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ASXL3 Gene

protein-coding   GIFtS: 47
GCID: GC18P031158

Additional Sex Combs Like 3 (Drosophila)

(Previous name: KIAA1713)
(Previous symbol: KIAA1713)
  See ASXL3-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Additional Sex Combs Like 3 (Drosophila)1 2
KIAA17131 2 3 5
Additional Sex Combs-Like Protein 32 3
BRPS2 5
Putative Polycomb Group Protein ASXL32

External Ids:    HGNC: 293571   Entrez Gene: 808162   Ensembl: ENSG000001414317   OMIM: 6151155   UniProtKB: Q9C0F03   

Export aliases for ASXL3 gene to outside databases

Previous GC identifers: GC18P029413 GC18P028018


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ASXL3 Gene:
ASXL3 (additional sex combs like 3 (Drosophila)) is a protein-coding gene. Diseases associated with ASXL3 include bainbridge-ropers syndrome. An important paralog of this gene is ASXL1.

UniProtKB/Swiss-Prot: ASXL3_HUMAN, Q9C0F0
Function: Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are
required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG
proteins are not required to initiate repression, but to maintain it during later stages of development. They
probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000018.9  NT_010966.15  NC_018929.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ASXL3 gene promoter:
         HFH-3   GR   GR-beta   C/EBPalpha   FOXI1   GR-alpha   RSRFC4   Hlf   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ASXL3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ASXL3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q11   Ensembl cytogenetic band:  18q12.1   HGNC cytogenetic band: 18q11

ASXL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASXL3 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P031158:  view genomic region     (about GC identifiers)

Start:
31,158,541 bp from pter      End:
31,331,156 bp from pter
Size:
172,616 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ASXL3_HUMAN, Q9C0F0 (See protein sequence)
Recommended Name: Putative Polycomb group protein ASXL3  
Size: 2248 amino acids; 241919 Da
Sequence caution: Sequence=BAB71186.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAD18599.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=CAB61377.1;
Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;
Secondary accessions: Q6ZMX6 Q96MU3 Q9UFC5
Alternative splicing: 2 isoforms:  Q9C0F0-1   Q9C0F0-2   (No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for ASXL3: NX_Q9C0F0

Explore proteomics data for ASXL3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ASXL3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_085135.1  
    ENSEMBL proteins: 
     ENSP00000465053   ENSP00000466073   ENSP00000269197   ENSP00000468024   ENSP00000466655  
     ENSP00000465634   ENSP00000466244   ENSP00000468264   ENSP00000467648   ENSP00000466030  
     ENSP00000468533   ENSP00000467907   ENSP00000464931  

    ASXL3 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for ASXL3

     
    Search eBioscience for Proteins for ASXL3 

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    Cloud-Clone Corp. ELISAs for ASXL3
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    Search eBioscience for ELISAs for ASXL3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR024811 ASX/ASX-like
     IPR028020 ASXH
     IPR024818 ASXL3
     IPR007759 DNA-dir_RNA_pol_delta/Asxl
     IPR026905 ASX-like_PHD

    Graphical View of Domain Structure for InterPro Entry Q9C0F0

    ProtoNet protein and cluster: Q9C0F0

    UniProtKB/Swiss-Prot: ASXL3_HUMAN, Q9C0F0
    Similarity: Belongs to the Asx family
    Similarity: Contains 1 PHD-type zinc finger


    Find genes that share domains with ASXL3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ASXL3_HUMAN, Q9C0F0
    Function: Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are
    required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG
    proteins are not required to initiate repression, but to maintain it during later stages of development. They
    probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By
    similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ASXL3           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for ASXL3:
     Decreased viability with cispl  Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ASXL3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ASXL3
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    miRNA
    Products:
        
    miRTarBase miRNAs that target ASXL3:
    hsa-mir-26b-5p (MIRT029464), hsa-mir-221-3p (MIRT024184)

    Block miRNA regulation of human, mouse, rat ASXL3 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate ASXL3:
    hsa-miR-10b* hsa-miR-217 hsa-miR-509-5p hsa-miR-3119 hsa-miR-509-3-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat ASXL3

    Gene Editing
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASXL3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ASXL3_HUMAN, Q9C0F0: Nucleus (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ASXL3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including ASXL3: 
              Polycomb & Trithorax Complexes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for ASXL3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ASXL3 (ENSP000002691974) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CBX8ENSP000002693854STRING: ENSP00000269385
    BAP1ENSP000004171324STRING: ENSP00000417132
    EEDENSP000002633604STRING: ENSP00000263360
    ENSG00000272333ENSP000002222704STRING: ENSP00000222270
    SMARCA2ENSP000002657734STRING: ENSP00000265773
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    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with ASXL3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ASXL3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ASXL3 gene: 
    NM_030632.1  

    Unigene Cluster for ASXL3:

    Additional sex combs like 3 (Drosophila)
    Hs.464876  [show with all ESTs]
    Unigene Representative Sequence: NM_030632
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000592288 ENST00000593195 ENST00000269197(uc010dmg.1 uc002kxq.2)
    ENST00000590189 ENST00000592541 ENST00000586596 ENST00000592349 ENST00000586948
    ENST00000586327 ENST00000588038 ENST00000585426 ENST00000588741 ENST00000590225
    ENST00000593235 ENST00000590973
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate ASXL3:
    hsa-miR-10b* hsa-miR-217 hsa-miR-509-5p hsa-miR-3119 hsa-miR-509-3-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ASXL3
    Predesigned siRNA for gene silencing in human, mouse, rat ASXL3
    Clone
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    GenScript: all cDNA clones in your preferred vector: ASXL3 (NM_030632)
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    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ASXL3
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ASXL3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ASXL3
      QuantiTect SYBR Green Assays in human, mouse, rat ASXL3
      QuantiFast Probe-based Assays in human, mouse, rat ASXL3

