Aliases for ATAT1 Gene
External Ids for ATAT1 Gene
Previous Symbols for ATAT1 Gene
GeneCards Summary for ATAT1 Gene
ATAT1 (Alpha Tubulin Acetyltransferase 1) is a Protein Coding gene. Among its related pathways are Metabolism and Carbon metabolism. GO annotations related to this gene include tubulin N-acetyltransferase activity.
UniProtKB/Swiss-Prot for ATAT1 Gene
Specifically acetylates Lys-40 in alpha-tubulin on the lumenal side of microtubules. Required for normal sperm flagellar function. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.