Aliases for ATAD3B Gene
External Ids for ATAD3B Gene
Previous GeneCards Identifiers for ATAD3B Gene
ATAD3A (MIM 612316) and ATAD3B are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008]
GeneCards Summary for ATAD3B Gene
ATAD3B (ATPase Family, AAA Domain Containing 3B) is a Protein Coding gene. GO annotations related to this gene include nucleoside-triphosphatase activity. An important paralog of this gene is ATAD3A.
UniProtKB/Swiss-Prot for ATAD3B Gene
May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes.