ATG13 Gene
protein-coding GIFtS: 50
GCID: GC11P046638
|
|
autophagy related 13(Previous names: KIAA0652, ATG13 autophagy related 13 homolog (S. cerevisiae)...)
(Previous symbol: KIAA0652)
| |
Aliases
for ATG13 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Autophagy Related 131 2 | | KIAA06521 2 3 | | ATG13 Autophagy Related 13 Homolog (S. Cerevisiae)1 | | ATG13 Autophagy Related 13 Homolog2 | | Autophagy-Related Protein 132 |
Export aliases for ATG13 gene to outside databasesPrevious GC identifer: GC11P046345 |
Summaries
for ATG13 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ATG13_HUMAN, O75143Function: Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway thatregulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of theATG13-ULK1-RB1CC1 complex
Gene Wiki entry for ATG13 (Autophagy-related protein 13)
|
Genomic Views
for ATG13 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ATG13
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATG13
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATG13 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p11.2 Ensembl cytogenetic band: 11p11.2 HGNC cytogenetic band: 11p11.2ATG13 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P046638: view genomic region
(about GC identifiers)
Start:
|
46,638,826 bp from pter |
End:
|
46,696,368 bp from pter |
Size:
|
57,543 bases |
Orientation:
|
plus strand |
|
Proteins
for ATG13 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ATG13_HUMAN, O75143 (See
protein sequence)Recommended Name: Autophagy-related protein 13 Size: 517 amino acids; 56572 Da
Subunit: Part of a complex consisting of ATG13, ULK1 and RB1CC1. Interacts with ATG101. Interacts with ULK1 (viaC-terminus). Interacts with ULK2 (via C-terminus)
Subcellular location: Cytoplasm, cytosol (By similarity). Preautophagosomal structure (By similarity). Note=Understarvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolationmembrane sequesters a portion of the cytoplasm resulting in autophagosome formation (By similarity)
Sequence caution: Sequence=BAA31627.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=BAD97323.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B4DFI4 D3DQQ1 D3DQQ2 E9PQZ8 Q53EN6 Q9BRL3 Q9H8B0Alternative splicing: 5 isoforms: O75143-1 O75143-2 O75143-3 O75143-4 O75143-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ATG13: NX_O75143
Post-translational modifications:
Phosphorylated by ULK1 and ULK2. Phosphorylation status depends on nutrient-rich conditions; dephosphorylated duringstarvation or following treatment with rapamycin (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75143
ATG13 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001136145.1 NP_001192048.1 NP_001192049.1 NP_001192050.1 NP_001192051.1 NP_055556.2
ENSEMBL proteins: ENSP00000463808 ENSP00000464274 ENSP00000433756 ENSP00000436931 ENSP00000463550 ENSP00000463998 ENSP00000434390 ENSP00000431974 ENSP00000462644 ENSP00000462167 ENSP00000433543 ENSP00000464091 ENSP00000352500 ENSP00000432412 ENSP00000378919 ENSP00000433052 ENSP00000434125 ENSP00000436174 ENSP00000431877 ENSP00000437191 ENSP00000400642 ENSP00000310321 ENSP00000404900
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ATG13 for ontologies About GeneDecksing
ATG13 Antibody Products:
Assay Products for ATG13: |
Protein
Domains /
Families
for ATG13 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATG13 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O75143ProtoNet protein and cluster: O75143 UniProtKB/Swiss-Prot: ATG13_HUMAN, O75143Similarity: Belongs to the ATG13 metazoan family |
Function
for ATG13 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ATG13_HUMAN, O75143Function: Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway thatregulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of theATG13-ULK1-RB1CC1 complex
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATG13 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATG13 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 6): ATG13 (NM_001205120) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATG13 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATG13 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATG13 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ATG13 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for ATG13:
|
Pathways & Interactions
for ATG13 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | mTOR signaling pathway | | | 2 | Senescence and Autophagy | |
2  BioSystems Pathways for ATG13
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATG13
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/182 Interacting proteins for ATG13 (O751431, 2, 3 ENSP000003103214) via UniProtKB, MINT, STRING, and/or I2D (see all 182)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
ATG13 for ontologies About GeneDecksing
|
Drugs & Compounds
for ATG13 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ATG13
Search CenterWatch for drugs/clinical trials and news about ATG13
|
Transcripts
for ATG13 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATG13 gene (6 alternative transcripts): NM_001142673.2 NM_001205119.1 NM_001205120.1 NM_001205121.1 NM_001205122.1 NM_014741.4 Unigene Cluster for ATG13: Autophagy related 13 Hs.127403 [show with all ESTs]Unigene Representative Sequence: NM_00120511918/34 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 34): ENST00000580238 ENST00000579280 ENST00000581416 ENST00000529655 ENST00000526715
ENST00000533325 ENST00000581438 ENST00000583249 ENST00000530500 ENST00000526508
ENST00000578626 ENST00000577256 ENST00000524625 ENST00000530942 ENST00000534610
ENST00000582547 ENST00000359513 ENST00000528494
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATG13 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATG13 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 6): ATG13 (NM_001205120) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATG13 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATG13 |
Additional cDNA sequence: AB014552.1 AF052175.1 AK000705.1 AK023867.1 AK223603.1 AK289641.1 AK293109.1 AK296526.1 AK315925.1 BC001331.1 BC002378.2 BC006191.2 24/39 DOTS entries (see all 39): DT.95217300 DT.101984421 DT.95208193 DT.456412 DT.95217336 DT.120718171 DT.100845976 DT.120718182 DT.92449871 DT.100845975 DT.120718262 DT.97864334 DT.40131395 DT.120718178 DT.95217256 DT.97792090 DT.104339 DT.120718223 DT.92449892 DT.92449897 DT.120718196 DT.120718259 DT.95345803 DT.97864332 24/453 AceView cDNA sequences (see all 453): AI915504 BX342671 BQ025792 BG191611 AI420266 BM746826 BM557798 BQ925134 AU126372 BG260593 NM_014741 CD518744 BF724357 Z45058 CD675328 BU162490 BX402959 AU125065 BE741158 W03546 AI142351 AA132074 BM550243 BU151125
