Aliases for ATG14 Gene
External Ids for ATG14 Gene
Previous Symbols for ATG14 Gene
GeneCards Summary for ATG14 Gene
ATG14 (Autophagy Related 14) is a Protein Coding gene. Diseases associated with ATG14 include human granulocytic anaplasmosis. Among its related pathways are Senescence and Autophagy and Regulation of autophagy.
UniProtKB/Swiss-Prot for ATG14 Gene
Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (By similarity).