    Additional mRNA sequence: 

    AB051500.2 AK056450.1 AK091683.1 AK127502.1 AK131454.1 AL133050.1 

    6 DOTS entries:

    DT.99933428  DT.75100871  DT.101973826  DT.121087996  DT.40295371  DT.91961759 

    24 AceView cDNA sequences:

    BQ068526 BX280402 BQ070530 AB051500 BM505320 AK131454 AI218579 AK056450 
    AK127502 AI218578 AA447511 AX747127 AI239785 BG718347 BE145544 AK091683 
    BM509729 AI202664 BG193209 AW166277 AL133050 AI932670 AA448494 CB050239 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ASXL3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTTTAATA
    ASXL3 Expression
    About this image


    ASXL3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Adipose (Muscoskeletal System)
             Interscapular Brown Adipose Depot
     
     Testis (Reproductive System)
    ASXL3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ASXL3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.464876

    UniProtKB/Swiss-Prot: ASXL3_HUMAN, Q9C0F0
    Tissue specificity: Expressed in pancreatic islets, testis, neuroblastoma, head and neck tumor

        Pathway & Disease-focused RT2 Profiler PCR Array including ASXL3: 
              Polycomb & Trithorax Complexes in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASXL3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ASXL3 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Asxl31 , 5 additional sex combs like 3 (Drosophila)1, 5 83.31(n)1
    81.77(a)1
      18 (11.96 cM)5
    2119611  NM_001167777.11  NP_001161249.11 
     223448835 
    chicken
    (Gallus gallus)
    Aves ASXL31 additional sex combs like 3 (Drosophila) 75.64(n)
    73.12(a)
      421102  XM_419185.4  XP_419185.4 
    lizard
    (Anolis carolinensis)
    Reptilia ASXL36
    additional sex combs like 3 (Drosophila)
    66(a)
    1 ↔ 1
    GL343207.1(2608962-2713286)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia asxl31 additional sex combs like 3 64.74(n)
    59.58(a)
      100170177  XM_004915200.1  XP_004915257.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Asx6
    Additional sex combs
    15(a)
    1 → many
    2R(10391463-10399998)


    ENSEMBL Gene Tree for ASXL3 (if available)
    TreeFam Gene Tree for ASXL3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ASXL3 gene
    ASXL12  ASXL22  
    1 SIMAP similar gene for ASXL3 using alignment to 10 protein entries:     ASXL3_HUMAN (see all proteins):
    ASXL1

    Find genes that share paralogs with ASXL3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ASXL3 (see all 3150)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1856663761,2
    --31156551(+) TAGAAA/TGAAAA 1 -- us2k10--------
    rs1163227771,2
    F--31156668(+) TATAAT/CACACC 1 -- us2k11Minor allele frequency- C:0.01WA 118
    rs286668631,2
    C,F--31156729(+) TTCAGC/TGTGTT 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1416953451,2
    --31156788(+) TTTTCC/TAAAAC 1 -- us2k10--------
    rs1913094271,2
    --31156851(+) AGAATG/TATCAT 1 -- us2k10--------
    rs1827318311,2
    --31156859(+) CATATA/GCAGCT 1 -- us2k10--------
    rs1454473281,2
    C--31157035(+) TTTTTA/GAACAG 1 -- us2k10--------
    rs1380555891,2
    --31157093(+) GAATTA/GTTAAA 1 -- us2k10--------
    rs1875022641,2
    --31157223(+) GTGTAC/TGAAAA 1 -- us2k10--------
    rs1910848051,2
    --31157239(+) AAAGTA/GCTATT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ASXL3 (31158541 - 31331156 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ASXL3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2668525CNV Deletion23128226
    nsv131746CNV Insertion16902084
    nsv819880CNV Loss19587683
    nsv833618CNV Gain17160897

    Human Gene Mutation Database (HGMD): ASXL3
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ASXL3
    DNA2.0 Custom Variant and Variant Library Synthesis for ASXL3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615115   
    OMIM disorders: 615485  
    1 disease for ASXL3:    
    About MalaCards
    bainbridge-ropers syndrome


    Find genes that share disorders with ASXL3           About GenesLikeMe

    Genetic Association Database (GAD): ASXL3
    Human Genome Epidemiology (HuGE) Navigator: ASXL3 (1 document)

    Export disorders for ASXL3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ASXL3 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with ASXL3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Identification and characterization of ASXL3 gene in silico. (PubMed id 15138607)1, 2 Katoh M. and Katoh M. (Int. J. Oncol. 2004)
    5. Genome-wide association study of lung function phenotypes in a founder population. (PubMed id 23932459)1 Yao T.C....Ober C. (J. Allergy Clin. Immunol. 2014)
    6. Genome-wide pharmacogenetics of antidepressant response in the GENDEP project. (PubMed id 20360315)4 Uher R....McGuffin P. (Am J Psychiatry 2010)
    7. Genome-scale RNAi screen for host factors required for HIV replication. (PubMed id 18976975)1 Zhou H....Espeseth A.S. (amp 2008)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family. (PubMed id 16412590)1 Fisher C.L....Brock H.W. (Gene 2006)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80816 HGNC: 29357 AceView: KIAA1713 Ensembl:ENSG00000141431 euGenes: HUgn80816
    ECgene: ASXL3 H-InvDB: ASXL3

    (According to HUGE)
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    HUGE: KIAA1713

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ASXL3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ASXL3 gene:
    Search GeneIP for patents involving ASXL3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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