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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATOH7 Gene

protein-coding   GIFtS: 51
GCID: GC10M069990

Atonal Homolog 7 (Drosophila)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Atonal Homolog 7 (Drosophila)1 2     Protein Atonal Homolog 72
Class A Basic Helix-Loop-Helix Protein 132 3     ATH53
Helix-Loop-Helix Protein HATH-52 3     BHLHA133
bHLHa132 3     hATH53
Math52     

External Ids:    HGNC: 139071   Entrez Gene: 2202022   Ensembl: ENSG000001797747   OMIM: 6098755   UniProtKB: Q8N1003   

Export aliases for ATOH7 gene to outside databases

Previous GC identifers: GC10M068802 GC10M069077 GC10M069882 GC10M069335 GC10M069334 GC10M069660 GC10M063990


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ATOH7 Gene:
This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with
similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this
gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are
associated with nonsyndromic congenital retinal nonattachment. (provided by RefSeq, Dec 2011)

GeneCards Summary for ATOH7 Gene: 
ATOH7 (atonal homolog 7 (Drosophila)) is a protein-coding gene. Diseases associated with ATOH7 include congenital blindness due to retinal nonattachment, and retinitis. GO annotations related to this gene include protein dimerization activity and DNA binding. An important paralog of this gene is NEUROG3.

UniProtKB/Swiss-Prot: ATOH7_HUMAN, Q8N100
Function: Transcription factor involved in the differentiation of retinal ganglion cells (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.2  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATOH7 gene promoter:
         USF1   RP58   NF-E2 p45   Tal-1beta   SRY   HOXA5   ITF-2   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATOH7 promoter sequence
   Search SABiosciences Chromatin IP Primers for ATOH7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATOH7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q21.3|10q21.3-q22.1   Ensembl cytogenetic band:  10q21.3   HGNC cytogenetic band: 10q22.2

ATOH7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATOH7 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M069990:  view genomic region     (about GC identifiers)

Start:
69,990,381 bp from pter      End:
69,991,871 bp from pter
Size:
1,491 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ATOH7_HUMAN, Q8N100 (See protein sequence)
Recommended Name: Protein atonal homolog 7  
Size: 152 amino acids; 16871 Da
Subcellular location: Nucleus (Probable)

Explore the universe of human proteins at neXtProt for ATOH7: NX_Q8N100

Explore proteomics data for ATOH7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N100

  • ATOH7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ATOH7 Protein Expression
    REFSEQ proteins: NP_660161.1  
    ENSEMBL proteins: 
     ENSP00000362777  

    Human Recombinant Protein Products for ATOH7: 
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    Novus Biologicals ATOH7 Lysate
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ATOH7 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    ATOH7 for ontologies           About GeneDecksing



    ATOH7 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of ATOH7
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    Assay Products for ATOH7: 
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    Cloud-Clone Corp. ELISAs for ATOH7 
    Cloud-Clone Corp. CLIAs for ATOH7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    bHLH: Basic helix-loop-helix proteins

    1 InterPro protein domain:
     IPR011598 bHLH_dom

    Graphical View of Domain Structure for InterPro Entry Q8N100

    ProtoNet protein and cluster: Q8N100

    1 Blocks protein domain: IPB001092 Basic helix-loop-helix dimerization domain bHLH

    UniProtKB/Swiss-Prot: ATOH7_HUMAN, Q8N100
    Similarity: Contains 1 bHLH (basic helix-loop-helix) domain


    ATOH7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ATOH7_HUMAN, Q8N100
    Function: Transcription factor involved in the differentiation of retinal ganglion cells (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0046983protein dimerization activity IEA--
         
    ATOH7 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ATOH7:
     Increased gamma-H2AX phosphory 

         7 MGI mutant phenotypes (inferred from 7 alleles(MGI details for Atoh7):
     behavior/neurological  cardiovascular system  cellular  nervous system  normal 
     reproductive system  vision/eye 

    ATOH7 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ATOH7 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ATOH7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ATOH7 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ATOH7 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ATOH7
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ATOH7:
    hsa-miR-3658 hsa-miR-1283 hsa-miR-561 hsa-miR-3921 hsa-miR-1224-5p
    SwitchGear 3'UTR luciferase reporter plasmidATOH7 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for ATOH7
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATOH7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ATOH7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Transcription factors in neurogenesis
    Transcription factors in neurogenesis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for ATOH7
        Transcription factors in neurogenesis




