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ATAD3A Gene

protein-coding   GIFtS: 50
GCID: GC01P001447

ATPase Family, AAA Domain Containing 3A

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ATPase Family, AAA Domain Containing 3A1 2
ATPase Family AAA Domain-Containing Protein 3A2

External Ids:    HGNC: 255671   Entrez Gene: 552102   Ensembl: ENSG000001977857   OMIM: 6123165   UniProtKB: Q9NVI73   

Export aliases for ATAD3A gene to outside databases

Previous GC identifers: GC01P001387 GC01P001532 GC01P001374 GC01P001439 GC01P000720


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ATAD3A Gene:
ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large
mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 (PubMed 17210950)).(supplied by
OMIM, Sep 2008)

GeneCards Summary for ATAD3A Gene:
ATAD3A (ATPase family, AAA domain containing 3A) is a protein-coding gene. GO annotations related to this gene include nucleoside-triphosphatase activity. An important paralog of this gene is ATAD3B.

UniProtKB/Swiss-Prot: ATD3A_HUMAN, Q9NVI7
Function: Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism
and cellular level. May play an important in mitochondrial protein synthesis. May also participate in
mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability.
Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the ATAD3A gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B2   oct-B3   Arnt   POU2F2   POU2F2C   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidATAD3A promoter sequence
   Search Chromatin IP Primers for ATAD3A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ATAD3A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.33   Ensembl cytogenetic band:  1p36.33   HGNC cytogenetic band: 1p36.33

ATAD3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATAD3A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P001447:  view genomic region     (about GC identifiers)

Start:
1,447,523 bp from pter      End:
1,470,067 bp from pter
Size:
22,545 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ATD3A_HUMAN, Q9NVI7 (See protein sequence)
Recommended Name: ATPase family AAA domain-containing protein 3A  
Size: 634 amino acids; 71369 Da
Subunit: Can form homooligomers. Homodimer formation at the N-terminus may be regulated by ATP and is required for
the interaction with the inner surface of the mitochondrial outer membrane and correct mitochondrial homeostasis.
Interacts with components of the mitochondrial ribosome and with other proteins involved in mitochondrial RNA
metabolism. May also interact with protein involved in lipid metabolism, including STARD9. May interact with
FAM210A. Interacts with GADD45GIP1. Interacts with S100B in a Ca(+2)- and Zn(+2)-dependent manner; this
interaction probably occurs in the cytosol prior to mitochondrial targeting. S100B could assist ATAD3A
cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. Interacts with
HSP60/HSPD1. Forms heterooligomers with ATAD3B; this interaction may affect ATAD3A activity
Secondary accessions: B3KPB3 D2K8Q1 G3V1I6 Q5SV23 Q8N275 Q96A50
Alternative splicing: 3 isoforms:  Q9NVI7-1   Q9NVI7-2   Q9NVI7-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ATAD3A: NX_Q9NVI7

Explore proteomics data for ATAD3A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys406, Lys442, Lys621
  • Modification sites at PhosphoSitePlus

  • See ATAD3A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001164006.1  NP_001164007.1  NP_060658.3  

    ENSEMBL proteins: 
     ENSP00000368031   ENSP00000368030   ENSP00000339421   ENSP00000383631   ENSP00000439290  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    AATP: ATPases / AAA-type

    4 InterPro protein domains:
     IPR003959 ATPase_AAA_core
     IPR027417 P-loop_NTPase
     IPR003593 AAA+_ATPase
     IPR021911 DUF3523

    Graphical View of Domain Structure for InterPro Entry Q9NVI7

    ProtoNet protein and cluster: Q9NVI7

    UniProtKB/Swiss-Prot: ATD3A_HUMAN, Q9NVI7
    Domain: The transmembrane domain and a C-terminal adjacent region contain all information necessary for
    mitochondrial targeting (PubMed:20154147)
    Similarity: Belongs to the AAA ATPase family


    Find genes that share domains with ATAD3A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ATD3A_HUMAN, Q9NVI7
    Function: Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism
    and cellular level. May play an important in mitochondrial protein synthesis. May also participate in
    mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability.
    Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis
    Induction: Up-regulated by Angiotensin/AGT

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005524ATP binding IEA--
    GO:0017111nucleoside-triphosphatase activity IEA--
         
    Find genes that share ontologies with ATAD3A           About GenesLikeMe


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Atad3a):
     embryogenesis  growth/size/body  mortality/aging 

    Find genes that share phenotypes with ATAD3A           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ATAD3A

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    miRTarBase miRNAs that target ATAD3A:
    hsa-mir-149-5p (MIRT045393), hsa-mir-124-3p (MIRT022238), hsa-mir-92a-3p (MIRT048949), hsa-mir-24-3p (MIRT030419)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ATD3A_HUMAN, Q9NVI7: Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix,
    mitochondrion nucleoid. Note=In the mitochondrial inner membrane, enriched in sites with the potential to form
    contacts with the outer membrane. The N-terminal domain interacts with the inner surface of the mitochondrial
    outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with
    nucleoids
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2
    nucleus2
    extracellular1
    golgi apparatus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral component of membrane IEA--
    GO:0042645mitochondrial nucleoid IEA--

    Find genes that share ontologies with ATAD3A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ATAD3A
    Interactions:

        Search GeneGlobe Interaction Network for ATAD3A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ATAD3A (Q9NVI72, 3 ENSP000003680304) via UniProtKB, MINT, STRING, and/or I2D (see all 359)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RIPK3Q9Y5722, 3MINT-49129 I2D: score=2 
    TNFRSF1AP194382, 3MINT-49348 I2D: score=2 
    TNFRSF1BP203332, 3MINT-49433 I2D: score=2 
    TRADDQ156282, 3MINT-49488 I2D: score=2 
    PTP4A3O753653, ENSP000003322744I2D: score=2 STRING: ENSP00000332274
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    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016049cell growth IMP--
    GO:0043066negative regulation of apoptotic process IMP--

    Find genes that share ontologies with ATAD3A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ATAD3A (ATD3A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ATAD3A gene (3 alternative transcripts): 
    NM_001170535.1  NM_001170536.1  NM_018188.3  

    Unigene Cluster for ATAD3A:

    ATPase family, AAA domain containing 3A
    Hs.23413  [show with all ESTs]
    Unigene Representative Sequence: NM_018188
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000378756(uc001aga.2) ENST00000378755(uc001afz.2) ENST00000339113
    ENST00000439513 ENST00000429957 ENST00000400830 ENST00000536055(uc001agb.2)

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      QuantiFast Probe-based Assays in human, mouse, rat ATAD3A

    Additional mRNA sequence: 

    AK001571.1 AK025865.1 AK056099.1 AK091144.1 AK092833.1 AK310572.1 BC007803.2 BC011814.2 
    BC014101.2 BC033109.1 BC063607.1 GU189416.1 

    19 DOTS entries:

    DT.100789528  DT.75100599  DT.95265763  DT.100031230  DT.121327937  DT.100031226  DT.121327954  DT.95265774 
    DT.97854639  DT.100789525  DT.100789527  DT.100789530  DT.121327912  DT.121327932  DT.75182947  DT.91769413 
    DT.91897777  DT.92048665  DT.99998976 

    Selected AceView cDNA sequences (see all 466):

    BQ028996 BM310993 BG760426 BU159690 BE397300 BQ070791 AI827252 BF062006 
    BQ129356 AU143103 CF242892 BQ642998 CA431591 BQ954571 CA454930 AL834179 
    BQ051894 BC018701 BM699613 BM561824 CA425385 BX104486 AI678769 BC002542 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ATAD3A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCCGATCTT
    ATAD3A Expression
    About this image

    ATAD3A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ATAD3A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.23413

    UniProtKB/Swiss-Prot: ATD3A_HUMAN, Q9NVI7
    Tissue specificity: Overexpressed in lung adenocarcinomas (at protein level)

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ATAD3A gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atad3a1 , 5 ATPase family, AAA domain containing 3A1, 5 83.36(n)1
    92.31(a)1
      4 (87.20 cM)5
    1088881  NM_179203.31  NP_849534.21 
     1557406415 
    chicken
    (Gallus gallus)
    Aves ATAD3A1 ATPase family, AAA domain containing 3A 77.03(n)
    87.5(a)
      419412  XM_004947405.1  XP_004947462.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    80(a)
    1 → many
    AAWZ02037771(1424-14229)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC686162 hypothetical protein MGC68616 75.23(n)    BC060012.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.257322 Transcribed sequence with moderate similarity to protein more 79.74(n)    CA473917.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta bor1 belphegor 65.84(n)
    66.73(a)
      53565  NM_080257.4  NP_524996.1 
    worm
    (Caenorhabditis elegans)
    Secernentea atad-31 atad-3 55.6(n)
    58.63(a)
      174590  NM_063809.6  NP_496210.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G030601 AT3G03060 48.78(n)
    43.2(a)
      821146  NM_111176.2  NP_186956.2 
    rice
    (Oryza sativa)
    Liliopsida Os02g06976001 Os02g0697600 49.68(n)
    40.73(a)
      4330409  NM_001054356.1  NP_001047821.1 


