 -- us2k10--------
    rs760420161,2
    F--85979002(+) AGGTTC/TGCGGG 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1510092791,2
    C--85979012(+) GAGGAA/GGGGGA 1 -- us2k10--------
    rs75678521,2
    C,F,H--85979027(+) AGCTGG/TTCATC 1 -- us2k112Minor allele frequency- T:0.16WA NA CSA EA 378
    rs1871948201,2
    --85979028(+) GCTGTG/TCATCG 1 -- us2k10--------
    rs1396427751,2
    --85979036(+) TCGAAC/GGGTGA 1 -- us2k10--------
    rs1497145051,2
    --85979059(+) GTTGCA/CAAGGG 1 -- us2k10--------
    rs1908786781,2
    --85979134(+) CAGGAC/GAATGA 1 -- us2k10--------
    rs1467151441,2
    --85979151(+) CTCTTC/TGGCAG 1 -- us2k10--------
    rs1403515761,2
    --85979292(+) ACTATA/GTTCAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ATOH8 (85978467 - 86018506 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ATOH8:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv4204n71CNV Loss21882294
    nsv874468CNV Loss21882294
    nsv829487CNV Gain20364138

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ATOH8
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for ATOH8:    About MalaCards
    endotheliitis    neuronitis


    ATOH8 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ATOH8
    Human Genome Epidemiology (HuGE) Navigator: ATOH8 (3 documents)

    Export disorders for ATOH8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATOH8 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with ATOH8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Gene expression profile of human endothelial cells exposed to sustained fluid shear stress. (PubMed id 12419857)1, 2, 3 Wasserman S.M.... Topper J.N. (2002)
    2. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Biochemical and phosphoproteomic analysis of the helix -loop-helix protein E47. (PubMed id 22354994)1 Teachenor R....Murre C. (2012)
    5. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    6. Diversification and molecular evolution of ATOH8, a g ene encoding a bHLH transcription factor. (PubMed id 21857980)1 Chen J....Brand-Saberi B. (2011)
    7. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84913 HGNC: 24126 AceView: ATOH8 Ensembl:ENSG00000168874 euGenes: HUgn84913
    ECgene: ATOH8 H-InvDB: ATOH8

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATOH8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ATOH8 gene:
    Search GeneIP for patents involving ATOH8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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