Aliases for ATE1 Gene
External Ids for ATE1 Gene
Previous GeneCards Identifiers for ATE1 Gene
This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
GeneCards Summary for ATE1 Gene
ATE1 (Arginyltransferase 1) is a Protein Coding gene. Diseases associated with ATE1 include distal 10q deletion syndrome. GO annotations related to this gene include arginyltransferase activity.
UniProtKB/Swiss-Prot for ATE1 Gene
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).