External Ids for ATAD3A Gene
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008]
GeneCards Summary for ATAD3A Gene
ATAD3A (ATPase Family, AAA Domain Containing 3A) is a Protein Coding gene. GO annotations related to this gene include nucleoside-triphosphatase activity. An important paralog of this gene is ATAD3C.
UniProtKB/Swiss-Prot for ATAD3A Gene
Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis.