Aliases for ATAT1 Gene
External Ids for ATAT1 Gene
Previous HGNC Symbols for ATAT1 Gene
Previous GeneCards Identifiers for ATAT1 Gene
GeneCards Summary for ATAT1 Gene
ATAT1 (Alpha Tubulin Acetyltransferase 1) is a Protein Coding gene. Among its related pathways are Organelle biogenesis and maintenance and Metabolism. GO annotations related to this gene include coenzyme binding and tubulin N-acetyltransferase activity.
UniProtKB/Swiss-Prot for ATAT1 Gene
Specifically acetylates Lys-40 in alpha-tubulin on the lumenal side of microtubules. Required for normal sperm flagellar function. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.