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ATOH1 Gene

protein-coding   GIFtS: 56
GCID: GC04P094750

Atonal Homolog 1 (Drosophila)

  See ATOH1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Atonal Homolog 1 (Drosophila)1 2     HATH12
ATH12 3 5     MATH-12
Class A Basic Helix-Loop-Helix Protein 142 3     Protein Atonal Homolog 12
Helix-Loop-Helix Protein HATH-12 3     BHLHA143
bHLHa142 3     hATH13

External Ids:    HGNC: 7971   Entrez Gene: 4742   Ensembl: ENSG000001722387   OMIM: 6014615   UniProtKB: Q928583   

Export aliases for ATOH1 gene to outside databases

Previous GC identifers: GC04P094907 GC04P095051 GC04P095208 GC04P095107 GC04P090487


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ATOH1 Gene:
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box
dependent transcription along with E47. (provided by RefSeq, Jul 2008)

GeneCards Summary for ATOH1 Gene:
ATOH1 (atonal homolog 1 (Drosophila)) is a protein-coding gene. Diseases associated with ATOH1 include goblet cell carcinoid, and cerebellar liponeurocytoma. GO annotations related to this gene include protein dimerization activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is NEUROG3.

UniProtKB/Swiss-Prot: ATOH1_HUMAN, Q92858
Function: Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but
the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the
differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity)

Gene Wiki entry for ATOH1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NC_018915.2  NT_016354.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the ATOH1 gene promoter:
         SRF   p53   NCX/Ncx   SRF (504 AA)   FOXO3   Nkx2-5   FOXO3b   SRY   STAT3   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATOH1 promoter sequence
   Search Chromatin IP Primers for ATOH1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ATOH1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q22   Ensembl cytogenetic band:  4q22.2   HGNC cytogenetic band: 4q22

ATOH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATOH1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P094750:  view genomic region     (about GC identifiers)

Start:
94,750,042 bp from pter      End:
94,751,221 bp from pter
Size:
1,180 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ATOH1_HUMAN, Q92858 (See protein sequence)
Recommended Name: Protein atonal homolog 1  
Size: 354 amino acids; 38160 Da
Subunit: Efficient DNA binding requires dimerization with another bHLH protein
Secondary accessions: Q14CT9

Explore the universe of human proteins at neXtProt for ATOH1: NX_Q92858

Explore proteomics data for ATOH1 at MOPED


See ATOH1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_005163.1  
ENSEMBL proteins: 
 ENSP00000302216  

ATOH1 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
bHLH: Basic helix-loop-helix proteins

1 InterPro protein domain:
 IPR011598 bHLH_dom

Graphical View of Domain Structure for InterPro Entry Q92858

ProtoNet protein and cluster: Q92858

1 Blocks protein domain: IPB001092 Basic helix-loop-helix dimerization domain bHLH

UniProtKB/Swiss-Prot: ATOH1_HUMAN, Q92858
Similarity: Contains 1 bHLH (basic helix-loop-helix) domain


Find genes that share domains with ATOH1           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: ATOH1_HUMAN, Q92858
Function: Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but
the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the
differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity)

     Genatlas biochemistry entry for ATOH1:
Drosophila atonal proneural gene homolog,involved in the development of nervous system

     Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding ----
GO:0003700sequence-specific DNA binding transcription factor activity TAS8872459
GO:0005515protein binding ----
GO:0031490chromatin DNA binding IEA--
GO:0043565sequence-specific DNA binding IEA--
     
Find genes that share ontologies with ATOH1           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for ATOH1:
 Synthetic lethal with Ras 

     10 MGI mutant phenotypes (inferred from 9 alleles(MGI details for Atoh1):
 cellular  digestive/alimentary  endocrine/exocrine gland  hearing/vestibular/ear  homeostasis/metabolism 
 mortality/aging  nervous system  no phenotypic analysis  normal  respiratory system 

Find genes that share phenotypes with ATOH1           About GenesLikeMe

Animal Models:
     MGI mouse knock-outs for ATOH1: Atoh1tm1Hzo Atoh1tm3.1Hzo

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ATOH1
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ATOH1
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ATOH1

Transcription Factor Targeting: 
Targeting motifs: HOMER Transcription Factor Regulatory Elements motif viewer 
                                      Consensus sequence:  VNAVCAGCTGGC 

miRNA
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
ATOH1_HUMAN, Q92858: Nucleus (Probable)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus4
cytosol2

