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ATAD2B Gene

protein-coding   GIFtS: 48
GCID: GC02M023971

ATPase Family, AAA Domain Containing 2B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ATPase Family, AAA Domain Containing 2B1 2
KIAA12403 5
ATPase Family AAA Domain-Containing Protein 2B2
EC 3.5.1.158
EC 3.6.1.38

External Ids:    HGNC: 292301   Entrez Gene: 544542   Ensembl: ENSG000001197787   OMIM: 6153475   UniProtKB: Q9ULI03   

Export aliases for ATAD2B gene to outside databases

Previous GC identifers: GC02M023825 GC02M023711


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ATAD2B Gene:
The protein encoded by this gene belongs to the AAA ATPase family, CDC48 subfamily. This subfamily members in
eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to
the Golgi apparatus. The exact function of this protein is not known. (provided by RefSeq, May 2011)

GeneCards Summary for ATAD2B Gene:
ATAD2B (ATPase family, AAA domain containing 2B) is a protein-coding gene. Diseases associated with ATAD2B include oligodendroglioma, and tuberculosis. GO annotations related to this gene include histone acetyl-lysine binding and nucleoside-triphosphatase activity. An important paralog of this gene is ATAD2.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NT_022184.16  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ATAD2B gene promoter:
         TBP   AhR   HOXA9   HOXA9B   AML1a   MIF-1   Meis-1b   AREB6   TFIID   Meis-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ATAD2B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ATAD2B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p24.1-p23.3   Ensembl cytogenetic band:  2p23.3   HGNC cytogenetic band: 2p24.1-p23.3

ATAD2B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ATAD2B gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M023971:  view genomic region     (about GC identifiers)

Start:
23,971,534 bp from pter      End:
24,149,984 bp from pter
Size:
178,451 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ATD2B_HUMAN, Q9ULI0 (See protein sequence)
Recommended Name: ATPase family AAA domain-containing protein 2B  
Size: 1458 amino acids; 164914 Da
Subunit: Binds acetylated lysine residues in histone H1.4, H2A, H2B, H3 and H4 (in vitro)
Sequence caution: Sequence=BAD18469.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
2 PDB 3D structures from and Proteopedia for ATAD2B:
2DKW (3D)        3LXJ (3D)    
Secondary accessions: B9ZVQ5 Q6ZNA6 Q8N9E7
Alternative splicing: 2 isoforms:  Q9ULI0-1   Q9ULI0-2   

Explore the universe of human proteins at neXtProt for ATAD2B: NX_Q9ULI0

Explore proteomics data for ATAD2B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys447, Lys478
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for ATAD2B (Q9ULI0)
     LFYGPPG  TLILEDS 


    See ATAD2B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001229267.1  NP_060022.1  

    ENSEMBL proteins: 
     ENSP00000238789   ENSP00000370412   ENSP00000392764   ENSP00000415926   ENSP00000403177  

    ATAD2B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ATAD2B

    ATAD2B Antibody Products:

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    Abcam antibodies for ATAD2B
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    ATAD2B Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ATAD2B
    Cloud-Clone Corp. CLIAs for ATAD2B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    AATP: ATPases / AAA-type

    Selected InterPro protein domains (see all 6):
     IPR003959 ATPase_AAA_core
     IPR003960 ATPase_AAA_CS
     IPR027417 P-loop_NTPase
     IPR018359 Bromodomain_CS
     IPR001487 Bromodomain

    Graphical View of Domain Structure for InterPro Entry Q9ULI0

    ProtoNet protein and cluster: Q9ULI0

    UniProtKB/Swiss-Prot: ATD2B_HUMAN, Q9ULI0
    Similarity: Belongs to the AAA ATPase family
    Similarity: Contains 1 bromo domain


    ATAD2B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Numbers (IUBMB): EC 3.6.1.32 EC 3.5.1.152

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
    GO:0017111nucleoside-triphosphatase activity IEA--
    GO:0070577histone acetyl-lysine binding IDA--
         
    ATAD2B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ATAD2B:
     Synthetic lethal with Ras 