    ATOH7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATOH7

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0007399nervous system development IEA--
    GO:0007623circadian rhythm IEA--
    GO:0009649entrainment of circadian clock IEA--

    ATOH7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ATOH7

    Search CenterWatch for drugs/clinical trials and news about ATOH7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ATOH7 gene: 
    NM_145178.3  

    Unigene Cluster for ATOH7:

    Atonal homolog 7 (Drosophila)
    Hs.737072  [show with all ESTs]
    Unigene Representative Sequence: NM_145178
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000373673(uc001jnq.3)
    miRNA
    Products:
         
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ATOH7:
    hsa-miR-3658 hsa-miR-1283 hsa-miR-561 hsa-miR-3921 hsa-miR-1224-5p
    SwitchGear 3'UTR luciferase reporter plasmidATOH7 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATOH7
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ATOH7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATOH7
    Sirion Biotech Customized lentivirus for stable overexpression of ATOH7 
                         Customized lentivirus expression plasmids for stable overexpression of ATOH7 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ATOH7
    OriGene qSTAR qPCR primer pairs in human, mouse for ATOH7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATOH7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATOH7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATOH7

    Additional mRNA sequence: 

    AB593108.1 AB593109.1 BC032621.1 

    1 DOTS entry:

    DT.97784371 

    7 AceView cDNA sequences:

    BK000277 NM_145178 AI799665 BM474709 BC032621 H05728 BU151599 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATOH7 expression in normal human tissues (normalized intensities)      ATOH7 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTATCGGTG
    ATOH7 Expression
    About this image


    ATOH7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Eye (Sensory Organs)    fully expand to see all 5 entries
             Ganglion Precursor Cells Ganglion Cell Layer
             Retina
             lens   
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebellum
             brain/hindbrain   
     
     Neural Tube (Nervous System)
             Metencephalon

     -- (Nervous System)
             mouse/organ system/nervous system/central nervous system   

    See ATOH7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATOH7

    SOURCE GeneReport for Unigene cluster: Hs.737072
        SABiosciences Custom PCR Arrays for ATOH7
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATOH7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATOH7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ATOH7 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atoh71 , 5 atonal homolog 7 (Drosophila)1, 5 84.13(n)1
    85.71(a)1
      10 (32.54 cM)5
    534041  NM_016864.11  NP_058560.11 
     631001565 
    chicken
    (Gallus gallus)
    Aves ATOH71 atonal homolog 7 (Drosophila) 62.44(n)
    64(a)
      395388  NM_204668.1  NP_989999.1 
    lizard
    (Anolis carolinensis)
    Reptilia ATOH76
    Uncharacterized protein
    64(a)
    1 ↔ 1
    GL343215.1(1447009-1447458)
    African clawed frog
    (Xenopus laevis)
    Amphibia atoh5b-A2 atonal homolog 5b 74.68(n)    U93171.1 
    zebrafish
    (Danio rerio)
    Actinopterygii atoh72 atonal homolog 7 82.39(n)   58216  AB049457.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta amos6
    absent MD neurons and olfactory sensilla
    21(a)
    1 → many
    2L(18596047-18597200)
    worm
    (Caenorhabditis elegans)
    Secernentea lin-326
    Protein lin-32
    28(a)
    1 → many
    X(2229124-2230102)


    ENSEMBL Gene Tree for ATOH7 (if available)
    TreeFam Gene Tree for ATOH7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ATOH7 gene
    NEUROG32  NEUROD22  NEUROG22  NEUROD12  NEUROD62  ATOH12  BHLHA152  NEUROG12  
    NEUROD42  
    6 SIMAP similar genes for ATOH7 using alignment to 2 protein entries:     ATOH7_HUMAN (see all proteins):
    ATOH1    TAL2    NEUROD2    NEUROD6    NEUROD4    TCF15

    ATOH7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/60 SNPs in ATOH7 are shown (see all 60)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1876104941,2
    --70365599(+) TTGCTC/TCCATT 1 -- ds50010--------
    rs1146923161,2
    C,F--70365696(+) TTCTGT/GGTTAG 1 -- ds50011Minor allele frequency- G:0.08WA 118
    rs1909507901,2
    --70365915(+) AAGTTA/GACAGA 1 -- ds50010--------
    rs1499016681,2
    --70365961(+) GCTTTC/TTGAGG 1 -- ds50010--------
    rs732691661,2
    C,F--70365969(+) AGGAAC/GTACTA 1 -- ds50012Minor allele frequency- G:0.06WA 120
    rs1449263601,2
    C--70366002(+) GGTCGA/GATTAG 1 -- ds50010--------
    rs1827834401,2
    C--70366250(+) ACACAA/CTGCAC 1 -- ut310--------
    rs732691671,2
    C,F--70366432(+) TCCCTC/GAAAGT 1 -- ut312Minor allele frequency- G:0.07WA 120
    rs2019555261,2
    C--70366846(+) TCACAG/ATGGAG 2 /H syn11Minor allele frequency- A:0.00EU 889
    rs2001561081,2
    --70366948(+) TCGTAC/GTTGGA 2 N K mis10--------

    HapMap Linkage Disequilibrium report for ATOH7 (69990381 - 69991871 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ATOH7:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv526735CNV Loss19592680


    Human Gene Mutation Database (HGMD): ATOH7
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ATOH7
    DNA2.0 Custom Variant and Variant Library Synthesis for ATOH7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609875    OMIM disorders: --

    UniProtKB/Swiss-Prot: ATOH7_HUMAN, Q8N100
  • Retinal non-attachment, congenital, non-syndromic (RNANC) [MIM:221900]: A condition characterized by
    separation of the inner layers of the retina (neural retina) from the pigment epithelium. Clinical findings
    include lack of perception of light, massive retrolental mass, shallow anterior chamber, and nystagmus in
    otherwise normal individuals. Note=The disease is caused by mutations affecting the gene represented in this
    entry. RNANC is caused by a 6.5 kb deletion that spans a remote cis regulatory element 20 kb upstream from ATOH7

  • 6 diseases for ATOH7:    About MalaCards
    congenital blindness due to retinal nonattachment    retinitis    primary open angle glaucoma    open-angle glaucoma
    glaucoma    neuronitis

    1 disease from the University of Copenhagen DISEASES database for ATOH7:
    Glaucoma

    ATOH7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ATOH7
    Human Genome Epidemiology (HuGE) Navigator: ATOH7 (4 documents)

    Export disorders for ATOH7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATOH7 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with ATOH7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterization and mapping of ATOH7, a human atonal homolog with a predicted role in retinal ganglion cell development. (PubMed id 11889557)1, 2, 3, 9 Brown N.L.... Glaser T. (2002)
    2. Deletion of a remote enhancer near ATOH7 disrupts ret inal neurogenesis, causing NCRNA disease. (PubMed id 21441919)1, 2 Ghiasvand N.M....Glaser T. (2011)
    3. Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. (PubMed id 21307088)1, 4 Khor C.C....Aung T. (2011)
    4. A genome-wide association study of optic disc paramet ers. (PubMed id 20548946)1, 4 Ramdas W.D....van Duijn C.M. (2010)
    5. Genome-wide association identifies ATOH7 as a major g ene determining human optic disc size. (PubMed id 20395239)1, 4 Macgregor S....Mackey D.A. (2010)
    6. Exhaustive identification of human class II basic helix-loop-helix proteins by virtual library screening. (PubMed id 14516699)1, 2 McLellan A.S.... Kealey T. (2002)
    7. Genetic variants associated with disordered eating. (PubMed id 23568457)1 Wade T.D....Martin N.G. (2013)
    8. Next generation sequencing identifies mutations in Ato nal homolog 7 (ATOH7) in families with global eye developmental defects. (PubMed id 22068589)1 Khan K....Ali M. (2012)
    9. Interactive effects of ATOH7 and RFTN1 in association with adult-onset primary open-angle glaucoma. (PubMed id 22222511)1 Chen J.H....Zhang M. (2012)
    10. ATOH7 mutations cause autosomal recessive persistent h yperplasia of the primary vitreous. (PubMed id 22645276)1 Prasov L....Glaser T. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 220202 HGNC: 13907 AceView: ATOH7 Ensembl:ENSG00000179774 euGenes: HUgn220202
    ECgene: ATOH7 H-InvDB: ATOH7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATOH7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ATOH7 gene:
    Search GeneIP for patents involving ATOH7

    GeneCards and IP:
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