GeneLoc Exon Structure
5/31 Alternative Splicing Database (ASD) splice patterns (SP) for ATG13 (see all 31) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | · | 4d | · | 4e | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | - | | |
| SP2: | | | | | | | | | - | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | - | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | - | | |
| SP4: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP5: | | | | | | | | | - | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 13b | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 | ^ | 23a | · | 23b | ^ | 24 | ^ | 25 |
|---|
|
| SP1: | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ATG13
|
Expression
for ATG13 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATG13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAAATAAAA
About this image
See ATG13 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATG13
SOURCE GeneReport for Unigene cluster: Hs.127403
SABiosciences Custom PCR Arrays for ATG13
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATG13
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ATG13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATG13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATG13 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATG13 |
Orthologs
for ATG13 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ATG13 gene from 7/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Atg131 , 5 |
ATG13 autophagy related 13 homolog (S. cerevisiae)5
autophagy related 131 |
88.94(n)1
94.36(a)1 |
|
2 (50.63 cM)5
518971 NM_145528.31 NP_663503.11
916746185 |
chicken
(Gallus gallus) |
Aves |
ATG131 |
ATG13 autophagy related 13 homolog (S. cerevisiae) |
83.53(n)
93.39(a) |
|
423192 XM_003641388.1 XP_003641436.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ATG136 |
-- |
88(a) |
1 ↔ 1 |
1(43013610-43038625) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.178972 |
Xenopus laevis transcribed sequence with weak similarity more |
80.5(n) |
|
BU900721.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc635262 |
hypothetical protein MGC63526 |
77.63(n) |
|
393405 BC054904.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Atg136 |
Autophagy-specific gene 13 |
25(a) |
1 ↔ 1 |
3R(4175524-4178539) |
worm
(Caenorhabditis elegans) |
Secernentea |
atg-136 |
Autophagy-related protein 13 homolog |
22(a) |
1 ↔ 1 |
III(8155925-8158180) |
ENSEMBL Gene Tree for ATG13 (if available)
TreeFam Gene Tree for ATG13 (if available) |
Paralogs
for ATG13 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ATG13 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATG13 (46638826 - 46696368 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ATG13: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATG13 |
|
Disorders
/ Diseases
for ATG13 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATG13 for disorders About GeneDecksing
OMIM gene information: 615088
OMIM disorders: --
2  diseases for ATG13: About MalaCardspharyngitis neuronitis
Export disorders for ATG13 gene to outside databases
|
Publications
for ATG13 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATG13 gene, integrated from 9 sources (see all 30):
(articles sorted by number of sources associating them with ATG13) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Atg101, a novel mammalian autophagy protein interacting with Atg13. (PubMed id 19597335)1, 2 Hosokawa N....Mizushima N. (2009)
- Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. (PubMed id 19211835)1, 2 Hosokawa N....Mizushima N. (2009)
- A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy. (PubMed id 19287211)1, 2 Mercer C.A.... Dennis P.B. (2009)
- Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism. (PubMed id 18936157)1, 2 Chan E.Y....Tooze S.A. (2009)
- ATG genes involved in non-selective autophagy are con served from yeast to man, but the selective Cvt and pexophagy pathways also req uire organism-specific genes. (PubMed id 17204848)1, 3 Meijer W.H....Kiel J.A. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2 Ishikawa K.... Ohara O. (1998)
- ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs. (PubMed id 23043107)1 Alemu E.A....Johansen T. (2012)
- TGFb-activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy. (PubMed id 21976705)1 Takaesu G....Yoshimura A. (2012)
|
External Searches for ATG13 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ATG13 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ATG13 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ATG13 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ATG13 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ATG13 gene:
Search GeneIP for patents involving ATG13
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ATG13 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ATG13 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATG13 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATG13 | | | OriGene Protein Over-expression Lysate for ATG13 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATG13 | | OriGene 3'-UTR Clone for ATG13 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATG13 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATG13 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ATG13 | | OriGene Custom Protein Services for ATG13 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATG13 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATG13 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATG13 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATG13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATG13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATG13 |
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| | Antibodies & Assays for ATG13 |
| | | | Search Tocris compounds for ATG13 |
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 | | | ATG13 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATG13 |
|  |  |  | | | | ThermoFisher Antibodies for ATG13 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATG13 |
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