         1 MGI phenotypic allele for Atad2b (no phenotypes)

    ATAD2B for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ATAD2B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ATAD2B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ATAD2B

    miRNA
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    miRTarBase miRNAs that target ATAD2B:
    hsa-mir-21-5p (MIRT030851), hsa-mir-26b-5p (MIRT029473)

    Block miRNA regulation of human, mouse, rat ATAD2B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ATAD2B (see all 91):
    hsa-miR-3607-3p hsa-miR-411 hsa-miR-199a-3p hsa-miR-4272 hsa-miR-218-1* hsa-miR-30d hsa-miR-578 hsa-miR-30a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ATAD2B

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: ATAD2B (NM_017552)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ATAD2B
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ATAD2B

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATAD2B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ATAD2B
    Interactions:

        Search GeneGlobe Interaction Network for ATAD2B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ATAD2B (Q9ULI03 ENSP000002387894) via UniProtKB, MINT, STRING, and/or I2D (see all 225)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RBL1P287493I2D: score=1 
    SUPT16HENSP000002162974STRING: ENSP00000216297
    SSRP1ENSP000002784124STRING: ENSP00000278412
    HIRAENSP000002632084STRING: ENSP00000263208
    MCM3ENSP000002298544STRING: ENSP00000229854
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ATAD2B (ATD2B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ATAD2B gene (2 alternative transcripts): 
    NM_001242338.1  NM_017552.2  

    Unigene Cluster for ATAD2B:

    ATPase family, AAA domain containing 2B
    Hs.467862  [show with all ESTs]
    Unigene Representative Sequence: NM_017552
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000238789(uc002rej.4 uc002rei.4 uc002rek.4 uc010yki.2)
    ENST00000381024 ENST00000474583 ENST00000486610 ENST00000478885 ENST00000498006
    ENST00000458510 ENST00000366438 ENST00000439915(uc010exx.2)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ATAD2B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ATAD2B (see all 91):
    hsa-miR-3607-3p hsa-miR-411 hsa-miR-199a-3p hsa-miR-4272 hsa-miR-218-1* hsa-miR-30d hsa-miR-578 hsa-miR-30a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ATAD2B
    Predesigned siRNA for gene silencing in human, mouse, rat ATAD2B
    Clone
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    OriGene clones in human, mouse for ATAD2B (see all 6)
    OriGene ORF clones in mouse, rat for ATAD2B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ATAD2B (NM_017552)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ATAD2B
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ATAD2B
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ATAD2B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ATAD2B
      QuantiTect SYBR Green Assays in human, mouse, rat ATAD2B
      QuantiFast Probe-based Assays in human, mouse, rat ATAD2B

    Additional mRNA sequence: 

    AB033066.1 AF038204.1 AK023705.1 AK094821.1 AK125718.1 AK131301.1 BC037408.1 BC171846.1 

    11 DOTS entries:

    DT.99967671  DT.101956844  DT.97776105  DT.91650686  DT.40231078  DT.95261658  DT.91845828  DT.102842507 
    DT.425591  DT.86850973  DT.91836153 

    1 AceView cDNA sequence:

    CB988926 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ATAD2B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b
    SP1:              -                                         -                 -                                                         
    SP2:              -           -     -     -                 -           -     -                                                         
    SP3:              -           -     -     -                 -                 -                                                         
    SP4:                          -                                                                                                         
    SP5:                                                                                                                                    


    ECgene alternative splicing isoforms for ATAD2B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ATAD2B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATGTCTACT
    ATAD2B Expression
    About this image

    ATAD2B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ATAD2B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.467862
        Custom PCR Arrays for ATAD2B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ATAD2B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ATAD2B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Atad2b1 , 5 ATPase family, AAA domain containing 2B1, 5 88.27(n)1
    92.05(a)1
      12 (2.15 cM)5
    3208171  NM_001099628.11  NP_001093098.11 
     49174045 
    chicken
    (Gallus gallus)
    Aves ATAD2B1 ATPase family, AAA domain containing 2B 81.24(n)
    86.69(a)
      421972  XM_419982.4  XP_419982.4 
    lizard
    (Anolis carolinensis)
    Reptilia ATAD2B6
    ATPase family, AAA domain containing 2B
    87(a)
    1 ↔ 1
    1(140439231-140515902)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.70802 Transcribed sequence with weak similarity to protein more 76.43(n)    AL872229.2 
    zebrafish
    (Danio rerio)
    Actinopterygii atad2b1 ATPase family, AAA domain containing 2B 61.8(n)
    63.97(a)
      100331225  XM_002667424.2  XP_002667470.2 
    worm
    (Caenorhabditis elegans)
    Secernentea lex-16
    Protein LEX-1, isoform a (lex-1) mRNA, complete cd...
    31(a)
    1 → many
    IV(12079473-12084360) WBGene00008682
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YTA76
    Protein that localizes to chromatin and has a role...
    26(a)
    1 → many
    VII(1027370-1031509) YGR270W


    ENSEMBL Gene Tree for ATAD2B (if available)
    TreeFam Gene Tree for ATAD2B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ATAD2B gene
    ATAD22  
    12 SIMAP similar genes for ATAD2B using alignment to 6 protein entries:     ATD2B_HUMAN (see all proteins):
    VCP    PSMC5    PSMC1    KATNAL2    PSMC6    PSMC3
    NVL    ATAD2    DKFZp434E0418    PSMC2    DKFZp434K0126    ATAD1

    ATAD2B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ATAD2B (see all 3401)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs607018141,2
    C--23723588(+) ACACA-/C/CAC/CACAC/CACA
    TACACACACACACACACAC
    ACCAC
    4 -- int1 cds10--------
    rs1411828081,2
    C--23723588(+) ACACA-/CACACCAC 2 -- int10--------
    rs1131403101,2
    C--23732939(+) CCGAGA/GCGGGC 2 -- int10--------
    rs1406034231,2
    C--23742039(+) TTTTCTT/-TTTTT 2 -- int11Minor allele frequency- -:0.50NA 2
    rs32172671,2
    C--23751802(+) GATGGC/-AACAA 2 -- int11Minor allele frequency- -:0.50NA 2
    rs802617011,2
    C--23751802(+) GATGGA/C/GAACAA 2 -- int10--------
    rs576693141,2
    C--23774029(+) ACAAA-/CAAA/CAAA
    CAAACAAACAAA
    TAATA
    2 -- int11NA 2
    rs350935161,2
    C--23775848(+) AAAAA-/A/AA  
            
    TGCTA
    2 -- int11NA 2
    rs346499261,2
    C--23786655(+) TTAAA-/CAAAAA 2 -- int10--------
    rs44279741,2
    C,F--23809143(+) CAGCTA/TATTTT 2 -- int13Minor allele frequency- T:0.33NA 6

    HapMap Linkage Disequilibrium report for ATAD2B (23971534 - 24149984 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for ATAD2B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1080283CNV Deletion17803354
    esv2659738CNV Deletion23128226
    esv1350131CNV Insertion17803354
    nsv507003CNV Insertion20534489
    nsv214066CNV Loss16902084
    esv33590CNV Loss17666407
    nsv2640CNV Loss18451855
    nsv524917CNV Loss19592680
    nsv511769CNV Loss21212237
    nsv527636CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ATAD2B
    DNA2.0 Custom Variant and Variant Library Synthesis for ATAD2B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615347    OMIM disorders: --

    4 diseases for ATAD2B:    About MalaCards
    oligodendroglioma    tuberculosis    obesity    neuronitis


    ATAD2B for disorders           About GeneDecksing


    Export disorders for ATAD2B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ATAD2B gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with ATAD2B)
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    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2 Nagase T.... Ohara O. (DNA Res. 1999)
    3. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Histone recognition and large-scale structural analysis of the human bromodomain family. (PubMed id 22464331)2 Filippakopoulos P.... Knapp S. (Cell 2012)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. ATAD2B is a phylogenetically conserved nuclear protein expressed during neuronal differentiation and tumorigenesis. (PubMed id 21158754)1 Leachman N.T....Tucker R.P. (amp 2010)
    10. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54454 HGNC: 29230 AceView: KIAA1240.2 Ensembl:ENSG00000119778 euGenes: HUgn54454
    ECgene: ATAD2B H-InvDB: ATAD2B

    (According to HUGE)
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    HUGE: KIAA1240

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ATAD2B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ATAD2B gene:
    Search GeneIP for patents involving ATAD2B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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