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus ISS--

Find genes that share ontologies with ATOH1           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for ATOH1 About    
See pathways by source

SuperPathContained pathways About
1Transcription factors in neurogenesis
Transcription factors in neurogenesis



    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ATOH1
Interactions:

    GeneGlobe Interaction Network for ATOH1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for ATOH1 (Q928583 ENSP000003022164) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
InteractantInteraction Details
GeneCardExternal ID(s)
HMGB1P094293, ENSP000003430404I2D: score=1 STRING: ENSP00000343040
TCF3P159233, ENSP000002629654I2D: score=1 STRING: ENSP00000262965
RUNX1T1Q064553, ENSP000002658144I2D: score=1 STRING: ENSP00000265814
MSX1ENSP000003721704STRING: ENSP00000372170
TCF12ENSP000003310574STRING: ENSP00000331057
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Gene Ontology (GO): Selected biological process terms (see all 20):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001764neuron migration IEA--
GO:0006366transcription from RNA polymerase II promoter TAS8872459
GO:0006915apoptotic process ----
GO:0007411axon guidance IEA--
GO:0007417central nervous system development TAS8872459

Find genes that share ontologies with ATOH1           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ATOH1



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for ATOH1 gene: 
NM_005172.1  

Unigene Cluster for ATOH1:

Atonal homolog 1 (Drosophila)
Hs.532680
Unigene Representative Sequence: BC113623
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000306011(uc003hta.1)
miRNA
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  QuantiFast Probe-based Assays in human, mouse, rat ATOH1
Flow Cytometry
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eBioscience FlowRNA Probe Sets ( VA6-11271) for ATOH1 

Additional mRNA sequence: 

BC069145.1 BC069578.1 BC069594.1 BC069604.1 BC113623.1 BC113625.1 

1 DOTS entry:

DT.91670860 

5 AceView cDNA sequences:

BC069604 BC069578 NM_005172 BC069594 BC069145 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ATOH1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GGCTGAACCA
ATOH1 Expression
About this image


ATOH1 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 4) fully expand
 
 Brain (Nervous System)    fully expand to see all 16 entries
         Oligodendrocyte Precursor Cells dP3 Neural Domain
         Thalamus
         Olfactory Bulb   
 
 Neural Tube (Nervous System)    fully expand to see all 5 entries
         Oligodendrocyte Precursor Cells dP3 Neural Domain
         Metencephalon
 
 Colon (Gastrointestinal Tract)
 
 Spinal Cord (Nervous System)
ATOH1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ATOH1 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.532680
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In Situ
Assay Products:
 

 
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for ATOH1 gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Atoh11 , 5 atonal homolog 1 (Drosophila)1, 5 84.62(n)1
87.18(a)1
  6 (30.03 cM)5
119211  NM_007500.41  NP_031526.11 
 647291465 
chicken
(Gallus gallus)
Aves ATOH11 atonal homolog 1 (Drosophila) 61.64(n)
54.76(a)
  101750213  XM_004941130.1  XP_004941187.1 
lizard
(Anolis carolinensis)
Reptilia ATOH16
atonal homolog 1 (Drosophila)
71(a)
1 ↔ 1
5(48672536-48672870)
tropical clawed frog
(Xenopus tropicalis)
Amphibia atoh11 atonal homolog 1 (Drosophila) 65.44(n)
64.34(a)
  100488309  XM_004911085.1  XP_004911142.1 
zebrafish
(Danio rerio)
Actinopterygii AF024536.12   -- 81.72(n)   30303  AF024536.1 
fruit fly
(Drosophila melanogaster)
Insecta ato6
atonal
20(a)
1 ↔ 1
3R(4103514-4104996)


ENSEMBL Gene Tree for ATOH1 (if available)
TreeFam Gene Tree for ATOH1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for ATOH1 gene
NEUROG32  NEUROD22  NEUROG22  NEUROD12  NEUROD62  BHLHA152  ATOH72  NEUROG12  
NEUROD42  
3 SIMAP similar genes for ATOH1 using alignment to 2 protein entries:     ATOH1_HUMAN (see all proteins):
ATOH7    TAL2    FERD3L

Find genes that share paralogs with ATOH1           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ATOH1 (see all 102)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 4 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs728778691,2
C,F--94748224(+) ACGAGG/ATTGAA 1 -- us2k13Minor allele frequency- A:0.18WA CSA 122
rs569053521,2
C,F--94748277(+) ACCCTA/GTTCTG 1 -- us2k13Minor allele frequency- G:0.26WA 122
rs100152531,2
C,F,A,H--94748289(+) CATTCT/CGTATC 1 -- us2k119Minor allele frequency- C:0.27NS EA NA WA 2344
rs792310811,2
C,F--94748561(+) CAGGGG/ACGGTG 1 -- us2k11Minor allele frequency- A:0.12WA 118
rs774509921,2
F--94748562(+) AGGGGC/TGGTGC 1 -- us2k11Minor allele frequency- T:0.05WA 118
rs566799081,2
C,F--94748626(+) CCCAGG/AGCCAA 1 -- us2k12Minor allele frequency- A:0.10WA 120
rs1129609711,2
C,F--94748632(+) GCCAAT/GGAGCT 1 -- us2k12Minor allele frequency- G:0.15WA 120
rs1864053031,2
--94748686(+) AGGACA/CGGAGG 1 -- us2k10--------
rs1413097561,2
--94748751(+) ATGGGA/GCGGAG 1 -- us2k10--------
rs1421481891,2
C--94748814(+) GGCGGA/GAGGAG 1 -- us2k10--------

HapMap Linkage Disequilibrium report for ATOH1 (94750042 - 94751221 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for ATOH1:    About this table    
Variant IDTypeSubtypePubMed ID
nsv821636CNV Gain15273396

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing ATOH1
DNA2.0 Custom Variant and Variant Library Synthesis for ATOH1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 601461    OMIM disorders: --

4 diseases for ATOH1:    
About MalaCards
goblet cell carcinoid    cerebellar liponeurocytoma    merkel cell carcinoma    colon cancer

3 diseases from the University of Copenhagen DISEASES database for ATOH1:
Medulloblastoma     Sensorineural hearing loss     Cerebellar liponeurocytoma

Find genes that share disorders with ATOH1           About GenesLikeMe

2 Novoseek inferred disease relationships for ATOH1 gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
colon tumor 42.5 3 15342386 (1), 16382053 (1)
colon cancer 26.2 7 18275842 (3), 15342386 (1), 16382053 (1)

Genetic Association Database (GAD): ATOH1

Export disorders for ATOH1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ATOH1 gene, integrated from 10 sources (see all 59):
(articles sorted by number of sources associating them with ATOH1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis. (PubMed id 8872459)1, 2, 3 Ben-Arie N....Zoghbi H.Y. (Hum. Mol. Genet. 1996)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene atonal homolog 1 (ATOH1, HATH1, MATH1) in neuroendocrine tumors. (PubMed id 17549667)1, 9 Westerman B.A....Oudejans C.B. (Int. J. Biol. Markers 2007)
  4. The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math1. (PubMed id 16831200)1, 9 Mutoh H....Sugano K. ( research in biological diversity 2006)
  5. Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state of colon cancer. (PubMed id 18275842)1, 9 Aragaki M....Watanabe M. (Biochem. Biophys. Res. Commun. 2008)
  6. A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma. (PubMed id 16382053)1, 9 Leow C.C....Gao W.Q. (Ann. N. Y. Acad. Sci. 2005)
  7. Molecular characterization and mapping of ATOH7, a human atonal homolog with a predicted role in retinal ganglion cell development. (PubMed id 11889557)1, 9 Brown N.L.... Glaser T. (Mamm. Genome 2002)
  8. Atonal homolog 1 expression in lung cancer correlates with inhibitors of the Wnt pathway as well as the differentiation and primary tumor stage. (PubMed id 23030416)1 Xu H.T....Wang E.H. (APMIS 2013)
  9. The genetics of hair cell development and regeneration. (PubMed id 23724999)1 Groves A.K....Fekete D.M. (Annu. Rev. Neurosci. 2013)
  10. The acquisition of malignant potential in colon cancer is regulated by the stabilization of Atonal homolog 1 protein. (PubMed id 23333391)1 Kano Y....Watanabe M. (Biochem. Biophys. Res. Commun. 2013)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 474 HGNC: 797 AceView: ATOH1 Ensembl:ENSG00000172238 euGenes: HUgn474
ECgene: ATOH1 H-InvDB: ATOH1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ATOH1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ATOH1 gene:
Search GeneIP for patents involving ATOH1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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