Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ASUN Gene

protein-coding   GIFtS: 45
GCID: GC12M027059

Asunder Spermatogenesis Regulator

(Previous names: chromosome 12 open reading frame 11, asunder, spermatogenesis...)
(Previous symbol: C12orf11)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Asunder Spermatogenesis Regulator1 2     GCT12 3
C12orf111 2 3     Chromosome 12 Open Reading Frame 111
Asunder, Spermatogenesis Regulator Homolog (Drosphila)1 2     Mat89Bb2
Spermatogenesis Associated 301 2     NET482
Cell Cycle Regulator Mat89Bb Homolog2 3     SPATA302
Germ Cell Tumor 12 3     Protein Asunder Homolog2
Sarcoma Antigen NY-SAR-952 3     

External Ids:    HGNC: 201741   Entrez Gene: 557262   Ensembl: ENSG000000641027   OMIM: 6150795   UniProtKB: Q9NVM93   

Export aliases for ASUN gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ASUN Gene: 
ASUN (asunder spermatogenesis regulator) is a protein-coding gene. Diseases associated with ASUN include sarcoma. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: ASUN_HUMAN, Q9NVM9
Function: Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring
to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for
proper spindle formation and execution of cytokinesis

Gene Wiki entry for ASUN (C12orf11) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_009714.17  NC_018923.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ASUN
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidASUN promoter sequence
   Search SABiosciences Chromatin IP Primers for ASUN

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASUN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p11.23   Ensembl cytogenetic band:  12p11.23   HGNC cytogenetic band: 12p12.3

ASUN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASUN gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M027059:  view genomic region     (about GC identifiers)

Start:
27,058,112 bp from pter      End:
27,091,259 bp from pter
Size:
33,148 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ASUN_HUMAN, Q9NVM9 (See protein sequence)
Recommended Name: Protein asunder homolog  
Size: 706 amino acids; 80225 Da
Subunit: Interacts with PAFAH1B1; this interaction may be required for proper recruitment of dynein complexes to
the nuclear envelope at prophase
Subcellular location: Cytoplasm
Miscellaneous: RNAi in HeLa cells results in a multinucleated phenotype
Sequence caution: Sequence=AAO65180.1; Type=Frameshift; Positions=414, 445, 483, 498, 507;
Secondary accessions: Q86WE2 Q96HM2 Q9BTX2 Q9NTB6 Q9NVM5

Explore the universe of human proteins at neXtProt for ASUN: NX_Q9NVM9

Explore proteomics data for ASUN at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NVM9

  • ASUN Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ASUN Protein Expression
    REFSEQ proteins: NP_060634.2  
    ENSEMBL proteins: 
     ENSP00000445645   ENSP00000261191   ENSP00000448215   ENSP00000448985   ENSP00000448467  
     ENSP00000446183   ENSP00000443066   ENSP00000443724  

    Human Recombinant Protein Products for ASUN: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ASUN
    Browse OriGene Protein Over-expression Lysates
    OriGene MassSpec for ASUN 
    OriGene Custom Protein Services for ASUN
    GenScript Custom Purified and Recombinant Proteins Services for ASUN
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005737cytoplasm ISS--

    ASUN for ontologies           About GeneDecksing



    ASUN Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ASUN
    GenScript Custom Superior Antibodies Services for ASUN
    Novus Biologicals ASUN Antibodies
    Search for Antibodies for ASUN at Abcam
    Browse Antibodies at Cloud-Clone Corp. 
    ThermoFisher Antibody for ASUN
    LSBio Antibodies in human, mouse, rat for ASUN 

    Assay Products for ASUN: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ASUN
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ASUN
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019355 Cell_cycle_regulator_Mat89Bb

    Graphical View of Domain Structure for InterPro Entry Q9NVM9

    ProtoNet protein and cluster: Q9NVM9

    UniProtKB/Swiss-Prot: ASUN_HUMAN, Q9NVM9
    Similarity: Belongs to the asunder family


    ASUN for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ASUN_HUMAN, Q9NVM9
    Function: Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring
    to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for
    proper spindle formation and execution of cytokinesis

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    ASUN for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ASUN 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ASUN

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ASUN 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ASUN 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ASUN
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ASUN
    SwitchGear 3'UTR luciferase reporter plasmidASUN 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ASUN
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ASUN

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ASUN
    Sirion Biotech Customized adenovirus for overexpression of ASUN

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ASUN (see all 6)
    OriGene ORF clones in mouse, rat for ASUN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for ASUN
    Sino Biological Human cDNA Clone for ASUN
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ASUN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASUN
    Sirion Biotech Customized lentivirus for stable overexpression of ASUN 
                         Customized lentivirus expression plasmids for stable overexpression of ASUN 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ASUN
    Search LifeMap BioReagents cell lines for ASUN
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASUN


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ASUN

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/592 Interacting proteins for ASUN (Q9NVM91, 2, 3 ENSP000002611914) via UniProtKB, MINT, STRING, and/or I2D (see all 592)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    INTS1Q8N2012, 3, ENSP000003857224MINT-7945693 I2D: score=1 STRING: ENSP00000385722
    INTS3Q68E012, 3, ENSP000003186414MINT-7945693 I2D: score=1 STRING: ENSP00000318641
    CBFBQ139511, 3, ENSP000004151514EBI-741429,EBI-718750 I2D: score=1 STRING: ENSP00000415151
    ZNF655Q8N7203, ENSP000003938764I2D: score=4 STRING: ENSP00000393876
    INTS6Q9UL033, ENSP000003102604I2D: score=1 STRING: ENSP00000310260
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis IEA--
    GO:0007346regulation of mitotic cell cycle IMP15737938
    GO:0030317sperm motility ISS--
    GO:0051301cell division IEA--
    GO:0080154regulation of fertilization ISS--

    ASUN for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ASUN

    Search CenterWatch for drugs/clinical trials and news about ASUN

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ASUN gene: 
    NM_018164.2  

    Unigene Cluster for ASUN:

    Asunder, spermatogenesis regulator
    Hs.505077  [show with all ESTs]
    Unigene Representative Sequence: NM_018164
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000538155(uc001rhj.4) ENST00000261191(uc001rhk.4 uc010sjk.2)
    ENST00000538016 ENST00000542392 ENST00000536232 ENST00000538727 ENST00000544548
    ENST00000538748 ENST00000537336 ENST00000539625
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ASUN
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ASUN
    SwitchGear 3'UTR luciferase reporter plasmidASUN 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ASUN
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ASUN
    Clone
    Products:
         
    OriGene clones in human, mouse for ASUN (see all 6)
    OriGene ORF clones in mouse, rat for ASUN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for ASUN
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ASUN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASUN
    Sirion Biotech Customized lentivirus for stable overexpression of ASUN 
                         Customized lentivirus expression plasmids for stable overexpression of ASUN 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ASUN
    OriGene qSTAR qPCR primer pairs in human, mouse for ASUN
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat ASUN
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASUN
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASUN

    Additional mRNA sequence: 

    AF274950.1 AK001222.1 AK001492.1 AK001499.1 AK225336.1 AK297948.1 AL137401.1 AY211927.1 
    BC003081.2 BC008368.1 

    7 DOTS entries:

    DT.112120  DT.100785055  DT.121172948  DT.95272219  DT.121172949  DT.121172954  DT.95272216 

    24/158 AceView cDNA sequences (see all 158):

    BE302258 AI569851 AU280249 BG026501 AA397916 BF222717 BM470394 AA723208 
    AI656136 BQ574211 BF111317 BU187861 BX956450 BE501608 AI341376 BM971078 
    BQ020134 AI400552 BF724897 AW024440 AI334783 BG029993 AI887764 BC003081 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ASUN (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^
    SP1:              -     -     -                                                                                                                                 
    SP2:              -                                                                                                                                             
    SP3:                                                                                                  -                                                         
    SP4:                                                                                                                                                            
    SP5:                          -                                                                                                                                 

    ExUns: 20
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for ASUN

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ASUN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGGAGCAAA
    ASUN Expression
    About this image


    See ASUN Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ASUN

    SOURCE GeneReport for Unigene cluster: Hs.505077

    UniProtKB/Swiss-Prot: ASUN_HUMAN, Q9NVM9
    Tissue specificity: Widely expressed. Tends to be up-regulated in seminomas compared to normal testis

        SABiosciences Custom PCR Arrays for ASUN
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ASUN
    OriGene qSTAR qPCR primer pairs in human, mouse for ASUN
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat ASUN
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASUN
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASUN
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASUN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ASUN gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Asun5
    Spata301
    RIKEN cDNA 4933424B01 gene5
    spermatogenesis associated 301
    88.67(n)1
    95.61(a)1
      6 (77.70 cM)5
    711771  NM_138757.21  NP_620096.21 
     1465496325 
    chicken
    (Gallus gallus)
    Aves C1H12orf111 chromosome 1 open reading frame, human C12orf11 83.71(n)
    94.19(a)
      418213  XM_416439.3  XP_416439.3 
    lizard
    (Anolis carolinensis)
    Reptilia ASUN6
    asunder, spermatogenesis regulator
    86(a)
    1 ↔ 1
    5(91064458-91086223)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.252202 Xenopus laevis transcribed sequence with moderate similarity more 77.85(n)    CA787931.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi39e092 wufi39e09 73.25(n)   334292  BC045349.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta asun1 asunder 48.17(n)
    43.59(a)
      41971  NM_079655.3  NP_524379.2 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_R02D3.41 Protein R02D3.4 42.85(n)
    29(a)
      176839  NM_067480.3  NP_499881.1 


    ENSEMBL Gene Tree for ASUN (if available)
    TreeFam Gene Tree for ASUN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/591 SNPs in ASUN are shown (see all 591)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0356734
    A colorectal cancer sample4--see VAR_0356732 S P mis40--------
    VAR_0508644
    ----see VAR_0508642 M T mis40--------
    rs30646141,2
    C--27057671(+) GAAACAT/-ATAAC 1 -- ds50011Minor allele frequency- -:0.50CSA 2
    rs2002614391,2
    C--27057672(+) AAACAC/TANNNN 1 -- ds50010--------
    rs105506121,2
    C--27057674(+) ACATA-/T/TA  
            
    ACATG
    1 -- ds50011NA 2
    rs1145511231,2
    F--27057735(+) AATCAA/GCCTAG 1 -- ds50011Minor allele frequency- G:0.03WA 118
    rs79567241,2
    C,F,A,H--27057739(+) AACCTA/GGTAAC 1 -- ds500122Minor allele frequency- G:0.06NS EA NA 2490
    rs1401461941,2
    C--27057782(+) CTTTAC/TGCTTC 1 -- ds50010--------
    rs1844276731,2
    --27057919(+) GAACAC/GATATG 1 -- ds50010--------
    rs1503359331,2
    --27057947(+) AGATAA/GAAACA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for ASUN (27058112 - 27091259 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ASUN: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ASUN
    DNA2.0 Custom Variant and Variant Library Synthesis for ASUN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 615079    OMIM disorders: --

    2 diseases for ASUN:    About MalaCards
    sarcoma    


    ASUN for disorders           About GeneDecksing


    Export disorders for ASUN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ASUN gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with ASUN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Asunder promotes dynein recruitment and centroso mal tethering to the nucleus at mitotic entry. (PubMed id 23097494)1, 2, 3 Jodoin J.N....Lee L.A. (2012)
    2. Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes. (PubMed id 12414650)1, 2, 3 Bourdon V....Chaganti R.S. (2002)
    3. Asunder is a critical regulator of dynein-dynactin lo calization during Drosophila spermatogenesis. (PubMed id 19357193)1, 3 Anderson M.A....Lee L.A. (2009)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator. (PubMed id 15737938)1, 2 Lee L.A.... Orr-Weaver T.L. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Immunomic analysis of human sarcoma. (PubMed id 12601173)1, 2 Lee S.-Y.... Scanlan M.J. (2003)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55726 HGNC: 20174 AceView: FLJ10637 Ensembl:ENSG00000064102 euGenes: HUgn55726
    ECgene: ASUN H-InvDB: ASUN

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ASUN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ASUN gene:
    Search GeneIP for patents involving ASUN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ASUN  
     OriGene qPCR primer pairs and template standards for ASUN   Browse OriGene Protein Over-expression Lysates  
     OriGene MassSpec something-or-other for ASUN   OriGene clones in human, mouse for ASUN  
     OriGene qSTAR qPCR primer pairs in human, mouse for ASUN   OriGene Purified Protein for ASUN  
     OriGene ORF clones in mouse, rat for ASUN   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ASUN   OriGene Custom Protein Services for ASUN  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ASUN
     QIAGEN SeqTarget long-range PCR primers for resequencing ASUN
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASUN
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ASUN
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASUN
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASUN
     GenScript Custom Purified and Recombinant Proteins Services for ASUN GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for ASUN
     GenScript Custom Assay Services for ASUN GenScript Custom Superior Antibodies Services for ASUN
     GenScript Custom overexpressing Cell Line Services for ASUN CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Search Regulatory tfbs for ASUN
     Search Chromatin IP Primers for ASUN
     Search RT2 qPCR Primer Assays in human, mouse, rat ASUN
     Search GNC Networks for ASUN
     SABiosciences Custom PCR Arrays for ASUN
     Search Tocris compounds for ASUN
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for ASUN
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ASUN antibodies
     Search for Antibodies for ASUN at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ASUN
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for ASUN
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASUN
     SwitchGear 3'UTR luciferase reporter plasmids for ASUN
     SwitchGear Promoter luciferase reporter plasmids for ASUN
     ThermoFisher Antibody for ASUN
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASUN
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ASUN
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ASUN
    Customized:
     lentivirus for stable overexpression of ASUN
     lentivirus expression plasmids for stable overexpression of ASUN
     adenovirus for overexpression of ASUN
     LSBio Antibodies in human, mouse, rat for ASUN
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ASUN gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4