ATAD3C Gene
protein-coding GIFtS: 39
GCID: GC01P001376
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ATPase family, AAA domain containing 3C
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Aliases
for ATAD3C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ATPase Family, AAA Domain Containing 3C1 2 | | FLJ345991 | | ATPase Family AAA Domain-Containing Protein 3C2 | | ATPase Family, AAA Domain Containing 3A2 |
Export aliases for ATAD3C gene to outside databasesPrevious GC identifers: GC01P001471 GC01P001375 GC01P000662 |
Summaries
for ATAD3C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ATAD3C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004350.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ATAD3C gene promoter:
GR Bach1 AML1a Pax-6 XBP-1 Arnt C/EBPalpha HEN1 NRF-2 ARP-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ATAD3C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATAD3C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.33 Ensembl cytogenetic band: 1p36.33 HGNC cytogenetic band: 1p36.33ATAD3C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P001376: view genomic region
(about GC identifiers)
Start:
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1,385,069 bp from pter |
End:
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1,405,538 bp from pter |
Size:
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20,470 bases |
Orientation:
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plus strand |
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Proteins
for ATAD3C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ATD3C_HUMAN, Q5T2N8 (See
protein sequence)Recommended Name: ATPase family AAA domain-containing protein 3C Size: 411 amino acids; 46380 Da
Sequence caution: Sequence=AAI01212.1; Type=Erroneous translation; Note=Wrong choice of frame; Sequence=AAI01213.1;Type=Erroneous translation; Note=Wrong choice of frame; Sequence=BAC04369.1; Type=Erroneous translation; Note=Wrongchoice of frame; Sequence=CAI22067.1; Type=Erroneous gene model prediction; Sequence=CAI22656.1; Type=Erroneous genemodel prediction;
Secondary accessions: Q8N1Z5Explore the universe of human proteins at neXtProt for ATAD3C: NX_Q5T2N8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5T2N8
ATAD3C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001034300.2
ENSEMBL proteins: ENSP00000368062 ENSP00000464661
Human Recombinant Protein Products:
ATAD3C Antibody Products:
Assay Products for ATAD3C: |
Protein
Domains /
Families
for ATAD3C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ATAD3C for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5T2N8ProtoNet protein and cluster: Q5T2N8 UniProtKB/Swiss-Prot: ATD3C_HUMAN, Q5T2N8Similarity: Belongs to the AAA ATPase family |
Function
for ATAD3C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATAD3C (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATAD3C (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ATAD3C (NM_001039211) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATAD3C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATAD3C |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATAD3C |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005524 | ATP binding |
IEA | -- | | GO:0017111 | nucleoside-triphosphatase activity |
IEA | -- |
ATAD3C for ontologies About GeneDecksing
|
Pathways & Interactions
for ATAD3C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ATAD3C
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ATAD3C (Q5T2N83 ENSP000003680624) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for ATAD3C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ATAD3C
Search CenterWatch for drugs/clinical trials and news about ATAD3C / ATD3C
|
Transcripts
for ATAD3C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ATAD3C gene: NM_001039211.2 Unigene Cluster for ATAD3C: ATPase family, AAA domain containing 3C Hs.724767 [show with all ESTs]Unigene Representative Sequence: NM_0010392113 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000378785(uc001aft.2) ENST00000475091 ENST00000484537
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATAD3C (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATAD3C (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ATAD3C (NM_001039211) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ATAD3C | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATAD3C |
Additional cDNA sequence: AK091918.1 AK094502.1 BC101211.1 BC101212.1 5 DOTS entries: DT.100789537 DT.91794510 DT.91769413 DT.65286225 DT.75124626 24/466 AceView cDNA sequences (see all 466): AA555166 BM668156 BQ219220 AK024028 BI160963 CF127746 BU956220 BQ955748 NM_031921 BG829746 BM561824 BQ943893 BQ051894 BU955794 CA454930 BQ028996 BC002542 BM699613 BG743097 CF242892 BM310993 AL834179 AI827252 AU143103
GeneLoc Exon Structure
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Expression
for ATAD3C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ATAD3C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGGCAGAG
About this image
See ATAD3C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ATAD3C
SOURCE GeneReport for Unigene cluster: Hs.724767
SABiosciences Custom PCR Arrays for ATAD3C
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATAD3C
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ATAD3C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATAD3C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATAD3C | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATAD3C |
Orthologs
for ATAD3C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ATAD3C gene from 7/20 species (see all 20) About this table
ENSEMBL Gene Tree for ATAD3C (if available)
TreeFam Gene Tree for ATAD3C (if available) |
Paralogs
for ATAD3C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ATAD3C gene
- ATAD3B2 ATAD3A2 PSMC32
3 SIMAP similar genes for ATAD3C using alignment to 2 protein entries: ATD3C_HUMAN (see all proteins):ATAD3A ATAD3B DKFZp761L1023
ATAD3C for paralogs About GeneDecksing
|
Genomic Variants
for ATAD3C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ATAD3C (1385069 - 1405538 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ATAD3C
2 CNVs: 30362 3276 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATAD3C |
|
Disorders
/ Diseases
for ATAD3C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ATAD3C for disorders About GeneDecksing
1  disease for ATAD3C: About MalaCardsmalaria
Export disorders for ATAD3C gene to outside databases
|
Publications
for ATAD3C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ATAD3C gene integrated from 9 sources:
(articles sorted by number of sources associating them with ATAD3C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- [ATAD3, a vital membrane-bound mitochondrial ATPase in volved in tumor progression]. (PubMed id 22192748)1 Li S. and Rousseau D. (2011)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ATAD3C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ATAD3C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing ATAD3C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ATAD3C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ATAD3C | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ATAD3C gene:
Search GeneIP for patents involving ATAD3C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ATAD3C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ATAD3C | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ATAD3C | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ATAD3C | | | OriGene Protein Over-expression Lysate for ATAD3C | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ATAD3C | | OriGene 3'-UTR Clone for ATAD3C | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ATAD3C | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ATAD3C | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ATAD3C | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ATAD3C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ATAD3C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ATAD3C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ATAD3C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ATAD3C |
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 | | | ATAD3C Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATAD3C |
|  |  |  | | | | Search ThermoFisher Antibodies for ATAD3C |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ATAD3C |
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