    ENSEMBL Gene Tree for ATAD3A (if available)
    TreeFam Gene Tree for ATAD3A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ATAD3A gene
    ATAD3B2  ATAD3C2  
    3 SIMAP similar genes for ATAD3A using alignment to 3 protein entries:     ATD3A_HUMAN (see all proteins):
    ATAD3B    ATAD3C    DKFZp761L1023

    Find genes that share paralogs with ATAD3A           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for ATAD3A
    PGOHUM00000259546 PGOHUM00000251105


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ATAD3A (see all 845)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1849861881,2
    C--718889(+) CATGCC/TGGTGG 2 -- us2k10--------
    rs29865781,2
    --1445582(-) gatctC/Tagctc 2 -- us2k10--------
    rs1818885831,2
    --1445591(+) TCGCAC/TCATTG 2 -- us2k10--------
    rs1448521861,2
    --1445641(+) ATAAAG/TAACCA 2 -- us2k10--------
    rs1479026941,2
    --1445786(+) AACTCA/CTGGGC 2 -- us2k10--------
    rs1856345291,2
    C--1445827(+) ACTGGC/TGGGGT 2 -- us2k10--------
    rs1162727771,2
    C,F--1445849(+) GCCACC/TGCGCC 2 -- us2k12Minor allele frequency- T:0.03WA NA 238
    rs1905047691,2
    --1445924(+) CCAGGG/TTGGAG 3 -- us2k10--------
    rs1134588561,2
    C--1446221(+) TCAGTC/TGCCCA 3 -- us2k13Minor allele frequency- T:0.08CSA WA EA 240
    rs1807349891,2
    --1446305(+) GAACTC/TGAATA 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for ATAD3A (1447523 - 1470067 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ATAD3A (see all 24):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2658581CNV Deletion23128226
    esv2747807CNV Deletion23290073
    esv2747696CNV Deletion23290073
    esv2747363CNV Deletion23290073
    nsv871421CNV Loss21882294
    nsv871954CNV Loss21882294
    dgv42n71CNV Loss21882294
    dgv10n71CNV Loss21882294
    dgv34n71CNV Loss21882294
    nsv871837CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612316    OMIM disorders: --


    Find genes that share disorders with ATAD3A           About GenesLikeMe

    Genetic Association Database (GAD): ATAD3A
    Human Genome Epidemiology (HuGE) Navigator: ATAD3A (1 document)

    Export disorders for ATAD3A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ATAD3A gene, integrated from 10 sources (see all 49):
    (articles sorted by number of sources associating them with ATAD3A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A. (PubMed id 22664726)1, 2 Merle N....Baudier J. (Mitochondrion 2012)
    2. Topological analysis of ATAD3A insertion in purified human mitochondria. (PubMed id 20349121)1, 2 Hubstenberger A.... Rousseau D. (J. Bioenerg. Biomembr. 2010)
    3. The calcium-dependent interaction between S100B and the mitochondrial AAA ATPase ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A. (PubMed id 20351179)1, 2 Gilquin B....Baudier J. (Mol. Cell. Biol. 2010)
    4. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    5. The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes. (PubMed id 20154147)1, 2 Gilquin B.... Baudier J. (Mol. Cell. Biol. 2010)
    6. ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells. (PubMed id 20332122)1, 2 Fang H.Y.... Chow K.C. (J. Cell Sci. 2010)
    7. The layered structure of human mitochondrial DNA nucleoids. (PubMed id 18063578)1, 2 Bogenhagen D.F.... Burke S. (J. Biol. Chem. 2008)
    8. The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization. (PubMed id 17210950)1, 2 He J.... Holt I.J. (J. Cell Biol. 2007)
    9. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55210 HGNC: 25567 AceView: ATAD3AandATAD3BandFLJ37183 Ensembl:ENSG00000197785 euGenes: HUgn55210
    ECgene: ATAD3A H-InvDB: ATAD3A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ATAD3A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ATAD3A gene:
    Search GeneIP for patents involving ATAD3A

    GeneCards and IP:
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