Aliases for ASTL Gene
External Ids for ASTL Gene
GeneCards Summary for ASTL Gene
ASTL (Astacin-Like Metallo-Endopeptidase (M12 Family)) is a Protein Coding gene. GO annotations related to this gene include metalloendopeptidase activity and aspartic-type peptidase activity. An important paralog of this gene is MEP1A.
UniProtKB/Swiss-Prot for ASTL Gene
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity).