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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ATG9A Gene

protein-coding   GIFtS: 54
GCID: GC02M220074

Autophagy Related 9A

(Previous names: APG9 autophagy 9-like 1 (S. cerevisiae), ATG9 autophagy...)
(Previous symbol: APG9L1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Autophagy Related 9A1 2     MGD32082
APG9L11 2 3 5     APG9 Autophagy 9-Like 12
APG9-Like 12 3     ATG9 Autophagy Related 9 Homolog A2
mATG92 3     Autophagy 9-Like 1 Protein2
APG9 Autophagy 9-Like 1 (S. Cerevisiae)1     Autophagy-Related Protein 9A2
ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae)1     

External Ids:    HGNC: 224081   Entrez Gene: 790652   Ensembl: ENSG000001989257   OMIM: 6122045   UniProtKB: Q7Z3C63   

Export aliases for ATG9A gene to outside databases

Previous GC identifers: GC02M219911 GC02M219792 GC02M211937


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ATG9A Gene: 
ATG9A (autophagy related 9A) is a protein-coding gene. Diseases associated with ATG9A include meningoencephalitis, and endotheliitis. GO annotations related to this gene include protein binding. An important paralog of this gene is ATG9B.

UniProtKB/Swiss-Prot: ATG9A_HUMAN, Q7Z3C6
Function: Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in
the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for
formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late
endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires
ULK1, ATG13 and SUPT20H

Gene Wiki entry for ATG9A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_005403.17  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ATG9A gene promoter:
         E2F   AP-1   MyoD   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATG9A promoter sequence
   Search SABiosciences Chromatin IP Primers for ATG9A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATG9A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q35   Ensembl cytogenetic band:  2q35   HGNC cytogenetic band: 2q35

ATG9A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATG9A gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M220074:  view genomic region     (about GC identifiers)

Start:
220,074,494 bp from pter      End:
220,094,439 bp from pter
Size:
19,946 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ATG9A_HUMAN, Q7Z3C6 (See protein sequence)
Recommended Name: Autophagy-related protein 9A  
Size: 839 amino acids; 94447 Da
Subunit: Interacts with SUPT20H
Subcellular location: Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Golgi apparatus,
trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin
treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The
starvation-induced redistribution depends on ULK1, ATG13, as well as SH3GLB1
Sequence caution: Sequence=BAB13882.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB15246.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB55119.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q3ZAQ6 Q6P0N7 Q7Z317 Q7Z320 Q8NDK6 Q8WU65 Q9BVL5 Q9H6L1 Q9HAG7
Alternative splicing: 3 isoforms:  Q7Z3C6-1   Q7Z3C6-2   Q7Z3C6-3   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for ATG9A: NX_Q7Z3C6

Explore proteomics data for ATG9A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7Z3C6

  • ATG9A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ATG9A Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001070666.1  NP_076990.4  

    ENSEMBL proteins: 
     ENSP00000398528   ENSP00000386482   ENSP00000379983   ENSP00000386710   ENSP00000355173  
     ENSP00000386535   ENSP00000400234   ENSP00000396404   ENSP00000401530   ENSP00000404750  
     ENSP00000409164   ENSP00000393708   ENSP00000406785   ENSP00000413569   ENSP00000390704  
     ENSP00000398425   ENSP00000416435   ENSP00000394345  

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    Cloud-Clone Corp. Proteins for ATG9A 

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000421autophagic vacuole membrane IEA--
    GO:0005737cytoplasm ----
    GO:0005770late endosome ----
    GO:0005776autophagic vacuole ----
    GO:0005789endoplasmic reticulum membrane IEA--

    ATG9A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR007241 Autophagy-rel_prot_9

    Graphical View of Domain Structure for InterPro Entry Q7Z3C6

    ProtoNet protein and cluster: Q7Z3C6

    UniProtKB/Swiss-Prot: ATG9A_HUMAN, Q7Z3C6
    Similarity: Belongs to the ATG9 family


    ATG9A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ATG9A_HUMAN, Q7Z3C6
    Function: Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in
    the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for
    formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late
    endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires
    ULK1, ATG13 and SUPT20H

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19893488
    GO:0015002heme-copper terminal oxidase activity ----
         
    ATG9A for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ATG9A:
     Increased gamma-H2AX phosphory  Large nuclei 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Atg9a):
     cellular  immune system  mortality/aging 

    ATG9A for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Atg9atm1Aki for ATG9A

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ATG9A 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATG9A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/92 Interacting proteins for ATG9A (Q7Z3C61, 2, 3 ENSP000003551734) via UniProtKB, MINT, STRING, and/or I2D (see all 92)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TBK1Q9UHD21, 3, ENSP000003299674EBI-727146,EBI-356402 I2D: score=1 STRING: ENSP00000329967
    TGOLN2O434932, 3, ENSP000003666034MINT-8142052 I2D: score=1 STRING: ENSP00000366603
    MAPK6Q166592, 3MINT-8260735 I2D: score=2 
    SUPT20HQ8NEM72, ENSP000002188944MINT-7557407 MINT-7557250 MINT-7557367 MINT-7557337 MINT-7557381 MINT-7557272 MINT-7557312 MINT-7557352 STRING: ENSP00000218894
    ENSG00000096150P622693I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000045autophagic vacuole assembly IMP15755735
    GO:0006914autophagy ----
    GO:0015031protein transport IEA--
    GO:0034067protein localization to Golgi apparatus IEA--
    GO:0045087innate immune response IEA--

    ATG9A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ATG9A

    Search CenterWatch for drugs/clinical trials and news about ATG9A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ATG9A gene (2 alternative transcripts): 
    NM_001077198.2  NM_024085.4  

    Unigene Cluster for ATG9A:

    Autophagy related 9A
    Hs.323363  [show with all ESTs]
    Unigene Representative Sequence: BX537984
    18/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22):
    ENST00000446716(uc002vkc.2 uc010fwe.2 uc010zku.1) ENST00000409033(uc002vkd.1)
    ENST00000396761(uc002vke.1 uc002vkf.1) ENST00000409618 ENST00000361242
    ENST00000475339 ENST00000409422 ENST00000429920 ENST00000431715 ENST00000436856
    ENST00000457841 ENST00000428226 ENST00000412355 ENST00000432520 ENST00000439812
    ENST00000456708 ENST00000466217 ENST00000486766
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    Additional mRNA sequence: 

    AK021732.1 AK025822.1 AK027448.1 AK056595.1 AK289755.1 AK302521.1 AK315553.1 AL833865.1 
    BC001098.2 BC001206.1 BC021202.2 BX537984.1 BX538192.1 BX538198.1 

    23 DOTS entries:

    DT.114586  DT.40106917  DT.100713879  DT.100869508  DT.100650765  DT.95110029  DT.92072228  DT.95258709 
    DT.100859437  DT.95257977  DT.95258693  DT.121017571  DT.92072274  DT.100650770  DT.100767825  DT.121017532 
    DT.121017581  DT.121017672  DT.85104287  DT.95127240  DT.95258691  DT.91927823  DT.95258694 

    24/299 AceView cDNA sequences (see all 299):

    BP346414 AI698963 BQ049564 AL701566 BC065534 BQ681220 BM915365 CR617520 
    AI863325 BF981293 BX355626 CD631903 BM915540 BM701420 BU521407 BX110282 
    AU118953 AA459390 BG703383 BM555062 BI561988 BX355625 AL529296 BM913526 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ATG9A (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^
    SP1:                    -     -                                                                                                                       -         
    SP2:                    -     -                                                                                   -     -                             -         
    SP3:                    -     -     -                                                                                                                 -         
    SP4:                    -                                                                                                                                       
    SP5:                    -     -                                                                                                                                 

    ExUns: 16 ^ 17 ^ 18a · 18b
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for ATG9A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ATG9A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGGACTGC
    ATG9A Expression
    About this image


    See ATG9A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ATG9A

    SOURCE GeneReport for Unigene cluster: Hs.323363
        SABiosciences Expression via Pathway-Focused PCR Array including ATG9A: 
              Autophagy in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATG9A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ATG9A gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atg9a1 , 5 autophagy-related 9A (yeast)5
    autophagy related 9A1
    91.3(n)1
    97.97(a)1
      1 (38.62 cM)5
    2458601  NM_001003917.31  NP_001003917.21 
     751808665 
    chicken
    (Gallus gallus)
    Aves ATG9A1 ATG9 autophagy related 9 homolog A (S. cerevisiae) 76.95(n)
    83.37(a)
      425722  NM_001034821.1  NP_001029993.1 
    lizard
    (Anolis carolinensis)
    Reptilia ATG9A6
    Uncharacterized protein
    82(a)
    1 ↔ 1
    1(95789442-95807640)
    zebrafish
    (Danio rerio)
    Actinopterygii atg9a1 ATG9 autophagy related 9 homolog A (S. cerevisiae) 70.13(n)
    75.34(a)
      100009663  NM_001083031.1  NP_001076500.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Atg91 Autophagy-specific gene 9 53.96(n)
    44.75(a)
      36821  NM_137270.3  NP_611114.1 
    worm
    (Caenorhabditis elegans)
    Secernentea atg-91 Protein ATG-9 50.09(n)
    40.56(a)
      178561  NM_182384.1  NP_872184.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ATG9(YDL149W)4 Transmembrane protein involved in forming Cvt and autophagic more   --   4(184925-187918) 851406  NP_010132.1 


    ENSEMBL Gene Tree for ATG9A (if available)
    TreeFam Gene Tree for ATG9A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ATG9A gene
    ATG9B2  
    1 SIMAP similar gene for ATG9A using alignment to 12 protein entries:     ATG9A_HUMAN (see all proteins):
    ATG9B

    ATG9A for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for ATG9A
    PGOHUM00000262012 PGOHUM00000262013


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/221 SNPs in ATG9A are shown (see all 221)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs22766331,2
    C,F,A,H--220085845(+) AGGGCG/AGTGGT 4 /T syn1 ese322Minor allele frequency- A:0.09EA NA NS WA CSA EU 2832
    rs1151939021,2
    C,F--220085847(+) GGCAGT/CGGTCT 4 /T /A mis11Minor allele frequency- C:0.03WA 118
    rs2008582821,2
    C--220085922(+) CCGGGC/GGCCCT 4 P A mis10--------
    rs2018430791,2
    C--220085975(+) CCCGGC/TGGTGC 4 H R mis10--------
    rs1438141141,2
    C--220086043(+) GGGCTC/TGTTAG 2 -- int10--------
    rs1878830721,2
    --220086178(+) TACCTC/TTGATC 2 -- int10--------
    rs99898541,2
    C,F,A,H--220086280(+) ACTGAT/CGGTCT 2 -- int128Minor allele frequency- C:0.29NS EA NA CSA WA 2780
    rs1923602851,2
    --220086350(+) CCAGCC/GCTTGT 2 -- int10--------
    rs1472810381,2
    --220086403(+) AATAAA/GGAAAA 2 -- int10--------
    rs1397653151,2
    C--220086417(+) ATGATA/GTGTCA 2 -- int10--------

    HapMap Linkage Disequilibrium report for ATG9A (220074494 - 220094439 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ATG9A:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv834543CNV Loss17160897
    nsv875869CNV Loss21882294
    nsv875870CNV Gain+Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612204    OMIM disorders: --

    2 diseases for ATG9A:    About MalaCards
    meningoencephalitis    endotheliitis


    ATG9A for disorders           About GeneDecksing

    Genetic Association Database (GAD): ATG9A
    Human Genome Epidemiology (HuGE) Navigator: ATG9A (2 documents)

    Export disorders for ATG9A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ATG9A gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with ATG9A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Bif-1 regulates Atg9 trafficking by mediating the fis sion of Golgi membranes during autophagy. (PubMed id 21068542)1, 2 Takahashi Y....Wang H.G. (2011)
    2. MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage he ad and neck cancer. (PubMed id 20819778)1, 4 Zhang X....Wu X. (2010)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP. (PubMed id 19893488)1, 2 Webber J.L. and Tooze S.A. (2010)
    5. Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. (PubMed id 16940348)1, 2 Young A.R....Tooze S.A. (2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    7. Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast. (PubMed id 15755735)1, 2 Yamada T....Scherer S.W. (2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    10. Dynamic and transient interactions of Atg9 with autoph agosomes, but not membrane integration, are required for autophagy. (PubMed id 22456507)1 Orsi A....Tooze S.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79065 HGNC: 22408 AceView: FLJ22169 Ensembl:ENSG00000198925 euGenes: HUgn79065
    ECgene: ATG9A H-InvDB: ATG9A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ATG9A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ATG9A gene:
    Search GeneIP for patents involving ATG9A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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